|
HS Code |
343020 |
| Name | Rutin |
| Chemical Formula | C27H30O16 |
| Molecular Weight | 610.52 g/mol |
| Appearance | Yellow crystalline powder |
| Solubility | Soluble in water and ethanol |
| Cas Number | 153-18-4 |
| Source | Found in buckwheat, citrus fruits, and other plants |
| Melting Point | 190-195°C |
| Synonyms | Vitamin P, Sophorin |
| Uses | Antioxidant, capillary strengthener, dietary supplement |
| Storage Conditions | Store in a cool, dry place away from light |
| Stability | Stable under recommended storage conditions |
| Taste | Slightly bitter |
| Boiling Point | Decomposes before boiling |
| Toxicity | Low toxicity at recommended doses |
As an accredited Rutin factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | The 100g Rutin chemical comes in a sealed, amber glass bottle with a clear label indicating product name, purity, and handling instructions. |
| Shipping | Rutin is typically shipped in sealed, moisture-proof containers to preserve its stability and quality. It should be transported at ambient temperature, away from direct sunlight and incompatible substances. Appropriate labeling and accompanying safety data sheets are provided, and all packaging complies with relevant transportation regulations to ensure safe and secure delivery. |
| Storage | Rutin should be stored in a cool, dry, and well-ventilated area, away from light and moisture. Keep it tightly sealed in its original container to prevent contamination and degradation. Avoid exposure to strong oxidizing agents and excessive heat. Ideally, storage temperature should be below 25°C (77°F). Ensure proper labeling and keep out of reach of incompatible substances. |
Competitive Rutin prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please contact us at +8615365186327 or mail to sales3@ascent-chem.com.
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Tel: +8615365186327
Email: sales3@ascent-chem.com
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Rutin has earned a respected place in our production line, not out of trend, but from years of real-world testing and demand across industries. Our journey with this natural flavonoid started over a decade ago, and along the way, we have seen how its applications and performance stack up compared to other flavonoids and plant extracts. Unlike many products that pass through a supply chain with little oversight, we control the process from the beginning, which shapes both our understanding of its true value and the way we talk about it.
Our focus on the exact extraction and purification of rutin gives us insight others in distribution rarely see. You notice the nuances between batches, the importance of solvent choice, and the issues that show up in end-use if you cut corners. Sticking with a standardized process — one we’ve tested countless times — means customers get dependable results, whether they use rutin in food, pharmaceuticals, or cosmetics.
Rutin is not simply a single, homogenous ingredient. Our main specification, which we label as ‘Rutin NF95’, refers to a product that achieves a purity above 95 percent, measured by HPLC. We rely on the full spectrum UV-VIS method to confirm identity and validate the batch—after learning that some traditional colorimetric methods misread subtle impurities.
Moisture content, if it slips over 5 percent, can tighten up flow or shift the affected batch’s shelf life. We constantly adjust drying times and vacuum settings based on the humidity in the air, an approach that sidesteps many performance issues downstream. Particle size takes careful attention, too. Overmilling generates fines that can drift in handling or react with packaging — something customers find out if the manufacturer is inattentive. We choose a grind that optimizes dispersibility and process behavior, not just what reads best on a spec sheet.
The product we ship is a yellow-green crystalline powder, not the off-grey some traders send out. We only move it after a full panel of tests for heavy metals, pesticides, and microbial load, all run inside our own quality control lab — brought about after seeing too many rejections in our early years from relying on external labs. In practice, keeping everything on one campus lets us see QC issues before they hit a customer’s line.
Rutin extraction starts long before the solvents touch the flower. The source material, Sophora japonica buds, comes from growers we have worked with for years. We look for harvest timing and drying conditions that minimize the natural variability in raw flavonoid content. Dried material left in the sun too long exposes itself to oxidation, lessening the yield and consistency – we only accept timed, shade-dried buds. These decisions sound minor until you notice the downstream batch loss when a poor crop slips through.
We use a hydroalcoholic solvent system, running multiple extractions to make sure we aren’t leaving behind useful product or dragging out unwanted byproducts. After filtration, each batch passes through a low-temperature concentration process. Skipping this step leads to a cloudy end product or, worse, a batch prone to thermal degradation. The isolation of rutin from the concentrate uses a crystallization method we have refined over several years, shifting solvent polarity and temperature to optimize the size and purity of resultant crystals.
From there, each batch undergoes repeated washings and drying at precisely regulated temperatures. Small changes in heat can set off a sequence of browning or caking, both of which trace back to the close control — or lack thereof — during drying. Our years of process adjustment mean this stage is rarely a cause of customer complaints from us, even though it remains a common pain point in outsourced rutin supply.
We reject the ‘commodity’ mindset when it comes to producing natural extracts. The goal is not to scrape by with minimums, but to observe the small process parameters that make a product better-quality, longer-lasting, and easier to blend or dissolve later.
Rutin sits at a unique intersection between food ingredients, pharmaceutical excipient, and cosmetic formulations. Calls about its applications come in from every direction, but we notice several main themes from our long-term customers.
In the pharmaceutical sector, manufacturers rely on rutin as an antioxidant and vascular protector. Our clients developing formulations for capillary health and chronic venous disorders report that formulation stability depends directly on rutin purity and the absence of trace solvents. Issues with taste and color stability rarely come up for those using our batch-controlled supply, but we’ve seen cases elsewhere where a more variable rutin ingredient led to tablet rejection in clinical manufacturing.
The food and beverage sector pulls rutin for its antioxidant capacity and as a labeling-friendly ingredient suitable for clean label claims. Here, flavor and solubility count for even more. We regularly bring in sensory panels to assess taste impact in model beverages or fortified foods. Clients producing functional teas or meal replacements get more reliable results from our refined version, particularly when they need low taste impact and consistent color.
Cosmetic manufacturers turn to rutin for its calming effect on sensitive skin and support for products aimed at reducing redness. Texture, color, and trace contaminant levels are crucial for these users, too. Difficulty dissolving in base creams or visible undissolved flecks point back, almost always, to subpar grinding and screening in production.
Some businesses ask whether using rutin, instead of other bioflavonoids, makes a noticeable difference in outcome. In our direct experience, the question comes down to outcomes in stability, taste, and bioactivity. Rutin, with its high phenolic content, provides stronger antioxidant properties compared to many cheaper plant powders. We have seen, batch after batch, fewer complaints about off-tastes in finished goods. Rutin glycosides tend to resist oxidation longer than aglycones — which means a chocolate or beverage using rutin resists color changes and bitterness creep more reliably. Medical clients update us about differences seen in dissolution testing between our rutin and lower-grade commercial versions; the minutiae of purity and particle size shift pharmacokinetic outcomes.
It’s impossible to talk about rutin without comparing it to quercetin and other flavonoids. This is a question we hear almost daily. Behind the sales lines, the reality is that each compound holds distinct properties. Rutin includes a sugar component (rhamnoglucoside) attached to quercetin, changing both its physical behavior and absorption in the body. We see the effect right away in manufacturing: rutin stays more stable under light and air during processing, while aglycone forms like quercetin may darken or lose activity over time.
The real-world benefit comes out especially in foods and beverages. Rutin imparts less bitterness compared to straight quercetin or citrus bioflavonoids. Producers who use generic citrus extracts often report persistent issues with taste masking, which rarely arises with our batches of rutin. In pharmaceutical application, the stability and slower breakdown of rutin aid formulation teams seeking consistent release and shelf life. A product based on rutin stays within label claims for antioxidant content longer than most of its cousins, as confirmed by shelf life testing across a range of conditions.
Lower-cost plant polyphenol products can be inconsistent. We’ve evaluated samples of grape seed, green tea, and citrus extracts from a range of sources. While these have their own advantages, the variability from plant strain, climate, season, and processing technologies shows up in nearly every analytical run. Rutin from Sophora japonica avoids some of this — the plant is less sensitive to environmental swings, and our role in overseeing the entire chain anchors our control over the final product.
The movement toward clean label and ‘transparent’ ingredient sourcing changes the landscape further. Customers want to know where and how the active ingredient reached their line. Our engagement back to the farm level, and investment in in-house purifications, lets us track and document every batch in ways bulk traders or relabelers simply cannot match.
Challenges emerge constantly in rutin manufacturing, regardless of a company’s credentials or track record. From our vantage as a true producer, several hurdles have shaped the way we operate.
Raw material variability tops the list. Not every harvest matches prior years, and flavonoid content swings can affect yield, purity, and extraction profiles. Long-term relationships with farmers, paired with pre-harvest inspections, buffer against most surprises. We have integrated rapid test kits in the field, so unusable crops never enter our production pipeline.
Another pain point centers on contaminants, from pesticide residues to heavy metals like lead and arsenic. In our early years, batches occasionally failed internal tests, prompting us to trace input lots back to individual plots of land. Since tightening our supply agreements and launching direct field audits, these failures now rarely, if ever, show up — and our customers gain greater peace of mind.
Solvent residues represent another risk. Each processing stage removes more, but speed can tempt shortcutting. Adhering to slow, progressive concentration steps, combined with in-line GC analysis, ensures finished product never exceeds allowable residue levels. The rigid approach costs a bit more per batch, but we have avoided every recall and rejection based on solvent issues — a return that justifies the extra oversight.
Color and taste drift in the final product also arise as ongoing issues. We found early on that even marginal changes in extraction temperature or drying time could alter final appearance and taste profile. Through regular process audits, and by running small pilot batches ahead of each main run, we can predict and correct these problems before they scale up—an approach owners of contract manufacturing plants have since adopted after visiting our facilities.
Scaling up production is its own challenge. Rutin’s sensitivity to heat and humidity at certain steps means that equipment choices, maintenance, and staff diligence weigh heavily on product quality. We invest in operator training not only in equipment running, but in raw material inspection and record keeping. Only through these layers of careful attention do the output batches stay in line with the standards that long-term clients expect from us.
The rutin market has shifted in the past decade. At one time, only herbal supplement companies asked for it, typically in small quantities. Now we supply health food, pharmaceutical, and even personal care companies—each with specific needs around labeling, documentation, and product tracking.
Greater regulatory scrutiny, particularly around origins, residual solvents, and authenticity, increases as end users demand transparency. A few years ago, most customers asked for a simple Certificate of Analysis. Now, more ask for full traceability records, including origin documentation and in-house analytical data. We anticipated this by documenting our workflow in detail and archiving all results. Our quality group regularly fields audits and site visits, as more global brands audit upstream suppliers.
Pricing pressure never goes away. Competing products from lower-cost regions push prices down, but at a hidden cost to batch-to-batch quality. We have found that our customers, after rejections or complaints from lower-cost suppliers, return for repeat orders because of the reduction in unexpected problems, product recalls, or margin lost to troubleshooting quality failures.
Formulators continue to explore new delivery systems for rutin: from encapsulated powders in sports nutrition, to skin serums and advanced wound care. Each brings fresh demands on solubility, purity, and traceability. We are now supporting teams with custom milling and pre-blends, based directly on conversations with formulators and trial runs. The line between ‘commodity extract’ and functional, application-ready ingredient grows thinner every year.
We have had to invest in R&D alongside mainline production. Application support, stability testing, and even custom sensory panels have become core to our routine, a shift that relates directly to customer demand for data and predictable performance.
Feedback tells the true story. A global beverage customer recently completed a year-long shelf test comparing their legacy flavonoid blend to our rutin NF95 in their flagship drink. They showed us data: measurable improvements to color retention at six and twelve months, and a noticeable decrease in off-taste development — tracking with our own sensory results.
A domestic pharmaceutical company reported greater tablet stability and a reduction in production rejects after switching to our rutin. Prior to the switch, their solvent screen flagged residue spikes two or three times annually, often during rush orders from bulk traders. Our in-house solvent management and closer drying control eliminated these spikes, proving that investment in process discipline pays back.
In the cosmetic sector, a partner producing calming facial serums has successfully avoided visible undissolved particles and off-color issues by relying on our closely milled, filtered grades. Field reports from their quality teams confirm fewer lot-to-lot differences.
We use this feedback cycle to loop new learning back into our own process. For instance, after receiving consistent notes about placebo bitterness in test panels, we re-examined our extraction pH and solvent flush practice; since making slight process adjustments, follow-up panels showed a measurable decrease in bitter perception.
Our hands-on experience shapes every batch of rutin that leaves our plant. Stories behind the product — raw material negotiations, process adjustments, test failures and fixes — never appear on a technical data sheet, but define how we understand and improve its role in formulations. Companies come to us for reliable supply, but stay when they see how carefully monitored, precise manufacturing translates into fewer surprises in their own production.
Through countless feedback cycles in real-world use, we have built up both technical skill and an evidence base to stand behind all claims about our product. Our approach acknowledges that no two batches — of raw material, or of finished product — turn out exactly the same, so we layer controls, documentation, and constant learning at every stage.
Rutin’s story blends plant science, equipment choice, operator training, and decades of on-the-floor troubleshooting. Anyone can ship a powder. Delivering a product that meets its promise batch after batch, supporting real business decisions and consumer trust, results from an experienced manufacturer’s commitment.