Heme

    • Product Name: Heme
    • Alias: heme
    • Einecs: 206-373-7
    • Mininmum Order: 1 g
    • Factroy Site: Yudu County, Ganzhou, Jiangxi, China
    • Price Inquiry: admin@ascent-chem.com
    • Manufacturer: Ascent Petrochem Holdings Co., Limited
    • CONTACT NOW
    Specifications
    HS Code 906035
    Name Heme
    Chemical Formula C34H32FeN4O4
    Molar Mass 616.49 g/mol
    Component Of Hemoglobin
    Color Red
    Central Metal Iron (Fe2+)
    Biosynthesis Location Mitochondria and cytosol
    Main Function Oxygen transport
    Solubility Low in water
    Structure Type Porphyrin ring
    Occurrence Animals, plants, and microorganisms
    Degradation Product Bilirubin
    Uv Absorption Soret band at ~400 nm
    Oxidation States Fe2+ (ferrous), Fe3+ (ferric)
    Medical Relevance Porphyrias, anemias

    As an accredited Heme factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Heme is supplied in a 10 mg amber glass vial, sealed with a rubber stopper and aluminum cap, clearly labeled for laboratory use.
    Shipping Heme should be shipped at ambient temperature in clearly labeled, secure packaging to prevent contamination or degradation. Avoid direct sunlight and extreme temperatures during transit. Ensure documentation includes safety data and handling instructions. For large or sensitive quantities, consider cold packs and expedited shipping for optimal stability and compliance with applicable regulations.
    Storage Heme is typically stored in a cool, dry, and well-ventilated area, away from light and incompatible substances such as strong oxidizers. It should be kept in tightly sealed containers to prevent moisture absorption and degradation. Proper labeling and secure storage minimize contamination and accidental exposure, ensuring the integrity and safety of the heme for laboratory or industrial use.
    Application of Heme
    Purity 99%: Heme Purity 99% is used in pharmaceutical synthesis, where it ensures high yield and reduced impurities in final products. Molecular Weight 616.49 g/mol: Heme Molecular Weight 616.49 g/mol is used in biosensor development, where it enables accurate detection and consistent sensor calibration. Particle Size <5 μm: Heme Particle Size <5 μm is used in cosmetics formulations, where it provides uniform dispersion and enhances color stability. Melting Point 235°C: Heme Melting Point 235°C is used in high-temperature processing, where it maintains structural integrity and prevents product degradation. Stability Temperature 120°C: Heme Stability Temperature 120°C is used in food coloring applications, where it guarantees color retention during pasteurization. Solubility in Water 10 mg/mL: Heme Solubility in Water 10 mg/mL is used in beverage fortification, where it allows homogeneous nutrient distribution. Viscosity Grade Low: Heme Viscosity Grade Low is used in injectable formulations, where it enables smooth administration and minimizes injection force. pH Range 6.5-7.5: Heme pH Range 6.5-7.5 is used in cell culture media, where it supports optimal cellular proliferation and metabolism. Residual Solvent <0.5%: Heme Residual Solvent <0.5% is used in nutraceutical manufacturing, where it ensures product safety and regulatory compliance. Oxidation Stability >24 h: Heme Oxidation Stability >24 h is used in meat analog production, where it extends product shelf life and maintains desirable flavor.
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    For samples, pricing, or more information, please contact us at +8615365186327 or mail to admin@ascent-chem.com.

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    Email: admin@ascent-chem.com

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    Certification & Compliance
    More Introduction

    Introducing Heme: Experience, Reliability, and Insight from the Manufacturer

    What Drives Us to Produce Heme

    Industrial chemistry shapes many aspects of modern life, but few molecules have earned more attention than heme. We have spent years refining the art and science of heme production. This past decade has seen a wild surge of interest in heme, especially from the food innovation sector. Early on, our process focused on a consistent, reliable hemoprotein that supports manufacturers producing plant-based meats, nutritional fortifiers, and specialty food colors. Controlling every step of the process gives us foresight to anticipate changes in demand, supply, and application requirements. Precision matters, but underneath the analytics, we use our hands, eyes, and decades of troubleshooting experience to deliver a product that meets the expectations of the world's strictest clients.

    The Distinction of Manufacturer Craftsmanship

    Every kilogram of heme leaving our facility reflects our commitment to traceable sourcing, steady processing routines, and real talk with equipment, not just instruments. We do not buy from a bulk trader or repackage for markups. We harvest, ferment, extract, and concentrate. Raw materials matter for heme purity, so we select only consistent, vetted starting products. Each batch faces real-world tests—solubility, color, iron content, odor. These details make a difference in food applications where even subtle changes go straight to taste panels and quality screens. Inspection includes checking for off flavors, spectrometry for the color range, and simple baking or frying tests for those using heme as a flavor contributor.

    The choice to specialize in heme production led us to invest in fermentation technologies, protein separation, and purification systems tailored for heme’s unique characteristics. Our approach draws on human oversight as much as automated monitoring. On the factory floor, technicians smell, taste, and observe. Bulk handling and safety routines stem from learning through years on site, not just trending regulatory advice. The way the concentrate behaves under high-shear mixing or low-pH stabilization comes from working the recipes in actual scale, under production pressures and deadlines.

    What Makes Our Heme Stand Out

    Our heme, labeled primarily as Heme-X99, is the direct result of continuous feedback with end-users—food engineers, culinary scientists, and R&D labs who need more than a box of powder or a tank of liquid. The requirements we answer can be as subtle as a protein’s flow in a mixing vat or the stability of pigment during thermal processing. Food-grade heme plays several roles. In plant-based meats, our clients have told us how heme increases umami, enhances aroma, and bridges the gap in raw-to-cooked transition. Texture and color matter, but so do logistics—our product offers a standardized, high iron content suitable for direct addition or further formulation, without causing clumping or precipitation issues.

    Differences between food-grade heme and commodity hemoproteins go deeper than a certificate of analysis. Our product achieves higher color stability in the finished food, less metallic aftertaste, and greater miscibility with plant proteins. This comes from fermentation and downstream cleaning that filter out free iron and unwanted byproducts, leaving a smoother flavor impact. Clients in nutritional supplement business look for a heme source that delivers bioavailable iron without gastrointestinal irritation or difficult flavor. We tune the process so the residual byproducts stay well below detection. Heme-X99 is not just about ‘iron in a bag’, but a reliable performer under heat, processing stress, and real-world shelf conditions.

    Tuning Heme to Real-World Demands

    Production of heme is not just about matching a spec sheet. Each year, we respond to subtle shifts in what clients ask for. Sometimes a customer wants a stronger red to add to a new sausage recipe. Another demands precise flavor tone for a meat analog destined to be fried, grilled, or pressure-cooked. We adjust fermentation conditions, monitor substrate feeding rates, and sometimes tweak the purification scheme to meet these evolving needs. Years ago, one application partner approached us with a protein mix that kept curdling during scale-up despite passing every small-lot test. Our engineers spent weeks in the trial kitchen, working batch by batch, to tease out the micro-level interaction until we dialed in the right heme concentrate that solved the issue. Recipes only exist on paper until they hit the blender or fryer—this is something we have learned over hundreds of projects.

    Other manufacturers might import a ready-made powder, sometimes even a partially hydrolyzed one from animal blood, and then relabel it. We tinker directly in house, avoiding broad-sweep production practices. Some claim “plant-derived” heme by blending yeast-expressed pigment with large amounts of food coloring—practices we avoid in favor of traceable, fermentation-based purity. Keeping everything on site means we adjust for subtle batch-to-batch variation. From a regulatory perspective, we keep a transparent process, ready to answer auditors at a moment’s notice, because we run our own lab and keep data open to scrutiny. This means less ambiguity if a downstream customer faces recall, less risk for product launches, and easy retraction in unexpected events.

    Specification: More Than Numbers

    What does a specification actually mean to someone frying burgers or extruding nuggets made of soy and pea protein? For us, specs serve as checkpoints, but usage always reveals the truth. Heme-X99 contains a stable hemoprotein concentration, iron content above industry minimums (outperforming many animal-based heme extracts), and a lowest-possible microbiological load. The difference to our clients lies in how heme blends and holds up during production, especially after pasteurization or retort. We do not just test for minimum standards, but run accelerated shelf trials, cook stress panels, and pH cycling. This approach drives meaningful specs rather than paper compliance.

    Several of our clients have commented on the absence of metallic tang—a taste problem prominent in poorly-purified heme products. By optimizing our chromatography and taking time for proper pH balancing, we sidestep these negatives. Our batches also demonstrate rapid dissolution, helping busy facilities avoid clogging or uneven distribution in high-volume food processing lines. We rely on both instrument readouts and hands-on trials—sometimes a veteran operator’s feedback on a batch tells us more about usability than any chromatograph. That’s the backbone of a manufacturer’s practice.

    Application Insights: Experience at Scale

    Customers from the food innovation space often underestimate the impact of small changes in heme’s formulation. Plant-based burgers get most of the press, but we’ve supplied heme to partners making sausages, dumplings, jerky, fortified broths, and even medical foods. Texture, color retention during storage, and interaction with legume or mycelium proteins keep our process focused on consistency. We pay attention to how the product feels in the user’s hands—fine flow, no lumping, smooth incorporation in high-velocity mixers. New applications keep popping up: meat analog breakfast patties in North America require longer holding times; instant noodle flavoring packets need a specific absorption profile; European snacks companies demand heme that resists color loss in shelf-stable packaging. Real feedback from these partners shapes how we tweak both process and sampling.

    Back in 2021, we worked closely with a ready-meal company that hit repeated fails during test marketing of a new chickpea-based cutlet. Labs kept picking up faint off-notes and color fade after rethermalization. We spent weeks cycling batches through retort and freeze-thaw cycles to pinpoint the root cause. The fix was not a broad-spectrum additive, but refining our cut-point in the heme purification. This experience set new internal benchmarks—each time our heme enters a recipe trial, we track not only immediate color or iron content but how the product rides out pasteurization, freezing, and reheating, at every checkpoint along the chain.

    Beyond Standard Heme Products

    Many talk about 'sustainable protein' like a marketing buzzword, but practical sustainability means eliminating batch waste, ensuring high yields, and working toward lower energy consumption per unit of heme produced. Our facility reclaims process water, manages fermentation side streams, and minimizes packaging wherever possible. Working directly with fermentation partners for yeast, plant, and certain animal-free sources, we spent years selecting strains that deliver purity without excessive byproducts. This journey was driven not by regulatory fashion, but by hands-on awareness—reducing odor issues, lowering off-note risks, minimizing protein denaturation.

    Comparing heme from different sources proves enlightening. Animal-sourced hemoproteins—especially poorly controlled hydrolysates—often fall short in clarity, flavor, and allergen management. Some synthetic pigments labeled as ‘heme analogs’ miss the micronutrient value, and rarely can they duplicate heme’s sensory depth. Our focus remains on traceable, high-purity fermentation products with defined protein and iron levels. Every improvement, from particle size tweaks to solubility trials, grows from actual customer pain points, not theoretical specs.

    Reliability Born from Consistency

    Reliable supply chains start at the source—not on a spreadsheet, but inside the building. Owning every step, from fermentation through to packaging, allows us to manage unexpected raw supply delays, maintain planned maintenance routines, and work directly with logistics to withstand market shocks. During global disruptions, food companies need to count not just on monthly shipments but on technical support and backup. Our logistics partners communicate directly with us; if a pallet is late or a drum needs relabeling, we solve it ourselves, not by waiting for a third-party go-between.

    Heme presents environmental challenges. Iron stains equipment, off-spec protein batches can spoil quickly, and some applications test the limits of product shelf life or stability during final processing. Instead of running away from these realities, we document them, build controls, and invest in operator training. Spotting a developing problem early—discoloration, separation, unusual smell—prevents issues that could unwind months of recipe work. Experience teaches that specification sheets tell only half the story. Reliability grows from the routine checks, the honest post-mortem on failed pilot runs, and the willingness to adjust.

    Addressing Safety and Regulatory Demands

    Food safety rests on real vigilance and clear processes. Heme requires special handling—our plant keeps separate equipment for animal-based and fermentation-based streams, and tracks every lot back to its source. Facility audits run twice as often as required. Staff training emphasizes process hygiene, rapid isolation of any suspect batch, and rigorous allergen management. Our data stays open for client review, making life easier for customers navigating regulatory registration or product launches in new countries. If problems turn up in a finished food, we provide clear recall support and batch trace tools, since we design the whole tracking system in house.

    The growing regulatory spotlight on novel food proteins has raised expectations—from trace metal controls to allergen labeling. Our routine covers these issues early in process development. We never rely solely on documentation; regular spot checks in routine and off-hours catch problems before they reach a client’s QA desk. Building relationships with regulatory agents, not just submitting forms by email, earns us more trust and fewer surprises. Clients rely on us for product registrations and customs documentation, since we keep all analyses on site, ready for instant access or real-time verification.

    Future Directions: Putting Experience to Work

    The next phase for heme manufacturing will be defined by transparency and continual quality elevation. Raw material transparency, lower carbon footprint production, and greater collaboration with food designers form our roadmap. Newer applications in infant nutrition, specialized medical foods, and premium prepared meals are pushing us to further refine our purification and powderization processes. Each new challenge—abnormal color drift, trace impurity incidents, customer-driven demand for completely animal-free substrates—keeps us invested in evolving. We treat every feedback, complaint, or request for trial material as a source of learning, not just transaction. The ability to adapt, not just declare compliance, keeps our facility and our team relevant in a fast-changing world.

    Many companies jump into novel protein markets as short-term traders, looking for easy markup or quick resale. We are different. Consistent heme production draws on an ongoing relationship between plant, lab, and end user. Every insight we gain—each shelved project, successful launch, or batch failure—enriches the product. Our conversations with engineers, cooks, and safety managers feed nightly into the operation, informing everything from the way we manage fermentation to the adjustments we make in packing lines.

    Manufacturing heme is about solving problems well before they go downstream. It means catching an off-spec before it travels across an ocean, spotting a process error in time to salvage a batch, and counseling clients on real-world application troubleshooting. After years of working every corner of the facility, we believe trust grows from the steady hand at the source: the people who handle, test, and stand behind the product every step of the way.

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