|
HS Code |
251192 |
| Productname | Luteolin-7-O-Neohesperidoside |
| Casnumber | 21637-25-8 |
| Molecularformula | C27H30O15 |
| Molecularweight | 594.52 g/mol |
| Appearance | Yellow powder |
| Solubility | Soluble in methanol, slightly soluble in water |
| Meltingpoint | 210-215°C |
| Source | Plants, especially in some members of the Lamiaceae family |
| Purity | Typically ≥98% (HPLC) |
| Storagetemperature | 2-8°C |
| Chemicalclass | Flavone glycoside |
| Synonyms | Cynaroside-7-neohesperidoside |
| Iupacname | (2S,3R,4R,5S,6R)-2-[[(2R,3R,4R,5R,6S)-4,5-dihydroxy-2-(hydroxymethyl)-6-[5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-3-yl]oxyoxan-3-yl]oxy]-6-(hydroxymethyl)oxane-3,4,5-triol |
As an accredited Luteolin-7-O-Neohesperidoside factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | Luteolin-7-O-Neohesperidoside is packaged in a 25 mg amber glass vial, sealed for light protection and labeled with storage instructions. |
| Shipping | Luteolin-7-O-Neohesperidoside is shipped in securely sealed, airtight containers to maintain stability and purity. It is packaged with appropriate cushioning and labeled according to chemical transportation regulations. Transport is typically at ambient temperature, unless specified otherwise, ensuring the compound’s protection against moisture, light, and temperature fluctuations during transit. |
| Storage | Luteolin-7-O-Neohesperidoside should be stored in a cool, dry place, protected from light and moisture. It is recommended to keep the compound in a tightly sealed container at -20°C or lower to maintain stability and prevent degradation. Avoid repeated freeze-thaw cycles and exposure to air. Ensure proper labeling and follow laboratory safety guidelines for chemical storage. |
Competitive Luteolin-7-O-Neohesperidoside prices that fit your budget—flexible terms and customized quotes for every order.
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In our years developing plant-based actives, few molecules have prompted as much demand as Luteolin-7-O-Neohesperidoside. Countless research teams come to us requesting this flavonoid, looking for ways to advance their pharmaceutical, nutraceutical, or food science projects. The growing interest doesn’t surprise us. Customers consistently tell us the unique glycoside link in Luteolin-7-O-Neohesperidoside offers biological benefits that set it apart from its parent compound, luteolin, and from other glycosylated flavonoids.
Supplying Luteolin-7-O-Neohesperidoside brings new challenges every season: difficult extractions from natural sources, perfection in purification processes, and an ever-evolving list of specifications from clients worldwide. As manufacturers, we have adapted our processes, investing in both upstream agricultural partnerships and downstream purification technologies to address these needs. Luteolin-7-O-Neohesperidoside is not a commodity – it is a precision product. Each batch we release marks the conclusion of hundreds of hours optimizing every stage, from raw plant collection through to packaging the final powder.
Luteolin-7-O-Neohesperidoside carries a luteolin backbone with a neohesperidose sugar attached at the 7-position. This specific sugar linkage makes extraction and synthesis more challenging than producing simpler flavonoid glycosides such as luteolin-7-O-glucoside. Our process starts with botanicals known for high flavonoid content. We extract, purify, and analyze every lot using advanced chromatography and mass spectrometry. Typical batches meet a minimum assay of 98% purity, with moisture controlled below 1.5%. We take pains to remove related flavonoids and residual solvents through multi-stage purification.
Many clients ask us how the neohesperidose moiety affects the physical and chemical properties compared to similar compounds. Unlike more common glucose conjugates, the bulkier disaccharide impacts solubility, taste, and biological interactions. Our standardized product appears as a fine yellowish powder, with solubility characteristics documented in both water and ethanol. We always encourage users to review our most recent batch analyses, as subtle variations in source plant matter can sometimes affect color or minor physical characteristics, but rarely the core purity or identity.
Reliable access to quality Luteolin-7-O-Neohesperidoside depends on understanding the limitations of natural sources. The molecule occurs in several plants, yet concentrations are often low. Plants such as Chrysanthemum indicum and certain citrus species harbor the glycoside, but each harvest can bring wide swings in content due to weather, soil conditions, and even the timing of leaf or flower collection.
We’ve spent years refining our agricultural contracts and extraction protocols. Over the past decade, we’ve noted that wild-harvested sources tend to yield more impurities and less reliable compound concentrations than controlled agricultural partners. Our internal teams regularly audit fields, examine crop health, and sometimes run on-site extraction pilots to head off losses in yield. The challenge is consistent: match the growing global demand for Luteolin-7-O-Neohesperidoside with sustainable, traceable sourcing.
Extracting the glycoside without degrading it is an art in itself. Many solvents can break the sensitive bond between the flavonoid and the sugar, so we had to fine-tune our extraction and purification conditions to assure compound integrity. Once the extract is produced, it passes through several filtration and chromatography cycles, each tailored to exclude other glycosides, aglycones, and plant matrix components. This level of precision comes naturally to us after years refining similar products, but it is the specificity of Luteolin-7-O-Neohesperidoside that raises the stakes and motivates our chemists.
Our analytical team applies a rigorous validation program for every production lot. We use HPLC paired with diode array detection and mass spectrometry to verify the identity and purity. Test results from customers worldwide confirm that our Luteolin-7-O-Neohesperidoside consistently matches or exceeds international standards for purity.
Through routine analysis, we also check for heavy metals, residual solvents, and pesticides—factors sometimes overlooked by less experienced manufacturers. We see this diligence as critical both from a regulatory and ethical perspective. Years ago, a client’s lab flagged a trace contaminant in a competitor’s product, one that originated in a poorly cleaned solvent system. That incident reinforced our commitment to regular equipment maintenance, careful supply chain audit, and dual-lab confirmation of our final product reports.
We encourage open exchange with our users. Several research partners have approached us with questions about optical rotation, melting point data, or new applications that require tailored powder fineness. Our team responds quickly, sometimes adapting our milling or drying protocol to help projects move forward. Transparency with every batch report means users know exactly what goes into their studies—not all manufacturers share this commitment. Our record of traceable certificates of analysis, available upon request, makes collaboration straightforward.
Luteolin-7-O-Neohesperidoside draws interest for its antioxidant and anti-inflammatory properties—areas where luteolin itself shows promise, but the neohesperidose conjugate sometimes displays improved solubility or bioavailability. Researchers from food technology and pharmaceutical backgrounds use our product to investigate these differences in cell lines or animal models.
Our largest-volume customers come from the food supplements, functional food, and cosmeceutical industries. They rely on clean, consistent phytoactives and rarely compromise on purity. Some researchers compare the bioactivity of Luteolin-7-O-Neohesperidoside to similar molecules found in traditional herbal medicines, but the controlled manufacturing environment allows for exact dosing and repeatable results. Product developers have reported success formulating powdered supplements, extruded snack bars, and topical preparations from our material.
Pharmaceutical teams note that glycosylation can affect not just solubility, but stability against oxidation or enzymatic breakdown. Luteolin-7-O-Neohesperidoside’s stability profile opens new research pathways in oral delivery and controlled release mechanisms. Unlike crude plant extracts or unknown blends, our pure compound supports clinical trial protocols.
A handful of groups seek to use our product as a reference standard for analytical method validation. Measuring the precise content of this glycoside in consumer products or biological samples hinges on reliable standards—a niche we serve carefully. As scientists ourselves, we appreciate the distinction between a reference compound for analytical work and bulk active ingredients for consumer-facing goods.
Comparisons with similar flavonoids often come up. Luteolin-7-O-glucoside and rutin are two analogues frequently requested alongside Luteolin-7-O-Neohesperidoside. The technical difference lies in the sugar: where glucosides or rutinosides feature simpler disaccharides, neohesperidose brings unique steric and chemical properties. Our chemists routinely demonstrate to clients that different glycosides can produce distinct results in cell uptake, flavor profiles, or shelf stability.
The effort to separate Luteolin-7-O-Neohesperidoside from closely related compounds challenges even skilled manufacturers. Relying on plant extracts alone often leaves a mixture, each flavonoid with similar retention properties during chromatography. Our investment in preparative HPLC and column design pays off here, as we consistently resolve the target molecule to greater than 98%—a figure not guaranteed by all suppliers. Some companies offer blends or impure grades, but our clients need and expect certainty.
A few customers initially ask whether a less purified product, or even luteolin itself, could substitute in their applications. Our experience suggests this shortchanges both lab studies and product lines. The neohesperidose moiety alters both physical interaction (with excipients, for example) and biological effect compared to the aglycone. Without this precision, results can mislead. Several teams confirm by direct side-by-side tests using our approved lots; the differences are not theoretical.
Beyond purity, we pay close attention to batch uniformity in moisture and particle size. Some industrial applications require particular powder flow properties, and inconsistent milling can ruin downstream processing. We invested early in automated sifting and nitrogen drying lines, ensuring our Luteolin-7-O-Neohesperidoside arrives at specification and avoids caking or clumping that might affect solubility or blending in end use.
Manufacturing Luteolin-7-O-Neohesperidoside in modern quantities isn’t just a technical puzzle—it is an ethical responsibility. Plant-derived actives depend on healthy relationships with growers and respect for land. Our supply chains stretch to four countries, but every contract comes with traceability requirements and third-party verification of growing practices. We prohibited supplies from biologically sensitive or over-harvested regions, even if this limited our seasonal volumes.
Waste reduction features strongly in each production run. Extracting flavonoids creates significant plant residue. Some years ago, we partnered with regional biogas facilities to divert these organic leftovers from landfills. Not only did we reduce disposal costs, but we also contributed to local renewable energy. Little improvements like these, repeated batch after batch, make our operations more responsible and reliable.
Transport—both inbound raw materials and outbound finished product—demands careful logistics. Our batches ship with full documentation, detailing origin and all critical process steps. Inspectors and auditors from customer companies frequently visit manufacturing sites, sometimes unannounced, and we welcome this openness. Every partner in our value chain knows our standards and audits our records. This is especially important as global focus turns to supply chain ethics for food and pharmaceutical ingredients.
As interest in Luteolin-7-O-Neohesperidoside expands, our facility teams adapt and innovate. Over the last five years, demand for higher-purity material rose. At the same time, more users requested smaller quantities for pilot studies and research validation. We responded by installing new fractionation systems and scaling downstream packaging lines for unit pack flexibility, eliminating waste and meeting niche requests efficiently.
We track academic and patent literature, learning from new advances in both chemical synthesis and biological application. Several research groups, after using our Luteolin-7-O-Neohesperidoside, published studies exploring its anti-inflammatory and antioxidant action in animal models, each confirming the critical role that sugar conjugation plays in modulating activity. Being in direct contact with the research community keeps us up to date and challenges us to refine both quality and production volumes.
Some recent projects focus on microencapsulation, aiming to improve taste masking and shelf life in finished formulations. Our formulations group works in tandem with R&D teams to trial new stabilizer blends, adjusted milling, and advanced spray-drying. Direct communication between our scientists and technical clients often sparks breakthroughs—ideas that go beyond standard protocols. This collaboration drives our continuous improvement and keeps our product line competitive.
Digitization has helped as well. Inventory systems track every raw material and finished product lot, flagging deviations before they affect quality. We provide customers with detailed digital documentation, including batch-specific spectra and certificates, within hours of request. This transparency is not simply a checklist item for compliance; it empowers our users to make confident, timely decisions in their own work.
Luteolin-7-O-Neohesperidoside manufacturing faces real hurdles. Sourcing is one: natural variation in source material creates swings in content, threatening both yield and cost structure. By contracting directly with select growers and offering agronomic support, we help ensure consistent material. In lean crop years, we sometimes pay above-market to encourage continued cultivation, rather than switching to less reliable or unsustainable overseas suppliers.
Maintaining purity and identity through process changes also brings challenges. Small shifts in extraction temperature, solvent composition, or filtration rates can affect both yield and quality. We overcome this by installing automated controls and redundant monitoring. Our technical teams run weekly process reviews, consulting both in-house documentation and external resources.
Fraud and contamination remain risks in the global supply chain. Years ago, the market saw cases of adulteration with synthetic flavonoids, threatening end-user safety and undermining trust. Our internal QC teams test for known adulterants and run both targeted and non-targeted screens. We won’t accept plant shipments unless audit trails match and verification labs confirm identity. Building trust means policing not just what leaves our factory, but what enters as well.
Regulatory compliance grows more complex every year. Regions differ in allowable residual solvent thresholds, labeling requirements, and reporting standards. Our compliance team interacts directly with counterparts in customer companies, facilitating product registration and documentation to meet each jurisdiction’s needs. Our experience managing these complexities gives repeat customers confidence as they expand into new markets.
Customers bring new application ideas and product criteria, and our success depends on listening deeply. We engage in routine technical exchanges, request feedback from ongoing research, and sometimes provide specialized material for pilot runs. When a user highlights a minor issue—such as an unexpected solubility issue in an otherwise standard batch—our technical teams investigate, respond, and often propose new protocols.
Training remains key. New process operators learn directly from our most experienced staff, with annual refreshers and interdepartmental exchanges. Ongoing education on raw material handling, process hygiene, and record maintenance pays off in superior product consistency. Visitors frequently mention the collaboration and professionalism present in our manufacturing team.
New sustainability concerns have prompted us to consider greener solvents, waste minimization, and energy-efficient equipment. We share research findings and involve supply chain partners in our improvement plans. Where new regulations or market expectations arise, we adapt quickly and share these changes with our clients.
Customers across six continents trust our Luteolin-7-O-Neohesperidoside for dependable performance and documentation. We never rest on our track record. Each feedback, challenge, or regulatory change is an opportunity for further refinement.
Scientific interest in Luteolin-7-O-Neohesperidoside won't wane anytime soon. New studies keep uncovering potential health benefits, expanding its application in pharmaceuticals, functional foods, and cosmetics. The need for ultra-pure, well-documented supply grows alongside those ambitions. Our investment in both process technology and educated staff ensures we keep meeting rising expectations for specification, safety, and transparency.
As manufacturers, we see ourselves not simply as suppliers but as collaborative partners invested in the progress of our clients’ research and the growth of downstream industries. Each season, our teams revisit source partnerships, invest in process upgrades, and train on new standards. Our aim is the same as scientists and product developers: clear documentation, reliable supply, and a deep respect for the integrity of Luteolin-7-O-Neohesperidoside as a unique natural compound.
