| HS Code | 118798 |
| Chemical Name | O,O-Diethyl-O-(4-Nitrophenyl) Phosphorothioate |
| Synonyms | Parathion, Ethyl parathion, Parathion-ethyl |
| Cas Number | 56-38-2 |
| Molecular Formula | C10H14NO5PS |
| Molecular Weight | 291.26 |
| Appearance | Yellow to brown liquid or crystalline solid |
| Odor | Aromatic odor |
| Solubility | Slightly soluble in water; soluble in organic solvents such as acetone and ethanol |
| Melting Point | 6 °C |
| Boiling Point | 375 °C at 760 mmHg |
| Density | 1.263 g/cm3 at 25°C |
| Content | >4% |
| Storage Conditions | Store in a cool, dry, well-ventilated area away from incompatible substances |
| Stability | Stable under recommended storage conditions |
| Flash Point | 177 °C |
As an accredited O,O-Diethyl-O-(4-Nitrophenyl) Phosphorothioate [Content>4%] factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 500g of O,O-Diethyl-O-(4-Nitrophenyl) Phosphorothioate [Content>4%] supplied in a sealed, amber glass bottle with safety labeling. |
| Shipping | This chemical ships in compliance with hazardous materials regulations. It is securely packed in sealed, chemical-resistant containers, clearly labeled with hazard information. Shipping includes secondary containment, absorbent materials, and documentation for safe transport. Carriers with hazmat certification handle transit, ensuring adherence to safety protocols and minimizing risk during delivery. |
| Storage | O,O-Diethyl-O-(4-Nitrophenyl) Phosphorothioate [Content>4%] should be stored in a tightly sealed container, in a cool, dry, and well-ventilated area away from incompatible substances such as strong oxidizers and acids. Keep it away from sources of ignition, heat, and direct sunlight. Clearly label storage containers, follow all safety protocols, and restrict access to authorized personnel only. |
O,O-Diethyl-O-(4-Nitrophenyl) Phosphorothioate is a well-established active ingredient in organophosphate chemistry, with a proven track record across several heavy-regulated industrial sectors. Our high-purity formulation, manufactured under stringent quality management, finds its primary uses in downstream processes that require precision dosing, reliable integration within multistep synthesis, and consistent compliance with established industry and environmental norms. The following sections describe real-world industry applications, technical standards, process integration points, and finalized products derived through professional use of this compound.
The main industrial adoption of this compound occurs in the manufacture of organophosphate insecticides, serving as a phosphorus donor and intermediate during the synthesis of select crop protection agents. Agrochemical formulation plants use controlled dosage in multi-reactor batch processing to maintain active substance profiles in line with food safety residue limits and environmental exposure standards.
Industry compliance standards
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Veterinary pharmaceutical producers employ this compound for the on-site synthesis of antiectoparasitic agents, utilizing it as a phosphorothioate backbone source. This process forms the basis for the manufacture of certain topical animal health products, where consistently regulated batch outputs ensure animal safety and compliance with veterinary medicine guidelines.
Industry compliance standards
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Manufacturers serving public health vector control and industrial pest management sectors utilize this chemical for blending commercial-grade pest control concentrates. Its effectiveness against a defined spectrum of non-crop pests, along with established regulatory monitoring, makes it an ingredient of choice for product managers developing antifly and antimosquito residual sprays for institutional and industrial use.
Industry compliance standards
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The compound plays a critical role in specialty and fine chemical industries as a nucleophilic phosphorus reagent, participating in the synthesis of targeted phosphorus-based intermediates. This application supports the production of high-value specialty chemicals as well as process development in contract manufacturing organizations (CMOs) dealing with complex, multi-step syntheses.
Industry compliance standards
Typical usage ratio
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Competitive O,O-Diethyl-O-(4-Nitrophenyl) Phosphorothioate [Content>4%] prices that fit your budget—flexible terms and customized quotes for every order.
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Manufacturing chemicals often feels like an ongoing conversation with the realities of the field—what the market requires, what research points toward, what meets specific performance and compliance benchmarks. O,O-Diethyl-O-(4-Nitrophenyl) Phosphorothioate, content greater than 4%, models this perfectly. Over years of working closely with both formulation specialists and plant operators, we have shaped the way this product reaches our customers, responding to the unique demands that arise from actual application in the lab, field, and factory floor. There’s a reason why those familiar with its usage recognize its impact where highly targeted organophosphorus compounds matter.
Sourcing the right grade of raw materials marks the start of our process, not only for purity but also for reliability of supply. The diethyl and nitrophenyl precursors require careful screening to maintain minimal cross-contaminants, since even slight impurities change the product’s downstream performance. Our technical team reviews every batch, applying GC–MS checks coupled with classic titration, ensuring every drum shipped out measures up to our hard-earned standards. This kind of vigilance means when a customer opens a container from us, it matches their expectations batch after batch. Quite a few customers have remarked on how predictable our product’s behavior is compared to some bulk market alternatives.
Any manufacturer can list a product’s content percentage on a label, but achieving and maintaining above 4% by weight of active ingredient stands out for those who understand why the margin matters. In phosphorothioate chemistry, slight differences in purity make or break process yields, especially for those using it as an active intermediate. The content threshold above 4% is not just a regulatory check—it ties directly to the kind of finished results end users get. By using a tightly calibrated continuous-flow reactor setup, we minimize swing in content that can occur with larger, less controlled batch processes. Our facility runs repeated in-process HPLC analysis to catch any drift before it can reach packaging, a method that grew out of troubleshooting with partners who had previously seen erratic results from other suppliers.
Much of the demand for O,O-Diethyl-O-(4-Nitrophenyl) Phosphorothioate comes from sectors dealing with complex syntheses. For example, crop protection research teams lean on its selectivity in stepwise synthesis, while those in the analytical sector find it serves well as a standard reference material. Factory-level users appreciate the fact that our product mixes cleanly into their pre-existing blends, eliminating the need for extra drying or pre-treatment steps. This reduces downtime and lets operations flow smoothly from raw material receiving to final blend, a benefit we learned to emphasize after hearing from clients who struggled with blockages and sediment when dealing with lesser grades.
Another important application comes from institutions running large-scale screening programs. Consistency in compound content directly translates to consistency in test results, avoiding time wasted troubleshooting batch-to-batch variability. As one R&D director told us, swapping to our version let her team stop cross-validating every single shipment, freeing up staff to focus on actual innovations rather than back-end Q.C.
Chemical characteristics shape more than just reactivity—they affect every stage from transport to long-term storage. Our O,O-Diethyl-O-(4-Nitrophenyl) Phosphorothioate offers a distinct pale yellow crystalline appearance, which results from precise atmospheric and temperature controls during synthesis. Over time, we've found that adjusting cooling rates during crystallization tightens the lattice structure, giving improved shelf stability even in humid environments. Many large-scale users store drums for seasons at a time, so this feature extends usability and helps avoid waste caused by premature degradation.
Some competitors offer forms that clump or darken on extended storage. We tackled this by investing in inert gas blanketing at key steps, ensuring oxidative degradation stays minimal. Feedback from storage managers showed that this step sharply cut down on product returns, as barrels maintained their original composition even after months in the warehouse. Our routine batch-aging tests continue to guide protocol updates, making sure our product’s field stability matches the claims we make on paper.
Within our lineup, content always exceeds the 4% minimum, but we also provide modeled variations aligned with process requirements. For clients needing high-throughput processes, we offer an ultra-low residue variant where extraneous byproducts have been reduced even further. On the other hand, research groups sometimes prefer a standard grade with slightly broader impurity windows when cost is more important than absolute analytical clarity. We work directly with users to dial in the model that makes the most sense, thanks to a process that can rapidly switch feedstocks and process conditions without risking cross-batch contamination.
Some have asked whether higher content always means better. Experience suggests the answer depends on downstream chemistry. Too pure a material at times throws off blended formulations reliant on trace side-products as stabilizers. That’s where our flexibility pays off—we take calls directly from chemists and adjust the product to fit, rather than insisting on an off-the-shelf answer for every scenario.
One of the recurring issues in industry tends to be management of process waste and byproducts. Years of regulatory audits and site visits taught us early that producers need to take full responsibility for downstream environmental impact. To this end, we invested in closed-loop solvent recovery systems, reducing both the solvent residue in our finished goods and the total volume requiring post-process disposal. Our teams regularly review effluent streams, monitoring for any change in composition before regulatory authorities do—staying ahead avoids surprise shutdowns and keeps peace of mind for our partners.
We recognized a gulf in the market for product safety transparency as well. Some companies cherry-pick test results or skip over negative outcomes; we developed a policy of openly publishing detailed COAs and MSDSs with every shipment. Researchers, plant managers, and Q.C. leads rely on clear data, not vague assurances, so they trust what arrives matches their expectations. This policy results from many years sorting out misunderstandings stemming from incomplete paperwork—and it’s a lesson we keep front and center in every customer interaction.
Shipping hazardous chemicals remains a challenge worldwide, and authorities keep tightening rules on allowable transit conditions. We keep updated on every new regulation and have built out capabilities to offer both bulk and small-pack packaging, each with appropriate lining and venting systems, eliminating risk of off-gassing or package rupture during transport. Repeated annual certifications and unannounced logistics audits make sure our procedures live up to both international requirements and our internal benchmarks. Our logistics partners know our process and have adjusted their own systems in line with ours, saving both sides from the domino effect of delays and insurance claims that stem from inadequate packaging.
In the specialty phosphorus chemistry field, the devil is in the details. Many competing products aim to match nominal content yet fall short in batch uniformity. We have run comparative analyses with samples submitted by prospective clients, only to find significant variance in as-bought vs. as-tested purity and stability markers. This kind of inconsistency disrupts both research reproducibility and manufacturing throughput, with projects grinding to a halt to recalibrate formulas with every new drum. Our plant’s rigorous adherence to multistep batch validation virtually erases these headaches, something our long-term partners can attest to from their own records.
Some producers rely heavily on stockpiled intermediates, risking unintended side-reactions as feedstocks age. Our philosophy opts for minimal stockpiling and fresh synthesis per consignment, even if it adds a logistical planning layer. This means the time between production and delivery stays short, translating to longer shelf life and reduced risk of hydrolysis or oxidative change on the customer end. The feedback we receive—from multinational supply managers and independent labs alike—keeps confirming that these differences matter, especially for operations under regulatory or contractual constraints on finished good quality.
Handling and packaging protocols further set us apart. While bulk providers sometimes skip full-line closed transfer or nitrogen blanketing to save costs, we saw early that trouble-free handling saves more in the long term. Fewer spills, less product lost to degradation, and a better working environment in our own facilities all build into the value the end-user experiences. We encourage plant visits and third-party inspections, and hosted several in recent years specifically so clients could verify these standards for themselves.
One of the most rewarding aspects of direct manufacturing is the ongoing feedback loop with users of our products. Whether from academic research labs, multinational manufacturers, or independent consultants, the technical queries and suggestions we receive directly influence improvements and guide our next steps for both quality and logistics. Rather than treat these conversations as checkboxes to tick, we involve plant chemists and process engineers in customer calls, equipping them with the authority and knowledge to suggest modifications or troubleshoot problems far beyond what template-driven support could handle.
We remember a particular case where a customer’s batch reactor system kept fouling during a humid summer. Instead of shifting the blame, our engineers scheduled on-site diagnostics and recommended a switch to a desiccated packaging variant tailored to their storage conditions. After implementation, their fouling issues dropped by over 80%. Successes like this keep reinforcing our belief in hands-on, collaborative solutions. Manufacturing is about solving actual problems, not just moving material from point A to point B.
As end uses for O,O-Diethyl-O-(4-Nitrophenyl) Phosphorothioate keep evolving, so do the expectations of those purchasing and applying it. Advances in crop protection chemistry, for instance, have resulted in changing requirements for material purity and performance. By keeping our process lines nimble and allocating time for in-house and collaborative R&D, we stay in position to respond rapidly when requests shift. Not every adjustment promises immediate payoff, but a strong track record of successful client-driven product improvements gives our team confidence that targeted innovation beats a one-size-fits-all approach every time.
Some larger chemical concerns maintain a wall between research and manufacturing, leading to delays turning lab discoveries into plant-scale reality. Our team runs smaller R&D lines alongside production, enabling pilot batches to get feedback within weeks, not months or quarters. This proximity accelerates technology transfer, which in turn benefits customers who run aggressive timelines or regularly need custom variants.
Sustainability in chemical manufacturing used to be about checking boxes for audit compliance. In our experience, it’s about much more—building a safe workplace, reducing waste, and respecting both the community and regulatory frameworks that let us operate. By investing steadily in waste minimization, emissions reduction, and worker training, we not only keep prices competitive but protect the long-term prospects for everyone involved. Plant upgrades in recent years include solvent recovery loops, improved vapor recovery, and digital tracking of environmental data to spot trends before they become problems.
We keep a running record of energy and water usage, using these benchmarks to justify changes in equipment and process that cut costs and emissions at the same time. The process benefits customers directly through fewer disruptions and indirectly by aligning with their own sustainability targets—an increasingly important criterion in B2B procurement. What we learn from each audit helps refine our next investment, keeping us moving forward in step with industry best practices and emerging local and international standards.
Over time, manufacturing O,O-Diethyl-O-(4-Nitrophenyl) Phosphorothioate has been about more than technical achievement. It’s a process defined by attention to detail, openness to customer critique, and mindful evolution in line with both regulatory and market demands. Every improvement we make reflects the genuine practical challenges and successes of our partners. Choosing a supplier with real manufacturing experience means gaining the confidence that each step, from raw material selection to packaging and shipping, reflects a shared commitment to safety, reliability, and long-term business health. Anyone using this product for research, production, or industrial processing reaps benefits rooted in these values—and as users raise the bar ever higher, we stand ready to do the same in our processes every day.