Products

65% Water-Soluble Azelaic Acid

    • Product Name: 65% Water-Soluble Azelaic Acid
    • Alias: azelaic-acid-65-ws
    • Einecs: 204-669-1
    • Mininmum Order: 1 g
    • Factroy Site: Yudu County, Ganzhou, Jiangxi, China
    • Price Inquiry: admin@ascent-chem.com
    • Manufacturer: Ascent Petrochem Holdings Co., Limited
    • CONTACT NOW
    Specifications

    HS Code

    273882

    Product Name 65% Water-Soluble Azelaic Acid
    Concentration 65%
    Solubility Water-soluble
    Form Liquid
    Color Clear to pale yellow
    Odor Mild
    Ph Range 4.0 - 5.5
    Primary Use Skin care
    Active Ingredient Azelaic Acid
    Preservation Preservative added
    Recommended Storage Cool, dry place
    Application Topical
    Compatibility Compatible with most skincare products
    Allergen Status Hypoallergenic
    Origin Synthetic

    As an accredited 65% Water-Soluble Azelaic Acid factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing The packaging is a 500g white HDPE bottle with a secure screw cap, labeled "65% Water-Soluble Azelaic Acid."
    Shipping 65% Water-Soluble Azelaic Acid is shipped in tightly sealed, chemical-resistant containers to prevent leakage and contamination. It is transported under controlled temperatures, with clear hazard labeling per safety regulations. Proper documentation and SDS accompany the shipment to ensure safe handling and compliance with international chemical transport standards.
    Storage 65% Water-Soluble Azelaic Acid should be stored in a tightly sealed container, away from direct sunlight and sources of heat. Keep it in a cool, dry, well-ventilated area, ideally at temperatures between 2–8°C (refrigerated). Avoid contact with incompatible substances. Ensure that storage areas are equipped with appropriate spill containment and that handling is performed with suitable protective equipment.
    Application of 65% Water-Soluble Azelaic Acid

    Applications of 65% Water-Soluble Azelaic Acid in Industrial Manufacturing

    Our high-content, water-soluble azelaic acid supports advanced performance and process efficiency in specialized industrial sectors. Below we outline key downstream applications, practical formulation data, integration steps, and reference compliance frameworks adopted by global manufacturers relying on this raw material.

    1. Dermatological Topical Formulations

    Major pharmaceutical and cosmeceutical companies use azelaic acid as an active in topical gels and creams treating acne, rosacea, and hyperpigmentation. The 65% water-soluble form permits direct aqueous-phase integration, supporting low-temperature emulsification, precise dosimetry, and faster dispersion in large-batch reactors. Manufacturers monitor raw material and batch quality per drug GMPs, from raw material sampling through final product release.

    Industry compliance standards

    • United States Pharmacopeia (USP) monographs
    • European Pharmacopoeia (Ph. Eur.)
    • 21 CFR Part 210/211 FDA cGMP for finished pharmaceuticals
    • ICH Q7 Guideline for Active Pharmaceutical Ingredients

    Typical usage ratio

    • 10–20% in topical emulsions and gels (adjusted to target OTC or Rx strength; EU and US regulators cap at 20%)

    Downstream process integration

    • Added to aqueous phase during cold or warm emulsification steps, followed by homogenization and viscous fill
    • Batch QC includes HPLC assay for content uniformity and identity

    Final product types

    • Acne treatment gels
    • Rosacea treatment creams
    • Skin depigmentation serums
    • Prescription dermal solutions

    2. Industrial Polyester Polyol Synthesis

    Polymer producers employ water-soluble azelaic acid as a dicarboxylic monomer for synthesizing specialty polyesters and polyols. The material's high purity allows consistent stoichiometry in esterification reactors running at 180–220°C. Manufacturers select feed ratios based on target polymer grade and application profile, with QA protocols covering both monomeric raw materials and finished resins according to sectoral and client-driven requirements.

    Industry compliance standards

    • REACH Annex VII/VIII for monomer import and registration
    • ISO 9001-certified quality system for continuous polymer processing
    • ASTM D1979 for acid value analysis in polyester resins
    • CFR Title 21 Part 175 for food-contact polymers if applicable

    Typical usage ratio

    • Up to 30 mol% of total diacid content in copolymer polyol synthesis, depending on targeted flexibility and water dispersibility

    Downstream process integration

    • Charged into main reactor with diols and chain extenders prior to bulk esterification
    • Melt blending with prepolymers for adjustment of molecular weight distribution

    Final product types

    • Water-dispersible polyester polyols
    • Flexible PU foam prepolymers
    • Resins for can coatings and coil coatings
    • Textile binder intermediates

    3. Cosmetic Ingredient for Leave-On Skin Care

    Major skin care brands incorporate water-soluble azelaic acid in facial creams and lotions designed for gentle brightening and texture refinement. The aqueous solution supports cold formulation and pH-controlled blending, minimizing batch-to-batch precipitation. Regulatory teams monitor INCI compatibility, finished product testing, and compliance with cosmetic notification systems in target markets.

    Industry compliance standards

    • EU Regulation (EC) No 1223/2009 on cosmetic products
    • Cosmetic Ingredient Review (CIR) safety assessment
    • China NMPA (formerly CFDA) ingredient registration
    • ISO 22716 GMP for cosmetics manufacturing

    Typical usage ratio

    • 3–10% w/w in facial serums and emulsions (higher inclusion above 10% only in prescription ranges)

    Downstream process integration

    • Premixed in aqueous phase post-pH adjustment, followed by slow addition of emulsifiers and actives
    • Post-batch microbiological testing for preservative efficacy and stability

    Final product types

    • Daily-use brightening creams
    • Hyperpigmentation targeting serums
    • Non-comedogenic moisturizers
    • Dermocosmetic leave-on sprays

    4. Preservative Boosters and Functional Additives for Waterborne Paints

    In architectural and industrial coatings, water-soluble azelaic acid works as a component in preservative booster systems and functional additives. It modifies microbial resistance and enhances the stability of waterborne formulations. Coating manufacturers optimize its dose based on pigment load, binder matrix and regulatory constraints specific to end-use applications, with extensive in-plant validation and VOC compliance testing.

    Industry compliance standards

    • EU Biocidal Products Regulation (BPR, Regulation (EU) 528/2012) for in-can preservatives
    • US EPA TSCA Inventory listing for additive use
    • ASTM D2486 scrub resistance and D3960 VOC emission limits
    • ISO 16000-6 for VOC determination in indoor coatings

    Typical usage ratio

    • 0.3–2.0% total solids (tuned according to susceptibility to in-can microbials and binder compatibility)

    Downstream process integration

    • Incorporated during the let-down phase together with dispersants and pigment concentrates
    • Tested in pilot batches for biostability and resistance to microbial contamination

    Final product types

    • Low-VOC architectural wall paints
    • Industrial waterborne primers
    • Exterior anti-mold façade coatings
    • Wet-state preservative concentrates for the paint industry

    5. Biodegradable Lubricant and Coolant Fluid Production

    Manufacturers of environmentally sensitive hydraulic fluids and metalworking coolants use azelaic acid in bio-lubricant ester synthesis. The water-soluble character improves reactant handling and ester formation with polyols under mild conditions. Strict adherence to environmental and toxicity regulations at the formulation and finished product stages ensures market acceptance in sensitive sectors such as food processing and forestry hydraulics.

    Industry compliance standards

    • OECD 301B ready biodegradability testing
    • ISO 15380 for lubricants — biodegradable hydraulic fluids
    • EU Ecolabel criteria for lubricants
    • Restriction of Hazardous Substances (RoHS) Directive 2011/65/EU (for support equipment exposure)

    Typical usage ratio

    • 18–25% of total acid content in polyol esterification for base oil synthesis, calculated for viscosity and pour point targets

    Downstream process integration

    • Charged in main batch with base polyols; water removed under vacuum as reaction proceeds to endpoint
    • Residual acid monitored for final neutralization and packaging

    Final product types

    • Biodegradable hydraulic base fluids
    • Metalworking coolant concentrate esters
    • Food-grade lubricants (NSF H1 compliant)
    • Chainsaw and forestry equipment oils

    Free Quote

    Competitive 65% Water-Soluble Azelaic Acid prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please contact us at +8615365186327 or mail to admin@ascent-chem.com.

    We will respond to you as soon as possible.

    Tel: +8615365186327

    Email: admin@ascent-chem.com

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    Certification & Compliance
    More Introduction

    65% Water-Soluble Azelaic Acid: Precision and Performance for Modern Applications

    Our Journey to a High-Purity, Water-Soluble Solution

    A generation ago, the market barely offered azelaic acid in a water-soluble form. Most relied on finely ground, powder-based azelaic acid, which often complicated formulation and restricted performance. Our team faced these realities firsthand. Years of feedback from partners in skincare, industrial processing, and polymer modification showed a clear frustration: standard suspensions left residue, clogged equipment, or turned up insoluble crystals during blending. Developing a stable, 65% water-soluble azelaic acid required retooling our own production lines and investing in continuous purification and solubilization technology.

    Through direct collaborations with end-users who formulate advanced cosmetic gels, pigment dispersions, and chemical cleaners, we learned that a true solution—not a suspension—creates consistent results and eliminates guesswork. Today, our 65% model stands as a high-load, crystal-clear liquid that does not separate or form precipitates after dilution.

    Specifications that Shape Your Process, Not Just a Document

    We scale our production to deliver a 65% azelaic acid solution measured at a typical pH range of 3.5–4.5, with minimal trace impurities. Manufacturing within this window, we watched as batches holding tighter controls yielded less odor, lower color, and better reactive compatibility with surfactants, alkalis, and acids. Our filtration, based on ultrafiltration and tight ionic threshold management, ensures the solution pours smoothly, dissolves instantly in both cold and warm water, and integrates seamlessly with active organic ingredients.

    Technicians in R&D and industrial operations frequently say that ordinary 20–40% azelaic acid solutions require tedious dilution and do not achieve high-concentration reactions without clouding or settling out. With our 65% liquid, a single pour can hit a higher dosage target with less volume, streamlining scale-up from pilot phase to full manufacturing. That density gives formulators breathing space when designing leave-on skin products or industrial degreasers where ingredient size and batch viscosity matter.

    Practical Value Across Industries: A Direct Manufacturer’s Perspective

    Cosmetic chemists, coatings engineers, and cleaners’ producers often describe old habits: dissolving powdered azelaic acid with strong bases, coping with stubborn sediment, or cleaning clogged lines for hours. As the originator of this 65% water-soluble form, we have tested batch after batch in actual formulation lines. The solution fully mixes in hydrogels, oil-in-water emulsions, and even tough blends containing reactive amines or strong oxidizers. Seasonal variations in water quality or processing temperature have minor influence on the clarity or stability, which our long-term customers confirm through their own QA logs.

    Azelaic acid’s natural, bio-based roots from grains and seeds often appeal to formulators pursuing greener label claims. We refine each batch from top-grade dicarboxylic acid feedstock using oxidation and crystallization steps under positive pressure. Our on-site QC lab runs titration, HPLC, and microfiltration checks—processes we have refined, not just for compliance, but because rework and off-target product cost real money in lost manufacturing time. Partners in skincare will quickly recognize that high-purity azelaic acid brings milder sensory profiles; it stings less at active use-levels and does not trigger pH swings that defeat preservation systems. When engineers at plant-based polyamide lines ask for liquid azelaic acid that retains reactivity in molten state, our 65% format stands up without fouling extruders or requiring pre-mixes.

    Real-World Use: Experience From the Factory Floor

    Daily production teaches us that a high-content, water-soluble azelaic acid handles far more safely and cleanly than dust-prone powders. Liquid forms offer more accurate dosing on automated lines and virtually eliminate airborne dust concerns—protecting both workers and sensitive electronics. One example involved a biotech partner shifting from dry azelaic acid to our 65% solution for their fermentation feedstocks; process analysts noted improved substrate blending, higher titers, and less filter cake at scale.

    Formulators in skincare frequently aim for active concentrations around 5–15%. Our liquid makes it simple: pipette or pump by simple volumetric calculation. It eliminates the margin for error when mixing with deionized water or emulsifiers, and doesn’t clog filters or require batch pre-wetting. Maintenance crews have commented that our solution rinses clean from mixing tanks and hoses, reducing downtime and water consumption.

    Polymer labs choose high-content azelaic acid to lower cycle time in polyamide and polyesters, since the free-flowing liquid absorbs faster and causes fewer temperature stratifications. Staff at a leading waterborne coatings formulator reported that pigment grind times fell by over 20%, and mixer torque stayed below threshold even when ramping up batch size. In each of these cases, the replacement of powders and suspensions with our 65% solution delivered smoother, more repeatable results—and sometimes, higher output per shift.

    Comparing Our 65% Solution With Conventional and Competitive Grades

    Many years producing azelaic acid in multiple formats revealed key contrasts worth considering in any operation. Old-school powders—often rated 99%-plus by purity—deliver raw value by weight but create downstream headaches: they resist quick dissolution and produce hotspots that defeat even high-shear mixers. The water-insoluble crystals typically form small agglomerates, which then float or settle, creating batch-to-batch variability in active content. It’s not uncommon for QA teams to rework or discard entire lots due to uneven blending or residue in finished emulsions.

    Suspensions, generally offered at 10–40%, ease some of the handling concerns but still struggle to deliver high active loads without stability issues. At elevated concentrations, older suspension grades quickly separate, so formulators keep shaking containers or resorting to secondary solubilizers. This habit adds cost, increases ingredient listings on labels, and sometimes produces unwanted foaming, especially in sensitive cosmetics or technical cleaners.

    In contrast, our 65% water-soluble model delivers:

    The high content also means that a manufacturer can ship and store more active material in less space, shaving logistics costs in both raw goods and finished products. Over years of working with both start-ups and multinational brands, we have seen that bulk purchasers increasingly favor liquid inputs that cut warehouse footprint and waste. No more breaking up rock-hard bags or managing inconsistent inventory: a single drum or tote of the 65% solution can replace several pallets of powder, with almost zero loss.

    The Direct Impact on Product Innovation

    Many partners mention that streamlined azelaic acid dosing encourages real innovation in their final goods. For skin care, formulators find the 65% solution a reliable backbone for combining with vitamin C, niacinamide, and plant extracts. There’s no batch gritting or sedimentation to challenge transparent serums or light gels—where clarity is king. One team working on anti-acne masks told us their switch to water-soluble azelaic acid both improved spreading properties and accelerated regulatory submission, since active verification turned straightforward.

    In industrial settings, process owners report more aggressive corrosion inhibition and scaling prevention when using direct soluble azelaic acid. These outcomes trace back to our manufacturing experience: cutting particle size and tuning ionic charge allows azelaic acid to bond or chelate more uniformly, even in hard water or hostile thermal conditions. The product’s high purity and flexible packaging—ranging from small kegs to bulk tankers—make it an easy fit for continuous or batch production.

    Facing Industry Challenges, Not Just Selling Product

    Real manufacturing demands more than good chemistry; it involves logistics, compliance, and trust. Over the years, our teams have met countless shipments delayed by weather or customs surprise, bottlenecks in drum handling, and the need to ship under temperature-controlled conditions when required. Our liquid solution tolerates standard transport and long-haul shipping far better than diluted suspensions or unprotected powders. Partners in tropical regions frequently request performance guarantees, so we stress-test each batch for stability at a full range of temperatures, including freeze/thaw cycles.

    COSMOS and REACH compliance come up weekly in our certification audits. Our facility logs each intermediate and finished batch, ensuring full traceability and batch authentication. While paperwork creates extra work, our long production history allows us to streamline certification for clients needing ingredient safety files. These steps reflect daily manufacturing choices: maintaining segregated lines to prevent cross-contamination, running trace metal and microbiological analytics, capping every drum under nitrogen, and batch-coding every delivery.

    Closing the Loop: Listening to Users Boosts Product Performance

    Every batch shipping out the door tells us something. Gel manufacturers call about batch thinning or thickening. Cleaner formulators want custom blending help. Water treatment engineers sometimes complain about trace color; we tackle each challenge head-on by adjusting reactant feed ratios or refining downstream clarification. Our own QA feedback loops drive improvements—a practice learned from the hardest, most detail-demanding buyers in Europe, the United States, and Asia.

    Our staff routinely visits customers’ plants to watch the solution at work. We take pride in collaborating directly at the kettle, whether to troubleshoot foaming or to spot potential downstream gelling caused by cross-linkers. This practical, shop-floor perspective steers our product development. For example, last year’s trial of a higher-alkali neutralization protocol originated from a single customer’s concern about residual yellowing during storage. We ran dozens of tests, modified process flow, retrained operators, and cut color spikes in subsequent lots by over 60%.

    Such feedback encourages us to maintain open lines for technical service, not just sales bookings. It’s common for us to blend small development lots with partner brands or to run pilot programs with customers who seek record-keeping transparency or custom viscosity modifications. Results from real-world use keep us grounded and direct us toward continuous improvement.

    Environmental and Safety Insights Born From Direct Practice

    Handling chemicals every day means safety is more than just a policy. The shift from dust-heavy powders to a water-soluble, pumpable azelaic acid solution reduced the risk of respiratory exposure for our team. Where once we suited up in heavy PPE to load reactors, line operators now measure liquid directly with no visible dust and no mess on the floor. Fewer airborne particles inside the plant means less risk of product cross-contamination and a safer station for material transfer crews.

    Our site maintains strict water management and waste minimization protocols. Soluble forms of azelaic acid simplify utility water recycling; rinse cycles complete in a fraction of the time compared to scrubbing powder residue. This practical shift allowed us to lower our plant’s water footprint—both a real cost savings and a win for sustainable operations. Environmental auditors walk the plant every quarter, comparing usage logs, and have confirmed these savings year over year.

    Over recent cycles, the option to ship in larger liquid containers means fewer packaging waste streams. Liquid-bound azelaic acid ships with less breakage risk, reducing the number of rejected shipments and accidental discharges in transit. This direct experience—watching pallets move through the dock and keeping incident rates low—has convinced us that the 65% solution stands as the safest, greenest step forward for bulk azelaic acid handling.

    Solutions to Industry Pain Points: Lessons From Direct Production

    Manufacturing chemistry is a constant lesson in problem-solving. Each step, from raw dicarboxylic feedstock selection to final monitoring, brings opportunities to address common user headaches. Years spent in direct production have taught us that batch stability and easy handling anchor any good chemical ingredient. We built our 65% water-soluble azelaic acid on that real-world knowledge.

    We now proactively help clients set up storage conditions, recommend dosing tools, and troubleshoot application outcomes before the first tanker leaves the plant. Several clients appreciate collaborative QC testing, where our teams coordinate on viscosity, color, and active titration to match specialized process requirements. Technical support does not end at the dock; it continues through integration, scaling, and batch scale validation.

    Just as importantly, we have learned that clarity and transparency win trust. Our typical product documentation—Certificate of Analysis, batch histories, raw analytical data—are openly shared with customers. Fielding technical questions about pH drift, bioburden, or batch-to-batch variation has honed our manufacturing practices and kept us alert to emerging trends, such as demands for vegan certifications or non-GMO batch declarations.

    Innovation, Adaptation, and the Road Ahead

    Producing high-content, water-soluble azelaic acid locates us at the center of many push-and-pull trends: cleaner beauty, rapid industrial change, and ever-finer performance standards. Our work does not end at meeting the status quo. Investment in R&D and close partnership with forward-thinking users shapes our roadmap—often in direct response to their stated ambitions for more concentrated, safer, and more sustainable inputs.

    Continuous pilot testing, plant upgrades, advanced filtration methods, and even new surfactant blends mark our journey toward ever-clearer, ever-higher performing azelaic acid liquids. In cosmetic, industrial, and polymer fields, our high-load water-soluble solution unlocks performance that powder and low-content solutions simply cannot match.

    With a daily focus on consistency, transparency, and technical partnership, we have built our 65% water-soluble azelaic acid product into a tool for formulators, engineers, and operators who demand more than a standard commodity. Every gallon produced and every shipment delivered assures our partners of both experience and innovation—drawn from years of hands-on, factory-driven improvement.

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