Products

LEKCare HAP (Hydroxyacetophenone)

    • Product Name: LEKCare HAP (Hydroxyacetophenone)
    • Alias: HAP
    • Einecs: 416-940-0
    • Mininmum Order: 1 g
    • Factroy Site: Yudu County, Ganzhou, Jiangxi, China
    • Price Inquiry: admin@ascent-chem.com
    • Manufacturer: Ascent Petrochem Holdings Co., Limited
    • CONTACT NOW
    Specifications

    HS Code

    578920

    Product Name LEKCare HAP (Hydroxyacetophenone)
    Chemical Name Hydroxyacetophenone
    Cas Number 99-93-4
    Molecular Formula C8H8O2
    Appearance Colorless to pale yellow crystalline powder
    Solubility Soluble in ethanol and propylene glycol, slightly soluble in water
    Odor Odorless
    Ph Range 5.0 - 7.0 (1% solution in water)
    Usage Preservative booster and skin-soothing agent in cosmetics
    Recommended Dosage 0.1% - 1.0%
    Stability Stable under normal storage conditions
    Storage Conditions Store in a cool, dry place, away from direct sunlight
    Safety Generally recognized as safe for use in personal care products

    As an accredited LEKCare HAP (Hydroxyacetophenone) factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing LEKCare HAP (Hydroxyacetophenone) is securely packed in a 1 kg white HDPE plastic bottle with a tamper-evident sealed cap.
    Shipping LEKCare HAP (Hydroxyacetophenone) is shipped in sealed, airtight containers to ensure product stability and prevent contamination. Containers are clearly labeled and packaged according to safety regulations for chemical transport. Shipping is carried out by certified carriers with appropriate documentation, supporting compliance with international and local chemical handling and transport standards.
    Storage LEKCare HAP (Hydroxyacetophenone) should be stored in a tightly closed container in a cool, dry, and well-ventilated area, away from direct sunlight and sources of ignition. Protect from moisture and incompatible substances such as strong oxidizing agents. Maintain storage temperature below 25°C. Ensure proper labeling and keep out of reach of unauthorized personnel.
    Application of LEKCare HAP (Hydroxyacetophenone)

    Applications of LEKCare HAP (Hydroxyacetophenone) in Industrial Manufacturing

    LEKCare HAP (Hydroxyacetophenone) delivers multifunctional performance in several speciality and industrial manufacturing fields, serving as a critical component in both formulation and processing. The following application scenarios highlight dedicated downstream use cases, process roles, compliance parameters, and finished product integration as implemented by global industrial users.

    1. Personal Care Preservative Systems

    Hydroxyacetophenone sees broad use as an active auxiliary in innovative preservative blends for personal care and cosmetic formulations, including creams, lotions, shampoos, and wet wipes. It provides additional protection against microbial contamination while enhancing overall preservative system stability, enabling manufacturers to reduce reliance on formaldehyde donors and parabens. Selection of concentration, combination with other preservatives, and adjustment according to specific pH ranges ensures reliable effectiveness for each product type, while regulatory scrutiny dictates strict control over formulation claims and traceability.

    Industry compliance standards

    • EU Regulation (EC) No 1223/2009 (Cosmetics Regulation)
    • US FDA 21 CFR 700 Subpart B (Cosmetic Product Regulations)
    • China Safety and Technical Standards for Cosmetics (STSC)
    • COSMOS Standard (for natural and organic cosmetics)

    Typical usage ratio

    • 0.1–0.7% w/w, typically adjusted between 0.2–0.5% depending on product type, pH, and accompanying preservative system

    Downstream process integration

    • Premixed with aqueous or oil phase prior to emulsification; added after primary emulsification or during cooling phase for thermosensitive formulas

    Final product types

    • Moisturizing creams and lotions
    • Baby wet wipes
    • Shampoos and conditioners
    • Facial cleansers and makeup removers

    2. Pharmaceutical Intermediate for API Production

    Hydroxyacetophenone acts as a precursor for synthesis of active pharmaceutical ingredients (APIs) in analgesics, anti-inflammatory agents, and certain antipyretic drugs. API manufacturers employ the material for its controlled reactivity during Friedel-Crafts acylation and condensation reactions. Critical process steps, including purification and scale-up synthesis, require strict batch traceability and quality management aligned with global pharma regulations, while compositional adjustment must ensure finished APIs meet targeted purity specifications for downstream formulation or tablet production.

    Industry compliance standards

    • ICH Q7 (Good Manufacturing Practice Guide for Active Pharmaceutical Ingredients)
    • USP–NF (United States Pharmacopeia–National Formulary)
    • European Pharmacopoeia (Ph.Eur.) Monographs
    • China Pharmacopoeia (ChP)

    Typical usage ratio

    • Stoichiometric quantities based on desired reaction pathway, typically 1.0–1.2 molar equivalents per target API molecule; adjusted for reaction efficiency and impurity control

    Downstream process integration

    • Charged in reaction vessel as starting material or intermediate; processed in multistep synthesis with in-process QC and solvent recovery

    Final product types

    • Analgesic tablets and capsules
    • Antipyretic and anti-inflammatory bulk drugs
    • Sterile injectable APIs (following further synthesis)
    • Complex pharmaceutical intermediates for custom manufacture

    3. Polymerization Additive for Resin Synthesis

    In industrial polymer manufacture, hydroxyacetophenone functions as a stabilizer and process additive during synthesis of polyesters, polyurethane dispersions, and specialty resins. Process engineers apply the material to control free radical activity, enhance color stability, and minimize premature cross-linking or yellowing during high-temperature processing. Dosage and stage of addition are critical for efficiency, as over-addition may affect final resin performance metrics. Compliance with end-use industry standards and continuous monitoring through online analytical systems are required to secure downstream approvals.

    Industry compliance standards

    • REACH Regulation (EC) No 1907/2006 (Substance Registration, Evaluation, Authorisation, and Restriction)
    • ISO 9001:2015 (Quality Management Systems for Manufacturing)
    • DIN EN ISO 14001 (Environmental Management in Chemical Processing)
    • UL 94 (Flammability Standards for Polymer Products where applicable)

    Typical usage ratio

    • 0.05–0.3% by total monomer weight; higher dosages possible in UV-sensitive or color-critical systems after pilot batch screening

    Downstream process integration

    • Introduced during monomer blending or in the prepolymerization step; monitored for residual content in final polymer analysis

    Final product types

    • Alkyd and polyester resins for industrial coatings
    • Polyurethane dispersions for adhesives and sealants
    • Specialty plastics for electronics encapsulation
    • Composite resin systems for automotive and industrial applications

    4. Food Contact Material Processing Aid

    Certain grades of hydroxyacetophenone serve as processing aids or antioxidant components during manufacturing of food contact polymers and coatings, such as PET bottles, can linings, and plastic food packaging films. Downstream processors utilize the chemical to improve thermal processing, minimize degradation during extrusion or molding, and extend shelf life of packaged goods by reducing formation of flavor- or odor-active breakdown products. Compliance requires maximum transparency regarding migration limits, as well as close alignment with food packaging regulations in target markets.

    Industry compliance standards

    • EU Regulation (EU) No 10/2011 on Plastics Intended to Come into Contact with Food
    • US FDA 21 CFR 177.1630 (Polyethylene Terephthalate Polymers for Food Contact)
    • China National Standard GB 9685 (Additives Used in Food Contact Materials and Their Usage Requirements)
    • BfR Recommendations (German Federal Institute for Risk Assessment, food packaging)

    Typical usage ratio

    • Less than 0.05% by weight in final polymer; processors determine dosage based on migration testing, specific packaging structure, and shelf-life requirements

    Downstream process integration

    • Compounded with resin pellets during melt blending; monitored for extractables and leachables prior to finished product release

    Final product types

    • PET beverage bottles
    • Multilayer food trays and containers
    • Food-grade flexible packaging films
    • Metal can linings for beverages and prepared foods

    5. Fine Chemical Synthesis for Agrochemical Intermediates

    Hydroxyacetophenone is widely incorporated in the synthesis of intermediates for agricultural chemicals such as herbicides, insecticide actives, and plant growth regulators. Producers use its aromatic structure and functional groups in controlled substitution or coupling reactions, ensuring high reactivity and consistent product yields. Strict batch segregation and contaminant testing at each step fulfill downstream product stewardship obligations, while calculated excess in stoichiometry allows for maximized conversion with minimal residuals in the technical concentrate.

    Industry compliance standards

    • FAO/WHO Guidelines on Good Manufacturing Practice (GMP) for Pesticides
    • ISO 9001:2015 (Quality Management for Agrochemical Producers)
    • Regulation (EC) No 1107/2009 (EU Plant Protection Products Regulation)
    • US EPA Registration and Tolerance Requirements (40 CFR)

    Typical usage ratio

    • 1.0–1.3 molar equivalents per target intermediate, with adjustment based on reaction efficiency and purity targets for technical-grade materials

    Downstream process integration

    • Added as a key aromatic nucleus in stagewise synthesis; isolated or purified before formulation into bulk agrochemical actives

    Final product types

    • Technical herbicide intermediates
    • Insecticide precursor compounds
    • Plant growth regulator components
    • Fungicide active ingredient building blocks

    6. Analytical Reagents and Chromatography Standards

    Analytical laboratories and chemical manufacturers utilize hydroxyacetophenone as a reference material and reagent in HPLC, GC, and spectrophotometric assays. Its defined purity and reliable UV absorbance profile allow for calibration standardization and system suitability testing across controlled environments. Laboratories demand far stricter control over documentation, impurity profiling, and certificate of analysis detail than bulk users, ensuring results meet regulatory standards for test methods in pharmaceutical, food, and environmental monitoring sectors.

    Industry compliance standards

    • ISO 17034 (General Requirements for the Competence of Reference Material Producers)
    • USP Reference Standards and Analytical Reagent Requirements
    • ISO/IEC 17025 (General Requirements for Competence of Testing Laboratories)
    • Pharmacopoeial recognition (e.g., BP, EP, USP for pharmaceutical testing)

    Typical usage ratio

    • Prepared as stock solutions of 0.01–1.00 mg/mL depending on method sensitivity and detection limits; actual volume defined per analytical protocol

    Downstream process integration

    • Dissolved directly as calibration, system suitability, or spiking standard during instrument setup or validation; process control includes purity verification and storage condition monitoring

    Final product types

    • Certified reference materials for HPLC calibration
    • Instrument system suitability standards
    • Analytical reagent kits for QC and R&D labs
    • Calibration mixes for spectrophotometric testing

    Free Quote

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    Email: admin@ascent-chem.com

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    Certification & Compliance
    More Introduction

    LEKCare HAP (Hydroxyacetophenone): Raising the Bar in Ingredient Integrity

    Real-World Know-How Born from Chemical Manufacturing

    Long hours go into each batch of LEKCare HAP. Here, every drum leaves the plant only when our process engineers and QC staff sign off with confidence. Customers often walk our production floor. They see for themselves that column purification, solvent handling, distillation, and quality checks happen with zero shortcuts. Benchmarks matter less than the trust we earn when a shipment meets both spec and real application needs, not just a passing tally on a QC report. Over the years, we’ve seen too many downstream failings caused by poor process hygiene, so we invested early in better containment and trace management.

    Hydroxyacetophenone: Chemistry with Long-Term Value

    Ask an R&D chemist or a production manager about hydroxyacetophenone and most will recognize its reputation in fields from personal care to fine synthesis. LEKCare HAP wears many practical hats: antioxidant, stabilizer, preservative enhancer, synthesis intermediate, and more. With its sharp melting point and mild scent, our product handles smoothly in sensitive formulas. Time and again, customers comment on how our grade holds up to repeated heat-cool cycles and exposure to tough pH ranges. Those are not marketing points but direct observations from the field.

    What Sets LEKCare HAP Apart from Run-of-the-Mill Grades

    LEKCare HAP follows the letter of every official monograph, but the real difference stands out in scale-up and day-to-day plant use. Many suppliers offer “hydroxyacetophenone,” but few achieve the same batch-to-batch control of residual solvents, trace acid, and color. We have customers who tried cheaper imports, only to learn how trace diketones or yellowish by-products degraded their finished formulation. We encountered the same issues before we reworked our own process—not just to scrape through assay numbers, but to wipe out contaminants that disrupt cosmetic appearance, polymer clarity, or fragrance quality.

    Traceability matters. Our controls go deeper than a test report. Each delivery includes a unique identifier mapped to the shift, batch, and reactor. Complaints about black specks or inconsistent crystal habits never linger; we chase every root cause and revise upstream steps as proven by in-house and customer feedback. It’s not glamorous, but it works.

    Specifications and Consistency

    Technical data can start to sound dry, yet in manufacturing, details determine success or failure. Our LEKCare HAP often comes at more than 99.8% purity (measured via HPLC), water below 0.2%, and color clear enough to pass even in transparent emulsions. Unlike generic grades, we refine particle size distribution so dosing, mixing, and dissolution go off without troublesome lumps. In automated dispensing systems, this saves wasted minutes per batch. In heat-sensitive formulas, our clean process eliminates hotplate residue and drop-out.

    Production staff stand behind these results every day—rejecting barrels on visual or smell mismatches, no matter how small. Our blend team takes pride in hearing from a skin-care formulator who switches to LEKCare HAP and sees both longer shelf life and fewer preservative-related complaints.

    Performance in Formulation & Manufacturing

    Several global cosmetics brands, as well as specialty ink and agrochemical firms, source directly from our plant. They ask not just for “hydroxyacetophenone,” but for product that resists darkening even in two-year accelerated stability tests. With LEKCare HAP, formulators report smoother blending in both non-ionic and cationic systems, fewer false positives in stability panels, and fewer ingredient-compatibility troubleshooting cycles.

    For those scaling up, consistency counts most. Months of R&D can disappear if a sourcing change introduces unseen impurities or shifts the behavior of phenolic intermediates. Our customers report that switching to LEKCare HAP means fewer pilot-batch surprises, faster troubleshooting, and predictable performance down the supply chain. We stay in the trenches with them—testing tweaks under production conditions and swapping data on how to address outliers.

    Application Versatility

    Hydroxyacetophenone earns its place as a multifaceted ingredient. In personal care, LEKCare HAP helps stabilize emulsions while working as a preservative booster, letting formulators reduce conventional actives like parabens or MIT. In polymers, coatings, and inks, our grade prevents yellowing and resin breakdown in both water- and solvent-based systems, supporting longer shelf life for packaged products.

    Pharmaceutical and agrochemical makers value our ability to control trace solvents and metallics, so LEKCare HAP can serve as a core intermediate with minimum downstream rework. Its solubility in alcohols and glycols removes the headaches that come from alternate stabilizers, which often require excessive heating or phase-matching. Even at high concentrations, we’ve designed our grade to avoid precipitating out, which matters most for continuous operations.

    Feedback from Users in the Field

    Feedback on LEKCare HAP rarely arrives in praise-filled emails. More often, it comes as reduced downtime, cleaner plant audits, or fewer complaints about preservative efficacy in hot and humid climates. Over the years, seasoned technicians have told us our HAP helps them avoid gelling, hazing, or unpredictable microbial blooms. These are not glamorous outcomes, but day in and day out, this proves invaluable.

    Buyers and plant chemists at both multinationals and local blenders share similar stories. They tried bargain alternatives, then called us after yellowing, off-smells, or unwanted residues forced urgent clean-outs. Their advice to new buyers: save money elsewhere, not on highly functional ingredients.

    Meeting Stringent Regulatory and Sustainability Demands

    Chemicals in our sectors must not only perform; they face ever-tightening regulatory oversight. Unlike fly-by-night resellers, our own process and every supporting record pass full audits by cosmetics, food, and industrial clients alike. Our HAP meets or exceeds global purity benchmarks, while regular monitoring of trace benzene, lead, arsenic, and other potential contaminants goes well beyond minimum statutory rules.

    We take sustainability as more than reporting. Reduced-waste distillation, responsible waste handling, and process water reclamation all matter when your plant has to answer for its impact. LEKCare HAP comes with a lower environmental footprint than the bulk of options from outside the region, thanks to local sourcing and fewer transport miles. Customers having to provide sustainability metrics to their end-users now rely on us because we offer real, traceable data, not just a certificate with empty claims.

    Understanding Pitfalls from Other Sources

    Many customers come to us after running into issues with poorly controlled HAP from other producers. Not all hydroxyacetophenone is created equal. Common complaints stem from inconsistent melting ranges, batch-to-batch color swings, or unknown odor notes. Down the line, these issues can ruin control over preservatives or antioxidants in a formula, alter pH unintentionally, or muddy up evaluations in sensitive applications.

    By focusing on upstream controls and not rushing the reaction or purification process, we have minimized those pain points. Each run is checked for trace-level contaminants, so the final user doesn’t face regulatory surprises or product recalls. We do not rely on third-party brokers to filter the obvious rejects—the responsibility rests with our engineers and techs from start to finish.

    Support Beyond the Drum

    Offering high purity alone does not solve every technical problem. Our team fields questions from production troubleshooters, scale-up engineers, and QA analysts every month. Whether it’s optimizing dispersion in a new base or chasing down an odor spike, we offer background data and process suggestions drawn from both lab and plant-floor observations.

    Should a problem arise, a direct line connects customer techs with the chemists who handled the batch, never a call center. We document root-cause investigations and follow through on changes in both our own and customers’ processes. This transparency has built working relationships that last cycle after cycle, even as formulas and markets evolve.

    Building Trust One Batch at a Time

    Some in our industry treat hydroxyacetophenone as a commodity. For those of us behind LEKCare HAP, every batch stands as a measure of our reputation. Our customers trust that what they receive each month will work just as the last, with no unwelcome surprises. This approach only works with tight monitoring and the willingness to reject or rework material in the rare event it misses the mark.

    Growth in demand for high-functioning chemical ingredients places stress on both producers and users. By focusing on ingredient stewardship, traceability, and process discipline, we keep production interruptions and field complaints at a minimum. Customers seeking smooth plant operations, compliant finished goods, and a partner who stands behind their ingredient often tell us they see real value in switching to LEKCare HAP.

    Staying Ahead in a Changing Landscape

    Years ago, basic batch reactions and crude purification might have been enough for most end uses. Rising quality standards and tougher downstream requirements—as well as consumer and regulator awareness—have changed this for good. We invest heavily in ongoing calibration, sensor upgrades, and real-time data feeds so each batch of LEKCare HAP reflects current best practices, not year-old standards.

    Whether supporting preservative-free personal care, stabilizing modern polymers, or feeding novel synthesis pathways, LEKCare HAP keeps pace with where our markets—and our customers’ problems—are headed. As chemical manufacturers, we believe true progress rests on more than simple claims of purity or compliance. It lives in the everyday results: fewer formulation headaches, sturdier finished products, and less stress for production teams under real-world pressures.

    Feedback Loop: The User’s Voice Matters

    No product introduction from a factory should be complete without mentioning who drives improvements. Our best ideas come from user comments and site visits. If your team faces a challenge or notices something off with your last batch, we document it, test it, then adjust if the evidence supports it. Market shifts, new applications, and regulatory changes all find their way into our ongoing revision process for LEKCare HAP.

    We are not perfect, but we listen more than we talk. The habits and insights formed from years on the factory floor mean that we appreciate just how many small details matter in making not just a working, but a trusted, ingredient.

    Pushing for Better Industry Standards

    Making hydroxyacetophenone that does more than just fit a certificate takes ongoing effort. Industry consolidation, price pressures, and short-term thinking often force corners to be cut by generic producers. Our approach with LEKCare HAP is to drive industry standards upward, not race to the lowest acceptable point. In practice, this means undergoing frequent third-party audits, cross-checking results with customer test labs, and opening our process records on request to qualified partners.

    This spirit of openness keeps us focused on both safety and innovation. As plant realities change and end-use challenges multiply, we remain committed to investing in capabilities that align with where our customers’ industries are headed.

    In Summary: More than Just Another Raw Material

    LEKCare HAP rewards customers who value robust plant operation, longevity of finished products, and clear traceability. The extra steps we take to ensure purity, batch consistency, and user support stem from years of listening to where things fail in the real world. For chemists, engineers, and buyers seeking reliable hydroxyacetophenone—not just a line item on a balance sheet—our experience working, adjusting, and improving this ingredient continues to pay off where it matters most.

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