Products

Tert-Butyl Chloride

    • Product Name: Tert-Butyl Chloride
    • Alias: tert-butyl chloride
    • Einecs: 203-696-6
    • Mininmum Order: 1 g
    • Factroy Site: Yudu County, Ganzhou, Jiangxi, China
    • Price Inquiry: admin@ascent-chem.com
    • Manufacturer: Ascent Petrochem Holdings Co., Limited
    • CONTACT NOW
    Specifications

    HS Code

    432409

    Name Tert-Butyl Chloride
    Chemical Formula C4H9Cl
    Molar Mass 92.57 g/mol
    Appearance Colorless liquid
    Density 0.857 g/cm3
    Melting Point -23 °C
    Boiling Point 51 °C
    Solubility In Water Slightly soluble
    Vapor Pressure 400 mmHg (20 °C)
    Flash Point -10 °C
    Cas Number 507-20-0

    As an accredited Tert-Butyl Chloride factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Tert-Butyl Chloride is supplied in a 500 mL amber glass bottle with a secure screw cap and hazard labeling.
    Shipping Tert-Butyl Chloride should be shipped in tightly sealed, corrosion-resistant containers, away from incompatible materials such as strong oxidizers. It is classified as a flammable and irritant liquid; therefore, shipping must comply with relevant hazardous material regulations. Ensure containers are properly labeled, and transport in a cool, well-ventilated vehicle.
    Storage Tert-Butyl chloride should be stored in a cool, dry, well-ventilated area away from heat, sparks, open flames, and direct sunlight. Keep the container tightly closed and properly labeled. Store separately from strong oxidizers, acids, and bases to prevent hazardous reactions. Use corrosion-resistant containers, and avoid prolonged exposure to air and moisture to maintain chemical stability.
    Application of Tert-Butyl Chloride

    Applications of Tert-Butyl Chloride in Industrial Manufacturing

    As a primary manufacturer of tert-butyl chloride, we serve diverse chemical sectors where this compound acts as a crucial intermediate. The following application scenarios detail our material’s industrial use, with process insights and regulatory context specific to each downstream segment.

    1. Agrochemical Synthesis: Herbicide and Pesticide Production

    In agrochemical manufacturing, tert-butyl chloride serves as an alkylating agent for producing various substituted aromatic and aliphatic herbicides, including phenoxy acids and sulfonylureas. Producers adhere to stringent purity and trace impurity standards to comply with regional and global agrochemical safety regulations, particularly when formulating crop-protection compounds destined for regulated markets. The loading percentage within reaction systems typically depends on target molecule design and active ingredient yield optimization, requiring technical adjustment for each formulation. Chlorination and subsequent substitution steps integrate tert-butyl chloride early in multistep syntheses, directly impacting active substance yield and byproduct profiles. End-use formulations shipped include selective herbicides and insecticides for commercial-scale agriculture applications.

    Industry compliance standards

    • FAO/WHO Pesticide Specifications
    • REACH Registration (EU)
    • US EPA Registration Guidelines (40 CFR Part 158)
    • China GB 2763 Maximum Residue Limits

    Typical usage ratio

    • Stoichiometric ratios from 0.8:1 to 1.2:1 relative to nucleophile, based on active ingredient structure; manufacturers adjust batch size to reaction kinetics and degree of chlorination required.

    Downstream process integration

    • Charged in alkylation or halogen exchange reactors at the initial stage, associated with base-facilitated substitution (SN1 for tertiary moieties).

    Final product types

    • Selectively substituted phenoxy herbicides
    • Triazine and sulfonylurea pesticides
    • Custom agricultural formulations for field trials and commercial deployment

    2. Pharmaceutical Intermediate Manufacturing

    The chemical introduces tert-butyl groups during synthesis of key pharmaceutical intermediates, often protecting hydroxyl or amine functionalities in regulated API production. GMP-compliant plants integrate tert-butyl chloride within reaction vessels fitted for hazardous gas management and controlled addition. Content in protective group chemistry varies depending upon the ratio needed for stepwise deprotection and minimization of residual impurities, with precise molar equivalents determined by throughput and downstream purification steps. Drug master file holders validate the use of tert-butyl chloride for patented or generic process routes, with batch and impurity data recorded in compliance with pharmacopeial monographs. Main downstream products include intermediates for cardiovascular, anti-inflammatory, and CNS APIs.

    Industry compliance standards

    • ICH Q7 GMP for Active Pharmaceutical Ingredients
    • USP/NF and Ph. Eur. monographs on process impurities
    • US FDA 21 CFR Parts 210/211 for finished APIs
    • EU GMP Annex 8 (API Synthesis Controls)

    Typical usage ratio

    • Commonly 1.0–1.5 molar equivalents per functional group, tuned for minimal excess; batch-specific documentation required for process validation and impurity profiling.

    Downstream process integration

    • Applied in the protection of alcohols, amines, or acids via tert-butyl ether/ester/amide formation during intermediate stages; fully removed or converted by terminal deprotection before API crystallization.

    Final product types

    • Pharmaceutical intermediates for antihypertensive drugs
    • Precursors for NSAIDs and CNS active pharmaceuticals
    • Custom building blocks for contract R&D syntheses

    3. Fragrance Ingredient and Flavor Additive Manufacturing

    Tert-butyl chloride finds direct use as an alkylating agent in the industrial-scale synthesis of fragrance and food flavoring molecules, especially for producing tert-butylated aromatic esters and ethers with enhanced olfactory characteristics and stability. Regulatory compliance focuses on traceability, batch consistency, and food or cosmetic safety standards set by international authorities. Industrial perfumers specify dosage levels depending on desired sensorial intensity and seat in multi-component compositions, and adjust for substrate reactivity and volatility constraints. Production facilities integrate tert-butyl chloride at the initial step of Friedel–Crafts alkylation or etherification, setting the stage for subsequent distillation and blending lines. The resulting compounds are deployed by major flavor and fragrance houses across fine fragrance, personal care, and food markets.

    Industry compliance standards

    • IFRA Standards (International Fragrance Association)
    • US FDA 21 CFR Part 172 (Food Additives Permitted for Direct Addition to Food)
    • EU Regulation (EC) No 1334/2008 (Flavourings and Certain Food Ingredients)
    • ISO 9235:2013 (Aromatic Raw Materials for Use in and as Food Flavours)

    Typical usage ratio

    • 0.3–1.1 molar equivalents per aromatic substrate, depending on substrate activity for the Friedel–Crafts reaction; downstream blending standardizes fragrance intensity to ppm/ppb levels per formulation guidelines.

    Downstream process integration

    • Added to batch reactors for alkylating phenols or anisoles; reacts under Lewis acid catalysis before purification and formulation into end-use flavor or fragrance bases.

    Final product types

    • Tert-butylated anisoles and phenols for perfumery
    • Flavor esters and ethers for beverages, confectionery, and dairy goods
    • Top notes in fine fragrances and complex scent compositions for household and personal care

    4. Polymer Additive and Fine Chemical Synthesis

    The application in polymer additive production revolves around the manufacture of tert-butylated phenolic antioxidants and UV stabilizers intended for inclusion in plastic, rubber, and lubricating systems. This compound forms a core feedstock in the alkylation of polyhydric phenols, creating molecules with highly effective radical-trapping activity. Major plants operate under the chemical management frameworks of downstream industries, documenting precise reactant ratios and output specifications to achieve high-yield conversions and robust dispersion in various matrixes. Reactor dosing is typically governed by designed substitution patterns—single or multiple tert-butyl insertions—so operators select loadings based on targeted molecular architecture. Downstream value chains incorporate these additives via masterbatch blending or direct incorporation into the compounding process. Final plastic and elastomeric goods meet performance and regulatory safety requirements for target markets.

    Industry compliance standards

    • REACH Annex XVII (EU Chem. Safety for Additives)
    • US FDA 21 CFR 177.2600 (Rubber Articles Intended for Repeated Use)
    • China RoHS 2.0 for Polymer Additives
    • UL Yellow Card Certification for Polymeric Materials

    Typical usage ratio

    • 0.95–1.3 equivalents of tert-butyl chloride per phenolic site, modifiable for mono- or di-tert-butylation; adjustment based on required antioxidant strength.

    Downstream process integration

    • Charged into phenol alkylation reactors, operating sequentially or in parallel with other alkylating agents; followed by isolation and incorporation into antioxidant or stabilizer masterbatches.

    Final product types

    • Hindered phenolic antioxidants for polyolefin and elastomer compounding
    • Light stabilizer systems for exterior automotive and packaging polymers
    • Performance films and engineered plastic components with extended oxidative stability

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    Certification & Compliance
    More Introduction

    Tert-Butyl Chloride—A Core Ingredient Forged by Careful Engineering

    What Sets Manufactured Tert-Butyl Chloride Apart

    Tert-Butyl chloride, known within the lab and the plant for its sharp, distinct odour and volatility, takes a trusted place in the world of chemical manufacturing. Here on the production floor, where the buzz of compressors and the hiss of valves fill the air, this compound emerges from a synthesis of raw feedstock and skilled oversight. Forging tert-butyl chloride is as much about watching subtle pressure swings and tweaking reaction rates as it is following any formula on a paper. Over years of working in the reactor hall and behind the control screens, we’ve developed instincts—an immediate sense for batch quality, an ear for the hiss that tells you purity is on track.

    Our typical product delivers a GC Assay above 99%. Packed and sealed under dry nitrogen, you can count on stability even through long-haul transport and handling. Turning out clear, water-white product on a repeatable basis only happens through strict process control, temperature balance, and genuine appreciation for details that don’t always make it into data sheets.

    The Chemist’s View: Where Tert-Butyl Chloride Finds Its Purpose

    Most of our output flows straight to other manufacturers, where it often disappears into the backbone of pharmaceuticals, agrochemicals, and flotation agents. In the pharmaceutical world, it grabs the attention of route developers who need a ready source of tert-butyl as a protective group or for constructing linkers. In synthesis, using tert-butyl chloride as an alkylating agent gives consistent results thanks to its reactivity profile—less aggressive than methyl chloride but with sufficient power to close a reaction on time. Many of our customers working in specialty polymers opt for tert-butyl chloride to introduce branching points, creating advanced resins and PETG copolymers with targeted performance qualities.

    In halide-exchange reactions, the temperature tolerance of tert-butyl chloride stands out. It doesn’t evaporate before the job is done, and its boiling point allows for easier separation at the back end of a process flush. Unlike isopropyl or methyl chloride, which flash off faster, tert-butyl chloride remains in solution until deliberate removal, narrowing down batch-to-batch variance.

    How Manufacturing Practice Defines the Final Product

    Long before the first kilogram leaves our plant, the process steps reflect about two decades of continuous improvement. We dedicated effort toward minimizing by-products, refining stripping columns to keep out traces of hydrochloric acid, and updating distillation equipment to reduce thermal decomposition. Anyone who’s handled poor quality tert-butyl chloride recognizes decomposition by its faint yellow tinge and strong burn on inhalation—a result such as this doesn’t leave our site.

    Each batch goes through full trending. Our operators check acid content, water presence, and color before release. If water creeps above 0.01%, we know it’s time to recalibrate the final drier. This vigilance means customers see consistent, reliable quality, whether they order a single drum or fill a bulk tanker.

    We take pride in traceability. For any given lot, pinpointing feedstock source, process dates, and applied controls is a matter of routine. That means genuine assurance during audits—a customer or regulator can follow any drum back to the exact shift and operator. Our focus runs well beyond passing regulatory minimums; it's about integrity and standing behind every shipment.

    The Real-World Differences from Blends and Lower-Grade Material

    We spend time in the field and in the plant, seeing how our product and others perform side by side. Customer labs often send us sample bottles of competitors' material—some with faint color, excess acidity or unwanted sulphur notes picked up from old process lines. These negatives can translate to lost yield, downstream equipment fouling, or rework that slows production. Our experience tells us that even impurities at the parts-per-million level can trigger off-odors or catalytic deactivation, especially in scale-up processes where tolerance for error gets thin.

    Some resellers blend offspec streams to meet generic requirements, but careful users know the difference. A clean, single-origin tert-butyl chloride cuts batch failures and downstream headaches. By focusing on process consistency from the start, we avoid surprises later—a lesson earned by solving the real-world mysteries that show up in customer reactors.

    We do not recover or recycle bulk streams from used silanes or spent petrochemical cuts. Our line builds from fresh feedstock, with each reaction tuned to maximize selectivity. Control over raw input keeps halides and residual hydrocarbons at levels well below industry standards. This is not always the case with distributors, who sometimes blend or relabel material from uncertain sources.

    Process Safety and Environmental Outlook

    On the plant floor, handling tert-butyl chloride safely means more than fitting a warning label. We design our reactors and transfer lines to contain every litre—from corrosion-resistant alloy construction on tanks and transfer pipes, down to pressure relief valves set for the gas tightness that prevents fugitive emissions. Our plant runs negative pressure systems to catch accidental leaks before they reach ambient air. In addition, experienced staff receive direct training in handling water-reactive and volatile materials, with annual drills for emergency shutdowns and spill containment.

    Venting and purging operations run through activated carbon traps and neutralization towers. We monitor every output for hydrochloric acid traces, making certain our neighbours—and our own staff—work in safe, healthy conditions. Any spent product or by-product does not leave our site untreated; all effluent goes through acid scrubbing and neutralization with careful testing before permitted release.

    We also keep our carbon footprint and chemical waste output under constant review. Investment in more efficient heat exchangers and process controls has resulted in a real reduction in greenhouse gas loading, noted in our annual inspections by local authorities.

    Meeting Standards Without Compromise

    Year after year, regulations surrounding halogenated hydrocarbons tighten. We keep pace by testing beyond required specification sheets—screening for stabilizers, aromatics, and retained metals not yet covered by law. By establishing our own tighter acceptance criteria, customers gain confidence for product registration in the EU, US, and Asian markets. Auditors are welcome in our plant, and we expect challenging questions.

    Tert-butyl chloride isn’t only about technical properties; it’s about confidence gained from repeated, reproducible results. Our regular customers—especially those in pharma and electronics—depend on us to guarantee that minute details in composition line up lot to lot. For firms facing qualification or process integration, knowing that a key intermediate remains unchanged is as important as a fast, dependable delivery schedule.

    Application Highlights from the Factory Floor

    One of our largest end-users produces high-value agrochem intermediates. In their processes, tert-butyl chloride acts as an alkylating agent to introduce branching that transforms physical performance and regulatory approval status. Because of known pressure points in batch reactors, their engineers prefer our product for its lack of water and organic acid—qualities that avoid costly shutdowns for pump replacement and filter changes.

    Another customer in the electronics sector leverages tert-butyl chloride to functionalize silicon surfaces. They specify our grade precisely because slippage—resulting from contaminants—is simply not tolerable on high-value wafers, where each surface defect translates to yield loss. Any trace of by-product can cause adhesion failure and cost thousands in rework time.

    Experienced synthetic chemists favor tert-butyl chloride due to its ready conversion to tert-butanol or other derivatives needed in organic chemistry. Easy storage and low metal content assure dependable storability and reactivity in multi-step procedures. Some applications, such as the preparation of t-butyl ethers or the introduction of t-butyl moieties into pharmaceuticals, succeed not only because of the inherent reactivity but also thanks to guaranteed absence of color bodies, which indicate oxidative degradation and can trigger downstream coloration.

    Drawing the Line: Real Manufacturing Choices Matter

    Manufacturing a seemingly simple product like tert-butyl chloride never comes down to just following a prescribed set of steps. Hidden variables—subtle acid concentrations, invisible trace metals, the reliability of our nitrogen inerting—all play roles far more important than data sheets usually reveal. Each decision, whether it’s setting a drier for one hour longer or rebuilding a distillation tray, cascades to affect the rest of a customer’s daily production.

    Global supply chains see frequent turbulence. Yet, with in-house production and raw materials sourced under long-term contracts, we keep output steady. Our resilience comes from working close to the process—with lives invested in chemistries and equipment that won’t tolerate shortcuts. Issues get solved at the source, before they become field failures.

    Customers sometimes ask why our product maintains a slight pricing premium over generic or reblended stock. Those who have faced recurring process stoppages, unexpected color changes, or downstream contamination incidents quickly realize that dependable manufacturing brings a return on investment that raw price lists ignore. A drum’s value lies as much in what it doesn’t include—unwanted by-products, residual acids, non-volatile content—as in its base specification.

    The Real Payoff: Consistency, Reliability, and Technical Backing

    We maintain open technical channels with every long-term customer. If a formulation changes, we work alongside their technical teams, helping troubleshoot or optimize application conditions. Our technical staff routinely visit customer facilities, reviewing process performance and sharing best practices honed on our own production lines.

    Problems rarely arise in isolation. A trace contaminant problem revealed at a client lab can reflect back on slight process drift or unseasonal feedstock impurity. We treat every anomaly as a red flag worth investigation, not an excuse for batch replacements. This ongoing partnership frequently drives further product improvement—giving us data spanning thousands of runs, not just laboratory expectations.

    Relationship-building takes more than quarterly business reviews. By sharing process insights and working from experience, we support new product launches, process scale-ups, and even regulatory filings. Our application support means the customer gains more than material—they benefit from an ongoing dialogue across the value chain.

    Looking Forward: Where High-Quality Tert-Butyl Chloride Goes Next

    Demand for specialized intermediates shows no sign of slowing. Innovations in high-performance polymers, market shifts in the pharmaceutical sector, and new electronics materials all call for reliable access to building blocks like tert-butyl chloride.

    We plan for the long term, investing not just in equipment but in talent—the operators, engineers, and chemists whose hands and eyes define each batch. Automation complements, but does not replace, the expertise learned through decades at the bench and in the control room.

    Future improvements will come from tighter environmental controls, increased batch yields, and deeper partnerships down the chain. The push toward greater transparency in sourcing and lifecycle impacts matches our belief in traceable, responsibly manufactured materials.

    Our experience tells us that chemical manufacturing, at its best, rests on a foundation of responsibility and constant attention to detail—from the first step of synthesis to every drum shipped out the gate. By holding to these principles, we turn out tert-butyl chloride that end-users trust for purity, consistency, and safe handling, no matter how demanding the application grows.

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