|
HS Code |
379939 |
| Chemical Name | Riboflavin Sodium Phosphate |
| Molecular Formula | C17H19N4Na2O9P |
| Molecular Weight | 488.31 g/mol |
| Appearance | Yellow to orange-yellow crystalline powder |
| Solubility In Water | Freely soluble |
| Cas Number | 130-40-5 |
| Storage Conditions | Store in a cool, dry place and keep container tightly closed |
| Melting Point | Decomposes above 240°C |
| Ph Of Solution | 6.0 - 8.0 (1% solution in water) |
| Usage | Nutritional supplement and food additive |
| Synonyms | Vitamin B2 Sodium Phosphate, Riboflavin 5’-phosphate sodium salt |
| Stability | Stable under normal conditions |
| Color | Yellow |
| Odour | Odorless |
| Einecs Number | 204-984-4 |
As an accredited Riboflavin Sodium Phosphate factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | Riboflavin Sodium Phosphate, 100g, packed in a sealed amber glass bottle with tamper-evident cap, labeled with safety and batch details. |
| Shipping | Riboflavin Sodium Phosphate should be shipped in tightly sealed containers, protected from light and moisture. It must be kept at room temperature and handled with care to avoid contamination. Transportation should comply with local regulatory guidelines, and the shipping package must be clearly labeled, especially if sent in bulk quantities for industrial use. |
| Storage | Riboflavin Sodium Phosphate should be stored in a tightly closed container, protected from light and moisture. Keep it in a cool, dry place, ideally at a temperature between 15°C and 30°C (59°F and 86°F). Avoid exposure to heat and incompatible substances. Ensure storage areas are well-ventilated and compliant with local chemical safety regulations. |
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Purity 98%: Riboflavin Sodium Phosphate with 98% purity is used in pharmaceutical formulations, where it ensures high bioavailability and consistent therapeutic outcomes. Solubility High: Riboflavin Sodium Phosphate with high solubility is used in injectable solutions, where it promotes rapid absorption and effective vitamin delivery. Stability Temperature 40°C: Riboflavin Sodium Phosphate with stability up to 40°C is used in heat-processed beverages, where it maintains vitamin potency during thermal treatments. Particle Size <50 μm: Riboflavin Sodium Phosphate with particle size less than 50 micrometers is used in nutritional powders, where it enables uniform dispersion and improved mouthfeel. Light Stability Enhanced: Riboflavin Sodium Phosphate with enhanced light stability is used in transparent liquid supplements, where it minimizes degradation under shelf lighting. pH Range 5-8: Riboflavin Sodium Phosphate effective in pH range 5 to 8 is used in oral suspensions, where it provides optimal stability and shelf-life. Moisture Content <1%: Riboflavin Sodium Phosphate with moisture content below 1% is used in tablet manufacturing, where it prevents clumping and ensures consistent tablet hardness. |
Competitive Riboflavin Sodium Phosphate prices that fit your budget—flexible terms and customized quotes for every order.
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Producing Riboflavin Sodium Phosphate has taught us plenty about the day-to-day realities in vitamin manufacturing. Every batch starts with pure riboflavin, then passes through a careful phosphorylation process so the final result is water soluble. As a direct manufacturer, we get asked about the difference this phosphate version brings compared to plain riboflavin and other derivatives. Years of quality control and third-party audits—by both domestic and overseas teams—drive our confidence in this product. The sodium salt form offers practical advantages in both nutrition and production. We choose technology that balances purity and yield for each batch, not just speed or cost. Our team adjusts for any lot-to-lot variation in starting materials or upstream fermentation output, always watching for even minor shifts in color and solubility.
Most of our output follows our RB-SP models, produced as fine powders and clarified solutions. Major food, supplement, and pharmaceutical producers use the RB-SP series for premixes, syrups, injectables, and even fortification of medical foods. Organizations with tight registration or certification requirements rely on our sodium phosphate grade because it dissolves fast and avoids typical dust and clumping issues seen with crystalline forms. We keep tight control over particle size distribution, sodium content, and phosphate balance to help our customers maintain predictable results in blending and further processing. Monthly stability testing and documentation are standard in our operation. Our own technical staff troubleshoot with partners when a formulation shift or line change needs a new batch or grade.
Straight riboflavin—Vitamin B2—has stayed important in nutrition since the 1930s. Yet, some users run into headaches with the traditional yellow powder. Basic riboflavin barely dissolves in water. That slows down beverage processing, pharmaceutical mixing, and makers of syrups or injectables. Riboflavin Sodium Phosphate fixes those headaches. As a manufacturer, we see this difference right at the point of production. Liquids produced with sodium phosphate dissolve quickly and don’t leave undispersed color or grit at the bottom of a tank. Our lab staff regularly logs better clarity metrics in water and buffer systems compared to standard riboflavin powder.
Some customers switch to riboflavin sodium phosphate when they move from tablet-based products toward fortifying dairy analogs, sports drinks, or pediatric elixirs. The sodium salt’s faster water solubility and improved chemical stability give a smoother, brighter outcome. Our clients in parenteral nutrition and injectable preparations count on its purity and low allergen risk. Production partners like working with a product that disperses without special high-speed mixers.
Most customers want to hit a nutritional target: the recommended daily intake of Vitamin B2. We supply grades for food, feed, and human pharma, each batch meeting different regulatory needs in the Americas, Europe, and Asia. Some projects focus on pediatric nutrition—think supplements and medical foods for infants or people with special medical needs. Others use riboflavin sodium phosphate in oral rehydration solutions or concentrated vitamin shots. We’ve watched big beverage brands shift to this form because it’s more consistent when making low-pH energy drinks or shelf-stable bottled formulas.
Riboflavin sodium phosphate acts as a true functional ingredient in many settings outside the lab. In beverage plants, the easily dissolved powder provides a more even color and a barely detectable taste. Technical teams use our specification sheets to integrate the product right alongside other water-soluble vitamins like ascorbic acid or niacinamide. This means brands can reduce overages and avoid the clogged filters that sometimes turn up with straight riboflavin. Our real-world QA logs show fewer tank residues and little impact on flavor, as confirmed by our food science partners. That makes the work of quality control, batching, and scaling up a lot smoother.
We run every batch through a full battery of tests—assay, purity, moisture, pH, heavy metals, and microbial content. All raw material sources meet our standardized screening formulas. We stick with automation for dosing, but humans do the final checks because even the best sensors can miss a rare impurity. Every staffer training on line, QA, or batch documentation has walked the process floor. That hands-on time keeps our output predictable.
Batch records always include retention samples for traceability. Our clients, especially those in regulated markets, come for our full trace system and batch-to-batch uniformity. Technical staff provide certificates and product histories that meet local rules, and in-house audits are routine. We work through years of experience facing different local standards—EP, USP, FCC, and others. This work gives us perspective on how regulators and large customers inspect our facility, test our water, and even audit our phosphate suppliers.
Years in chemical manufacturing show us that long-term safety and consistent output depend on more than machines. We monitor air and water emissions, follow up on waste handling, and commit to quarterly audits. Strict cleanup schedules and in-line monitoring guard against cross-contamination. Staff receive regular retraining in critical non-conformance reporting. As a producer, we know even a minor slip can result in scrapped output or lost certifications. A consistent no-contaminant record isn’t luck. It’s a lived discipline that’s built up over time, adjusted each season with actual production results and incident analyses.
On the sustainability front, we adopted water recycling and solvent minimization before local regulators required it. Every year, we make internal improvements—such as switching to closed-handling equipment and adding energy-efficient lighting across the phosphate production area. Our experience shows these moves pay off on plant safety, too: the cleaner and more organized a production line, the fewer deviations in sodium or phosphate levels across finished product lots.
Working directly with manufacturers in food, beverage, feed, and health sectors exposes us to the tough realities of commercial blending and packaging. Standard riboflavin tends to generate more dust, making workplace air monitoring harder and slowing down automated lines. Our sodium phosphate process cuts dust and stickiness, providing both worker and process safety. The product forms a stable, bright yellow powder that can be moved by auger, screw, or pneumatic systems.
For water-based formulations like ready-to-drink beverages, syrups, or injectables, Riboflavin Sodium Phosphate simply behaves better. It goes into solution quickly, so operators get a clearer batch with fewer adjustments. At the end of the batch, QC teams note far fewer filter clogs. This means less downtime and more confidence for operators under pressure to meet tight schedules. In applications such as small volume parenteral solutions, this form supports precision and safety.
The backbone of riboflavin sodium phosphate’s appeal is straight chemistry. By introducing sodium phosphate to the riboflavin backbone, the molecule takes on a negative charge at physiological pH. This change offers pronounced water solubility, turning the normally stubborn, water-repelling yellow powder into something that dissolves with much less agitation. Our data, built up from hundreds of in-plant solubility trials, support this: food and drink makers see a tenfold-plus improvement in dissolution rate compared to classic B2. Instead of settling out or requiring special dispersants, the sodium phosphate form stays mixed and bright yellow.
Our RB-SP series comes in a consistent powder with moisture content based on lot and customer spec. We’ve tuned our dryer and crystallizer units to produce a specific targeted particle size range. The sodium and phosphate levels matter for both performance and regulatory categorization. Many supplements and lotions use cheaper simple esters of riboflavin, but these forms often lag in dissolution and stability—particularly in complex beverages, parenteral solutions, or baby formulas.
Producers change their formulas more often than many think. Either for regulatory reasons, flavor changes, or to catch up to a competitor’s latest launch, they often shift formats, acidulant levels, and fortification targets. Our technical team is in the field helping these partners make the switchover to sodium phosphate B2. Customers learn that once the sodium phosphate salt is in use, operators can shorten batch time, and line managers notice less dust or clog in the machinery.
Our support often goes beyond simply recommending a grade. The relationship with our long-term buyers means we get early notice of upcoming projects or process challenges. The field team sets up test runs, reviews pilot batch data, and identifies where process parameters (like tank pH or mixing rate) impact the performance of B2. By troubleshooting right at the tank or line, we help keep projects from getting stuck in endless R&D loops.
The sodium phosphate form of riboflavin covers a wide ground—from baby food plants in Asia, to energy drink producers in Europe, and to parenteral nutrition facilities in the Americas. Our feedback loop runs continuously—batch logs get reviewed jointly between plant, QA, and customers. We’ve driven improvements based on practical observations, like optimizing spray-drying conditions at higher humidity or finetuning the in-line dosing pumps so they don’t shear sensitive vitamins during blending. Our experience as a manufacturer, not a distributor, sharpens our sense of what works and what’s just theory. It comes down to standing behind what we ship: if there’s ever a batch complaint or technical hesitation, our experts make on-site visits or walk the line in real time over video with in-plant engineers.
Our process investments mean new filtration, more robust instrumentation, and expanded in-plant pilot lines. Each change starts from observations—like cutbacks on lost product or resolved bottleneck complaints. As regulations change and customers push for new features (whether it’s an allergen-free claim or improved shelf life), our technical and sales teams close the loop between lab, floor, and the customer’s operation.
When long-term industry partners come to us, they usually have a specific goal: minimize downtime, replace problematic ingredients, or scale up a niche nutritional blend. The strongest cases involve close collaboration. Our teams dig into existing process data, share solubility checklists, and recommend feeding rates and dosing windows. We take feedback directly from workers managing industrial hoppers, QC teams pulling grab samples, and those responding to new labeling requirements. These are the details a true manufacturer values—their insights build our everyday improvements in batches and response time.
Most product developers appreciate that sodium phosphate B2 cuts complexity, especially when they juggle new launches under deadline. Our experts provide historical data and reference samples, sharing the actual results reached by dozens of other producers in energy drinks, clinical nutrition, and specialty feeds. Getting the formulation right on the first scale-up makes a stronger return for the project.
In our experience, users come back to riboflavin sodium phosphate because of the clean blending, rapid dissolution, and time-tested compatibility with other water-soluble actives. It prevents the floating or caking problems of classic riboflavin, especially in RTD and low-viscosity mixes. Our manufacturing partners often find more success with lower overages and improved end-product visual appeal. The phosphate and sodium content rarely cross interaction boundaries with other actives, making troubleshooting easier across larger production lines.
For those switching to clean-label products or fortifying foods with tight allergen controls, sodium phosphate B2 lays a cleaner foundation. We log lower reject rates due to undissolved vitamin dust or filter problems, saving both material cost and downtime. In systems sensitive to pH or requiring long hold times—like hospital nutrition or special infant formulas—our labs consistently hit stability marks. This traceability and service record comes from doing the work batch after batch, season after season.
In recent years, regulations and market trends shifted. Beverage makers aim for bright clean colors and rapidly dispersed actives. Medical food and supplement producers care about low pyrogen, low-residual allergen, and traceability. As a manufacturer, we respond with process transparency, process records, and quick turnarounds on technical questions. Our flexibility comes directly from running the entire production chain—from fermentation, phosphorylation, to drying and packing.
New requests have included even tighter particle-size control for specialized microencapsulation or slower-release dosage forms. Working closely with machinery suppliers, we’ve delivered custom packages—such as anti-static powder flows and larger pack sizes for bulk handling. Each of these tweaks reflects hundreds of production runs and joint problem-solving with partners who value vendor input and traceable outputs.
Our site team sees, every day, that the real difference in Riboflavin Sodium Phosphate isn’t just paperwork compliance or spec-sheet targets. It is production know-how: how to fine-tune crystal growth, where emissions can creep in, what to adjust when humidity spikes, how to reroute a line after a test fails. We’ve learned to trust the experience of both the lab manager and the process engineer on the floor.
Each time a customer rolls out a new formula, our technical support stays in step from small batch sampling through full-scale production. If a process or application issue turns up—unusual viscosity, new color standards, unexpected reactions with other fortification agents—our troubleshooting squad is only a call or visit away.
Industry needs evolve constantly. Over the past decade, we’ve seen the push for lower residual solvents, reduced packaging waste, and faster product rollouts. Through this, our approach to Riboflavin Sodium Phosphate has grown more adaptive. We don’t just monitor results—we improve methods in real time, sharing findings with both regulators and production staff. Investments in automation and better analytics have reduced error rates and improved overall plant output.
Our sustained commitment shows up in the year-over-year compliance, reduction of returns, and the number of new clients switching over from classic riboflavin forms. As science and regulations move forward, so do our methods, documentation, and training. Customers worldwide continue to trust riboflavin sodium phosphate for projects where solubility, predictability, and food safety matter.