|
HS Code |
535734 |
| Name | Thiophenol |
| Formula | C6H5SH |
| Molar Mass | 110.18 g/mol |
| Appearance | Colorless to pale yellow liquid |
| Odor | Unpleasant, garlic-like |
| Density | 1.07 g/cm³ |
| Melting Point | -16 °C |
| Boiling Point | 169 °C |
| Solubility In Water | Slightly soluble |
| Flash Point | 54 °C |
| Cas Number | 108-98-5 |
| Refractive Index | 1.626 |
| Vapor Pressure | 0.60 mmHg (25 °C) |
As an accredited Thiophenol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | Thiophenol is packaged in a 500 mL amber glass bottle with a secure cap, labeled with hazard warnings and safety instructions. |
| Shipping | Thiophenol is shipped in tightly sealed containers made from materials compatible with corrosive and volatile substances, typically amber glass bottles or steel drums. It is classified as a hazardous material, requiring proper labeling and handling in accordance with international transport regulations. Shipments must be protected from heat, ignition sources, and physical damage. |
| Storage | Thiophenol should be stored in a cool, dry, well-ventilated area away from sources of ignition and incompatible materials such as oxidizing agents and acids. Keep the container tightly closed and protected from light. Use containers made of materials compatible with thiophenol, such as glass or specific plastics. Ensure proper labeling and implement secondary containment to prevent accidental spills or leaks. |
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Purity 99%: Thiophenol Purity 99% is used in pharmaceutical intermediate synthesis, where high assay ensures superior yield and product consistency. Molecular Weight 110.18 g/mol: Thiophenol Molecular Weight 110.18 g/mol is used in polymer modification processes, where precise stoichiometry enables targeted macromolecular structure control. Melting Point -16°C: Thiophenol Melting Point -16°C is used in low-temperature chemical reactions, where liquid handling is maintained for efficient reaction kinetics. Stability Temperature 25°C: Thiophenol Stability Temperature 25°C is used in analytical reagent preparation, where shelf-life is extended under standard storage conditions. Viscosity Low: Thiophenol Viscosity Low is used in catalytic transformations, where rapid diffusion enhances conversion rates and process throughput. Refractive Index 1.62: Thiophenol Refractive Index 1.62 is used in optical polymer manufacturing, where precise optical properties are imparted to end products. Sulfur Content 29%: Thiophenol Sulfur Content 29% is used in rubber vulcanization accelerator synthesis, where sulfur availability optimizes cross-linking reactions. |
Competitive Thiophenol prices that fit your budget—flexible terms and customized quotes for every order.
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After years working hands-on in the chemical industry, our team has learned that success with thiophenol starts long before the molecule ever leaves the reactor. So many conversations in the specialty chemical market focus on packaging, distribution, or tying up logistics. In our plant, our attention stays on the reaction kettle, the distillation columns, and the line-by-line records from every batch. Reliable thiophenol production comes down to precision and care at every step, from handling raw benzene derivatives to distilling the colorless liquid that experienced chemists recognize by its distinctive odor and reactivity.
People approach us for thiophenol because they want a partner who understands the practical demands of custom synthesis, pharmaceutical manufacturing, and agrochemical innovation. The expectations for purity aren’t just words on a technical data sheet. Lab researchers and pilot plant engineers need a consistent material—one that doesn’t surprise them with unexpected impurities or performance issues. We learned early on that the smallest inconsistency in our process can throw off downstream applications, particularly when a customer pushes for reactions that require tight control over sulfur reactivity and high assay results. Our thiophenol achieves an assay consistently above 99%, backed by regular GC analysis, not sporadic lab samples or spot checks.
Specifying thiophenol means understanding the real differences between a lab-grade bottle and a substance meant for scalable production. For example, we focus on limiting acidic impurities and managing color levels throughout production. Even a hint of yellow discoloration signals the start of oxidation or the presence of unwanted byproducts. This, in turn, can impact sulfonation yields or even early-stage pharmaceutical synthesis where a single contaminant affects the whole pathway. All of this matters more than paperwork. We continually invest in analytical technology—not just for marketing, but so downstream problems never trace back to our drum or tank. When we bottle thiophenol, we verify low moisture, minimal residue on evaporation, and clarity that persists in storage. Much of this comes from hard-won technique: tight control during distillation, choice of glass-lined reactors, attention to inerting protocols, and working with supply partners who keep the feedstock quality high.
Model types stem from user demand. Over time, customers who need thiophenol for aromatic substitution reactions in pharmaceuticals or complex agrochemicals ask for slightly different specs—sometimes a minimum water content, sometimes extra attention to trace metals or storage stability. We’ve learned not to overpromise on universal batches. Instead, we focus on clear technical dialog, openly sharing what we see in analytical runs, and listening when a customer notes a problem doesn’t appear on a standard COA but makes a difference in their process.
Manufacturing thiophenol isn’t a casual task. Sulfur compounds have their quirks, and with phenyl mercaptan, you get an aromatics plant challenge with the added attention that thiols demand. We engineer every process to reduce the risk of off-quality material from the start. This means disciplined raw material QC, skilled operators who track every shift, and physical safeguards to limit contamination. Our operators know to take action if a batch shows signs of oxidation, color change, or even a faint variation in odor. Working with thiophenol, every kilogram that crosses the line represents weeks of careful preparation—from filtration before bottling, to inerting storage tanks, to handling customer-specific filling requirements. Our culture rewards those who notice small, practical issues and act before they turn into headaches.
The right packaging matters more than most upstream customers realize. A minor reaction in a poorly sealed drum causes discoloration or even pressure buildup. We use drums with high-integrity seals, always under inert gas. For specialty clients, we adapt process lines to fill in glass bottles or smaller ampoules, preventing oxidized fragments from creeping in. We’ve learned, sometimes the hard way, that packaging choices shape customer confidence as much as the purity figure. Years ago, a customer’s analytical lab picked up a spike in disulfides that we later traced to heat cycling in warehouse transport—after that, we invested in climate-stable storage, not just warehouse space. These small changes make our product a steady part of countless downstream protocols, not an unpredictable wild card.
The core uses of thiophenol highlight why customers and manufacturers put so much emphasis on purity and reactivity. The molecule serves as an essential building block for many thioethers, intermediates, and ligands in both pharmaceuticals and agrochemicals. A key feature of thiophenol is the strong nucleophilicity of its sulfur atom, which enables efficient aromatic substitution and coupling reactions. These processes thrive on a reliable, well-characterized reagent. Chemists look for a clear, colorless material that delivers predictable yields batch-to-batch. Our clients report that with an inferior grade, reactions stall or produce tars that complicate purification. Consistent product keeps reactions running smoothly in both laboratory and more industrial conditions.
Medicinal chemistry teams return for our thiophenol because it gives them confidence in synthetic steps where a single contaminant or a slightly elevated water content ruins a fragile intermediate. In the crop science industry, where volumes can reach drums instead of flasks, attention swings to reproducibility, storage life, and handling risks. Our production setup lets us meet both needs, whether a kilogram for an exploratory campaign or a metric ton for a scale-up run. The learning curve with thiophenol is real—sulfur chemistry doesn’t always behave, and regulatory pressures keep growing. We keep one eye on emerging requirements, like reduced halide and metal content, so our product stays aligned with shifts in both pharma and ag.
Over time, we’ve had customers who ran into trouble using material supplied elsewhere: reactions yielding unexpected byproducts, storage drums developing faint color over weeks, or material failing Karl Fischer moisture checks. Some of our earliest quality improvements came not from a customer request, but from our own failures in trial runs—seeing a trace contaminant sabotage a pilot process, or watching a supposedly stable drum develop cloudiness after a summer in non-cooled storage. Each setback brings lessons that feed directly into our workflow. These adjustments—better inerting, adjusting distillation rates, minimizing air exposure, and checking for storage temperature swings—build confidence among process chemists at the bench and purchasing managers balancing cost with risk.
Our technical team keeps open lines with users, especially those who use custom protocols or high-throughput designs. Many times, process engineers ask us for detailed analytical summaries, repeated GC-MS or HPLC reports, or assurance that no new side products have appeared across batches. We don’t treat these conversations as a burden. They help us keep internal standards truly high, not just “acceptable to most.” Other times, a customer will call mid-campaign suspecting an off-odour or an unexpected TLC spot—they want to know if something in the batch could be causing the issue. Our lab tracks every shipment, correlating customer feedback with our records, correcting and learning without waiting for formal complaints. Open, responsive communication keeps us at the front of the field, not just meeting, but anticipating tougher demands ahead.
There’s plenty of thiophenol, technically speaking, on the global market. The real difference comes in reliable, traceable quality and in-depth support. Larger traders or resellers can move drums quickly, but most don’t invest in production controls or batch-level documentation. Over time, that results in small, creeping inconsistencies. By running every step from raw benzene derivative to final filling, our team keeps details in focus. We control not only the chemical process, but the context—the temperature, storage life, bottling precautions, and direct transport partnerships. Every flask or drum traces back to a specific batch, with analytical data to back up claims.
Another distinction is our willingness to adapt. Some years, regulatory requirements tighten; in others, a new synthetic process calls for extra stringency on breakdown products. Our facility adapts—whether through deeper drying steps, doubly sealed packaging, or fast turnaround for small lots. If a client says their NMR spectrum picks up an unassigned peak, we don’t just point to our standard documentation. We’ll investigate, compare notes across recent lots, and share our own NMR, GC, and Karl Fischer logs. By producing in-house, not reselling third-party material, we offer direct input into troubleshooting. This makes all the difference when teams face deadlines or process uncertainties.
Working directly with the material, we spot trends and avoid overpromising. For example, in the early days, we saw some users focus only on sulfur content and ignore aromatic impurities, which would disrupt downstream steps. Today, our analytics go well beyond basic assay—monitoring for inhibitors, color, trace water, and residual metals. We know firsthand how one weak control can affect an entire run. Our own trial reactors serve as early warnings; any anomaly triggers a full review, not just a “pass/fail” score. The real measure is whether the customer consistently meets their process benchmarks, not whether we check a minimum box.
Handling sulfur chemicals, especially volatile thiols, can complicate everyday plant operations. Over-oxidation creates unwanted byproducts. Poor inerting leads to early color development. Unstable warehouse conditions leave customers with questionable material. From the start, we decided not to cut corners. Our plant relies on segregated lines, dedicated reactor systems, and rigorous vapor-phase controls. For high-purity batches, we extend column distillation, add secondary filtration, and manage containers under continuous nitrogen cover.
In cases where a customer’s process reacts badly to even low-level residues, we adjust our cleaning protocols, double-check analytical results, and discuss whether custom packaging will help. Sometimes, the choice of a certain drum type, or more frequent independent analysis, provides enough assurance. Open discussion helps both sides avoid surprises. From the practical side, being the manufacturer gives us leeway to innovate without bottlenecking through a global distributor’s narrow requirements. This matters when timelines are tight and applications grow more sensitive.
Our reputation comes from years of investing in relationships rather than chasing short-term sales. Chemists who tested our thiophenol in early discovery campaigns have kept us informed as they scale up those same molecules for process development. Their feedback tells us about pain points far sooner than we’d learn from a distant sales report. Whenever we supply to a new field—specialty polymers, electronics intermediates, or custom synthesis—our technical staff listens for unexpected issues, cross-checks feedback with our own logs, and adapts protocols to keep pace with evolving needs.
The difference shows up clearly in repeat business and word-of-mouth references. When downstream chemists see reliable reaction yields, easy workups, and stable storage with our thiophenol, they speak up. We don’t take their confidence for granted. Maintaining high quality means constantly checking our own work, investigating every anomaly, and staying ahead of both regulatory shifts and market demand. Our team prides itself on transparency—offering detailed analytical reports, tracking batches, and owning up quickly when something goes wrong. This kind of direct connection only happens through years of close technical collaboration, not anonymous catalog sales.
Demand for thiophenol continues to rise, driven by shifts in crop science, pharmaceuticals, and material science. Each segment comes with distinct challenges. Regulatory agencies ask for ever-narrower limits on residual solvents, metals, and aromatic byproducts. End-users develop new coupling reactions that push traditional purity controls. Meeting these needs calls for agility, not just bigger reactors. Our plant invests regularly in upgrading both process hardware and analytical capabilities—expanding GC-MS and NMR capacity, automating moisture checks, and keeping detailed trend records on every lot. Data flows directly from shop floor technicians to senior chemists, who use real production experience to interpret the smallest deviations before they become process risks.
Looking to the future, our approach remains tied to fundamentals: disciplined chemical control, transparent dialogue, attention to real-use cases, and a refusal to cut corners on safety or quality. As new users enter the market—whether for thioether linkers in peptide synthesis or selective reduction steps in complex syntheses—we remain ready to answer technical questions, support process improvement, or customize packing and specification protocols. We believe true reliability comes from understanding the details—batch to batch, shipment to shipment—and being ready, always, to adapt as our partners’ needs evolve.
In the daily work of chemical manufacturing, reputation builds from small successes and hard-learned lessons. Our thiophenol stands apart not from a single feature or a marketing push, but from decades handling the challenges, risks, and quirks of sulfur chemistry. From our operators who track every batch, to our chemists who double check purity, our focus stays on delivering a material that process engineers, pharmacists, and researchers can trust. With each bottle, drum, or tanker, we bring not just a reagent, but a commitment built on real-world experience—a partnership for teams who need more than a line in a catalog. Real results come from paying attention, being accountable, and responding directly to what matters at the bench or in the plant. Our thiophenol is the sum of all these pieces, produced by people who know what’s at stake.