Rutin

    • Product Name: Rutin
    • Alias: vitamin P
    • Einecs: 221-636-1
    • Mininmum Order: 1 g
    • Factroy Site: Yudu County, Ganzhou, Jiangxi, China
    • Price Inquiry: admin@ascent-chem.com
    • Manufacturer: Ascent Petrochem Holdings Co., Limited
    • CONTACT NOW
    Specifications

    HS Code

    578842

    Name Rutin
    Chemical Formula C27H30O16
    Molecular Weight 610.52 g/mol
    Appearance Yellow crystalline powder
    Solubility Slightly soluble in water, soluble in alcohol
    Sources Citrus fruits, buckwheat, apples
    Cas Number 153-18-4
    Melting Point 190-192 °C
    Category Flavonoid glycoside
    Uses Dietary supplement, pharmaceutical ingredient
    Taste Slightly bitter
    Stability Stable under normal conditions

    As an accredited Rutin factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Rutin, 100g: Supplied in a sealed, amber glass bottle with tamper-evident cap, labeled with product details, safety, and storage instructions.
    Shipping Rutin is shipped in tightly sealed containers to protect it from moisture, light, and air. It should be handled as a non-hazardous chemical, stored in a cool, dry place, and transported according to standard chemical regulations. Ensure proper labeling and documentation during shipping to maintain product integrity and compliance.
    Storage Rutin should be stored in a tightly closed container, protected from light and moisture, at room temperature (15–25°C). It should be kept in a cool, dry place, away from incompatible substances and sources of heat or ignition. Proper storage ensures its stability and prevents degradation. Handle under conditions that minimize dust generation and exposure to air to preserve its quality.
    Application of Rutin

    Applications of Rutin in Industrial Manufacturing

    Rutin is a flavonoid compound widely used in diverse industrial sectors, primarily leveraging its antioxidant, stabilizing, and chelating properties. The following sections detail core downstream applications based on industry-specific standards, formulation protocols, and established manufacturing routes in global supply chains.

    1. Pharmaceutical Preparations for Vascular Health

    Pharmaceutical manufacturers incorporate rutin into vascular protective formulations to support capillary integrity and reduce permeability. Producers blend rutin during the granulation or direct compression phases for solid oral dosage forms, focusing on precise content uniformity and stability to comply with monograph guidelines. Rutin enters tablet and capsule production lines following comminution, ensuring controlled particle size and content. End products include prescription therapies for chronic venous insufficiency and adjunctive treatments within hematology, exclusively marketed through licensed pharmaceutical channels adhering to local regulatory frameworks.

    Industry compliance standards

    • EP (European Pharmacopoeia) Monograph 01/2019:1140
    • USP–NF (United States Pharmacopeia – National Formulary) standards for Flavonoids
    • GMP (Good Manufacturing Practice) under PIC/S or FDA 21 CFR Part 210/211
    • ICH Q3A/B for impurities and residuals

    Typical usage ratio

    • 30–500 mg per tablet or capsule; batch-level formulation between 2% and 10% w/w depending on therapeutic endpoint and dosage size
    • Adjustment based on target label claim, tablet mass, active-excipient ratio, and bioavailability study outputs

    Downstream process integration

    • Dry blending with fillers, binding agents, and disintegrants in solid dosage mixing vessels
    • Integration post-micronization for improved dissolution profile in granulation or direct compression
    • Inclusion in powder filling for hard gelatin capsules
    • QC sampling performed after blending and compression to ensure homogeneity and potency

    Final product types

    • Prescription and OTC oral tablets
    • Gelatin or HPMC capsules for vascular health
    • Fixed-dose combination drugs for chronic venous diseases
    • Phytopharmaceutical finished dosage forms under traditional herbal medicine laws

    2. Food Supplement Manufacturing

    Producers in the nutraceutical sector employ rutin as a functional ingredient in food supplements aimed at antioxidant support and cardiovascular maintenance. Routine applies during premixing and granulation steps using stainless steel blending systems under HACCP-controlled environments. Content assays and stability studies dictate formulation strengths, and automated dosage systems dispense blends into final containers. Finished goods cross regulatory checks for flavonoid content, solubility, and declared nutrition panels prior to market distribution.

    Industry compliance standards

    • EFSA (European Food Safety Authority) Novel Food status and permitted lists
    • 21 CFR §172.510 (US FDA), permitted food additive status assessment
    • China National Food Safety Standard GB 2760–2022 for food additives
    • ISO 22000 Food Safety Management for supplement manufacturing

    Typical usage ratio

    • 30–250 mg per serving in multi-ingredient blends
    • Routine levels ranging from 0.1%–1% w/w in powder or tablet mix
    • Adjustment influenced by local maximum allowed intake and evidence from tolerated daily intake studies

    Downstream process integration

    • Blend with maltodextrin, vitamins, and minerals in industrial ribbon blenders
    • Wet granulation followed by compaction for chewable tablets or coated caplets
    • Filling into sachets, pouches, or effervescent tablet molds using high-speed packaging lines
    • Microbial and heavy metal testing conducted prior to containerization

    Final product types

    • Dietary supplement tablets and capsules
    • Functional powders for beverage mixing
    • Gummy vitamins with antioxidant claims
    • Single-ingredient or combined antioxidant supplement blends

    3. Cosmetic and Personal Care Formulations

    Industrial cosmetics producers integrate rutin in advanced skincare and anti-aging products due to its demonstrated free radical scavenging and skin conditioning abilities. Rutin disperses in aqueous or hydroalcoholic phases, with solubilization aided by surfactant or pH adjustments as required. Formulators standardize levels to fit within safety evaluations from SCCS and region-specific cosmetic ingredient guidelines. Batch compounding occurs in stainless steel reactors under controlled temperature, before homogenization and filling; routine batch QC confirms flavonoid content and microbial limits to support product release.

    Industry compliance standards

    • EU Regulation (EC) No 1223/2009 on Cosmetic Products
    • Cosmetic Ingredient Review (CIR) safety assessments
    • China NMPA Inventory of Existing Cosmetic Ingredients (IECIC)
    • ISO 22716:2007 GMP for cosmetic manufacturing

    Typical usage ratio

    • 0.01%–0.5% mass fraction in creams, serums, and emulsions
    • Lower percentages used for daily formulations, higher levels reserved for intensive or professional lines based on compatibility tests and stability validation

    Downstream process integration

    • Dissolution in aqueous or hydroalcoholic phase prior to emulsion formation
    • Co-blending with botanical extracts, vitamins, and antioxidants prior to cooling and preservation addition
    • Inline homogenization prior to bulk filling for viscosity and particle size control
    • Packaging performed in air-controlled rooms to avoid contamination and oxidation

    Final product types

    • Anti-aging facial serums
    • Hydrating and protective face creams
    • Post-sun and redness-reducing lotions
    • Specialist cosmetic ampoules for clinical settings

    4. Functional Beverage and Food Ingredient

    Major beverage and food companies incorporate rutin for enhanced nutritional value in functional drinks, dairy, and health bars. Manufacturers optimize solubilization using microencapsulation or co-extrusion with carriers to achieve clarity and uniform dispersal in liquid matrices. Dosing and integration follow strict adherence to regionally approved limits and are validated through sensory and accelerated shelf-life testing. Continuous inline blending and inline sterilization occur before bulk fill for beverages, while baked products coordinate addition alongside dry phase ingredients.

    Industry compliance standards

    • EU Regulation (EU) No 1169/2011 for labeling and novel foods
    • China GB 14880–2012 for food nutritional fortification substances
    • US FDA GRAS determination process and labeling regulations
    • ISO 22000 Food Safety Management certification for production traceability

    Typical usage ratio

    • 5–50 ppm in flavored beverages and fortified water
    • 0.01%–0.2% w/w in cereal bars, yogurts, or functional dairy
    • Ratio determined by target daily intake, solubility, and matrix compatibility studies in finished product

    Downstream process integration

    • Premix with carriers or solubilizers before addition to beverage or baking formulation
    • Microencapsulation process applied for heat-sensitive or clarity-specific uses
    • Post-pasteurization dosing using sterile injection systems for beverages
    • Final QC for dispersal uniformity and analytical verification of label claim

    Final product types

    • Functional soft drinks and sports beverages
    • Fortified dairy drinks and yogurts
    • Fiber and protein-enriched cereal bars
    • Ready-to-mix powdered health beverages

    5. Animal Feed Additive Manufacturing

    Feed producers add rutin to premixes for livestock, pets, and aquaculture species as an antioxidant and health support supplement. Rutin is applied in powdered or microgranulated form depending on downstream pelleting or extrusion methods. Bulk blending with primary nutrients and minerals ensures even distribution, with content verification completed prior to downstream high-temperature feed pelletization or spray-coating. Finished feed complies with national safe feed additive lists and is delivered through regulated distribution channels to animal producers.

    Industry compliance standards

    • EU Regulation (EC) No 1831/2003 on feed additives
    • AAFCO (The Association of American Feed Control Officials) Guidelines
    • China GB 7300.1018–2017 for feed additive use
    • ISO 22000 or FAMI-QS quality management systems for feed production

    Typical usage ratio

    • 2–50 mg/kg total feed, varying by animal species and product category
    • Species-specific adjustment based on EFSA or local regulations, and actual bioavailability studies under commercial conditions

    Downstream process integration

    • Blend into vitamin-mineral premixes for homogeneity
    • Direct addition at main mixer before extrusion for feed pellets
    • Dry spray-coating on finished pellets for heat-sensitive applications
    • Routine verification of uniformity by near-infrared or HPLC analytics

    Final product types

    • Poultry and swine compound feeds
    • Pet nutrition formulations
    • Aquafeed premixes for fish and shrimp
    • Mineral and antioxidant feed premixes

    Free Quote

    Competitive Rutin prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please contact us at +8615365186327 or mail to admin@ascent-chem.com.

    We will respond to you as soon as possible.

    Tel: +8615365186327

    Email: admin@ascent-chem.com

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    Certification & Compliance
    More Introduction

    Rutin: A Reliable Bioflavonoid Manufactured with Precision

    Real Insights from Our Manufacturing Floor

    Years on the line have taught us plenty about raw plant ingredients and the subtle art of getting consistency and purity right batch after batch. Rutin, a bioflavonoid glycoside most often sourced from Sophora japonica flower buds or buckwheat, stands out in the world of natural extracts not just for its complex chemistry but also for how much care each step of production requires. We’ve learned the hard way that shortcuts—from harvesting techniques to solvent choices—leave their mark on the finished product. The only way to keep meeting pharmaceutical and food standards is respecting every detail of that journey from field to final filter.

    Customers regularly ask about Rutin because demand hasn't waned, especially from supplement formulators who count on real antioxidant performance and precise dosing. Our standard Rutin model meets 95% purity by HPLC, which makes it suitable for nutritional use, food fortification, and even certain cosmetic solutions. Lower grades exist in the market but can come with excess plant residue, solvent traces, or variable moisture, which undermine both stability and appearance. We avoid those issues with tight control over sourcing and cleaning because we have our own contracted farms, have trained the harvest workers on best timing—usually close to flowering—and keep a close eye on incoming batches for both pest residue and pesticide compliance.

    The Physical Specs and the Work That Backs Them Up

    Each lot rolls out as a fine yellow powder with negligible odor and low moisture balance. You won’t see much deviation in particle size from us; we run each batch through precision sieves before packaging. Our testing lab works daily on calibrating the purity metrics, checking not only the final content but also common heavy metals, micros, and solvent residues. Storage conditions are another underrated detail: too much humidity pulls in clumping and color darkening, so we invest in proper climate-controlled storage and recommend customers do the same. That’s just an honest reality of any natural powder, especially one with delicate glycoside bonds.

    Many prospective clients are surprised by the role that trace impurities—like quercetin or kaempferol—can play if left unaddressed. Extracted plant materials almost never come out single-molecule pure without destructive steps, but we employ multiple rounds of ethanol extraction, filtration, and crystallization rather than relying on just one cut. This triple-process approach bumps up yield quality and minimizes degradation, a clear distinction from lots bought secondhand from loose networks of resellers where product origins blur and chemical stability gets lost early. Pharmaceuticals care about batch-to-batch reproducibility and full traceability, so that ends up being a dividing line.

    How Rutin Gets Used Beyond the Brochure

    Rutin goes into more than capsule bottles. Some manufacturers blend it into topical creams for its antioxidant effect. In food and beverage, it’s used to add a subtle color and help stabilize shelf-life due to its scavenging action on free radicals. It can boost the effectiveness of vitamin C in many blends. Nutritional tests have confirmed that Rutin tends to support healthy blood vessel walls, and for years has appeared in supplements aimed at supporting vascular health and inflammation reduction.

    We’ve worked with both multinational and niche players who don’t just want paperwork— they want evidence on actual composition and absorption. That’s forced us to not only supply standardized certificates but work closely with developers to match solubility needs, test heat stability at batch size, and package according to specific regulatory zones. Not every Rutin is made equal: we’ve seen samples on the secondary market come with variable moisture or show off-color changes that point to variable solvent evaporation. Those inconsistencies—absent from our production—end up undermining end product safety, especially in pharmaceutical or food sectors where lab testing gets intense.

    Setting Our Rutin Apart From the Market Crowd

    After years guiding production lines, what separates a substance with a good name from a generic powder is what happens before it leaves the plant. Customers deserve more than just a COA slip; they deserve an ingredient devoid of the kinds of pesticides or foreign particles that sometimes sneak in with bulk shipments sourced via gray channels or hasty brokers. We test incoming botanicals for over thirty different suspected contaminants before extraction even begins.

    Industrial buyers also know price alone just isn’t the deciding factor. One of the most common headaches for manufacturers is getting chunky, sticky, or damp material that clogs high-speed dosing and creates dust problems. Our in-house quality managers monitor moisture content tightly with real-time sensors and make reject calls at the packaging line if anything drifts above our strict cutoff. After many trials through the years, our standard mesh gives the best dispersion for both tablet and liquid blend partners.

    Some demand non-GMO, others want detailed allergen-free backing or full batch traceability from farming to final drum. We don’t parcel that job out—we hold longstanding auditing agreements both upstream and downstream. That gets noticed on audit day, especially in EU and US operations where proof and documentation count for more than verbal reassurances. Regulatory inspections push us to maintain not only ISO-compliant records but also keep up with changing contaminant detection limits, which have only gotten stricter in the past five years.

    Facing the Challenges in the Industry

    With disruptions in global logistics, price swings in raw botanicals, and tightening compliance rules around food-grade extraction, direct herb sourcing has only gotten more important. Reliable routine testing and hands-on plant visits allow us to spot issues at planting time, not just after product breakdown happens.

    Farm hands we train know what we aim for—a clean, mature harvest with buds picked at peak for Rutin content. Remote monitoring, image sharing, and cold-storage distribution after picking keep plant fibers from breaking down early. Some rivals rely on pooled sources or crop leftovers, introducing more variability and risking contaminants downstream.

    We treat solvent recovery and purity with the seriousness it deserves. By distilling and re-using food-grade ethanol on-site, we protect both product integrity and the safety of staff. Cheaper ethanol or single-use solvents can leave behind surprises—something you only discover once a third-party lab comes back with a red-flag reading. Our years of hands-on work taught us that “trust but verify” matters: not every Rutin on the market has survived enough checks to meet tight specs every single shipment.

    Customers Want Proof, Not Just Promises

    Whole supply chains rest on the silent reputation of ingredients that end up deep inside big-name finished products. Brand reliability depends on ingredients whose origin, handling, and quality controls are traceable and repeatable. Food and pharmaceutical manufacturers don’t want just a pretty powder; they want a lot that blends as predicted, meets microbial floors, and ships with the right paperwork every single time. Customers buying direct from us know their Rutin is produced under the roof of a single factory whose inspections our own management team witnesses monthly.

    For those formulating supplements or food products, handling surprises—either from product appearance or spec deviations—can easily unravel a launch timeline. We see it year after year in urgent calls from customers who tried lower-cost, brokered loads only to run into sticky dust, color shifts, or documented solvent residue. That’s the cost of not starting with a factory that cuts no corners from raw field to finished powder.

    The Ever-Changing Regulatory Landscape

    Market and consumer concern about traceability, purity, and safety have grown steadily. New requirements from EFSA, FDA, and emerging markets mean every batch needs to clear more data hurdles. Our documentation and trace sampling systems evolved with those standards long before official mandates forced the issue. That makes audits and import checks far less stressful for manufacturers down the line, who know they can pull up supporting documents at every stage.

    Sustainability and clean label movements also shaped Rutin production. Our chemists replaced certain extraction aids with naturally derived alternatives after thorough performance reviews, not because of trend pressure but because we saw faster regulatory approval and fewer supply chain disruptions. Product recalls cost everyone, and short-term savings by dodging compliance just don’t add up after a single problem shipment.

    We work closely with partners and clients to help them future-proof their own applications. That includes helping them design blending or tableting runs with the least material waste, supporting applications that demand more water solubility, or delivering smaller custom lots for test rolls.

    A Reliable Source That Stands the Test

    Quality, transparency, and honest relationships mark the difference in chemical manufacturing. Industry veterans can read a batch with their nose, eye, and handling—all before it ever lands in a lab. Our approach preserves that discipline and layers on full chain-of-custody records so decisions about sourcing and application can be made quickly and confidently.

    We keep training our staff, improving extraction bottlenecks, and reviewing every step of our QC reporting to remain ahead of the curve. The main benefit to customers comes not just in the uniform yellow powder, but in knowing exactly what sits behind each shipment—source farm, solvent recycling record, allergen cross-check, and a clear audit trail. That earns long-term trust with clients already pressed to meet tough regulatory reviews and competitive launches.

    We don’t chase every passing headline, but heavy supply chain disruptions over recent years taught the value of vertical integration and reliability. While many in the market shift to easy middleman solutions, we persist with direct, documented steps—from field to finished powder. That may never show up on the ingredient label, but it’s the story behind our Rutin’s reputation and why long-term partners keep returning.

    In this industry, it’s easy to get lost in a sea of “good enough.” Our experience as committed manufacturers taught us that settling for average closes more doors than it opens. For every new batch, we use every ounce of hard-won skill and attention, because every shipment reflects on our name and on the downstream partners who trust us. Rutin offers a window into the bigger values at the heart of responsible chemical manufacturing: traceability, consistency, and the deep wisdom of never cutting corners.

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