| HS Code | 281622 |
| Productname | Neostigmine (Prostigmin) Veterinary Grade API |
| Synonym | Prostigmin; Neostigmine methylsulfate; Neostigmine bromide; 3-[[(Dimethylamino)carbonyl]oxy]-N,N,N-trimethylbenzenaminium methyl sulfate |
| Casnumber | 51-60-5 (neostigmine methylsulfate); 114-80-7 (neostigmine bromide); 59-99-4 (neostigmine base) |
| Molecularformula | C13H22N2O6S (neostigmine methylsulfate); C12H19BrN2O2 (neostigmine bromide); C12H19N2O2 (neostigmine base) |
| Molecularweight | 334.39 g/mol (neostigmine methylsulfate); 303.20 g/mol (neostigmine bromide); 223.29 g/mol (neostigmine base) |
| Drugclass | Reversible acetylcholinesterase inhibitor; parasympathomimetic; quaternary ammonium anticholinesterase |
| Mechanismofaction | Reversibly inhibits acetylcholinesterase, increasing acetylcholine at cholinergic synapses and neuromuscular junctions. |
| Veterinaryindications | Equine intestinal atony/ileus, postoperative ileus, urinary retention, rumen atony; adjunct in myasthenia gravis; reversal of non-depolarizing neuromuscular blockade in selected species. |
| Dosageforms | Tablets; injections; capsules; powders; granules; premix; solutions |
| Routesofadministration | Oral; intravenous; intramuscular; subcutaneous |
| Appearance | White to off-white crystalline powder; colorless to slightly yellow solution |
| Solubility | Freely soluble in water; soluble in alcohol; practically insoluble in organic solvents |
| Ph | Approximately 4.0–6.5 in aqueous solution |
| Meltingpoint | Neostigmine methylsulfate decomposes on melting; typically reported above 145°C with decomposition |
| Puritygrade | Veterinary grade API; typically ≥98.0% assay on dried basis |
| Storageconditions | Store at controlled room temperature 15–30°C; protect from light and moisture |
| Shelflife | Typically 24–36 months in unopened original packaging |
| Packaging | Double polyethylene bags inside fiber drum or as requested; protect from moisture and light |
| Contraindications | Intestinal or urinary obstruction, peritonitis, asthma, bradycardia, recent gastrointestinal surgery, hypersensitivity |
| Adverseeffects | Salivation, lacrimation, urination, diarrhea, vomiting, bradycardia, bronchoconstriction, muscle fasciculations, convulsions |
| Antidote | Atropine sulfate for muscarinic effects; supportive care and veterinary supervision for severe toxicity |
| Typicaldose | Species-specific and product-specific; equine 0.01–0.04 mg/kg IV/IM; canine/feline 0.01–0.02 mg/kg IV/IM/SC; always consult a veterinarian |
As an accredited Neostigmine (Prostigmin) Veterinary Grade API for Tablets / Injections / Capsules / Powders / Granules / Premix / Solutions factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
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Competitive Neostigmine (Prostigmin) Veterinary Grade API for Tablets / Injections / Capsules / Powders / Granules / Premix / Solutions prices that fit your budget—flexible terms and customized quotes for every order.
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Tel: +8615365186327
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