|
HS Code |
425308 |
| Chemical Name | 2-Chlorobutane |
| Chemical Formula | C4H9Cl |
| Molar Mass | 92.57 g/mol |
| Cas Number | 78-86-4 |
| Appearance | Colorless liquid |
| Density | 0.866 g/cm³ |
| Boiling Point | 91–92 °C |
| Melting Point | -137 °C |
| Refractive Index | 1.4063 |
| Solubility In Water | Insoluble |
| Vapor Pressure | 157 mmHg at 25 °C |
| Flash Point | 2 °C |
| Odor | Sweet, chloroform-like |
As an accredited 2-Chlorobutane factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | A 500 mL amber glass bottle with a secure screw cap, labeled "2-Chlorobutane, 500 mL", hazard symbols, and handling instructions. |
| Shipping | 2-Chlorobutane should be shipped in tightly sealed containers, clearly labeled, and compliant with hazardous materials regulations. It must be transported as a flammable liquid (UN No. 1127) and stored away from heat, sparks, and incompatible substances. Ensure proper ventilation during transit and follow local and international shipping guidelines. |
| Storage | 2-Chlorobutane should be stored in a cool, dry, and well-ventilated area, away from sources of ignition, heat, and direct sunlight. Store in tightly sealed containers made of compatible materials. Keep away from oxidizing agents, strong acids, and bases. Proper labeling is essential, and spill containment measures should be in place. Store in accordance with all applicable chemical storage regulations. |
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Purity 98%: 2-Chlorobutane with 98% purity is used in organic synthesis laboratories, where high purity ensures selective reaction pathways and improved product yield. Boiling Point 68°C: 2-Chlorobutane with a boiling point of 68°C is used in distillation experiments, where its defined volatility enables efficient solvent separation processes. Reagent Grade: 2-Chlorobutane of reagent grade quality is used in Grignard reaction preparations, where reliable consistency enhances reproducibility and accuracy of experimental results. Density 0.87 g/cm³: 2-Chlorobutane at a density of 0.87 g/cm³ is used in phase separation protocols, where density compatibility with other solvents optimizes extraction efficiency. Stability Temperature 25°C: 2-Chlorobutane with stability at 25°C is used in storage and transport applications, where chemical integrity is maintained over extended periods. Low Moisture Content: 2-Chlorobutane with low moisture content is used in pharmaceutical intermediate synthesis, where minimized hydrolysis promotes target compound purity. Enantiomeric Purity 99%: 2-Chlorobutane of 99% enantiomeric purity is used in chiral synthesis processes, where high stereochemical control produces desired enantiomers. Colorless Liquid Form: 2-Chlorobutane in colorless liquid form is used in analytical research, where the absence of impurities enables accurate spectroscopic analysis. |
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2-Chlorobutane, a name you might spot on a drum in a university lab or hear in a classroom, sits at an interesting crossroads between industry, education, and innovation. It’s a clear, colorless liquid with a noticeable odor, easy to distinguish once you’ve spent some time working hands-on with chemicals. The backbone of its value comes from a simple arrangement: four carbons in a chain, one chlorine snuggled onto the second carbon, and enough volatility to keep chemists alert. While folks often chase newer, flashier molecules, 2-Chlorobutane has anchored organic chemistry for decades, thanks to its classic reactivity and the lessons it can teach about molecular behavior.
Back in my university days, nothing hammered home substitution or elimination reactions quicker than running through an SN2 experiment with 2-Chlorobutane. The molecule’s simplicity lets you watch science in real time — it nudges students and professionals to dig deeper into the basics. Sometimes you find that straightforward molecules, not just the complex ones, reveal the most about how chemistry ticks.
Chemicals live by their purity, and 2-Chlorobutane is no exception. Laboratory-grade batches often reach a purity of 99% or higher. You can tell each quality level by its documentation, usually measured by gas chromatography. That’s not just for bragging rights—impurities throw a wrench in reactions, sometimes giving odd-smelling surprises or stalling yields at scale.
Density, boiling point, and refractive index—these specifics tell you how the molecule behaves outside a book’s page. 2-Chlorobutane boils around 68°C, a figure that’s more than trivia for anyone distilling it or designing a reaction with temperature constraints. Its moderate density makes it easy to separate from water in workups, a short-lived victory in otherwise long synthetic protocols. Flammability can’t be ignored if you’ve ever worked in a tightly packed fume hood; experience teaches you to stay cautious with volatile chemicals, no matter how routine they seem on paper.
It’s easy to think that a simple molecule has limited use, but 2-Chlorobutane pops up in every nook of organic chemistry. Industry needs it for building bigger things, whether that’s pharmaceuticals, agrochemicals, or specialty polymers. In the hands of an undergraduate, it’s a jumping-off point for reaction mechanism studies. I’ve seen production teams rely on it for Grignard reagent synthesis, where that chlorine atom holds the key to transforming a straightforward alkane into something much greater down the line.
Training labs gravitate toward 2-Chlorobutane because its reactions don’t typically run violently or unpredictably. Instead, it helps establish strong lab habits, teaching students to measure, transfer, and monitor with real-world stakes. Unlike chemicals that disappear into diagrams, this one leaves traces on benchtops, glassware, and memory.
Put 2-Chlorobutane side-by-side with something like 1-chlorobutane, and you notice differences beyond just the numbers. Reactivity changes because the chlorine shifts from one spot to another. That simple move transforms reactivity and reaction outcomes. For synthesis, this means new paths, different products, and distinct lessons from each isomer. I remember troubleshooting a reaction, only to learn later that a small mix-up between 1-chloro and 2-chlorobutane explained months of confusing data. Details matter, and this molecule is proof.
Unlike more heavily functionalized chemicals, 2-Chlorobutane isn’t overwhelmed with substituents. That leaves it right in the sweet spot—active enough to participate in diverse transformations, simple enough to avoid confusion among new learners.
Chemical manufacturing sometimes feels worlds away from the academic lab, but 2-Chlorobutane acts as a bridge. Its routes to synthesis are classic: direct chlorination of butane or substitution on butanol substrates. This process requires tight control. Over-chlorination can produce side-products, which can gum up machinery and create headaches for cleanup. Working in a plant setting, the safety officer’s reminders about handling chlorinated volatiles always come back at the smell of 2-Chlorobutane.
Industrially, companies use this molecule not as a finished product, but as a building block. It might leave the factory as part of a batch meant for further transformation—converted into alcohols, amines, or wilder structures by skilled synthetic chemists downstream. Recalling a project where 2-Chlorobutane fed into a custom surfactant, I saw firsthand how a straightforward molecule could enable products that end up in detergents, cleaners, and specialized coatings.
Anyone who works in chemistry long enough develops a respect for safety. 2-Chlorobutane, with its volatility and moderate toxicity, isn’t something you splash around. Prolonged skin contact brings irritation, and vapor exposure quickly lights up headaches and dizziness. Even in well-ventilated spaces, working with open containers can feel risky. The distinct, halogenated odor lingers—a sure sign that masks and fume hoods should stay in use.
I’ve watched colleagues grow lax after years of routine handling, only to get a reminder from a spattered glove or a whiff of vapor. With incidents come policy adjustments: better personal protective equipment, tighter protocols, regular safety seminars. No matter how simple the chemistry, those practices stay non-negotiable when chlorinated solvents are around.
Governments keep a watchful eye on chemicals like 2-Chlorobutane. In the United States, the Environmental Protection Agency lists it as a hazardous air pollutant. That means production, storage, and disposal all happen under a modern microscope. Factories must invest in capture systems to limit emissions, and waste handling includes regular audits and documentation. From Europe to Asia, similar rules pop up, built on shared lessons from past spills and exposures.
On the regulatory frontlines, I’ve witnessed how changing legislation prompts manufacturers to update facilities. Sometimes that means expensive scrubbers or new approaches to solvent recovery. In research settings, labs keep detailed inventory lists and follow disposal procedures that reflect both legal requirements and a sense of ethical responsibility. Even if paperwork slows research down, the peace of mind and environmental protection make it worthwhile.
Supply chains in chemistry run lean, and disruptions ripple quickly. Hurricane season or a hiccup at a key plant and suddenly 2-Chlorobutane can become hard to find. I remember waiting weeks for a shipment, with every delay slowing students’ projects or halting pilot runs at scale. Those episodes force labs and factories alike to maintain inventory buffers and nurture relationships with more than one supplier.
Pricing also swings with broader energy and feedstock costs. As oil prices rise or environmental controls tighten, the cost of getting pure 2-Chlorobutane climbs. Tracking these trends gives procurement teams opportunities to negotiate contracts or seek alternative reagents for essential reactions. Building redundancy—never relying on a single source—became a lesson that saved my group from disaster more than once.
You never forget your entry into the world of practical chemistry. For many, 2-Chlorobutane is the first “real” chemical they encounter beyond water and ethanol. It forms part of the foundation for countless undergrad curriculums, right alongside acetone and hexane. Many students learn to set up reflux apparati, handle extractions, and interpret NMR spectra through experiments built on this molecule.
Academic instructors rely on it as a way to sprinkle practical experience with theoretical concepts. After students finish their first substitution or elimination, the molecule becomes less mysterious and more approachable. From my time TA’ing lab courses, I recall how it fostered confidence and curiosity, encouraging students to troubleshoot, hypothesize, and learn from mistakes.
Proper storage of flammable, volatile solvents like 2-Chlorobutane occupies a prominent place in any lab manager’s mental checklist. Flammable cabinets, grounded containers, and regular inventory audits become second nature. Given its tendency to escape closed vessels, investing in high-quality seals isn’t luxury, it’s necessity. I’ve seen entire shelves reorganized to keep incompatible chemicals apart: one misplaced jug causes more than inconvenience when chlorinated volatiles join forces with strong bases or oxidizers.
Routine maintenance—even labeling habits—directly affect performance and safety. After a single close call where ambiguous handwriting led to mistaken identity, our lab instituted double-verification for every container transfer. The lesson stuck: clarity trumps convenience, especially as the years tick by and memories fade.
Disposal practices for 2-Chlorobutane tell the story of chemistry’s evolving green conscience. In the past, solvents went down drains or into open-air unsalvageable waste. As knowledge grew on persistent organic pollutants, those habits shifted. Nowadays, labs collect and categorize spent chemicals, sending halogenated waste off for incineration in specialized facilities. Recycling or re-distillation of spent solvent, once a niche practice, has gained foothold as environmental regulations bite harder.
In practice, that means more paperwork, higher costs, but far cleaner outcomes for air, water, and soil. Working with responsible disposal services, I’ve found that transparency in reporting and a willingness to adopt best practices builds reputation as much as it protects the environment. Everyone wins when responsibility isn’t an afterthought.
While textbooks cover the major transformations—substitutions, eliminations, syntheses—real-world chemists often take 2-Chlorobutane off the beaten track. Specialty surfactants, custom intermediates for dyes, or pilot-scale projects in new material science often start with this simple chemical. Sometimes, research leads to findings that bring new life to an old molecule, as in asymmetric catalysis or green chemistry protocols that reduce hazardous byproducts.
Seeing 2-Chlorobutane play a part in unexpected places always reminds me that chemistry thrives on reuse and discovery. Molecules often outpace initial expectations, finding roles in new sectors as needs evolve. This flexibility—paired with the molecule’s reliability—keeps it in rotation through cycles of innovation.
Not every chlorinated hydrocarbon serves the same role. Compared to chloroform or carbon tetrachloride, 2-Chlorobutane offers a blend of reactivity and safety measures that fit better with modern sustainability expectations. Its lower density, moderate hazard profile, and straightforward synthesis reduce some logistical headaches. While handling regulations remain strict, the risk profile isn’t as severe as its heavier peers.
Within the butane family, minor changes in structure prompt major differences in physical and chemical properties. Simple swaps in the chlorine position cause shifts in boiling points and reaction pathways. Those who try to substitute from 1-chlorobutane to 2-chlorobutane in precision syntheses see firsthand that shortcuts rarely work—planning and testing rule the day.
Consistency underpins trust in any chemical purchase. With 2-Chlorobutane, purity isn’t just a number on a sheet—it means reproducible results, cleaner data, and fewer surprises. Reliable suppliers invest in robust analytical testing, providing certificates of analysis that back up their claims with detailed data. I’ve run GC analyses on incoming shipments, catching rare instances where contamination slipped through. Each incident reaffirmed the value of regular QC checks, both from the supplier and the end user.
Quality concerns stretch beyond purity. Packaging integrity, shelf-life management, and handling recommendations all play into a seamless process flow. Temperature fluctuations during shipping can affect stability, so monitoring and logging conditions help prevent headaches down the road. Trust but verify applies everywhere: receiving chemists know the importance of running quick incoming tests before diving into large-scale syntheses.
Working with chlorinated hydrocarbons like 2-Chlorobutane entails navigating a mix of human error, regulatory hurdles, and environmental risks. Each challenge pushes chemistry to innovate: greener chlorination methods, less hazardous substitutes, and digital tracking for stricter compliance.
Real progress shows through incremental change. Labs adopt barcoding for inventory. Industry players invest in cleaner reactors and waste-capture technology. Academics meanwhile chase reactions with smaller environmental footprints—whether through phase-transfer catalysts or microwave-assisted protocols. These improvements stem from real-world experiences: spills, shortages, or lost samples all inspire clever fixes and tighter systems.
Behind every molecule, there’s more than formula or structure—there’s a community of practitioners working to keep science both safe and productive. With 2-Chlorobutane, the story isn’t just about supply and demand. It’s about mindful handling, smart process design, and years of shared knowledge culminating in safety, reliability, and fresh discoveries.
Teaching new generations to treat chlorinated solvents with care goes beyond rules on a poster. It comes from stories of near-misses, reminders during lab meetings, and daily routines built for protection rather than convenience. I’ve seen that nothing beats hands-on mentorship and willingness to adapt; watchful eyes and curiosity turn each new bottle into both a resource and a responsibility.
2-Chlorobutane’s reputation rests on its reliability and flexibility. Time after time, it demonstrates that simple structures can serve as workhorses both in industry and in learning environments. It’s not the most glamorous chemical, nor the most dangerous, but it fills a critical spot in the chemical landscape.
As the future of science points toward cleaner, safer, and more accountable practices, 2-Chlorobutane stands to gain new relevance through smarter processes and innovative utilization. Those who work with it, from undergraduates to process chemists, continue to add their voices and improvements to a long-running story. The molecule endures not just for what it is, but for how it keeps challenging, teaching, and evolving alongside those who rely on it.