Products

Sodium 4-Chloro-2-Nitrophenoxide

    • Product Name: Sodium 4-Chloro-2-Nitrophenoxide
    • Alias: Sodium 4-chloro-2-nitrophenolate
    • Einecs: 238-898-2
    • Mininmum Order: 1 g
    • Factroy Site: Yudu County, Ganzhou, Jiangxi, China
    • Price Inquiry: admin@ascent-chem.com
    • Manufacturer: Ascent Petrochem Holdings Co., Limited
    • CONTACT NOW
    Specifications

    HS Code

    135352

    Chemical Name Sodium 4-Chloro-2-Nitrophenoxide
    Molecular Formula C6H3ClNNaO3
    Molecular Weight 195.53 g/mol
    Appearance Yellow to orange powder
    Solubility In Water Soluble
    Melting Point Decomposes
    Cas Number 834-63-9
    Storage Conditions Store at room temperature, dry and away from light
    Synonyms Sodium 4-chloro-2-nitrophenolate
    Odor Odorless
    Ph Of Aqueous Solution Typically basic
    Stability Stable under recommended storage conditions
    Hazard Class Irritant

    As an accredited Sodium 4-Chloro-2-Nitrophenoxide factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing The chemical is packaged in a sealed, amber glass bottle containing 25 grams, labeled with hazard symbols, product name, and batch information.
    Shipping **Shipping Description for Sodium 4-Chloro-2-Nitrophenoxide:** Ship in accordance with local, national, and international regulations. Package in tightly sealed, chemically compatible containers with proper hazard labeling. Store away from incompatible substances. Protect from moisture and physical damage during transit. Ensure documentation includes chemical name, hazard classification, and emergency contact information. Handle by trained personnel only.
    Storage **Sodium 4-Chloro-2-Nitrophenoxide** should be stored in a tightly sealed container, protected from moisture and light. Keep it in a cool, dry, and well-ventilated area, away from incompatible substances such as acids, oxidizers, and reducing agents. Ensure the storage area is clearly labeled and access is restricted to trained personnel. Follow all local, state, and federal guidelines for chemical storage.
    Application of Sodium 4-Chloro-2-Nitrophenoxide

    Applications of Sodium 4-Chloro-2-Nitrophenoxide in Industrial Manufacturing

    Sodium 4-Chloro-2-Nitrophenoxide serves as a key intermediate in specialized chemical synthesis across multiple industrial sectors. Our manufacturing expertise supports diverse applications requiring strict process control, quality compliance, and reliable downstream integration.

    1. Synthesis of Pharmaceuticals (API Intermediates)

    Pharmaceutical producers utilize this compound during the manufacturing of certain veterinary and human APIs, notably for nitroaromatic drug scaffolds. It enters the production process at the nitro substitution stage, providing a controlled aromatic activation for further functionalization. Custom batch processes and validated cleaning procedures ensure strict impurity limits and batch traceability. Formulation teams adapt input quantities based on downstream yield and regulatory reporting requirements.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice (GMP) for Active Pharmaceutical Ingredients
    • European Pharmacopoeia Monograph 5.07
    • US FDA 21 CFR Part 211
    • EDQM CEP traceability protocols

    Typical usage ratio

    • 0.12 – 0.25 molar equivalents, precisely adjusted for desired API conversion and downstream purification efficiency

    Downstream process integration

    • Incorporated during aromatic nitration or halogenation step in multi-step synthesis
    • Isolated post-reaction by solvent crystallization or aqueous extraction depending on the API synthesis route
    • QC sampling for residual raw material as per established process protocols

    Final product types

    • Nitroaromatic APIs (e.g., veterinary anti-infectives)
    • Designated pharmaceutical intermediates for regulatory review
    • Crude and purified API output for downstream formulation

    2. Agroch emical Active Ingredient Manufacture

    Producers of crop protection chemicals employ this raw material as a ring-activated intermediate in the synthesis of selective herbicides and fungicides. The compound reacts at the aromatic core to introduce chloro and nitro moieties, supporting further derivatization for target molecule design. Downstream recipes require precise dosing to optimize active ingredient yield and minimize byproducts during large-scale continuous flow processing.

    Industry compliance standards

    • FAO/WHO Technical Specifications for Pesticides
    • ISO 9001 Quality Management for Agrochemical Production
    • REACH (EC No 1907/2006) Registration
    • Globally Harmonized System (GHS) for Hazard Communication

    Typical usage ratio

    • 9–14% by weight relative to total precursor charge, fine-tuned based on reaction scale and crop protection formulation batch size

    Downstream process integration

    • Direct charged in the aromatic substitution stage of batch or flow synthesis lines
    • Solvent-phase reactions monitored by in-line UV-Vis or HPLC analytics
    • Post-synthesis step transitions to neutralization, filtration, and formulation lines

    Final product types

    • Phenoxy-based agricultural herbicides
    • Pre-emergent weed-control agents
    • Registered technical-grade fungicide actives

    3. Dyes and Pigment Intermediate Production

    Industrial dye manufacturers use the material as a nucleophilic component for azo and nitro dye intermediate synthesis. Chemical technologists introduce it during controlled nitration and coupling stages to build chromophore structures with defined absorption spectra. Precision batch tracking, filtration, and solvent recovery govern production consistency and waste minimization in colorant manufacturing.

    Industry compliance standards

    • Oeko-Tex Standard 100 for Dye Substances
    • EU REACH Annex XVII (Restrictions on Certain Hazardous Substances)
    • ZDHC MRSL for Textiles
    • ISO 14001 Environmental Management

    Typical usage ratio

    • 3–7% by mass per dye precursor batch, adjustable based on target hue intensity and downstream dye application method (e.g., textile vs. leather)

    Downstream process integration

    • Introduced during azo coupling stage in dye intermediate synthesis
    • Participates in controlled base-promoted substitution reactions under aqueous or solvent conditions
    • Followed by isolation, washing, and fine-filtration to remove residual inorganic ions

    Final product types

    • Nitrophenol-based azo dyes
    • Specialty yellow and orange textile pigments
    • High-fastness colorants for wool and synthetic fibers

    4. Specialty Polymers and Resin Additives

    Polymer and resin formulators integrate this compound as a chain-modifying or side-group functionalizing intermediate in specialty thermosets. It imparts halogen and nitro functional groups that alter thermal and chemical resistance, particularly for electronic encapsulation resins and select engineering plastics. Meticulous process validation supports property consistency and byproduct management in volume manufacturing.

    Industry compliance standards

    • UL 94 Flammability Standard for Plastics
    • RoHS (2011/65/EU) Restrictions
    • ISO 9001:2015 for Polymer Compounds
    • ASTM D638 Tensile Properties for Plastics

    Typical usage ratio

    • 1.5–4.5 phr (parts per hundred resin) in final monomer mix; ratio optimized for targeted property profile and crosslinking degree

    Downstream process integration

    • Introduced during pre-polymerization or reactive extrusion with epoxy or phenolic resins
    • Integrated before thermal curing cycle to ensure homogenous modifier dispersion
    • Post-cure QA for residual monomer content and performance validation

    Final product types

    • Encapsulation resins for electronic modules
    • Crosslinking modified phenolic molding compounds
    • High-resistance engineering plastics with tailored chemical profiles

    5. Fine Chemical Building Blocks for Electronic Chemicals

    In microelectronic and specialty chemical sectors, this material functions as a targeting intermediate in the synthesis of custom etchants, photoresist additives, and functionalized coupling agents for advanced wafer processing. Tight control of purity (GC/HPLC) and batch segregation ensures predictable performance in semiconductor production lines, meeting cleanroom compatibility and impurity profile specifications.

    Industry compliance standards

    • SEMI C35 Standard for Bulk Chemicals
    • ISO 9001:2015 Certified Quality Systems
    • IPC-7711/7721 for Rework and Repair of Electronics
    • IECQ QC 080000 for Hazardous Substance Process Management

    Typical usage ratio

    • Trace to 2.8% by formulation, precisely calculated per custom etching or resist recipe and application test performance

    Downstream process integration

    • Added to initial reagent charges during precursor fabrication for photoresist or etchant
    • Subjected to staged purification to achieve ultra-low trace metallics and particulates
    • Batched for controlled dispensing into resist or etchant blending vessels

    Final product types

    • Photoresist adhesion promoters
    • High-specification semiconductor etchants
    • Functionalized coupling reagents for advanced packaging

    Free Quote

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    Certification & Compliance
    More Introduction

    Sodium 4-Chloro-2-Nitrophenoxide: Our Perspective from the Production Line

    In our years of manufacturing specialty chemicals, Sodium 4-Chloro-2-Nitrophenoxide stands out for reliability, consistency, and a track record of meeting demanding synthesis requirements. This compound, appearing in our product catalog under model S4C2NP-98, brings us direct feedback from customers working in pharmaceuticals, agrochemicals, and dyes. They value the carefully controlled chlorination and nitration steps we oversee, ensuring the structure’s integrity—both for safety and application effectiveness. Our team knows exactly what goes into its preparation, right down to the last filtration stage that keeps batch purity steady and free from processing residues.

    Manufacturing with Trust and Precision

    Production consistency doesn't come from chance. It’s about the way each batch runs on the same equipment, uses precisely weighed raw phenol derivatives, and receives our attention across every stirring interval and temperature adjustment. We stick to tried-and-true protocols: activating phenol, guiding the chlorination at exact temperature range, and finishing the nitration under closed monitoring. Any shortcut would show up fast as off-color, inconsistent particle behavior, or unwanted byproduct formation. Our internal QC team runs each batch for appearance, assay (HPLC and titration), moisture, and residual solvents.

    Over the years, we’ve learned just how easily trace impurities—say residual starting phenol, or halogenated byproducts—can affect downstream synthesis. We pour extensive effort into robust washing, isolation, and vacuum drying. Unlike products handled elsewhere, our Sodium 4-Chloro-2-Nitrophenoxide avoids yellow-brown discoloration or sticky consistency issues. Partners in the pharmaceutical intermediate sector especially want a product that dissolves cleanly, with no insoluble hush left at the bottom and no extra cost in further filtration steps. We set ourselves apart by delivering that.

    The Specifications That Matter Most

    Model S4C2NP-98 offers an assay consistently exceeding 98%, supported by low moisture and controlled particle size. Not every customer asks about heavy metals content, but since many use this material for further functional modification, we keep heavy metals to sub-ppm levels. Even trace inorganic residues or an unchecked pH range will cause coloring problems during dye synthesis, so we never overlook those points. Our specification runs tight for melting point, appearance (light yellow to off-white crystalline powder), and solubility in both water and typical organic solvents.

    On the plant floor, staff double-bag the finished material, watch for moisture ingress during handling, and avoid cross-contamination with other halonitro phenoxide intermediates—details that show up in decades of customer satisfaction. Our logistics team has developed packaging compatible with extended shipping in most climates, so the product arrives as pure as the day it left our drier.

    End Uses: Beyond the Specification Sheet

    Application drives our approach. Sodium 4-Chloro-2-Nitrophenoxide winds up as an intermediate in manufacturing complex molecules—those where positional selectivity matters and where trace inorganic salts cannot be tolerated. In the pharmaceutical segment, clients use it as a precursor for active compounds that demand exacting quality. Mol selectivity is the top concern—there’s no room for isomer confusion, so our controlled conditions make a difference here. Agrochemical producers transform it into functional molecules for crop protection, counting on our reproducible salt content and minimal organic residue.

    Customers in dye and pigment manufacturing praise the way our material behaves in high-temperature and high-alkali synthesis. The sodium salt form brings ease of handling compared to the free acid or neutral phenol, eliminating the time and hazard of base addition in their process. They often tell us that the consistency of color and yield starts with how clean they receive this intermediate. Unlike products imported through trader channels or resold in a broken chain of custody, we know exactly where each batch has been and what went into making it.

    How Our Approach Differs from Industry Norms

    Many manufacturers treat Sodium 4-Chloro-2-Nitrophenoxide as a commodity, aiming for volume and price over tight control. We take a different path by focusing on batch traceability and small-scale pilot runs that identify any deviation before it affects larger orders. Our production chemists have seen first-hand the difference that little things make—how a subtle shift in pH during washing, or a ten-minute dry air lag, can affect both color and downstream reactivity.

    We never process S4C2NP side-by-side with more reactive halide intermediates, even at the cost of slower turnaround time on the production line, because cross-reaction or trace halide contamination will render this high-purity material unsuitable for most end users. Our reputation rides on transparency and consultation with our clients, not just shipping products packed with generic specification certificates. Many in the market can supply a basic powder, but only those with a true manufacturer’s discipline can offer full documentation and on-demand technical support during scale-up or troubleshooting.

    Our technical team regularly assists users who need advice beyond the data sheet. Questions come in about solubilization in DMSO, scavenging unwanted ions, or troubleshooting a stubborn discoloration during late-stage synthesis. We open our production records, runtime batch numbers, and test logs to direct customers, so they see exactly what the material is and avoid surprises in their own labs.

    Supporting Customers in Real-World Conditions

    Harsh weather, delayed shipments, and new regulatory constraints all crop up in the real world. We’ve adapted packaging to limit moisture uptake across ocean transport and extreme temperatures. Double-sealing with inert liners can seem like overkill but pays off with consistent product quality at the destination. Some customers require additional purity certification, especially those exporting finished pharmaceuticals under ICH guidelines. We support their batch documentation needs, even if it means re-validating aspects of drying and analyzing retained samples.

    Unlike a distributor who might field questions from a distant supplier, we have direct control over the process and can answer specifics about wet vs. dry process residuals, vessel cleaning protocols, and the timeline between synthesis and final packing. All of this backs up what our customers trust us for: honest feedback, willingness to troubleshoot, and continual attention to regulatory changes.

    Innovating While Protecting Product Consistency

    We constantly review our upstream chemicals as regulation and raw material quality evolve. Recent years have seen international restrictions on certain nitrophenol precursors, and we source raw inputs with documented traceability. Our solvent management practices put a premium on reclaiming washes and neutralizing waste streams. These aren’t abstract “green chemistry” initiatives—it’s part of managing both cost and safety. Efforts to reduce waste do not compromise the final product. If process optimization ever threatens to change the physical profile or analytical data of Sodium 4-Chloro-2-Nitrophenoxide, we involve both internal and external labs for validation before approving the change.

    Entire supply chains get disrupted when a plant somewhere else cuts corners or changes process routes without warning. Our customers benefit from the way we plan for continuity. Backup inventory, alternative raw material sources, and close communication with those who order from us regularly keep things flowing. In our experience, it only takes one missed analysis or unnoticed raw material impurity to cascade into batches that fail in the customer’s high-value synthesis. We stop that chain before it starts through frequent process review and hands-on attention.

    Balancing Safety and Quality in Chemical Handling

    Our staff views Sodium 4-Chloro-2-Nitrophenoxide as more than a formula on a spec sheet. On the line, everyone wears protective gear suited to prevent inhalation or skin exposure, since the dust and particles pose both an irritant and a contamination risk. We regularly reinforce training for spill containment and correct waste flow management, not just to tick off an audit checklist but to safeguard long service health. This material doesn’t release persistent odors, but improper cleanup can spread residues that interfere down the line or discharge into the environment.

    Our QC team works shoulder-to-shoulder with plant operators, checking batch color, granularity, and analytical data long before the material arrives at final packing. We run independent sampling at every shift to avoid any “off-batch” surprises, keeping the aftermath off the customer’s plate. We see recurring business and high levels of trust from firms that have switched to our batches after trouble with variable impurities or “mystery” off-flavors from less rigorous sources.

    Market Comparison: What Sets Our Product Apart

    Talking to purchasing agents and process engineers, we hear again and again about complaints with bulk, unpacked Sodium 4-Chloro-2-Nitrophenoxide. It arrives in broken packages, caked lumps from moisture soak, and variable colors suggesting process shortcuts. Other manufacturers often substitute sodium salts of different nitro-chloro isomers or offer lower assay grades mixed with inert fillers, lowering the cost per ton but causing downstream purification headaches and reduced reaction yields.

    By controlling the entire process, we hold our quality steady. Repeat analysis by independent labs confirms lot-to-lot uniformity, in both organic and inorganic impurity content. End users tell us that they rarely lose time diagnosing product-origin issues, which lets them focus on their own innovation. In a crowded market where price pressures run high, our experience suggests the costs of repetitive purification, batch failures, and regulatory setbacks quickly outstrip any initial savings from a cut-rate source.

    Supporting Scale-Up and Regulatory Demands

    Research and production scale don’t always ask the same things. Small startup customers may need sample lots and hands-on support as they adjust their protocol to a new intermediate. Established pharmaceutical and agrochemical companies, working under increasingly tight regulatory bars, want supporting analytical records, Certificates of Analysis, and traceable batch histories. We maintain documented standards for microbial control, resonance spectroscopy, and trace element analysis to back up any compliance requirement.

    We recognize that every scale-up brings its own set of questions: stability in new solvents, long-term storage, reactivity with unanticipated trace metals, changes in local environmental laws. Our daily involvement in manufacture and packaging means we answer with our own data, not guesswork or relay from a middleman. We’ve supported partners through process revalidation, rapid replacement shipments during line failures, and on-site auditing visits. That level of engagement doesn’t happen without deep roots in the production process.

    Traceability, Documentation, and Lot Integrity

    Traceability isn’t a buzzword for us. Each batch of Sodium 4-Chloro-2-Nitrophenoxide comes from a discrete production window and receives its own set of production logs, analytical reports, and distribution records. This allows downstream users—which include major pharma producers and specialty dye houses—to follow every gram from synthesis through final shipment. If any end user experiences a problem, we use these records to investigate, re-test reserve samples, and work directly on remediation or improvement.

    Some customers worry about the potential for accidental off-spec material mixing during peak production. Our plant management enforces clear separation of product codes and zones, both for raw materials and finished goods. We’ve invested in logistical controls well beyond what’s required for general commodity production just to ensure this kind of traceability. These details keep our customers’ own quality systems running smoothly, and our long-term contracts reflect that trust.

    Cost, Quality, and Long-Term Partnership

    Industry pressure to drive down costs and increase output is real. Many suppliers look for shortcuts or ways to mask variable quality behind complex layered contracting. We’ve found the best route is clear communication, direct support, and delivering the same material every shipment. Our customers tend to stick with us once they experience the difference: fewer failed syntheses, less time wasted on troubleshooting, and a transparent path from purchase order to finished product.

    We’ve developed a business anchored on repeated reliability, rather than chasing each price wave or bulk market surge. This doesn’t always make us the cheapest upfront option. Still, our data shows the lowest total cost when factoring in production yield, worker safety, and the absence of unplanned downtime. Companies that partner for the long term build in resilience and technical capability far beyond what’s possible through arms-length spot purchases.

    Direct Feedback and Continuous Improvement

    We take customer feedback as the main source of improvements. Plant chemists often discuss daily manufacturing details with client R&D teams, comparing end-use results and remedying any reported inconsistencies. This feedback loop has led us to pioneer incremental process enhancements: adjusting crystallization rates for better filtration, varying dry time protocols to reduce caking, or introducing rapid batch release after a successful QC report.

    Direct communication and a willingness to support customers through process upsets, material transitions, and scale improvements have kept us in business through drastic industry swings and regulatory shifts. The partnership mindset cannot be matched by brokers who handle dozens of product lines with little control over source quality. We invite customer input not just at contract signing, but throughout every batch.

    Challenges and Solutions We Tackle

    Not every production run meets every target the first time. We record and analyze each deviation, whether in color, assay, or solubility, and use these lessons to guide future process changes. A key issue facing the industry is the growing expectation for zero impurity deviation as more regulations focus on trace chemicals and environmental impact.

    We’ve adapted our process, upgraded in-line filtration, and added extra solvent recycling stages to address even minute impurity spikes. Our experience reinforces that these investments pay off: production interruptions decrease, noise in end-user analytical data falls, and compliance recordkeeping gets easier. Open dialogue with client teams about what matters most—whether trace alkali content for crop-protection synthetics, or complete paperwork trails for pharma submissions—shapes the direction of our improvements.

    Strong feedback keeps us ahead of regulatory and technical challenges without chasing every short-term trend that sweeps the chemical market. Being the actual manufacturer means every decision, good or bad, lands directly at our door. We choose to embrace that responsibility.

    Final Thoughts on Real-World Impact

    Sodium 4-Chloro-2-Nitrophenoxide might seem just a chemical name on paper, but for us it’s part of a relationship built on continuous attention to detail and customer-led improvement. From the first raw material shipment to the last QC seal on a finished drum, every step impacts downstream success. We bring both technical rigor and open-door support to each order, no matter the size or market segment.

    End users who have struggled with unpredictable intermediates or unclear supply chains recognize quickly the value of a manufacturer-focused partnership. For us, manufacturing specialty chemicals remains a hands-on craft backed by reliable process, human expertise, and transparent support—all elements that keep customers coming back and advance the industries they serve.

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