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HS Code |
643422 |
| Chemical Name | Retinyl Acetate |
| Synonyms | Vitamin A Acetate |
| Molecular Formula | C22H32O2 |
| Molecular Weight | 328.49 g/mol |
| Appearance | Yellow to yellow-orange oily liquid or solid |
| Solubility | Insoluble in water, soluble in fats and oils |
| Cas Number | 127-47-9 |
| Melting Point | 57 °C (135 °F) |
| Boiling Point | Unavailable (decomposes before boiling) |
| Storage Conditions | Store in a cool, dry place, protected from light |
| Stability | Stable under recommended storage conditions |
| Main Use | Nutritional supplement (source of Vitamin A) |
| Odor | Slight, characteristic |
| Einecs Number | 204-844-2 |
As an accredited Retinyl Acetate factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | Retinyl Acetate, 500g, packaged in a sealed amber glass bottle with tamper-evident cap and chemical safety labeling. |
| Shipping | Retinyl Acetate should be shipped in tightly sealed, light-resistant containers to protect it from air, light, and moisture. It is typically transported as a non-hazardous chemical under standard temperature conditions. Ensure appropriate labeling and compliance with local regulations during transit. Handle with care to avoid exposure and contamination. |
| Storage | Retinyl Acetate should be stored in a tightly closed container, protected from light, heat, and moisture. Keep it in a cool, dry, well-ventilated area, ideally at temperatures below 25°C (77°F). Avoid exposure to strong oxidizing agents. For stability and safety, store away from sources of ignition and incompatible substances. Always label the container clearly and follow appropriate chemical storage guidelines. |
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Purity 98%: Retinyl Acetate with 98% purity is used in cosmeceutical creams, where it enhances epidermal cell turnover for improved skin texture. Molecular weight 328.5 g/mol: Retinyl Acetate at 328.5 g/mol molecular weight is used in pharmaceutical vitamin supplements, where it provides precise dosage consistency for optimal vitamin A delivery. Stability temperature 25°C: Retinyl Acetate stable at 25°C is used in nutritional fortification of dairy products, where it maintains vitamin functionality during storage. Melting point 57°C: Retinyl Acetate with a melting point of 57°C is used in compressed tablet manufacturing, where it ensures uniform dispersion and controlled release. Particle size <50 microns: Retinyl Acetate with particle size less than 50 microns is used in powder drink mixes, where it provides rapid dissolution and improved bioavailability. Solubility in oil: Retinyl Acetate with high solubility in oil is used in soft gel capsules, where it enables efficient encapsulation and extended shelf life. Assay 95% min: Retinyl Acetate with a minimum assay of 95% is used in animal feed premix, where it supports precise nutritional supplementation for livestock. Residual solvent <0.1%: Retinyl Acetate with residual solvent below 0.1% is used in injectable formulations, where it minimizes toxicity risks and ensures patient safety. |
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Working on the production floor or in the final QC lab, we see firsthand how Retinyl Acetate brings something practical yet essential to industries looking for a dependable vitamin A ingredient. We have spent years perfecting how we synthesize and purify this product, listening to what nutritionists, formulators, and end-users actually need rather than following a generic pattern. Retinyl Acetate stands out as an active, easily absorbed form of vitamin A, proven not just in technical literature but in thousands of metric tons delivered and measured for actual bioactivity batch after batch.
Retinyl Acetate, a clear or pale yellow, oil-soluble liquid or powder, has seen decades of trusted use, especially where stability and potency count. Many finished goods manufacturers prefer the acetate ester precisely because it delivers consistent vitamin A activity, holds up under harsh conditions, and blends directly into various media without extensive compatibility trials.
Vitamin A exists in nature in several forms. In chemical manufacturing, two main esters matter for commercial purposes: Retinyl Acetate and Retinyl Palmitate. We've compared them across countless tests and end-uses. Retinyl Acetate, with its straightforward synthesis from retinol and acetic acid, often gives a product with cleaner sensory qualities and easier handling at ambient and slightly elevated temperatures. Its molecular structure offers both a reliable source of retinol and a stability advantage, especially in dry powder blends.
Food fortification, animal feed, dietary supplements, and personal care industries all require vitamin A, but each sector approaches the product with a different priority—shelf-life, dispersibility, potency, and batch-to-batch reproducibility. That's where our experience makes a difference. We've learned what a premix blenders expect; we've seen how a skin care formulator reacts to small changes in texture and purity. This product gives vitamin A activity measured in international units (IU), and our process lets us standardize and guarantee the actual retinol equivalence with every shipment.
No one wants surprises in their raw material purchase. In our facility, production consistency starts with pharmaceutical- and food-grade reactants, clean-room blending, and a multiple-step purification process. Our most widely used model delivers Retinyl Acetate as a fine, free-flowing powder, stabilized with antioxidants, and protected from light and oxidation. Typical assays show retinol activity no lower than 500,000 IU per gram as dry powder, though we also offer oil-dispersed forms suited for soft gel manufacture and emulsions.
Every specification highlights the details we know matter—particle size for precise blending, antioxidant system for storage, light-reactivity levels, heavy metal residues, and residual solvents. These are not just marketing claims; we open our plant to regular third-party audits and keep a clear record of every control step, from starting material identity to the final packaged product.
In vitamin premixes for flour, cereals, and dairy replacements, Retinyl Acetate’s powder format delivers reliable dosing and resists degradation through mixing, high-shear extrusion, and shelf storage. Feed manufacturers have relied on acetate-based sources for decades, since it matches the dosing requirements in livestock and poultry diets and handles the typical pelleting temperatures better than sensitive alcohol forms.
Personal care formulators value another property. Oil solubility and mild odor make Retinyl Acetate a smart choice for vitamin-rich skin creams and lotions, especially where product feel and storage stability matter. Unlike water-soluble or free retinol, the acetate ester does not rapidly lose potency on the shelf. Chemists have worked out the difference in hydrolysis rates: palmitate is a little more lipid-friendly, but acetate outperforms it in powder mixes and under oxidative stress.
Every industry review hits the palmitate-versus-acetate question sooner or later, and we have years of production data to compare. Retinyl Palmitate, containing a longer fatty acid tail, appeals to those wanting maximal fat-solubility or specific cosmetic aesthetics. But Retinyl Acetate finds more favor where the priorities are high-purity, rapid release of vitamin A activity, and more general workhorse functionality in blends.
From our batch records and real-world feedback, Acetate grades win out for dry premixes and multi-micronutrient blends because they handle granulation processes and exposure to air, heat, or even moisture variations with fewer losses. In side-by-side storage trials, acetate-based powders held up, retaining higher IU content weeks after equivalent palmitate batches showed measurable degradation under warehouse conditions.
Taking commercial-scale extrusion as an example, workers have reported fewer cases of "burn off" of retinol potency during high-heat processing when using our stabilized acetate product. This translates to real savings, especially for fortification operations running 24/7 who face ingredient loss as direct margin leakage.
Manufacturing Retinyl Acetate at scale has shown us exactly how sensitive pure vitamin A can be to air, heat, and light. Our production techniques now incorporate controlled-atmosphere blending, immediate packaging in nitrogen-flushed bags, and custom antioxidant systems—these aren't theoretical improvements but hard-won strategies that came from real product returns and post-market audits.
We have tracked shelf-life not just in a controlled laboratory but in the hands of partners all over the world, under tropical storage, temperate warehouse, and challenging logistics. By request, we've run comparative trials showing acetate-based products keep consistent vitamin A activity for over twelve months, even without refrigeration or special handling protocols. This reliability means fewer end-of-run losses and easier inventory management for users who cannot afford last-minute raw material changes.
International standards and regulations dictate what can be claimed for vitamin A activity, contamination limits, and labeling requirements. As a manufacturer committed to food and feed safety, we ensure full compliance with all major codices. Our direct experience with audits—not just by regulators, but also by multinationals and NGOs—taught us the importance of open documentation, contaminant screening, and the need for full traceability. Many clients now want source documentation back to the individual batch of acetic acid used in synthesis, and we've designed our tracking systems to answer those needs without hesitation.
Retinyl Acetate, standard on the market for decades, still raises questions about bioavailability and consumer safety. Studies published in peer-reviewed journals confirm that it serves as an efficient precursor of retinol in human and animal metabolisms. This conversion happens reliably if the diet includes necessary enzymatic co-factors, a fact we always discuss with formulation teams. Missteps rarely stem from the chemical itself, but from misunderstanding storage, blending, or downstream application. We have trained technical support at the ready, not to push sales, but because we have witnessed how small technical tweaks prevent costly finished-goods failures.
A global vitamin A deficiency crisis only finds solutions with reliable, affordable sources of the compound—Retinyl Acetate continues to anchor governmental and NGO fortification programs in grain, oil, and milk. From our role as a bulk producer, we've been called upon to ramp up production for humanitarian efforts, and we witnessed the real effects such shipments have across regions hard-hit by micronutrient deficiency.
Some project managers tell us that switching to acetate from less stable forms directly increased the measurable vitamin A delivered to at-risk populations—less fading during warehouse storage and transit, fewer complications fitting into diverse processing lines. Our technical teams engage with premix suppliers in Africa, Asia, and Latin America, adapting specifications based on the actual constraints these partners face. It’s more than an upstream product—we see our responsibility in delivering nutrition that endures through the supply chain.
Sustainability and work safety carry just as much weight as vitamin content in our production decisions. Retinyl Acetate synthesis utilizes solvents and reagents requiring careful management. We designed our scrubber and recycling systems to minimize emissions, recover solvents, and send minimal residue to incineration. Occupational exposure monitoring in our plant helps us spot trends and improve ventilation and handling procedures year by year. We have seen how even minor lapses can affect both product quality and worker health, and each improvement in protocols stems from real experience—not just from regulatory pressure.
What sets us apart is the way we fold direct feedback into new manufacturing runs. Feed mill clients reported concerns about dust generation during micro-ingredient blending; since then, we've adjusted both the compaction pressure and carrier blend for our powder line, yielding less airborne particulate and higher machine throughput. Our environmental managers work alongside line supervisors, not as distant consultants, pairing real process know-how with regulatory best practices.
Innovation in vitamin A production isn’t about constant novelty, but about steadier performance and easier handling in real environments. Over the last decade, we've introduced incremental, quietly significant shifts—controlled crystallization for more predictable powder flow, new peroxide scavengers to lengthen shelf life, and packaging upgrades to suit harsh climates. All these changes took shape not in isolation, but out of responses to real end-user feedback and long series of plant and field trials.
We maintain an open door with research partners and universities, routinely sending representative samples for independent testing—not just for regulatory compliance, but to validate process changes and new stabilization approaches. We never chase overhyped claims or unsubstantiated shortcuts. Instead, we track data on actual vitamin A retention, wet chemistry outcomes, and interactions with evolving feed, food, and cosmetic matrices.
Raw material supply fluctuations, energy costs, and changing regulatory demands present ongoing challenges. Our team addresses these head-on, holding twice-yearly reviews of our entire supply chain—from oil seed input for retinol intermediates to final packaging. This process has helped us avoid quality lapses and keep prices stable even during industry-wide disruptions. We share forecasts on potential shortages with key users, giving them time to adjust their contracts or change delivery timing. No surprises is a core principle developed in hundreds of direct customer conversations.
Looking ahead, the industry moves toward even tighter standards for contaminants, footprint, and transparency. We see this not as a hurdle but as an opportunity—a way to keep setting the bar higher with each lot produced. Clients now look for non-GMO certified processes, vegan-grade statements, and full chain-of-custody documentation. We have prepared for these trends by integrating non-animal inputs into our process and building traceability tools directly into our ERP.
As a chemical manufacturer with decades of hands-on expertise, we know Retinyl Acetate isn’t about flashy marketing—it’s about unwavering reliability, technical flexibility, and measurable health outcomes. Our commitment to open, honest production and technical engagement, with an eye on environmental and user safety, means every batch carries a record of our experience and the voices of our partners in the field. Retinyl Acetate continues to underpin nutrition, wellness, and safe formulation in industries worldwide. Every circuit on our factory floor and every decision in our quality labs reflects the values and insights gained through years of real-world application, not theory or distant claims.