|
HS Code |
334183 |
| Cas Number | 484-12-8 |
| Molecular Formula | C15H16O3 |
| Molar Mass | 244.29 g/mol |
| Appearance | White to yellowish crystalline powder |
| Melting Point | 86-87°C |
| Solubility | Slightly soluble in water, soluble in ethanol and DMSO |
| Purity | ≥98% |
| Chemical Class | Coumarin derivative |
| Storage Condition | Store in a cool, dry place, away from light |
| Source | Osthole is isolated primarily from Cnidium monnieri |
| Synonyms | Osthol; 7-Methoxy-8-(3-methyl-2-butenyl)coumarin |
| Iupac Name | 7-Methoxy-8-(3-methyl-2-buten-1-yl)-2H-chromen-2-one |
As an accredited Osthole factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | Osthole is packaged in a sealed, amber glass bottle containing 25 grams, labeled with product name, purity, and safety information. |
| Shipping | Osthole is shipped in tightly sealed containers, protected from moisture, light, and heat. Packaging complies with safety regulations, using glass or plastic bottles, often cushioned to prevent breakage. Proper labeling and documentation are included, and transport is via reliable carriers to ensure safe and prompt delivery while maintaining the compound’s integrity. |
| Storage | Osthole should be stored in a cool, dry, and well-ventilated area, away from direct sunlight and moisture. Keep the container tightly closed when not in use, and store it in a tightly sealed, labeled container. Avoid exposure to heat and incompatible substances such as strong oxidizing agents. Proper storage ensures stability and prevents contamination or degradation of the chemical. |
Competitive Osthole prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please contact us at +8615365186327 or mail to sales3@ascent-chem.com.
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Tel: +8615365186327
Email: sales3@ascent-chem.com
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Osthole attracts attention for its versatility and time-tested performance in several industries. We manufacture Osthole at our own production site, keeping careful control over every step. Years in phytochemical production have taught us one lesson: purity and stability give real value to our customers, not just technical numbers or flashy promises. Our Osthole embodies this principle. Harvested from Cnidium monnieri fruits, the process starts far upstream with responsible sourcing and traceability, which sits at the root of everything we do.
We insist on direct input selection. Our technicians hand-inspect raw botanical materials, rejecting batches with visible defects or improper curing. This low-tech filter at the gate still outperforms any sophisticated gadget in their hands. Seasonal factors—especially monsoon impact on seed moisture, and cases of pesticide drift from nearby fields—make regular supplier audits necessary. A supply chain built on handshakes and years of collaboration means our Osthole always begins life with real botanical integrity.
Our extraction process uses simple solvents and gradually steps up refinement. We distill, filter, and recrystallize, guided by our internal knowledge rather than dogma. Extracted Osthole typically appears as a white crystalline powder. We standardize Osthole to 98% minimum purity as confirmed by HPLC, with routine third-party assays. Plenty of users have seen fake Osthole on the market, blending starch or talc to stretch profits. Tongue-in-cheek, some call it 'almost-le', noting the difference once they finally encounter the authentic product. Our team sets well-defined upper limits for related compounds—peaunidin, imperatorin, xanthotoxin—and never lets them slip past our quality lab. Moisture, ash, and heavy metal profiles remain extremely tight too, a point where manufacturing diligence outweighs any marketing claim.
The smell remains faint, sometimes sweet and slightly herbal, proof of minimal oxidization. You can feel the structural difference in granule shape after slow crystallization. Some resellers don’t even open their drums; we taste and test every batch. This real-plant discipline produces an Osthole powder free from gritty aftertaste. We see consistent results not from luck, but from fixable details and small improvements made batch by batch.
Osthole supports agricultural, pharmaceutical, animal health, and cosmetic formulations. Most of our customers want more than a raw extract; they want substance and proof of long-term supply. In crop protection, Osthole fits as a botanical insecticide and growth regulator. Chinese agronomists started field trials decades ago, noting the effect on aphids, nematodes, and powdery mildew. Our partners in crop science still send us live plant samples to fine-tune dosing. They report visible crop improvement and a lower chemical residue burden—valuable for producers locked out of export markets by strict MRL limits. Formulators tell us our Osthole disperses smoothly in their tank mixes, doesn't create clumps, and resists photodegradation during storage.
In animal nutrition, Osthole gets formulated into natural feed additives to improve resistance against intestinal parasites and boost feed conversion. Specific poultry producers speak openly about reductions in coccidial outbreaks after using our material. We keep impurities below 0.5%, avoiding unpredictable side effects in young animals. The same philosophy applies in pet-care product development, where Osthole gets blended into flea and tick formulations.
Pharmaceutical clients ask us to guarantee trace alkaloid profiles. In one case, a researcher pointed out an odd cytotoxicity result, which our investigation traced to a minute impurity in a competitor’s sample. We raised our own alarm: one poorly managed purification can jeopardize years of development. We responded with additional fractional crystallizations, running every batch past both LC-MS and GC-trace analysis. Our Osthole delivers batch-to-batch consistency in supporting anti-inflammatory and vasorelaxant research, meeting exacting monograph targets for recognized pharmacopoeias.
Cosmetic formulators often inquire about Osthole’s stability under strong UV, as well as particle size distribution in microemulsions. In sunscreen blends, Osthole stabilizes actives and doesn’t cause yellowing—even after forced aging trials at 45°C for eight weeks. This stability results from two changes: gentle drying and sequence-controlled crystallization, which we refined through process tweaks and close collaboration with formulation chemists.
Buyers ask whether our Osthole is different from bulk market alternatives. Here’s what we see: mass-repacked Osthole on trading platforms often contains variable moisture, and sometimes gets bulked up with excipient fillers. Lower quality powders feel gritty or clump quickly in standard solvent tests. Others turn faintly yellow after only a few months in storage, a dead giveaway of poor stabilization and careless packaging. We never let expired or recycled Osthole reach our clients thanks to rigorous shelf-life studies, photographic retention samples, and ongoing batch reviews going back years.
Manufacturing at source brings us closer to the product than trading ever could. We control every batch, work alongside experienced technicians, and maintain our own records—all elements that get lost in third-party repacking. The difference shows up in spectroscopy, of course, yet most often clients notice it during development or production scaling. They ask for a small batch, then quickly reorder, having hit fewer compatibility problems and less off-flavor during blending. In our experience, anecdotal feedback tells us more about product difference than any SD or RSD figure.
Adulteration has plagued the Osthole marketplace since prices rose about a decade ago. Some suppliers blend coumarin-rich byproducts and off-grade herbal extracts, banking on superficial resemblance for less-discerning buyers. After months in storage, though, these shortcuts reveal themselves through precipitation, musty aroma, and IR spectra. We keep our supply chain short, run full transparency on test results, and avoid every shortcut. The results show in zero complaints about foreign odor or insoluble flocculation.
Most requests center on purity and reproducible analysis. We set Osthole content above 98%, moisture content below 1.5%, and ash content below 0.5%. We run every batch through HPLC, GC, and UV-Vis testing, and occasionally check for unusual degradation products by LC-MS. Our heavy metal checks keep cadmium, lead, and mercury beneath pharmacopeial limits, but long-running internal studies matter more than a stamped certificate.
Shelf-life for our Osthole, protected in HDPE bottles or multi-layer paper sacks, stretches beyond two years under 25°C. We treat stability not as marketing, but as a recurring research challenge. Our internal batch archives—dozens of sealed reference samples—let us evaluate long-term oxidation and caking in ways third-party traders rarely match.
Particle size distribution runs tight, peaking near 80 mesh as standard. For clients needing finer powder (down to 100 mesh), we clean grind and micronize without overheating or adding agents. This focus on physical form lets our Osthole blend in suspensions and feeds cleanly—no ‘float’ or settling issues commonly reported with commercial grades.
We do not use artificial preservatives or colorants. The only stabilizers used come from within the plant profile itself. We do not blend with microcrystalline cellulose, rice starch, or lactose, habits we often see elsewhere. What you get is pure Osthole, shaped by years of small technical improvements and field feedback.
Trends in Osthole demand shifted during the last decade. Early buyers steered by price alone, looking for whatever source could undercut the market. Gradually, regulatory tightening—MRL checks in agriculture, identity confirmation for APIs—brought scrutiny and skepticism. Now, most buyers lean toward manufacturers with proof of origin, track history, and a record unblemished by supply scandals. We meet these rising expectations by keeping our records transparent and sharing analytic evidence upfront. We encourage regular plant tours and audits. Clients often send their own teams, not stopping at a handshake but personally validating our process.
Our staff includes veteran extraction operators and new-generation chemists who debate improvements openly. Sometimes a suggestion as simple as slower heat ramping during drying cuts impurity peaks by several tenths. We see progress through iteration, not mythical breakthroughs. Feedback travels both ways: some of our detection methods evolved directly from client observations about granule ‘feel’ in high-volume mixers or cloud point shifts in organic solvent systems.
A few users, especially in animal or human applications, need to know more than chemical stats. They ask about the safety margin of Osthole, allergen risk, and stewardship in sourcing. We support them in several ways. Our Osthole qualifies as non-GMO, with full disclosure of country and region of origin. Ethanol used in extraction never leaves more than 100 ppm in finished powder, and we confirm absence of PAHs and solvent residues using SPME and GC-MS.
Allergen questions arise less often for Osthole than for protein-rich botanical extracts. Still, we log plant-borne allergen reports and take requests for custom testing, especially for companies formulating for pets or the elderly. We guarantee no gluten, soy, or dairy contact in our handling chain; all storage areas get regular environmental swabs and secondary pest monitoring.
Osthole’s safety margin in targeted applications depends on proper dose and context. For those serving agriculture, we remind users to validate dosing on their own crops and to reserve bedded field trials before large-scale application. Cosmetic and pharmaceutical customers maintain full responsibility for suitability testing, yet we provide source data and impurity specs along with batch shipments. Our field representatives never shy from sharing both successes and challenges; real partnership grows from open dialogue about performance under actual conditions rather than pretty theory.
Regulatory evolution sometimes presents unexpected hurdles: portfolio reviews, temporary market bans, or shifts in ‘novel food’ classification. Our technical staff monitor jurisdictional changes on Osthole and related coumarins, updating formulation partners on any changes that could affect documentation, labeling, or end-market acceptance. Experience tells us that documentation delays can cost companies thousands in supply chain interruptions. We treat this as a real-world risk, not an abstract compliance matter.
Many of our best customers have worked alongside us through multiple product generations. They walk our production halls, sit down for impromptu whiteboard sessions, and challenge our chemists. These visits foster accidental discoveries that never show up on glossy sales sheets—changes in dried Osthole’s stickiness when ambient humidity crosses 60%, or slight aroma differences tied to harvest altitude. These small findings shape our Osthole as much as HPLC graphs do.
Repeat buyers often suggest process tweaks, asking us to fine-tune crystal size for improved solubility or to extend dry blending for their unique recipes. Some request pre-dilution or granulation, but we always base any modification on fresh in-house tests, with both parties signing off on the result. Our batch flexibility and hands-on philosophy keep product integrity intact—never trading quality for volume.
We keep strong archives of all feedback and track individual sample histories for every long-term customer. This back-and-forth has, on occasion, rescued a project from batch inconsistency or missed regulatory targets. Our open-door policy means visiting technical staff can see their exact batches during production, not just a generic “run-of-mill” output.
Few markets change as quickly as natural ingredients. New intermediaries emerge, flashy claims hit the market, but underlying process knowledge remains scarce. Adulteration issues and credential inflation have eroded buyer confidence. We recognize this. The right move isn’t shouting louder, but quietly documenting results and maintaining open lines of communication. Our Osthole stands as a record, not just a product. We keep chromatograms, stability charts, and deviation notes, ready to share as needed.
We've faced sharp shortages during years of drought or disease outbreaks in primary growing regions. In these situations, we never reached for easy substitutes or stretchers. Instead, we drew on our stockpile, built up through careful planning and investment in off-season purchases. Long-term contracting protects both us and our regular clients, preventing panic buying and volatile pricing.
Some customers suffer batch failures from buying open-market Osthole: bad solubility, mystery aroma, or simple mislabeling. We see this often when buyers move from trial to scale-up and suddenly hit a wall. Our team remains available for both troubleshooting and interpreting odd lab results. Once, a partner’s formulation began foaming in pilot-scale blending; joint analysis found micro-particulate contamination in a third-party Osthole. Switching to our supply resolved it, making quality a business advantage, not just a technical checkbox.
Relying on a manufacturer who owns the process, keeps historical batch records, and invests in steady improvement, shields your own products from this fractured margin-hunting market. We want our Osthole to inspire ongoing feedback, gradual process adjustment, and the kind of partnership that creates real, reproducible results.
Future demand for Osthole keeps evolving. As more sectors embrace green chemistry, botanical actives, and traceable supply chains, the market for high-quality Osthole grows more discerning. Technical users focus on purity, blending performance, and multi-year stability, while end-users seek transparent sourcing and the confidence that comes with proven quality. We stay involved with ongoing studies into Osthole’s safety, functional use, and technical compatibility, sharing knowledge back to our partners where it strengthens both products and relationships.
As a direct manufacturer, our founding principle remains unchanged: each batch of Osthole must meet not just regulatory requirements but our own standards for reliability and customer trust. We stand ready to support new developments, troubleshoot challenges, and refine our practices as the industry grows. Whether your next project focuses on crop solutions, new health formulations, or advanced material science, our Osthole provides a proven, transparent foundation for your innovation.