|
HS Code |
521136 |
| Name | Retinal |
| Chemical Formula | C20H28O |
| Molecular Weight | 284.44 g/mol |
| Iupac Name | 3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenal |
| Appearance | Yellow-orange solid or oil |
| Solubility | Insoluble in water, soluble in organic solvents |
| Melting Point | 61–65 °C |
| Function | Visual pigment precursor (in rhodopsin) |
| Synonyms | Vitamin A aldehyde, Retinene, Retinaldehyde |
| Source | Derived from vitamin A (retinol) |
As an accredited Retinal factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | Retinal is supplied in a 1-gram amber glass vial, tightly sealed, with a tamper-evident cap, and labeled for light sensitivity. |
| Shipping | Retinal is shipped in tightly sealed, light-resistant containers under inert gas, typically at cold temperatures (2–8°C) to prevent degradation. Packaging complies with regulations for hazardous chemicals due to its sensitivity and potential health effects. Proper labeling and documentation are included to ensure safe handling and transport. |
| Storage | Retinal should be stored in a tightly sealed, light-resistant container under an inert atmosphere, such as nitrogen or argon, to prevent oxidation and degradation. It should be kept at low temperatures, preferably at -20°C or lower. The storage area must be free from excessive moisture, heat, and direct sunlight to maintain the stability and purity of the compound. |
|
Purity 98%: Retinal with 98% purity is used in dermatological formulations, where it enhances skin cell turnover and reduces visible signs of aging. Molecular weight 284.43 g/mol: Retinal with a molecular weight of 284.43 g/mol is utilized in ophthalmic research, where it supports precise molecular interaction studies. Melting point 63°C: Retinal with a melting point of 63°C is applied in photoreceptor regeneration studies, where it provides stable solid-state applications. Particle size < 5 μm: Retinal with particle size less than 5 μm is incorporated into topical nanoemulsions, where it allows for improved skin penetration and uniform distribution. Stability temperature up to 25°C: Retinal with stability temperature up to 25°C is deployed in cosmeceutical products, where it maintains bioactivity during storage and formulation. Solubility in ethanol 50 mg/mL: Retinal with solubility in ethanol at 50 mg/mL is used in lipid-based delivery systems, where it achieves efficient encapsulation and controlled release. UV absorbance at 380 nm: Retinal demonstrating UV absorbance at 380 nm is implemented in photobiology assays, where it accurately activates light-sensitive proteins. Trans-isomer content ≥ 95%: Retinal with trans-isomer content of at least 95% is selected for vision restoration therapies, where it ensures reliable and consistent biological response. |
Competitive Retinal prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please contact us at +8615365186327 or mail to admin@ascent-chem.com.
We will respond to you as soon as possible.
Tel: +8615365186327
Email: admin@ascent-chem.com
Flexible payment, competitive price, premium service - Inquire now!
Every batch of Retinal we produce starts with a straightforward principle: quality ingredients support reliable research, effective medicine, and optimized manufacturing. Retinal, with the aldehyde form of vitamin A, stands apart from both retinol and retinoic acid in terms of stability, reactivity, and versatility. Over years of production, we have come to recognize the precise needs of customers who look beyond basic vitamin A derivatives. Experience in synthesis and purification gives us the confidence to describe Retinal not just as a yellow crystalline solid with a defined molecular structure, but as an ingredient that solves actual laboratory and commercial hurdles.
Raw material variability, temperature sensitivity, and air stability remain critical pain points for those handling Retinal. We address these factors from upstream process controls throughout storage and shipment. Our standardized model features all-trans-retinal with defined impurity profiles. Years of feedback from pharmaceutical and research partners steered us toward tighter moisture thresholds and packaging designed to minimize isomerization. The inherent light sensitivity of Retinal motivates our team to package every shipment in amber glass under nitrogen, which slows oxidation and preserves assay value. Many customers shared stories about past suppliers whose variable supply created batch-to-batch headaches. By anchoring our process with in-line analytical verification, including high-resolution chromatography, we safeguard both the appearance and the chemical integrity of each lot.
Applications range from vision research and photoreceptor biochemistry to clinical formulation, cosmetics, animal nutrition, and flavor chemistry. In the lab, Retinal proves indispensable for opsin-reconstitution assays and deepening understanding of the visual cycle. Retinal’s presence in rod photoreceptors as a chromophore enables the conversion of light into chemical signals. This process underpins not only vision studies, but also models of oxidative degeneration and cell health that guide drug discovery. In the skin care sector, professionals turn to Retinal for faster dermal turnover compared to retinol, and lower irritation compared to retinoic acid. Our steady supply of high-purity Retinal has supported new topical product launches and advanced academic studies into retinoid transport and metabolism.
Plenty of clients ask why Retinal deserves attention over retinol or retinoic acid. The answer comes down to activity, transformation, and context. Retinol, often called vitamin A alcohol, stores well and features in nutritional supplements, but in biological systems, it needs oxidation to produce Retinal. Retinal, once present, serves directly in light-sensitive proteins in the eye or as an intermediate on the path to retinoic acid. Retinoic acid marks the endpoint with powerful gene regulatory effects, but proves less stable, more irritating, and strictly controlled in many applications. Retinal lands in the sweet spot: it adds bioactivity but balances reactivity and shelf-life. Over the years, chemists in our network reported greater versatility using Retinal for both chemical synthesis and controlled release products. The aldehyde function expands the toolbox for forming Schiff bases and studying protein binding — a feature not offered by retinol.
Direct experience with Retinal has taught us where typical headaches start. Storage at low temperature, under dry and inert conditions, remains non-negotiable for product longevity. Glassware carrying trace acids or bases often destroys the aldehyde quickly, so we coach careful cleaning and recommend single-use pipettes for high-precision work. The scent of freshly synthesized Retinal, slightly floral and sweet, signals a successful run — and any deviation hints at trouble. Operators who learn to trust their senses along with analytical records make fewer mistakes and save more product over the long term. Every so often, a customer consults us about solubility. Retinal dissolves well in organic solvents like ethanol and DMSO, but pre-warming and vials free of water promote a faster, clearer solution. Once in solution, shielding from light and rapid use protect potency.
Years of batch verification affirm our Retinal’s melting range sits squarely between 61 and 64°C. Packing density and free-flow qualities mean easy weighing, without unnecessary clumping. Over multiple audits, our purity profiling lands above 98% (HPLC), a value directly checked against fresh analytical standards. The storage under -20°C with desiccants extends usable shelf life for months without significant loss of potency or yellowness. We encourage customers to break larger stocks into single-use aliquots to prevent moisture ingress on repeated opening. From pilot plant to ton-scale, the experience has shown clear labels, lot-specific certificates, and strict cold-chain tracking really matter if you want to avoid the shocks and questions that come with lower quality suppliers.
Retinal connects tightly with light and vision, while retinol supports nutritional value and retinoic acid triggers DNA-level responses. Each brings something unique, but the chemistry shifts in subtle, important ways. Our team has compared stability profiles across these molecules over the years; Retinal shows greater durability in dry, sealed environments, but more sensitivity to open air than retinol. Unlike retinoic acid, Retinal stands up better to repeated cycles of opening and closing vials in research routines. Solubility tips come straight from our lab notes: Retinal dissolves faster in absolute ethanol than retinol, and transient cloudiness vanishes with mild heating and agitation. Customers blending pharmaceuticals or testing new product formats often notice batch uniformity holds true with our material, setting it apart from sources that cut corners or skip advanced filtration.
Supply interruptions and purity drift have plagued users of Retinal sourced through fragmented distribution channels. Unlike remote brokers, we built redundancy into every step: monitored storage, real-time stock status, dual-site reserve batches, and steady shipping relationships. Orders don’t fall through cracks, and technical queries reach chemists who have touched the real product, not just paperwork. Our advice on using and storing Retinal draws on years rescuing studies derailed by degraded material. Questions about synthesis intermediates, side reactions, or custom lots land on chemists’ desks, not marketers’. This hands-on support prevents costly rework and keeps even the most demanding projects on schedule.
Rarely does one grade suit all needs. Researchers focused on crystalline structure for mechanistic studies have different requirements from manufacturers blending stable emulsions. Recognizing this, we respond with custom crystallization, solvent matching, and concentration pre-packs, reducing prep work for end users. On occasion, a client will ask for isotopically labeled material, or fractions enriched in specific isomers. Our plant adapts processes, always documenting yields and purity step by step, so users know exactly what they’re working with. New production advances in microencapsulation and solid dispersions offer longer shelf life in finished dosage forms, and our ongoing trials promise better handling characteristics in the near future.
University projects on retinal regeneration lean heavily on a trustworthy Retinal source. Over the last decade, we’ve supplied numerous grants where the fate of multimillion-dollar research quickly turns on whether Retinal behaves exactly as expected. For instance, antibodies generated against retinal-protein conjugates reveal subtle discrepancies when sourced from inconsistent Retinal supplies. These lessons show seasoned suppliers become a real partner in academic progress. The impact stretches beyond the university: accurate animal models receive true all-trans-Retinal, supporting discoveries that feed into drug pipelines and clinical trials. This cycle depends on open communication, reliable documentation, and willingness to troubleshoot either from the production floor or in the customer’s lab.
Regulatory frameworks around Retinal differ by end use and market. Pharmaceutical-grade Retinal requires adherence to purity and residual solvent limits. Our facilities designed batch records to exceed current regulatory demands, using up-to-date reference standards and validated methods for each lot. Staff oversee contamination control and track traceability from raw input to finished product. This vigilance stems from learning where accidents start and how downstream users get affected by seemingly minor missteps upstream. For those developing consumer products — be they supplements, pet nutrition, or cosmetics — our compliance team directly supports claims substantiation and recalls best practices for storage, labeling, and safe handling.
Our exposure to industrial buyers and research scientists clarifies the hurdles faced during product development. Clients entering the ophthalmic or dermatological market always weigh cost versus quality but often underestimate loss due to batch variability or product failure. Industry veterans who value robust supplier relationships see measurable gains in processing yields and market launches. Routine site visits allow partners to audit, review our records, and see the culture that puts quality ahead of pushy marketing. Whenever a user identifies bottlenecks, be it with blending, dissolution, or regulatory paperwork, our response draws from experience, not abstract procedures.
Chemistry does not stand still. New discoveries about Retinal, from its antioxidant role to novel delivery systems, push us to refine manufacturing and testing. Regular interaction with formulation chemists, process engineers, and safety officers shapes our training and process updates. Feedback from downstream quality checks often leads to procedural tweaks—tighter humidity control here, different solvent purification there—each with measurable improvements in final product behavior. These adaptations go beyond regulatory minimums and address overlooked pain points, smoothing the way for users aiming for faster approvals and more reliable results. The commitment isn’t static: it grows with each technical challenge we tackle alongside our customers.
Everything about Retinal calls for careful handling: the yellow tint deepens in light; off-odors spell trouble; a single drop of condensation degrades product fast. Every customer logistics team needs to act fast at receipt, moving shipments to cold storage without delay. We gear training and instructions for real-world teams, not just laboratory experts. For research, aliquoting under nitrogen and using septum-sealed vials preserves Retinal for weeks. Manufacturing clients automate handling within glove boxes. Over time, even subtle changes — higher fill volumes in smaller bottles, desiccant upgrades, slightly thicker glass — have reduced customer returns and boosted performance downstream.
As Retinal demand grows in medical, cosmetic, and animal markets, the old model of commodity-like chemical sales falls short. Customers demand more than basic purity; they request batch reproducibility, customization, technical guidance, and responsible manufacturing. We control environmental releases, invest in closed-loop solvent recapture, and sharpen energy use benchmarking. That focus keeps us relevant with sustainability benchmarks adopted by larger markets and enables longtime staff to feel pride in both what they make and how they make it. Partnerships with local recyclers and academic consortia further minimize waste and encourage smart resource planning all the way down the value chain.
Bringing Retinal from synthesis to customer shelf takes more than chemistry textbooks and lab coats. Our journey navigates failed batches, customer emergencies, factory upgrades, and late-night troubleshooting calls. Every kilogram of Retinal we ship comes with the relief of knowing its origin, composition, and shipment chain. Trusted relationships are forged in these routines, with newcomers often relying on our institutional memory and broad client experience to avoid common missteps. Real value for customers arises from this shared know-how — insights about process scale-up, translation from benchtop to pilot plant, and staying ahead of shifting technical and regulatory demands.
Looking back, the evolution of Retinal production at our facility reflects both the rich complexity of this molecule and the collaborative efforts it inspires. Customers expect more than raw supply; they expect problem-solving, transparency, and adaptability. Every advance—from glass packaging improvements to more robust analytical protocols—sprang out of real needs voiced by expert users. The power of Retinal as a research and commercial tool owes everything to not only what goes into each bottle, but also to the ways this ingredient connects experts across research, medicine, and industry. Each successful collaboration builds a stronger chain, and each failure—painful as it may be—offers lessons that refine our process for the customers who depend on us.