| HS Code | 974665 |
| Name | Plant-Derived Squalene |
| Source | Plants such as olive oil, sugarcane, and amaranth seed |
| Appearance | Clear, colorless to pale yellow liquid |
| Odor | Odorless or very faint odor |
| Purity | Typically ≥ 98% |
| Solubility | Insoluble in water, soluble in oils |
| Cas Number | 7683-64-9 |
| Molecular Formula | C30H50 |
| Molecular Weight | 410.72 g/mol |
| Melting Point | -75°C |
| Boiling Point | 285°C at 2 mmHg |
| Density | 0.858 g/cm³ at 25°C |
| Refractive Index | 1.493–1.508 |
| Common Uses | Emollient in cosmetics, vaccine adjuvant, dietary supplements |
| Stability | Stable under recommended storage conditions |
As an accredited Plant‑Derived Squalene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | Amber glass bottle with tamper-evident cap, labeled “Plant‑Derived Squalene 100mL,” including batch number, lot date, and storage instructions. |
| Shipping | Plant-Derived Squalene is typically shipped in tightly sealed, food-grade containers or drums to prevent oxidation and contamination. It should be stored and transported in a cool, dry place away from direct sunlight and heat sources. Ensure the shipment meets applicable chemical transport regulations and uses appropriate labeling and documentation. |
| Storage | Plant-derived squalene should be stored in a tightly sealed container, protected from light and moisture. Keep it in a cool, dry place, ideally between 2–8°C (refrigerated conditions). Avoid exposure to air and heat to prevent oxidation and degradation. Proper storage maintains squalene’s stability and quality, ensuring its efficacy for research, pharmaceutical, or cosmetic applications. |
Our plant-derived squalene is manufactured under vertically integrated, GMP-audited processes, offering stable performance in specialized industrial applications. Below, we highlight real-world downstream sectors where squalene achieves high-value functional results, focusing on specific formulation, production, and compliance details critical to each segment.
Pharmaceutical manufacturers incorporate plant-based squalene into dermal products such as ointments and topical gels, where its purity and skin compatibility are crucial for both drug delivery and patient tolerability. Regulatory agencies mandate rigorous control of both active and excipient components, and squalene’s high oxidative stability suits prescription-grade formulations targeting conditions such as eczema and dermatitis. Production lines employ validated mixing and homogenization processes to ensure uniform emollient performance and minimize risk of irritation from oxidation byproducts.
Industry compliance standards
Typical usage ratio
Downstream process integration
Final product types
Cosmetic formulators rely on our material for high-end skin care, where ingredient transparency and oxidative stability are required for brand positioning and regulatory acceptance. Squalene serves as a high-spreadability emollient and a carrier for active botanicals in serums, lotions, and SPF products. Its low comedogenicity and plant-derived source are crucial for clean beauty brands, while manufacturing requires precise blending temperatures and inert atmosphere filling to prevent oxidation.
Industry compliance standards
Typical usage ratio
Downstream process integration
Final product types
Squalene acts as a critical intermediate for sterile emulsion adjuvants, supporting antigen delivery in human and veterinary vaccines. Downstream manufacturers demand traceable plant origins to ensure animal-free status and meet stringent audit requirements. Squalene’s controlled peroxide values enhance emulsion consistency and immunogenic response. Industrial production involves strict segregation from other excipients to avoid cross-contamination and use of oxygen-impermeable storage prior to sterilization and final aseptic filling.
Industry compliance standards
Typical usage ratio
Downstream process integration
Final product types
Nutraceutical manufacturers utilize this raw material as a functional lipid for dietary capsules, valued for its traceable plant origin in vegetarian, halal, and kosher markets. Regulations in food safety differ by jurisdiction, and stability during encapsulation relies on refined squalene integration to prevent hydrolysis and maintain high shelf-life. Large-scale producers implement nitrogen-flushed mixing tanks to circumvent oxidative changes during gelatin or starch-based softgel production.
Industry compliance standards
Typical usage ratio
Downstream process integration
Final product types
Personal care brands focused on premium hair and scalp treatments choose high-purity plant-based squalene to improve combability and reduce scalp irritation in rinse-off and leave-on products. Compliance requires documentation of absence of animal origin, and manufacturing setups monitor microbials and peroxides to ensure formulation stability during high-shear mixing and subsequent bottling stages.
Industry compliance standards
Typical usage ratio
Downstream process integration
Final product types
Competitive Plant‑Derived Squalene prices that fit your budget—flexible terms and customized quotes for every order.
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Making squalene from plants marks a steady shift in how our industry thinks about value and responsibility. For decades, manufacturers leaned on shark liver as the main raw material, but we saw the writing on the wall: this approach put pressure on marine ecosystems and could no longer be justified as the need for sustainability grew. As a chemical manufacturer with years of experience distilling, purifying, and refining high-value compounds, we recognized early-on that plant sources, such as olives and sugarcane, offer dependable yields and remove pressure from fragile wildlife stocks.
Our plant-derived squalene stands out for its purity profile, which sits consistently above 98%, achieved through in-house molecular distillation. The product's clear, odorless, lightweight oil matches the physical and chemical properties found in traditional shark-based squalene, but without any of the ethical concerns. Manufacturers in personal care, pharmaceuticals, vaccines, and health supplements find this switch brings peace of mind alongside reliable performance.
Batch consistency drives everything we do. Testing every lot for peroxide value, color, and residual solvent levels, we catch and correct variations before they reach your doorstep. Analytical data logs from our past two years of output show peroxide values typically under 2.0 meq/kg. This low reactivity translates directly to stability for end products. The refractive index rides at 1.490 – 1.503, and specific gravity between 0.855 – 0.860 (25°C), which tracks closely with historical shark-derived standards.
Every kilogram of oil comes from plant feedstock without residual pesticides—verified through annual third-party audits and our own chromatography suite. Our experience working with large personal care brands has pushed us to maintain heavy metal content far under international thresholds. The squalene pours crystal-clear with a faint golden hue, and nothing feels heavy or tacky.
In cosmetics, our squalene forms the backbone of moisturizers, serums, and sunscreen dispersions. Because it closely mimics human sebum in both structure and function, this ingredient rapidly absorbs into the top layer of skin, improving texture and lending products a natural, non-greasy finish. Our clients report low rates of irritation and notice that squalene helps stabilize typically volatile actives.
In the nutraceuticals market, squalene capsules and softgels find their way into portfolios aimed at heart health, antioxidant delivery, and immune system support. We see R&D groups pushing into new food applications, taking advantage of squalene’s ability to support oil-based fortification in beverages and functional foods. Its oxidative stability gives it a shelf life that outpaces many other plant oils under similar conditions.
The pharmaceutical sector uses squalene as the foundation for emulsion-based adjuvants in vaccine manufacturing. Purity holds even more weight here, and our manufacturing environment mirrors cleanroom standards to prevent bioburden or contamination. Every run involves sterility controls and tight monitoring of endotoxin levels, responding to the demands of critical applications such as injectable vaccines and ophthalmic solutions. Our best practices, built up over ten years of handling high-purity compounds, have been scrutinized through audits from regulators and demanding partners alike.
Choosing plant squalene isn’t just an ethical decision; it’s a practical one. We noticed early in the shift away from shark-derived material that formulation teams welcomed the drop in sourcing risk. Shark squalene supply can fluctuate with fisheries and face regulatory constraints. Plant sources—mainly olives and sugarcane—provide a stable route, unaffected by oceanic bans or quota systems. Our team sources non-GMO olive and sugarcane crops from longstanding partner growers. We track every lot, verifying through supply chain audits that nothing slips through the cracks.
Customers frequently ask if end results differ. Our experience tells us no—analytical and performance testing, both in-house and third-party confirmed, shows equivalence in spreadability, color, viscosity, and oxidative resistance between plant and animal sources. That means end consumers, whether applying a skincare serum or taking a dietary supplement, notice no difference. After making the transition, our bulk customers stopped fielding sourcing complaints and instead highlighted the ease of listing a vegan-friendly ingredient in their marketing.
Operationally, our production partners like the predictable lead times and clear documentation. Plant harvest seasons run like clockwork, and with proper inventory planning, out-of-stock headaches disappear. We keep buffer inventory for critical customers, a practice learned from years driving just-in-time scheduling in ingredients supply chains. Our downstream users appreciate that forecasting gets easier, and last-minute shortages fall away.
Our manufacturing process favors closed systems to minimize oxygen exposure. We've invested in nitrogen-blanketed holding tanks and jacketed lines that help lock in freshness, especially important where squalene will be formulated with heat-sensitive or expensive actives. Routine testing catches any increase in peroxide values, and batches that don’t hit our benchmarks get sent for rework, not shipment. Traceability lives at the core of every lot: we maintain electronic batch records, with full test data available down to the smallest scale.
We worked directly with large multinational beauty companies and tight-knit pharmacy compounding networks. Both types of partners demand proof of reliability—proof we provide through certificates of analysis, open samples for third-party testing, and full transparency on our test methods. Over time, the volume of customer claims dropped as our internal defect rate slid below our own KPIs.
Squalene’s sensitivity to light and air puts pressure on storage and handling. Our warehouse teams keep inventory in UV-blocked drums at controlled temperatures. This attention to detail ends up making a difference in how well downstream products retain clarity and scent. Feedback loops from repeat customers allowed us to fine-tune our packaging, moving from traditional drums to lined, light-filtering containers for exports with long shipping times.
Traditional shark squalene extraction put a burden on global fisheries, and those watching regulatory movements in the EU, US, and APAC regions know the days of animal origin material are numbered. By turning to plant sources, our operation sidesteps these tightening restrictions—ensuring our customers keep pace regardless of geography or shifting regulatory codes. In regions such as the EU, vegan-friendly claims open new doors for brands eager to communicate a clean label story.
Our waste streams from squalene refining don't find their way to landfill or incinerators. Spent olive pulp and leftover sugarcane fraction find secondary life as compost or biofuel feedstock. We treat effluent to local standards well in advance of mandatory timelines. Long before policy required it, our team tracked the reduction in carbon footprint versus animal-sourced alternatives. Auditable records from three years of production show a measurable drop in greenhouse gas emissions for each metric ton delivered.
Adopting plant squalene forced us to tackle some new engineering problems. Among these: keeping batch color stable across different harvests—something the plant world brings in spades. Our solution married better filtration at the crude oil stage with tighter chromatographic separation in the refinery. We found that keeping lots segregated by harvest date, and adjusting process parameters accordingly, stopped the drift in color values that bedeviled early trials. Experience showed us that investing in better analytics early avoided more costly rework later.
Transparency matters in ingredient supply. We open our doors annually for site inspections and invite customers to witness process validations. We believe this builds trust not by claim, but by proof. Long-term partners trust our audit history and our willingness to troubleshoot issues as they arise—whether the question comes from a fragrance house in southern France or a nutraceutical formulator in Japan.
Switching away from animal inputs wasn’t all smooth sailing. Sourcing reliable, residue-free plant feedstock at scale took us years of relationship-building. Bad harvests can throw off yield and purity. We learned to keep close tabs on growing partners and backed up critical supply with farming cooperatives on two continents. Even then, establishing robust quality protocols took time; early runs sometimes failed to meet odor benchmarks due to volatile plant secondary metabolites. Iterative work on deodorization reduced unwanted notes and set a new clean standard for plant squalene.
The transition to plant squalene stretched our analytical chemistry labs. Routine pesticide screening now complements traditional tests like iodine value and refractive index. Investing in expanded chromatography allowed our lab staff to catch minor contaminants that might arise from crop differences. We now routinely offer extended pesticide and heavy metal panels, and share those result summaries with formulation partners.
Plant-derived squalene’s future may ride, in part, on further process automation and reactor upgrades. As demand grows, we keep old pain points in mind: scaling without sacrificing transparency or failing to support clients through formulation troubles. Developing in-process sensors for real-time peroxide monitoring, for example, cut QA/QC bottlenecks and allowed us to supply faster turnarounds for customers working through R&D phase changes. Not every innovation sticks—sometimes a promising control method burns up staff time with little payoff—but those that work get standardized quickly.
The broader industry has called for greater traceability in recent years. Digital batch tracking and third-party certifications helped answer the need. Our regulatory and compliance team maintains up-to-date MSDS, Kosher/Halal, and allergen statements to smooth the path for downstream labels. We know how long paperwork delays can gum up a new product launch, so we keep docs in ready order, scan for new compliance rules, and keep regular dialog with certifiers.
Customers sometimes ask whether anything is sacrificed in shifting from animal to plant sources. Side-by-side analytical results show no meaningful difference in fatty acid composition, density, or viscosity—the metrics that matter in creams, emulsions, and ingestible delivery forms. Physical handling for the operator is unchanged. Vegan, plant-derived claims mean that more finished products qualify for broader market appeal, important for both developing and mature economies.
Shelf life also stays high. In real-time and accelerated stability studies, properly stored plant squalene approaches three years' open shelf life—on par with the best shark-derived lots. Tight specs on free fatty acid content and peroxide values help finished products stay fresh longer. Because no protein is present, allergy risks drop.
Economic questions also arise. Initial raw material costs for plant oil extraction tended to run higher in early years, but as agri-processing scaled up and the industry shed inefficient intermediaries, squalene prices stabilized. Today, our pricing model delivers cost equivalence or modest premiums compared to shark origins—even as we expanded quality controls and waste management technology.
Food and cosmetic producers looking for future-proof ingredients can rest easier with plant squalene. Seasonal volatility from shark harvests, combined with sporadic bans, can destabilize production calendars. Our partners plan years ahead with scheduled shipments and multi-year supply contracts drawn up against farm output. We help clients with inventory planning using forecast models fine-tuned from years managing commodity and specialty ingredient flows.
Unpredictable raw material purity used to threaten batch consistency for high-end skin care or pharma use. Plant squalene let us standardize both raw input and process flow, catching outliers early. We worked with customer formulation teams to troubleshoot compatibility and provided trial samples to speed up qualification, smoothing the switch.
To lock in quality up the chain, we hold annual training for our supplier base. Farmer workshops cover best practices in organic pest control and crop rotation techniques that support consistent squalene yield and food safety. Our production team travels out into the fields to confirm compliance, not just on paper but in practice, backing up our promises with boots-in-the-dirt observation.
Customer feedback shaped many changes in our plant squalene journey. When users saw minor residue or haze in oil for pharma applications, we tightened filter grades and reconfigured distillation parameters. Cosmetics makers with strict odor thresholds taught us to refine deodorization again and again. Each complaint gave us a roadmap to the next process tweak. Repeat business and multi-year contracts tell us where we’re on the right track.
Support does not end after the sale. Our technical services staff answers questions about how to blend squalene with common excipients, how to handle stability in tropical climates, and how to comply with patchwork labeling rules around the world. No matter the sector, every client solution feeds improvements back into our own manufacturing playbook.
Years of work distilling, testing, and refining plant-derived squalene taught us that value goes beyond the balance sheet. Ethical sourcing supports ecosystems, and transparent processes empower our customers to stand behind their finished products. The ingredient keeps pace with the growing expectations for traceability, purity, and documentation.
As regulations evolve and environmental concerns shape consumer behavior, a steady partnership with plant-based squalene manufacturers supports more than just smoother skin or cleaner label claims. It represents an industry built for the future, responsive to change, and accountable to both people and planet. From the very first seed to the last drop shipped, our team’s commitment to quality safeguards your formulation and global reputation alike.
Plant-derived squalene is transformation in practice—not just for raw material sourcing, but also in safety, product performance, and peace of mind for those who work with it every day.