Products

Polyoxyethylene 35 Castor Oil

    • Product Name: Polyoxyethylene 35 Castor Oil
    • Alias: Cremophor EL
    • Einecs: 500-018-3
    • Mininmum Order: 1 g
    • Factroy Site: Yudu County, Ganzhou, Jiangxi, China
    • Price Inquiry: admin@ascent-chem.com
    • Manufacturer: Ascent Petrochem Holdings Co., Limited
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    Specifications
    HS Code 863351
    Chemical Name Polyoxyethylene 35 Castor Oil
    Synonyms Cremophor EL, PEG-35 Castor Oil, Polyoxyl 35 Castor Oil
    Appearance Clear to pale yellow viscous liquid
    Odor Faint characteristic odor
    Solubility In Water Soluble
    Molecular Formula Variable (based on castor oil and ~35 ethylene oxide units)
    Cas Number 61791-12-6
    Hlb Value 12-14
    Ph Of 5 Percent Solution 6.0 - 8.0
    Density Approximately 1.05 g/cm³ at 25°C
    Viscosity 400–800 mPa·s at 25°C
    Primary Use Nonionic surfactant and solubilizer

    As an accredited Polyoxyethylene 35 Castor Oil factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing The packaging for Polyoxyethylene 35 Castor Oil contains 5 liters in a high-density polyethylene drum with a secure screw cap closure.
    Shipping Polyoxyethylene 35 Castor Oil is typically shipped in tightly sealed, corrosion-resistant drums or containers to prevent contamination and moisture absorption. During transit, it should be protected from extreme temperatures and direct sunlight. Ensure containers are clearly labeled and handled according to chemical transport regulations for non-hazardous materials.
    Storage Polyoxyethylene 35 Castor Oil should be stored in a tightly closed container, away from moisture, heat, and direct sunlight. Keep it in a cool, dry, well-ventilated area, ideally at room temperature. Avoid contact with strong oxidizing agents. Ensure containers are clearly labeled to prevent contamination and accidental misuse. Always follow local regulations and supplier guidelines for safe storage.
    Application of Polyoxyethylene 35 Castor Oil
    Purity 99%: Polyoxyethylene 35 Castor Oil with purity 99% is used in injectable pharmaceutical formulations, where it enhances drug solubilization and bioavailability. Viscosity 600-800 cP: Polyoxyethylene 35 Castor Oil with viscosity 600-800 cP is used in ophthalmic solutions, where it provides optimal emulsification and consistent active ingredient dispersion. Molecular Weight 2500-2700 Da: Polyoxyethylene 35 Castor Oil with molecular weight 2500-2700 Da is used in cosmetic emulsions, where it improves stability and skin absorption of active compounds. Cloud Point 32°C: Polyoxyethylene 35 Castor Oil with a cloud point of 32°C is used in parenteral nutrition, where it maintains clarity and prevents phase separation under physiological conditions. Hydrophilic-Lipophilic Balance (HLB) 15: Polyoxyethylene 35 Castor Oil with HLB 15 is used in oral suspension formulations, where it ensures homogeneous distribution and prevents sedimentation of active ingredients. Stability Temperature 40°C: Polyoxyethylene 35 Castor Oil with stability at 40°C is used in vaccine adjuvant systems, where it preserves emulsion integrity during storage and transport. Non-Ionic Grade: Polyoxyethylene 35 Castor Oil with non-ionic grade specification is used in dialysis fluids, where it minimizes protein binding and prevents precipitation of solutes.
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    Certification & Compliance
    More Introduction

    Polyoxyethylene 35 Castor Oil: A Closer Look from the Manufacturing Floor

    What Makes Polyoxyethylene 35 Castor Oil Special?

    Decades of daily work with ethoxylation processes offer a direct perspective on how Polyoxyethylene 35 Castor Oil (also known in some markets as PEG 35 Castor Oil) built its reputation as a reliable solubilizer and emulsifier. Delivering consistent product quality is no accident. Our approach always begins at the raw material stage, with high-purity castor oil and carefully controlled ethylene oxide addition—balancing safety with chemical precision.

    Most batches destined for the pharmaceutical, cosmetic, and food-processing sectors barely leave our plant until we run through a full spectroscopic profile. There’s a reason customers request Polyoxyethylene 35 Castor Oil by model: not all castor oil ethoxylates behave the same, even when they carry similar names. A key difference comes down to the distribution of ethylene oxide units. With an average of 35, this model hits a sweet spot for both HLB (hydrophilic-lipophilic balance) and compatibility in a range of formulations.

    Everyday Experience in Manufacturing and Use

    Operators on our lines understand that batch-to-batch consistency can’t be taken for granted. Polyoxyethylene 35 Castor Oil requires careful monitoring—temperature, pressure, catalyst choice, and reaction time all play important roles. A slight deviation in ethoxylation conditions can throw off the HLB and lead to separation in finished products. Our teams keep records for every lot, knowing that a minor shift in color or clarity signals when to review either raw materials or process conditions.

    On the receiving end, customers use the material for solubilizing poorly water-soluble drugs, blending with non-ionic surfactants in topical creams, and stabilizing emulsions in liquid personal care products. Injectable formulations, for example, demand Polyoxyethylene 35 Castor Oil that passes strict quality controls—low residual ethylene oxide and minimal peroxide content. We run GC and peroxide value tests on every lot intended for parenteral use.

    Staff regularly interact with buyers from global pharmaceutical companies, some wanting a tweaked HLB for special actives, others interested in minimizing degradation products over time. Most end users appreciate the ease of cold blending Polyoxyethylene 35 Castor Oil into aqueous or hydroalcoholic bases—a function of its free-flowing, pale-yellow liquid form at room temperature. This performance comes from close attention to molecular weight distribution during the reaction, which we control by varying ethylene oxide feed rates and applying rigorous distillation.

    Differences from Other Castor Oil Ethoxylates

    Many newcomers assume all PEG Castor Oils offer similar properties, yet their performance diverges sharply, depending on the degree of ethoxylation. For instance, Polyoxyethylene 35 Castor Oil bridges the gap between lower-polymer grades (like PEG 20 Castor Oil) and heavier molecules with 40 or more EO units. More ethoxylation moves the HLB upward and usually increases water solubility, but at a cost to viscosity and skin feel. With 35 units, we balance these traits: you get a product viscous enough for stability but fluid enough to mix without heavy warming.

    Unlike standard surfactants like PEG-40 Hydrogenated Castor Oil, which trades some hydrophobic sites for harder structure, Polyoxyethylene 35 Castor Oil maintains flexibility both chemically and physically. Hydrogenated versions resist oxidation a bit better but often lose some emollient feel or cause instability in ethanol-rich systems. Formulators working with delicate actives—especially in biologic drugs or sensitive dermal products—often need our non-hydrogenated grade to maintain both function and compatibility with actives and excipients.

    Our experience shows end users often struggle with “off-the-shelf” surfactants that look similar on paper. Some competitors chase volume and relax quality cutoffs; those products may not pass the more exacting requirements of injectables or food-contact applications. We keep contaminants, peroxide values, and residual free PEG within defined limits, monitored batch by batch. Downstream, this translates to fewer formulation failures and less requalification work.

    Meeting the Expectations of Sensitive Applications

    Discussions with injectable drug manufacturers highlight just how vital purity and consistency remain. Polyoxyethylene 35 Castor Oil appears in formulations for drugs like cyclosporine or certain chemotherapy agents, where minor changes in surfactant composition can mean big differences in drug release or stability. We keep informed about evolving pharmacopoeial standards and check new guidance on allowed impurities, especially for residual ethylene oxide or dioxane.

    Working with regulators and direct feedback from users, we have converted some of our reaction systems to minimize formation of known process impurities—using inert gas blanketing, keeping reaction temperature controlled within low tolerances, and selecting food-grade catalysts wherever possible. Safety data gets shared in full with customers using the excipient in parenteral drugs, and we retain long-term samples of every lot for traceability.

    A downstream chemist recently shared their challenge with a “generic” castor oil ethoxylate that caused opacity in a clear solution. A quick survey by our analytical group found the difference: that batch ran with lower EO content, leading to incomplete emulsification. Problems like these drive home why customers keep asking about molecular weight, HLB, and contaminant profile. Our job calls for more than just making the material; ongoing support and troubleshooting build long-term trust.

    Polyoxyethylene 35 Castor Oil in Cosmetic and Food Use

    Manufacturing for the cosmetic markets brings different challenges. Many skin creams blend Polyoxyethylene 35 Castor Oil with fatty alcohols, waxes, or plant oils. Here, control over viscosity, poise in high electrolyte environments, and blandness in color or odor matter just as much as technical data. Our plant teams rewashed product tanks to strict standards, preventing flavor or odor carryover, as even the slightest trace can alter a high-end fragrance or lotion.

    Food-contact applications, while using similar specifications to cosmetic grades, subject us to special food safety audits. Polyoxyethylene 35 Castor Oil appears as a solubilizer for flavors and colorants, especially in beverages or clear candies, due to its ability to dissolve both hydrophobic and hydrophilic ingredients. Every season around harvest, we’ve needed to recalibrate filtration and QC plans, since raw castor oil sometimes varies slightly with crop changes. History shows that continuous supplier partnerships keep ingredient quality high and adjust for natural variation, which ultimately keeps complaints—and out-of-specification lots—down.

    Regulatory Landscape and Safety

    Over years, safety concerns regarding castor oil derivatives pop up, often related to potential for allergic reactions or formation of process byproducts. Our response always roots in transparency and shared documentation. Polyoxyethylene 35 Castor Oil has a long record of use in drug and food applications, yet regulators frequently update impurity cutoffs and react to new toxicological research. Our R&D team tracks monograph changes from the USP, EP, and JP, and we submit preemptive data packages whenever a potential issue gets flagged.

    Some buyers—especially in medical device and pediatric care—request extra documentation, with traceability stretching back to castor bean harvest and transportation storage tanks. This involves regular supplier audits, verification of allergen controls, and full traceability records for all reactants. Experience shows that close partnerships with downstream users lead to product improvements, such as lower allowable peroxide and heavy metal levels, revised clarification steps during filtration, and switching to cleaner packaging materials.

    Tackling Environmental and Sustainability Concerns

    From the factory perspective, discussions about sustainability go beyond the label. Castor oil starts as a renewable resource—it grows in arid conditions with lower pesticide and fertilizer demands than many other oilseed crops. We have worked with agricultural cooperatives aiming to minimize land-use change and protect local biodiversity. Certification tracking, for those customers who demand “green chemistry” credentials, turns from a bureaucratic step into a genuine operational priority.

    Our engineering team at the plant continues to seek ways to lower our water and energy use in ethoxylation: closed systems, heat integration, and solvent-free processes have already cut our environmental footprint. Ethylene oxide, a key input, draws attention for both worker safety and its role as a greenhouse gas precursor. We contain emissions at every reactive step, employ advanced scrubbers, and test air—and water—around our plants to ensure releases stay below national targets.

    Waste minimization plays directly into our bottom line. Our mother liquor from washing and purification gets recycled or incinerated according to local rules, and every year we look for new ways to reclaim value or convert byproducts. Several years ago, we rolled out a supplier code of conduct to prevent raw material suppliers from using land linked to uncontrolled deforestation.

    Ongoing Product Improvements—A Manufacturer’s Approach

    Real-world production never stands still. Field reports from customers sometimes flag foaming in certain beverage mixes or haze in prototype injectables. We treat every out-of-spec report as a chance to improve—adapting catalyst combinations, switching to newly available filtration aids, or adjusting end-point monitors for a tighter EO distribution curve. One example: for odor-sensitive fragrances, we recently implemented double-flash stripping to remove trace off-odors, with results confirmed by panel testing as well as GC/MS analysis.

    In meetings with global clients, technical questions often steer the conversation far beyond routine paperwork. People want to know about microbials, about rare allergen signals, about long-term trace impurity stability, and about potential supply shocks. To answer these, we keep technical staff available for live video walk-throughs of production areas, demonstration runs, or collaborative trouble-shooting. This transparency, rather than endless certificates, gives buyers the confidence needed to use Polyoxyethylene 35 Castor Oil in high-value applications.

    Analytical Tools and Quality Control in the Factory

    Inside the plant, day-to-day work depends as much on stainless steel as on sharp analytical minds. FTIR and NMR support checks on the ethoxylation degree. GC monitors for critical short-chain residues and byproducts. We load each batch onto HPLC runs to screen for oligomer distribution. Final products get visual checks, and technicians flag any difference from the reference standards created using blind-coded samples.

    Working with food and drug authorities means documenting every last data point: raw inputs, process parameters, in-process tests, post-filtration sampling, and stability monitoring. Years of tight record-keeping mean we can backtrack any unexpected field report to a specific reactor cycle or a single raw material lot. Traceability stops mistakes from turning into supply chain problems.

    Challenges That Shape Polyoxyethylene 35 Castor Oil Production

    Maintaining uninterrupted production lines takes steady attention to supply chain risks. Ethylene oxide sometimes faces regional shortages or price spikes; high-quality castor oil needs reliable partnerships in sourcing countries. Our procurement managers coordinate with logistics, technical, and QA teams to buffer inventory just enough to prevent shortages but stay lean enough for cost control.

    Contamination risk increases during periods of high demand, especially during pharmaceutical supply surges. Site managers carry out additional training and periodic deep cleaning of critical lines. Filtration technicians rotate regularly and conduct “four eyes” checks on each batch transfer. All production staff get direct annual feedback, both positive and corrective, linked to test outcomes and real-world customer feedback.

    No two years bring the same mix of technical and market challenges, but regular plant walk-arounds, deep roots in quality assurance, and close relationships with both suppliers and customers remain constants. Each group knows its role, from catalyst selection to post-packing checks—turning what could be routine chemical manufacturing into a process where safety, traceability, and product reliability stay front and center.

    Looking Forward with Polyoxyethylene 35 Castor Oil

    As the push for cleaner labels, transparent supply chains, and higher purity products continues, manufacturers must keep adapting to new expectations. Polyoxyethylene 35 Castor Oil stands as an example of what manufacturing experience can deliver: not just a reliable surfactant, but a material defined as much by the ongoing attention to detail as by its chemical structure.

    Our daily work blends chemistry, safety management, supply coordination, technical problem-solving, and attention to downstream end users. With every truck or drum that leaves the plant, product quality traces back to years of small, careful improvements and a willingness to engage with anyone along the chain—whether it’s an engineer designing a new infusion, a cosmetic developer creating a flagship serum, or a food scientist working out a tricky flavor blend.

    In our eyes, Polyoxyethylene 35 Castor Oil is more than a product number. It represents years of learned experience, continual tweaking, and a direct connection to every party that builds value with each shipment. Manufacturers who see themselves not as mere suppliers but as critical partners in their customers’ value chain will define the next chapter for high-quality chemical ingredients.

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