| HS Code | 340714 |
| Inci Name | Capryloyl Glycine |
| Cas Number | 14246-53-8 |
| Appearance | White to off-white powder |
| Solubility | Slightly soluble in water, soluble in alcohol |
| Odor | Characteristic, mild |
| Ph Range | 5.0 - 7.0 (1% solution) |
| Melting Point | 77-82°C |
| Molecular Formula | C10H19NO3 |
| Molecular Weight | 201.26 g/mol |
| Preservative Type | Amino acid based antimicrobial |
| Recommended Usage Level | 0.5 - 2% |
| Function | Antimicrobial agent |
| Compatibility | Compatible with a wide range of cosmetic ingredients |
| Shelf Life | 24 months |
| Storage Conditions | Store in a cool, dry place away from direct sunlight |
As an accredited SYNGUARD CAG (Capryloyl Glycine) factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | SYNGUARD CAG (Capryloyl Glycine) is packaged in a 25 kg white HDPE drum with a secure, tamper-evident seal. |
| Shipping | SYNGUARD CAG (Capryloyl Glycine) is shipped in sealed, high-density polyethylene drums or containers to ensure product integrity and prevent moisture contamination. It should be transported under cool, dry conditions, away from direct sunlight and incompatible substances. All packages are clearly labeled with handling, hazard, and storage information according to regulatory standards. |
| Storage | SYNGUARD CAG (Capryloyl Glycine) should be stored in its original, tightly sealed container, kept in a cool, dry, and well-ventilated area away from direct sunlight and sources of heat or ignition. Protect from moisture and incompatible materials. Ensure storage area is clean and complies with local regulations for chemical storage. Avoid unnecessary exposure and handle with appropriate personal protective equipment. |
SYNGUARD CAG (Capryloyl Glycine) is widely deployed in industrial markets as a specialty amino acid derivative with antimicrobial and skin-conditioning effects. As an experienced manufacturer, we support downstream users in several technical sectors by delivering consistent quality and formulation guidance. Below are major application tracks, referencing real-world process practices and compliance parameters.
Major cosmetic manufacturers use Capryloyl Glycine as an amino acid-based antimicrobial to protect formulations such as facial cleansers, shampoos, deodorants, and creams. Its ability to control microbial growth, combined with high dermal tolerance, supports claims of mildness while maintaining product integrity over shelf life. The ingredient is typically added during the cool-down stage in the emulsification process to safeguard against heat-sensitive degradation. Preserving both water-based and emulsified systems, the inclusion of Capryloyl Glycine aids formulators in reducing use of parabens and formaldehyde releasers, supporting clean-label strategies demanded by regulatory authorities and retailers.
Industry compliance standards
Typical usage ratio
Downstream process integration
Final product types
In dental care manufacturing, Capryloyl Glycine enables formulators to suppress oral microbial activity, addressing plaque control and pH stabilization in toothpaste, mouthwash, and oral sprays. Its integration helps reduce the growth of plaque-causing bacteria without altering product taste or causing mucosal irritation. Our ingredient supports dual roles: as a chelating antibacterial additive and as a mild surfactant for hygiene systems. Production lots are supplied to batch-controlled GMP facilities to ensure traceability and consistency in finished oral care products.
Industry compliance standards
Typical usage ratio
Downstream process integration
Final product types
Pharmaceutical and OTC topical manufacturers rely on Capryloyl Glycine as a co-active for controlling excess sebum and supporting skin barrier homeostasis in medicated creams, acne gels, and combination therapies. Its structure allows both mild keratolytic action and targeted antimicrobial activity, making it suitable for seborrheic skin, hyperkeratotic disorders, and formulations requiring pH balance. The raw material is processed under controlled cGMP conditions with validated documentation for regulatory dossiers and pharmacopoeial testing.
Industry compliance standards
Typical usage ratio
Downstream process integration
Final product types
In industrial hygiene and technical biocide systems, Capryloyl Glycine functions as a specialized mild antimicrobial against bacteria and yeasts in process water, specialty cleaning fluids, and non-rinse disinfectant formulations. Technical users deploy it in synergy with amphoteric and nonionic surfactants to extend antimicrobial spectrum, especially where consumer and environmental toxicity limits use of traditional biocides. The precise control of input ratio and order of batch addition ensures the stability and functionality required by contract manufacturers and institutional cleaners.
Industry compliance standards
Typical usage ratio
Downstream process integration
Final product types
Competitive SYNGUARD CAG (Capryloyl Glycine) prices that fit your budget—flexible terms and customized quotes for every order.
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Capryloyl Glycine isn’t a mystery molecule for us; it’s something we’ve produced, handled, tested, and watched users trust for decades. In our experience, the difference always comes down to consistency—real consistency, not just batch paperwork. SYNGUARD CAG has developed a reputation because it delivers. We see this every time a formulator calls back, not with a complaint, but for another drum. This raw material, chemically known as N-Octanoyl Glycine, started as a niche ingredient. Over time, it’s become a backbone for many customers in personal care, but its value isn’t limited to cosmetics. We manufacture SYNGUARD CAG using our own controlled processes, designed for true purity and quality, with full traceability. We don’t cut corners on the starting glycine or the fatty acid source; we’ve learned from years in the field that separating cosmetic-grade from commodity-level quality avoids headaches later on.
Our standard model of SYNGUARD CAG carries a typical assay of ≥98%. This is not a marketing claim—our staff have a habit of running GC and HPLC on every batch, largely because unexpected contamination or byproducts can ruin a run for our downstream users. Color index, acid value, and moisture content are all tightly controlled, and we keep our microbiological profile clean enough for leave-on skin applications, which is no small feat at scale. We usually supply the material as a white to off-white powder, which dissolves well and stores for years under standard packaging. What makes us different is that we’ve prioritized tight melting point ranges; spec drift doesn’t slide by here. Our raw material stewardship comes from working face-to-face with R&D teams who need the same product year after year; our process repeats because customer innovation shouldn’t get interrupted by ingredient surprises.
SYNGUARD CAG looks (and smells) like a small addition, but its impact is outsized, especially in tough-to-stabilize preservative systems. The beauty of Capryloyl Glycine is its dual functionality: we see clients use it as both a skin conditioning agent and a mild antimicrobial, especially for those personal care lines where parabens and isothiazolinones are out of the question. This amino acid-fatty acid conjugate has an amphiphilic nature that lets it slot into both water-based and emulsified systems. We see evidence of its bioactivity against microbes in proper use concentrations (typically 0.5%-2.0%), and we’re not talking about obscure lab tests—customers run panel trials and come back with real-world data.
People discuss “synergy with preservatives” a lot, but in practice, it means fewer headaches keeping products stable given the movement toward natural and non-traditional conservation systems. SYNGUARD CAG plays well with glycols, polyols, and most non-ionic surfactants, which is why cleansing, lotion, and serum formulators continually reach for it to hit both the sensorial and microbiological targets. Unlike traditional glycine derivatives, Capryloyl Glycine helps maintain the delicate balance required for skin comfort. Instead of leaning solely on alcohols that dry or harsh surfactants that strip, users report improved after-feel at even low dosages.
There’s a lot of Capryloyl Glycine out there, but production method and quality control make a world of difference. Our SYNGUARD CAG comes out with low residual solvents and next to no colored byproducts, so you won’t notice discoloration sneaking into clear gels or lotions over time. Some versions we see on the market use recycled fatty acid feeds or poorly refined glycine—the result is a spike in yellowing, odor, or just unpredictable performance. We’ve fielded questions from customers burned by cheap alternatives that separate, foam, or contribute to off-notes under stress conditions.
What distinguishes SYNGUARD CAG is repeatability. Every step in our synthesis runs under strict controls; we don’t leave the final purification to chance, nor do we ignore subtle variations that accumulate in large lots. We go beyond the certificate of analysis by comparing activity with standardized challenge tests in typical cosmetic bases. If a customer can’t get the same performance profile after reordering, then the product isn’t doing its job. Our in-house testing captures stability under realistic storage: temperature cycling, light exposure, and mechanical agitation. Keeping the raw material “clean” in this context isn’t just a promise—it’s the result of routine, unglamorous work in the lab and on the floor.
Through years in the field, we’ve seen SYNGUARD CAG wound up in varied applications, far beyond face creams and cleansers. It makes sense: antimicrobial activity, sebum regulation, and skin sensorial benefits attract formulators looking for a single ingredient that covers multiple bases. Some clients developed anti-dandruff systems using Capryloyl Glycine as a milder alternative to zinc pyrithione or climbazole, while others focused on sensitive skin lines for children and adults avoiding preservatives with allergenic potential.
SYNGUARD CAG also plays a strong role in controlling malodor in deodorant products, thanks to its ability to modulate the skin’s microbiome. Deodorant launches in Asia caught onto this trend years back, and now global customers reach out for guidance to replace triclosan or aluminum salts without losing product effectiveness. The practical advantage comes when trials show SYNGUARD CAG holding up against odor, even in high-humidity environments where other “green” antimicrobials struggle.
Working directly with R&D teams gives us early insight into challenging formulation problems. For example, some wanted high stability in sulfate-free facial cleansers without a tacky or tight after-feel. SYNGUARD CAG slotted in perfectly, not just for its tolerability but for its effect on sensory properties even at low loadings. A number of bar soap makers value it for its compatibility with traditional and synthetic surfactant bases, without causing intractable clouding or instability.
SYNGUARD CAG doesn’t get produced like commodity surfactants or additives. From raw material sourcing to reactor setup, our process gives us tighter control over purity and batch-to-batch consistency. Competitor materials sometimes focus on price optimization at the cost of quality; we’ve learned firsthand that formulators dealing with “low-cost” Capryloyl Glycine regularly face headaches down the line, especially with color drift, odor issues, solubility mismatches, and regulatory inconsistencies.
Manufacturers using Capryloyl Glycine from multi-purpose chemical plants suffer with higher batch variability—often the result of trying to make too many ingredients on the same lines, without deep cleanout or robust quality checks. Our site runs dedicated lines for SYNGUARD CAG, with continuous monitoring for off-spec readings. Years of feedback proved to us that skipping purification shortcuts pays off with customer retention and fewer recalls or complaints.
We’re frequently asked about cost difference between “standard” and “premium” Capryloyl Glycine. The reality is, cutting corners at the production level rarely saves money in the long term. Failed stability studies, lost time from reformulation, and label recalls from off-odor or skin complaints add up. As a manufacturer, we believe that true value means supplying a stable, trusted material that does the same job every shipment, regardless of external cost pressures.
We run frequent technical workshops with downstream partners, either at our site or theirs. Seeing a formulation challenge firsthand always beats a chain of emails or formal reports. Sometimes the solution isn’t to just tweak the usage level of SYNGUARD CAG; it might involve adjusting pH or switching out an incompatible co-preservative. These are the real-life adjustments that separate a theoretical formulation from a best-selling product.
For skin-friendly preservation, the pressure comes from both regulatory harmonization and consumer demand. We’ve guided clients through the regulatory maze for global compliance, with actual certificates and supporting analytical data, not just boilerplate claims. In every region, ingredient watchlists shift from year to year: willing suppliers ensure SYNGUARD CAG is validated for restricted lists, allergens, and sensitive skin—this cuts down on last-minute reformulation and regulatory risk.
We hold ourselves responsible for every drum and carton that leaves our facilities. Our focus reaches from environmental footprint in processing (where we’ve driven various internal programs to reclaim solvents and reduce water consumption) to local sourcing of starting materials as much as feasible. Our site has won recognition for safe work practices and emissions control. This isn’t about claiming “natural” or “eco-aware” status—it comes from years watching environmental shortcuts catch up with less careful producers. We back every claim with analytical data, compliance verification, and supply chain transparency, because our customers demand it, and so does our team.
SYNGUARD CAG’s solid-state physical form matters for easy handling—dusting, hygroscopicity control, and flow characteristics are often overlooked. We field routine questions about solubility, pH range for best performance, and compatibility with exotic actives. With direct line to manufacturing, we offer practical technical notes and respond quickly to inquiries stemming from real on-floor situations, not just theoretical concerns. Adjusting the raw material mean particle size or granularity for customer processes is a refinement we routinely apply for those needing specific delivery or dissolution profiles.
We keep close documentation on traceable batches. Batch records, analytical profiles, and in-use data are always accessible; this has saved more than one customer’s project when tracking down a formulation hiccup or supporting a regulatory submission. These records are mined from hundreds of batches over years, providing the industry evidence for claims of repeatable performance and long-term utility beyond just the next product launch.
Producing Capryloyl Glycine isn’t plug-and-play chemistry. Over the years, we’ve encountered plenty of hiccups: temperature sensitivity in coupling reactions, shifts in crude raw material purity, even rare contamination events. Addressing these is never glamorous. It’s about daily measurement, practical root cause analysis, and refusing to ignore out-of-spec signals, even under production pressure. Small changes in reactor temperature, pH drift, or even minor shifts in packaging moisture content show up downstream unless controlled, and that’s what sets a good producer apart from those only chasing volume.
Supply chain disruption isn’t theoretical to us. From global shortages of high-purity glycine during certain years to logistical snags with imported octanoic acid, we’ve learned not to rely on single suppliers or just-in-time inventory. Dual or triple sourcing, buffer stocks, and long-term supplier partnerships save us (and our clients) from “out of stock” scenarios that can freeze an entire product launch. Smoothing out these practical issues is part of why we’ve been chosen by brands launching into new regions or with tough compliance needs.
Demand for preservative alternatives with mild skin profiles continues to grow, and we see SYNGUARD CAG leading this trend. Everything from scalp care to intimate wash lines now looks toward Capryloyl Glycine as a foundation for skin barrier protection and microflora control. Our in-house teams are actively trialing advanced grades for even higher purity or customized crystal forms to aid new delivery concepts in topical and rinse-off care.
We also view customer education as key. Not every laboratory is familiar with best practices on solubilization or compounding Capryloyl Glycine with difficult actives. By offering real-world technical support—based on hundreds of scaled-up batches rather than just theory—we help our partners launch successful products faster and resolve formulation setbacks without endless trial and error. This hands-on approach has built longstanding relationships with key innovation teams worldwide, from major brands to indie formulators ready to take on the big players.
We’ve watched major launches take shape using SYNGUARD CAG as the backbone for “free-from” claims popular in global personal care. A European client facing regulatory bans on both formaldehyde releasers and MI/MC blends replaced their entire anti-microbial system with Capryloyl Glycine and a glyceryl caprylate blend—results exceeded panel tolerability and shelf-life expectations. Feedback came in rapid reorders, not just positive review write-ups.
Another customer, a startup in North America, wanted to create an acne-prone skincare line without pharmaceuticals or high levels of alcohol—our team guided them through inclusion at levels that stopped bacterial overgrowth while softening the base and reducing the dryness so common with standard anti-acne actives. Their clinical results backed up what we’d seen in our own tests, and the project scaled up from pilot to commercial run with the same ingredient batch each time.
Our daily work in manufacturing SYNGUARD CAG centers on delivering more than just an INCI number. We back up our quality with data, batch records, direct technical support, and years of experience navigating shifting formulator demands, regulatory standards, and real-world production challenges. Consistency, traceability, a hands-on approach to troubleshooting, and unyielding focus on responsible practices make us a trusted partner in Capryloyl Glycine. For us, the true measure of success arrives in repeat orders, customer loyalty, and the quiet confidence that comes from standing behind every shipment—batch after batch, year over year.