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HS Code |
350513 |
| Chemicalname | Hydroxyacetophenone |
| Molecularformula | C8H8O2 |
| Molarmass | 136.15 g/mol |
| Casnumber | 99-93-4 |
| Appearance | White to off-white crystalline powder |
| Meltingpoint | 109-114°C |
| Boilingpoint | 285°C |
| Solubilityinwater | Slightly soluble |
| Density | 1.23 g/cm³ |
| Flashpoint | 146°C |
| Synonyms | 4-Hydroxyacetophenone, p-Hydroxyacetophenone |
| Application | Used in pharmaceuticals, perfumes, and chemical research |
| Odor | Slight aromatic odor |
| Stability | Stable under normal storage conditions |
As an accredited Hydroxyacetophenone factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | Hydroxyacetophenone is packaged in a 500g amber glass bottle, tightly sealed, with a printed label detailing chemical identity and hazard warnings. |
| Shipping | Hydroxyacetophenone should be shipped in tightly sealed containers, protected from light and moisture. It must be handled according to standard chemical safety procedures, including labeling and documentation. Shipping containers should comply with local and international regulations for chemical transport. Store in a cool, dry place during transit to prevent degradation or spillage. |
| Storage | Hydroxyacetophenone should be stored in a tightly closed container, in a cool, dry, well-ventilated area, away from sources of ignition, heat, and direct sunlight. Keep it separate from incompatible substances such as strong oxidizers. Ensure storage area is equipped to handle spills safely and that it is clearly labeled. Regularly check containers for leaks or damage. |
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Hydroxyacetophenone serves as a specialty additive and synthesis intermediate in several advanced material and formulation sectors. As a direct manufacturer, we closely monitor downstream requirements and regulatory developments to ensure consistent quality and compatibility for critical production steps. The following sectors illustrate our product’s established roles in end-use workflows.
Leading personal care formulators select hydroxyacetophenone for its gentle but effective support in preservative blends, especially in leave-on skincare and sensitive formula lines. Its application targets microbial control while maintaining sensory appeal and formula aesthetics. Downstream integration concerns pH stability, regulatory restrictions on traditional preservatives, and compatibility with botanicals and actives.
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2. Polymer and Resin StabilizersManufacturers of specialty polymers and alkyd resins introduce hydroxyacetophenone as an antioxidant and UV stabilizer, especially in applications exposed to photo-oxidative conditions. Its integration aims to delay discoloration, embrittlement, and loss of mechanical properties during both processing and end use. Regulatory controls target contact-sensitive articles and thus impact allowable inclusion rates. Industry compliance standards
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3. Pharmaceutical Intermediate SynthesisIn pharmaceutical synthesis, hydroxyacetophenone remains a key building block for manufacturing active pharmaceutical ingredients, especially in antispasmodic, anti-inflammatory, and analgesic drug families. Its functional group compatibility and defined impurity profile support cGMP manufacturing and scalable process yields. Regulatory oversight is strict, focusing on traceability and residuals. Industry compliance standards
Typical usage ratio
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4. Fine Fragrance and Aroma Chemical ManufacturingThe aroma industry utilizes hydroxyacetophenone as a synthesis intermediate in constructing key fragrance molecules, particularly for florals and musks, and as a direct ingredient for certain powdery, vanilla-like notes in luxury fragrance bases. Its position in the process allows creative perfumers to achieve stable, reproducible olfactory effects governed by IFRA and global labeling schemes. Industry compliance standards
Typical usage ratio
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5. Agrochemical Active SynthesisHydroxyacetophenone functions as a precursor in the synthesis of selective herbicide and fungicide actives within crop protection chemistry. Its structural properties facilitate defined coupling and cyclization reactions needed for active ingredient platforms. Regulatory scrutiny focuses on process purity, trace residuals, and downstream ecological safety of production lots. Industry compliance standards
Typical usage ratio
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Competitive Hydroxyacetophenone prices that fit your budget—flexible terms and customized quotes for every order.
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Manufacturing hydroxyacetophenone isn’t just about chemistry on paper. Every batch comes from plant floors where the pulse of daily production meets decades of practical adjustments. From feeding reactors with high-purity raw materials to dialing in reaction times under the watchful eyes of shift operators, we’ve learned that small tweaks can steer consistency, odor quality, and downstream processability.
Customers come to us with a spectrum of needs—cosmetic formulators needing smooth textures, polymer producers looking for tidy side reactions, and flavors and fragrances houses seeking that subtle aromatic note. Long ago, we learned experience helps in adjusting those controls and testing protocols so that what lands in the drum isn’t a generic powder, but a product you can integrate with less fuss or troubleshooting.
Lab results only tell half the story. For hydroxyacetophenone, its CAS number sets the identity, but meaningful control, color, and performance really separate the product. We’ve moved beyond just purity percentage; the color index, moisture content, trace impurity flags—they all matter for stability and final yield in your process. Typical assay values meet or exceed 99.5%, but we focus just as much on avoiding yellowing or sticky clumping, especially during storage and transport. Melt point checks land in the expected 108–112°C band, and we screen off-volatiles to avoid surprises in your mixing tank.
Each model—whether you need 4-hydroxyacetophenone or 2-hydroxyacetophenone—serves different downstream setups. Over the years, our team noticed fragrance and UV-absorbing applications found more value in the para-position variant, while certain specialty polymers benefited from select isomer blends. Our warehouse loads pallets based on your tonnage, but our chemists review small-scale samples for trials. Scaling up isn’t a problem; the lessons from batch failures in the early 2000s still keep our processes humble and repeatable.
A chemical only proves its value on the line. Hydroxyacetophenone happens to slot into places where a little molecular tuning means a cleaner process and better end products. Cosmetic manufacturers ask about hydroxyacetophenone for its anti-irritant and antioxidant properties; some switched from paraben preservatives after struggling with regulatory shifts and consumer pressures. Here, our knowledge about minimizing by-products like phenol really built trust with quality control teams. Polymer clients count on the ketone’s reactivity to open up new crosslinking chemistries, giving higher weather resistance or new melt-flow characteristics.
Our engineering team worked closely with household care brands in Asia to deal with solubility problems and color drifts in transparent liquid formulas. Hydroxyacetophenone helped them drop down on food-grade preservatives, cut cost, and still meet shelf-life demands, especially in humid markets. These outcomes don’t come from off-the-shelf commodities; they grow out of conversations and hundreds of trial-and-error samples crossing our lab benches.
You learn a lot in twenty years of bulk chemical manufacturing—especially that anyone can quote a spec, but only a few can keep the promise. Logistics throw up new problems each quarter. There’s the company in Brazil whose containers sweat during shipping, leading to trace caking and off-spec samples. Now, we line select shipments based on weather forecasts and improve packaging not for cost savings, but to safeguard your workflow.
We developed moisture-barrier liners and use kegs with real sealing; drums stand up to weeks in transit from our Asia plant to European users. Throughout, our team spent time understanding why batches that look identical on paper sometimes behave differently at customer sites. Root cause analysis often points to what’s invisible on a cert of analysis—microtraces of metal ions from pipework, or molecules that catalyze downstream yellowing. Our on-site and third-party audits focus on these small margins, all to cut headaches during your incoming QC testing.
Our business doesn’t end after the truck leaves the gate. We value feedback and site visits, working shoulder-to-shoulder with production supervisors, not just business development teams. One longtime partner flagged recurring filtration issues—they traced it back not to their own plant, but to slightly higher fines content from a raw material lot we’d never suspected would be a problem. A production process tweak on our side dropped sediments to negligible levels, keeping their downtime in check.
End-uses keep evolving. A decade ago, most hydroxyacetophenone left our site bound for the fragrance sector; today, it’s the cosmetics and new materials markets that drive upgrades. R&D teams test every batch for photostability, cleanliness, and impact on viscosity—in hair creams, lotions, UV-curable inks, and thermal transfer ribbons. These conversations help us update how we target impurity profiles: making a product to fit the future, not just refill shelves.
It’s easy to lump hydroxyacetophenone with other chemical building blocks. But after seeing the effects in a thousand applications, certain distinctions matter. Compared to simple acetophenone, the hydroxy group adds new hydrogen bonding, impacting solubility and oxidation resistance. In plastics, para-oriented hydroxyacetophenone delivers brighter products and fewer color shifts after weeks exposed on store shelves. Compared with parabens, hydroxyacetophenone’s profile chimes with clean-label and “no controversial preservative” movements—letting brands move faster toward modern regulatory targets.
Some competitors sell broad-spectrum blends or crude cuts downplayed as “industrial grade.” We push for consistent high-purity, not because the cert looks better, but because one lot out of range can shut down a batch and slow whole plants. It’s not the easy road—tightening up filtration, holding longer on drying, and spending more time on batch controls—yet the result is fewer customer complaints, less scrap, and more trust during audits. The little details set our hydroxyacetophenone apart from bargain imports or generic resellers.
We’ve seen firsthand how the success of your process starts even before you open the drum. Moisture, improper seals, or sunlight can impact hydroxyacetophenone stability—sometimes unseen until weeks later. Over the years, our packaging team updated drum linings to lock out water and oxygen. Some early lots sometimes showed caking after long marine shipments through steamy ports. After learning from those returns, we developed packaging that stands up to the real world. Our global warehouse network means shipments reach you fresher, cutting down on unplanned delays or quality dips.
Customers need predictability. So we offer flexibility in pack sizes—from fiber drums to IBCs—based on what fits with your fill lines or site storage capabilities. We reinforce batch segregation and labeling, not just for compliance, but so your operators can spot any anomalies fast. For those who run continuous production, lot-to-lot consistency remains key. Over time, this field-driven feedback shapes not just the hydroxyacetophenone you receive but also how we approach other key intermediates.
Process chemistry has seen big shifts in the last decade, and so has how hydroxyacetophenone fits into greener production. Our plant spent years cutting process solvent use by 30%, investing in inline recovery units that clean reusable washes for each batch. Rather than shipping solvents to waste, we refine and reuse at every stage. We source starting materials from long-term partners who share our low-emissions goals—ensuring not just compliance, but lower lifecycle impacts for your applications.
Sustainability isn’t a PR slogan in chemical manufacturing—it gets measured by the real changes we make in tons of waste, kilowatt-hours, and water consumed. We share our plant’s energy consumption and recycling rates with leading customers who demand transparency. Where possible, we use local sourcing for packaging, and our drums get preference for regional recycled materials to cut waste. Over time, these improvements help our clients build supply chains that hold up against rising scrutiny from both regulators and the public eye.
Natural disasters, shifting trade rules, and raw material fluctuations challenge chemical markets. Our hydroxyacetophenone lines keep running through it all due to years of investment in in-house capacity and diverse feedstock sources. Every crisis—from droughts disrupting key phenolic suppliers, to port bottlenecks—teaches us something new about safeguarding quantities for customers big and small.
Our planners map multiple months of production in advance, holding buffer stocks at satellite warehouses near main shipping lanes. Each year, our supply chain team reviews backup options—not waiting for shortages to trigger action. This keeps your process running, not stalling for suppliers to catch up. We monitor raw input quality at the gate, so impurities never slip through when supplies run tight. All of these steps echo the lessons learned from hands-on setbacks, not boardroom theory.
We’ve seen over and over that trust builds not from promises or paperwork, but from how products behave in real operations. Customers who scale up new products with us get more than timely deliveries. They gain partners invested in outcome—enough to share failures and help troubleshoot, not just celebrate wins. A paint manufacturer in Europe used our hydroxyacetophenone to solve delayed polymerization, a solution found only after weeks of joint lab work. These are the stories that fuel how we approach every new order.
Today’s end users look at more than molecules—they dig into traceability, ethical sourcing, and plant-level certification before they sign new supply agreements. Our job isn’t only to pass audits, but to ensure your brand doesn’t face costly recalls or bad press. We take customer site visits as an opportunity for unvarnished learning. Hearing about filter blinding, off-odor issues, or regulatory hurdles directly lets our technical and QC teams go beyond paperwork and into hands-on fixes. It’s this lived-in process that shapes every kilo shipped from our gates.
Chemistry doesn’t stand still, and neither do the rules around it. Over the years, regulatory compliance shaped much of our process—from switching out residual solvents to matching stricter impurity limits region by region. Our compliance staff works directly with regulators and industry groups, keeping us in step with new mandates on both raw materials and finished goods. For instance, as the European Chemicals Agency tightens rules on some aromatic compounds, we upgrade trace analyses and switch supplier grades quickly to shield our clients from regulatory delays.
Market trends, too, shape the hydroxyacetophenone people need. The rise of vegan and cruelty-free standards in beauty products forced us to drop animal-derived process aids and prove every input’s certification. Flavors and fragrance houses want lighter odor grades as clean-label preferences take root, so we work upstream with raw material partners to screen out off-notes and stick to batch-specific odor review. We don’t wait for customers to show us new paperwork demands—we go looking for them. This forward-thinking saves time in downstream product launches and approvals.
Chemical sales don’t stop at the invoice. Whether a cosmetics startup or a global polymer producer, our technical support team exists to walk through process hurdles, line changes, or product testing—offering direct feedback and real-world troubleshooting. We keep a technical archive with hundreds of tweaks, failures, and fixes, ready to share whenever a challenge arises. This isn’t about selling more; it’s about seeing our hydroxyacetophenone perform where it counts.
From recommending alternative dispersing aids for a sticky batch, to running stability studies for a new market’s climatic conditions, our technical staff have worked in labs and on plant floors. They help make the difference when you need to scale up, switch packaging, or fine-tune input ranges for regulatory reviews. This long-term support saves both sides rework and recalls, and it only happens when technical staff actually get their hands dirty in the field. That’s how real expertise grows.
Every year brings fresh uses for hydroxyacetophenone. Some clients innovate in personal care with lightweight leave-on products, relying on the antioxidant effect to keep formulations stable through months of heat or UV light. Others use it inside engineering plastics for critical goods shipped through tough climates. We share information about application studies and user results because the practical evidence of success matters more than theory or sales copy.
Our presence at industry expos and local conferences gives us a window into the fast-changing requirements of manufacturers. Meeting engineers, R&D formulators, and operations leaders face-to-face breaks through the noise of abstract specifications. Dozens of new case studies enter our technical database each year, building collective know-how for all users down the line. We take pride when our hydroxyacetophenone holds up in places others failed, be it a production-scale packaging run or a multi-year shelf-life trial.
Metrics like purity and appearance count, but we learned the hard way that “quality” in hydroxyacetophenone means knowing your product won’t spark batch failures, color drifts, or clumping under unusual storage. It means serving customers reliably through supply crunches and helping troubleshoot when things veer off plan. Most of all, it means you can depend on each drum, every time, for the exact function your process demands.
After years of hands-on work and tough lessons, our team knows that real value in chemical manufacturing comes from being open about both successes and flaws. This the guiding principle behind every order, shipment, and phone call with our clients. Hydroxyacetophenone stands as a result of countless decisions—big and small—each driven by people who care deeply about the chemistry and the trust it builds. This is what anchors our work and why we continue to invest in doing it better every year.