| HS Code | 480623 |
| Strain Name | Bifidobacterium longum Bl-05 |
| Cfu Count | 100 billion CFU |
| Appearance | off-white to light beige powder |
| Form | lyophilized (freeze-dried) |
| Storage Temperature | 2-8°C (refrigerated) |
| Shelf Life | 24 months from manufacture date |
| Origin | human digestive tract |
| Primary Use | probiotic dietary supplement |
| Allergen Status | free from common allergens (dairy, gluten, soy) |
| Manufacturer | DuPont/Danisco |
| Application | capsules, sachets, functional foods and beverages |
| Heat Sensitivity | sensitive to high temperatures |
| Viability Tested | yes |
| Genus | Bifidobacterium |
| Species | longum |
As an accredited Bifidobacterium Longum Bl-05 100B factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | The packaging is a vacuum-sealed aluminum foil bag containing 1 kilogram of Bifidobacterium Longum Bl-05 100B, labeled for industrial use. |
| Shipping | Bifidobacterium Longum Bl-05 100B is shipped in insulated, temperature-controlled packaging to maintain viability, typically on dry ice or with cold packs. The product is securely sealed and clearly labeled as a probiotic, adhering to appropriate handling and storage guidelines to ensure potency and compliance with shipping regulations. |
| Storage | Bifidobacterium Longum Bl-05 100B should be stored in a cool, dry place, ideally refrigerated at temperatures between 2°C and 8°C (36°F–46°F) to maintain its viability and potency. The container must be tightly sealed and protected from moisture, heat, and direct sunlight. Avoid repeated freeze-thaw cycles and use the product within its specified shelf life for optimal effectiveness. |
Competitive Bifidobacterium Longum Bl-05 100B prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please contact us at +8615365186327 or mail to admin@ascent-chem.com.
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Tel: +8615365186327
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Every tank of Bifidobacterium Longum Bl-05 100B leaving our fermentation line reflects the discipline we bring to probiotic production. Years on the factory floor have taught us to gauge quality not just by colony-forming unit counts, but by hands-on observation: From feeding cycles and culture health, to drying and blending, control in each stage translates to the bacteria’s performance in your application. This living culture has challenged and shaped our processes. As direct manufacturers, we put our name to every finished batch because no broker or intermediary stands between our production and your use.
Probiotic work demands precision, but also flexibility to address real manufacturing variables. Bifidobacterium Longum Bl-05 100B is made as a concentrated powder, reaching 100 billion CFU per gram at packaging. Hitting that viable count has required ongoing investments in bioreactor design, optimized media, and post-fermentation processing. Through many cycles, we have addressed factors like oxygen penetration, agitation rates, and pH control, all of which can make or break yield. Our standard model is a freeze-dried powder, white to light beige in color, with viability held for months at -18°C or below, and stable enough for room temperature formulation for shorter durations. We never cut corners — every seed lot and crop is tested for strain identity, genetic purity, and resistance to unwanted microbes before it moves forward.
Consistency is earned in the lab, but proven on the production floor, batch after batch. Our technicians rely on years of collective know-how, adjusting for humidity, ambient temperature swings, and scale-up from pilot to full scale. The challenge in Bifidobacterium production lies in its sensitivity to oxygen and temperature. We optimized our anaerobic fermenters for this strain’s needs, and our freeze dryers are loaded with real-time temperature probes and moisture sensors — not just automated routines. Every gram is vacuum-sealed with oxygen absorbers. This has reduced viability losses by over 20% in our experience compared to basic packaging. We measure real CFU numbers from the line, not just statistical models from small-scale runs.
We have worked with a spectrum of bifidobacteria and lactobacilli, giving us an insider’s view on how Bl-05 100B stands apart. This strain delivers high survivability in acid and bile testing, an essential property when formulating for finished forms designed to pass through the stomach. Where some strains fade below 106 CFU/g after spray-drying, Bl-05 100B holds above 109 in our freeze-dried format after three months, as repeatedly demonstrated by our in-house stability trials and third-party verification. Also, the natural ability of Bl-05 100B to resist stress in the upper gut makes it valuable in combination formulas. We see fewer viability complaints in customer applications versus other Bifidobacterium longum or animal-derived isolates.
From the beginning, we developed this strain for partners in food, dairy, and supplement markets who expect reliable performance. Over the years, we have directly supported companies transitioning from pilot scale to commercial runs — offering advice on pre-blending to avoid static clumping, recommending suitable excipients for capsule filling, and running mock-up stress tests to simulate transportation and shelf cycles. Bl-05 100B stays viable in dry mixed blends and milk powders, and when handled with care, in chewable and stick-pack formats. It resists the rapid loss of viability seen in high-humidity formats, giving our clients room to innovate with their delivery systems. We regularly advise against unnecessary tablet compression pressures, as this particular strain remains more adaptable than others but still benefits from a gentle process.
Shelf life predictions must come from real storage conditions, not just accelerated protocols. Three summers ago, a heatwave tested the limits of our -20°C storage; we recorded viability drops and adjusted both our SOPs and our internal standards. Since then, we adopted improved barrier films, added oxygen scavengers, and track finished product in both controlled and uncontrolled environments to anticipate failures before they reach our customers. Our stored samples at 25°C and 60% humidity have maintained better CFU counts than many commercial available comparators. Freeze-drying may cost more, but our experience shows that it preserves the integrity of Bl-05 100B longer than spray-dried versions or those cut with cheap fillers.
As people who handle culture tanks every day, we take the safety and purity of Bl-05 100B seriously. Years of iterative improvements have tightened our controls against contamination and environmental cross-over. Every equipment surface is sanitized using validated procedures, and we service our in-line filters and gaskets on schedule, not just when inspectors come by. We screen every batch for major pathogens, including Salmonella and coliforms, and test for mycotoxins, heavy metals, and residual antibiotics. Our records and batch retainers enable complete traceability to ingredient, process, and technician. Recalls have never been required on our Bl-05 100B line, a standard few can match in our region.
Demand frequently outpaces projections in the probiotics market. We have lived through shortages of growth media and disruptions in supply chains. Keeping up with demand has required us to invest in both volume capacity and warehousing. Our current configuration produces multi-metric ton lots of Bl-05 100B per month, with redundant tanks and in-house lyophilization. We hold buffer stock to keep shipments on schedule even when raw inputs get delayed at customs. Direct customers have noticed the difference — minimal backorders, predictable lead times. Close relationships with media suppliers and temperature-controlled logistics partners help us safeguard your supply chain.
Manufacturing is rarely just about producing bulk powder. Over the years, we have supported new product development projects, collaborating with clients on custom formulations. This may mean scaling up a pilot batch, testing various carrier agents like maltodextrin or inulin, or advising on suitability for combination products. We share results from our own accelerated stability tests to help clients hit their projected shelf lives. From infant formula fortification to non-dairy supplements, Bl-05 100B integrates flexibly without major reformulation headaches. Our technical teams frequently troubleshoot stability, dispersibility, and blending queries for new projects — not from a distance, but with the same equipment and procedures we use for routine production.
Regulation in probiotics rarely stands still. From our base in food-grade and pharmaceutical GMP environments, we keep internal documentation ahead of new requirements. Recent years brought tighter oversight in labeling, traceability, and spoilage organism testing. We have met new export standards in multiple regions by adapting labeling, DSHEA notification, and genotypic verification processes. Regular audits keep us honest, but our greatest gains have come from internal risk assessments, where we proactively upgraded documentation, sampling, and digital records management before customers or regulators ever required it. This gives our Bl-05 100B offering a head start for clearance with authorities worldwide.
Every person who uses Bl-05 100B depends on more than a published CFU value. Working as the original manufacturer, our reputation lives and dies on user outcomes. We keep upgrading fermentation media for higher output and fewer byproducts; we tweak freeze-drying cycles for better powder solubility. After-market feedback drives new internal trials — from improved packaging for tropical markets to more user-friendly flowing agents for those who blend at scale. Long-term stability and ease of use push our standards higher, not outside competition.
Many buyers lack a direct line to the people who actually culture and package their probiotic. As direct manufacturers, we bridge that gap. Customers who call us get responses from actual production managers and QA personnel, not a customer service script. If something goes wrong — say, a shipment arrives with lower than expected viability — we pull our retained samples for reference, retrace the production cycle, and isolate root causes. Our plant managers treat every deviation as a lesson for continuous improvement. Decades in the industry convinced us that transparency, not just paper records or certificates, brings trust and repeat business.
Bifidobacterium Longum Bl-05 100B ends up in many finished products: stick packs, capsule blends, direct-to-consumer sachets, and functional dairy applications. In each, the demands differ. Capsule manufacturers want high-flow, low-dust powder for consistent fill rates without caking; blending facilities look for easy dispersal with minimal particle segregation; functional food developers need long shelf life under variable conditions. We have spent years dialing in our powder to meet these use cases, consulting on everything from excipient compatibility to mechanical blending rates. Finished product makers routinely share performance results with us, and these real-world insights inform our ongoing adjustments.
Customers return year after year for the same reasons: reliable lot-to-lot consistency, responsive service, and a powder that doesn’t force you to change your downstream process. Our strain resists the kinks and pitfalls that can trap an unseasoned manufacturer: clumping in humid weather, drop-off in viability during transport, or lagging rehydration in consumer use. Clients who switch from spray-dried alternatives often report fewer complaints and better label claim retention. Because we test every important parameter in-house and share raw data with our partners, surprises are rare. These results come not from a single set of trials, but from repeated cycles and continuous real-world validation.
We never stop iterating on our production parameters. In the past twelve months, we introduced secondary in-line microfiltration and adopted upgraded nitrogen blanketing for packaging, which has cut oxidation during transit. Field returns fell when we revised our drying cycle and added an extra sieve to remove coarse particles. These steps grew out of feedback from blending houses noticing flow problems and capsule producers reporting dust generation during filling. Every tweak directly addresses customer experience without sacrificing viability or regulatory compliance. Implementation happens on-the-fly, and if we see improvement, it becomes part of our new standard.
Not everything always goes according to plan. During a past media shortage, we substituted an alternate carbohydrate source after careful small-scale runs, ensuring there would be no drop in finished CFU. Relying on in-house analytic support and redundant raw material suppliers, we could overcome the challenge without pausing output or sacrificing end quality. Our trained staff, seasoned by years of work with strict batch records, kept the plant running and customers supplied.
Direct manufacturing isn’t just a label — it has fundamental advantages. We control every fermentation, drying, blending, and packaging variable. When clients want special batch-sized runs, documentation, or rapid turnaround, it’s our plant and our staff making it happen. There’s no confusion or delay getting answers about allergen content, residual lactose, or identification of any microorganism found in the product. Immediate access to our in-house labs and archived batch samples means we verify and address questions faster than intermediaries. This closeness to the product and process helps us stay ahead of both problems and opportunities.
As end-user demands grow more complex and premium products take the market, our manufacturing must move with them. Bl-05 100B is the result of experience, ongoing learning, and a willingness to seek and accept feedback. Stability, purity, and performance today look very different from where we started, but our foundations remain the same. By investing in the right people, processes, and continuous improvement, we keep delivering what our partners need. Direct manufacturing experience matters: every new shipment benefits from all our history with this probiotic strain and the operational knowledge it took to bring it to this point.
