Chlorphenesin

    • Product Name: Chlorphenesin
    • Alias: 3-(4-chlorophenoxy)-1,2-propanediol
    • Einecs: 202-681-6
    • Mininmum Order: 1 g
    • Factroy Site: Yudu County, Ganzhou, Jiangxi, China
    • Price Inquiry: sales3@ascent-chem.com
    • Manufacturer: Ascent Petrochem Holdings Co., Limited
    • CONTACT NOW
    Specifications

    HS Code

    221890

    Name Chlorphenesin
    Cas Number 104-29-0
    Molecular Formula C9H11ClO3
    Molecular Weight 202.64 g/mol
    Appearance White crystalline powder
    Solubility In Water Slightly soluble
    Melting Point 77-79°C
    Boiling Point 145°C at 0.15 mmHg
    Usage Preservative in cosmetics and pharmaceuticals
    Mechanism Of Action Muscle relaxant by inhibiting reflex arcs
    Iupac Name 3-(4-chlorophenoxy)-1,2-propanediol
    Storage Conditions Store in a cool, dry place, tightly closed
    Ph 5.0 - 7.0 (1% solution)
    Odor Odorless
    Stability Stable under recommended storage conditions

    As an accredited Chlorphenesin factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Sealed amber glass bottle containing 100 grams of Chlorphenesin, labeled with product name, purity, batch number, and safety information.
    Shipping Chlorphenesin is shipped in tightly sealed containers to prevent moisture and contamination, typically under ambient conditions unless otherwise specified. Packaging complies with local and international regulations for non-hazardous chemicals. Ensure the container is clearly labeled and handle with care during transit to avoid spills or breakage.
    Storage Chlorphenesin should be stored in a tightly closed container, protected from light, heat, and moisture. Keep it at room temperature, typically between 15°C and 30°C (59°F and 86°F). Store in a dry, well-ventilated area away from incompatible substances such as strong oxidizing agents. Ensure containers are clearly labeled to prevent accidental misuse or contamination.
    Application of Chlorphenesin

    Purity 99%: Chlorphenesin with Purity 99% is used in topical dermatological formulations, where it ensures broad-spectrum antimicrobial efficacy and product safety.

    Molecular weight 214.25 g/mol: Chlorphenesin at molecular weight 214.25 g/mol is used in personal care emulsions, where it offers optimal solubility and consistent preservative action.

    Melting point 78°C: Chlorphenesin with a melting point of 78°C is used in cosmeceutical cream bases, where it provides stable formulation during thermal processing.

    Solubility 10 mg/mL (in water): Chlorphenesin with solubility 10 mg/mL is used in aqueous cosmetic serums, where it guarantees uniform preservative distribution.

    Stability temperature up to 40°C: Chlorphenesin stable up to 40°C is used in global export skincare products, where it preserves antimicrobial effectiveness under fluctuating storage conditions.

    Particle size <50 µm: Chlorphenesin with particle size less than 50 µm is used in powder-based formulations, where it enables homogeneous dispersion and maintains product texture.

    Low heavy metal content (<10 ppm): Chlorphenesin with low heavy metal content is used in hypoallergenic lotions, where it reduces the risk of irritancy and meets regulatory standards.

    Viscosity grade standard: Chlorphenesin with standard viscosity grade is used in gel-formulated personal care products, where it facilitates smooth application and enhances product stability.

    Free Quote

    Competitive Chlorphenesin prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please contact us at +8615365186327 or mail to sales3@ascent-chem.com.

    We will respond to you as soon as possible.

    Tel: +8615365186327

    Email: sales3@ascent-chem.com

    Get Free Quote of Ascent Petrochem Holdings Co., Limited

    Flexible payment, competitive price, premium service - Inquire now!

    Certification & Compliance
    More Introduction

    Understanding Chlorphenesin: Insight from the Manufacturer

    Our Experience in Crafting Chlorphenesin

    As a company with a long-standing commitment to the chemical industry, we have spent years perfecting the production of Chlorphenesin. Our production line runs on real feedback that comes from the laboratories and the manufacturing plants using our product every day. Every adjustment we make is based on what works in the real world, whether that's a tweak in purity levels, particle size or simply how easily the powder disperses in water. The process is never static. We scrutinize every step, from sourcing raw glyceryl derivatives to the final testing phase. Quality assurance doesn't mean closing our eyes and hoping for the best—it comes from constant checks and from never being satisfied with 'good enough'.

    What Sets Our Chlorphenesin Apart

    Chlorphenesin has built a strong reputation as a preservative and muscle relaxant, but its formulation varies greatly across the marketplace. Our process produces a high-purity powder, solid white and free of the gritty texture that often appears in lower grades. Longevity in different environmental conditions is a concern customers raise, so we focus intensely on moisture content—our batches routinely measure below the industry average, which means longer shelf life and less waste for downstream users.

    We do not cut corners by blending with cost-saving fillers. Adulteration risks both safety and efficacy, so each shipment faces strict scrutiny using HPLC and spectral analysis right before leaving our facility. The real value emerges when customers use our product and see fewer deviations in their batch records, or when a cosmetic formulator is able to create a microbe-stable formula without the headaches that come from variability.

    Relevance and Practical Application

    Chlorphenesin sits at the crossroads of pharmaceuticals, personal care, and topical formulations. Our core users know it not as a scientific curiosity but as a workhorse preservative and relaxing agent. In the pharmaceutical sector, manufacturers require materials that meet exacting standards. We apply the same mindset to Chlorphenesin as we do to our APIs: define every parameter, refuse to accept off-odors, discoloration, or contaminants, and document every step. For topical products—particularly in skin creams and serums—Chlorphenesin offers dual functionality. It inhibits bacterial growth, overcoming the unpredictability that comes from relying solely on parabens or formaldehyde releasers.

    One of our clients manufactures specialized ointments for athletes. They relay feedback about the consistency and smooth texture achieved in their end products. This feedback circles back to our own granular control during synthesis—meaning, the texture of our powder and its solubility profile directly help those formulators build better products without extra stabilization steps.

    Specification That Enables Consistency

    Customers often come to us citing challenges in prior experience. They reference inconsistencies—either a yellow tint, residue, or unexplained odors from alternate suppliers. We document our typical batch as containing Chlorphenesin content of over 99 percent, water content below 0.5 percent, and negligible organic volatile impurities. These aren't just numbers for a certificate—they translate to more controllable formulation processes.

    Rather than a uniform particle size, we offer several model grades ranging from extra-fine for leave-on haircare to standard for bulk mixing in pharmaceutical blisters. We arrived at these grades after trying to solve specific challenges raised by our partners. For instance, one large-volume user in dermocosmetics required a grade that visibly disappears without any clumping or grittiness, even under high humidity—so we fine-tuned our drying cycle and screening process to match.

    Chlorphenesin Against Other Preservatives

    The debate always circles back to preservatives—especially among companies keen on reducing consumer complaints linked to fragrance release, allergenicity, or regulatory scrutiny. Many alternative preservatives require higher concentrations to reach the same effect Chlorphenesin provides at a much lower dose. That means less impact on texture, scent or viscosity in the final product. Our R&D team frequently fields questions about substitutes, particularly as ingredient trends shift away from parabens and certain formaldehyde donors. Chlorphenesin resonates with manufacturers because it achieves microbial control without sacrificing user experience or regulatory position.

    We do see some customers compare Chlorphenesin directly with phenoxyethanol or isothiazolinones. The difference lies in the irritation profile and the comfort users report back. Chlorphenesin remains one of the few options that are tolerated across a broad group, including those with sensitive skin—a claim supported by years of post-market surveillance data that our team collects in cooperation with regulatory authorities.

    Use Case Stories from the Field

    It’s easy to focus on lab numbers, but field results drive our business decisions. One manufacturer in the Asia-Pacific region reported recurring batch failures due to contamination when using thinner, less pure preservatives. After switching to our Chlorphenesin, those failures fell dramatically—a finding that their QA department confirmed over a 12-month review. The root cause analysis came down to hidden impurities in the competitor’s material. Our double-filtration step, which some in the field overlook, removed these trace contaminants and translated to fewer recalls and greater brand trust for our client.

    Another example comes from a personal care brand that faced endless microcrack issues in their face cream packaging. Moisture ingress would cause product spoilage before the expiry date. Working together, we studied the interaction between preservative choice and packaging material. By moving to our low-moisture, micro-fine Chlorphenesin grade, they extended product stability by almost six months, reducing their returns and improving consumer loyalty. These stories stay with us—they are reminders that behind each drum of chemical, actual products and livelihoods take shape.

    Addressing Industry Shifts and Regulation

    Regulations for personal care products evolve fast. Over the last decade, authorities in Europe and North America scrutinized traditional preservatives. Several high-profile recalls—tied in part to allergenicity or breakdown under light—sparked a drive for safer, milder alternatives. Chlorphenesin, due to its track record, sits comfortably within these new frameworks, offering a lower risk profile and compliance with current standards. Our compliance officers maintain ongoing dialogue with key regulatory agencies. Their feedback doesn’t just reassure us—it forces us to keep documentation sharp, processes transparent and audits open at all times.

    Unlike bulk-supplied antimicrobials that struggle with fluctuating quality, our Chlorphenesin stays within specification no matter the climate, season or order volume. Manufacturers trust this consistency. Their technical teams rely on stable preservative action, minimal batch-to-batch variation, and full traceability—elements embedded in every certificate that follows our product.

    The Science Behind the Stability

    Producing Chlorphenesin isn’t just a matter of combining reagents in a vessel. Temperature control, reaction timing, washing techniques—each phase impacts the final structure and purity. For example, incomplete washing can introduce ionic impurities or leave behind synthetic byproducts. Over years of development, we designed a washing system that uses three cycles, each monitored for conductivity and pH. We track UV absorbance spectra as part of the final release process, catching any residual aromatic compounds that could pose issues downstream.

    Moisture content is a frequent headache for formulators, especially those working in hot or humid climates. We address this with proprietary drying technology that avoids thermal degradation but removes free water to near-trace levels. The proof—samples tested after six months in uncontrolled storage conditions still meet pharmaceutical acceptance criteria for moisture and assay.

    Feedback and Continuous Improvement

    Product feedback never stops. Cosmetic chemists, pharmaceutical engineers and technical QA teams send samples, data or simple anecdotes about batch performance. One cohort in the EU ran side-by-side preservative tests using multiple commercial grades. They found that our Chlorphenesin delivered more consistent anti-microbial protection at the lowest preservative load, allowing them to maintain pleasant textures and reduce reformulation costs. Sharing these field studies back with our production crew has shaped each refinement. If a customer flags incomplete dissolution in a specific matrix, our team trials new particle-cut recipes and rechecks the impact of pH in the cycling steps.

    Case studies from Latin America highlighted regional water supply differences impacting solubility. Our engineers now run daily solubility tests using variable hardness water, which led us to adjust our filtration configuration. As a result, distributors downstream now report fewer customer complaints tied to insoluble residues.

    Challenges and Solutions: Real-World Obstacles

    Scaling Chlorphenesin production isn't free from challenge. Raw material variability can spike prices or unpredictably impact impurity profiles. We deal with this honestly—building raw material partnerships that allow us direct say over processing parameters. If a shipment of glyceryl derivatives fails pre-screening, we don't accept it, and we adjust sourcing schedules in response. Realistically, the market always faces demand surges. Pharmaceutical clients sometimes triple or quadruple their orders overnight due to policy updates or new contract wins. Having a buffer stock policy lets us soften these shocks, and our logistics team maintains open lines with regular clients so nobody faces a critical shortage.

    Counterfeit or off-grade chlorphenesin in the global marketplace means buyers can land material that appears similar but works less reliably. We combat this by attaching machine-readable batch codes and anti-tamper seals on our drums — a small change that led to a sharp drop in unauthorized repackaging, ultimately improving supply chain security for everyone.

    Perspective from the Manufacturing Floor

    Daily, our technical team moves between the synthesis reactor, purification filters, and final packing line. Manufacturing Chlorphenesin means keeping hands-on experience close. QA inspectors cross-check batches against a physical gold standard sample held in-house. This standard isn’t a theoretical document—it’s a real jar of product manufactured under ideal conditions, available for direct comparison.

    Every person who touches the process, from operators to managers, knows the characteristics we stand behind: colorless powder, nearly neutral scent, quick-dissolving in formulation, and a complete absence of gritty residues. These features stem from real workplace experience— not from guesswork or an over-reliance on laboratory-only validation. Production mishaps do occur, and when they do, our traceability systems let us track every deviation back to its source, preventing recurrence and building a deeper collective expertise for the future.

    Working Directly With Customers

    We're not removed from the end-users. Large pharmaceutical groups, boutique skincare start-ups, and established cosmetic manufacturers regularly invite our technical staff to observe filling lines or troubleshoot preservative performance in real time. These visits aren’t just about offering expertise— they are learning exercises, highlighting real-world difficulties that data sheets can't predict. Seeing a filling nozzle clog due to unexpected particle size, or tackling microbial creep in a temperature-stressed facility, directly shapes the advice we provide and the technical bulletins we release.

    One customer’s move from a previous supplier's grade riddled with clumping to our micro-fine powder let them resume high-speed filling, avoiding downtime that cost thousands per hour. The feedback loop from their maintenance crew—not just purchasing or R&D—highlighted improvements that mattered most in their specific situation. This kind of practical partnership stands at the core of our operating philosophy.

    Environmental Considerations in Our Workflow

    Manufacturing today means considering more than product quality. Environmental audits shape our water usage practices, chemical handling, and emissions controls. Our process engineering team re-engineered the solvent recycling loop ten years ago, reducing both hazardous waste output and raw material consumption. We installed condensate return and water recirculation units, not for show, but based on actual energy savings and a reduced need for municipal water.

    In continued dialogue with customers looking to support greener sourcing, we document and share our environmental milestones—proof that good chemistry can run alongside responsible manufacturing. These standards sometimes mean extra steps, such as additional resin bed polishing or longer process cycle times, but they are decisions rooted in both business sense and community responsibility.

    Ongoing Research for Next-Generation Chlorphenesin

    Research doesn’t halt at a successful batch. Our laboratory team works in the background, mapping how minor molecular tweaks or new crystallization techniques might push the boundaries of Chlorphenesin’s performance. In-house stability testing runs parallel to external clinical or preservative challenge tests. The flavor of these projects comes straight from challenges voiced by our key partners—whether their needs involve extreme pH range compatibility, new regulatory labeling conditions, or unique viscosity management for novel product formats.

    Adapting process parameters for these evolving needs entails both risk and reward. We trial new models in pilot reactors, then scale up only after robust reproducibility tests. Many lessons learned in this environment spill over to our standard commercial runs, strengthening reliability and expanding application breadth.

    Looking Ahead—Shaping the Future of Chlorphenesin Supply

    The market’s demand for safe, predictable, versatile preservatives won’t slow down. As more regulatory agencies tighten ingredient lists and ban established but risky compounds, Chlorphenesin’s relevance continues to grow. The true test comes every single time a formulator or QC analyst opens a drum—does it perform as specified, batch after batch, regardless of where or when it was produced?

    From a manufacturer’s view, making Chlorphenesin isn’t just about checking boxes. It means standing behind every kilogram, recognizing that within each batch is a direct connection between our technical expertise, our partners’ ingenuity and the health outcomes of their end users. This sense of connection drives both our production process and our willingness to be transparent—a responsibility that guides both our day-to-day workflow and our plans for future expansion.

    Whether you are producing high-volume pharmaceuticals, agile indie skincare launches, or advanced topical therapies, Chlorphenesin brings high-impact, reliable performance to your table. From our manufacturing line to your final product, every detail reflects the knowledge acquired over years of real use, day-to-day troubleshooting, and ongoing dialogue with industry peers.

    Top