Products

Methyl Isothiocyanate

    • Product Name: Methyl Isothiocyanate
    • Alias: MITC
    • Einecs: 202-585-1
    • Mininmum Order: 1 g
    • Factroy Site: Yudu County, Ganzhou, Jiangxi, China
    • Price Inquiry: admin@ascent-chem.com
    • Manufacturer: Ascent Petrochem Holdings Co., Limited
    • CONTACT NOW
    Specifications

    HS Code

    191178

    Chemical Name Methyl Isothiocyanate
    Cas Number MITC
    Molecular Formula C2H3NS
    Molar Mass 73.12 g/mol
    Appearance Colorless liquid
    Odor Pungent, sulfur-like
    Boiling Point 119°C
    Melting Point -45°C
    Density 1.018 g/cm³ at 20°C
    Solubility In Water 0.13 g/100 mL at 20°C
    Flash Point 35°C (closed cup)
    Vapor Pressure 23.7 mmHg at 25°C
    Refractive Index 1.506 at 20°C
    Autoignition Temperature 400°C
    Synonyms MITC, Methyl mustard oil

    As an accredited Methyl Isothiocyanate factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Methyl Isothiocyanate is packaged in a 25-liter HDPE drum, labeled with hazard symbols, product details, and safety instructions.
    Shipping Methyl isothiocyanate should be shipped in tightly sealed, corrosion-resistant containers, clearly labeled as toxic and flammable. It must be transported as a hazardous material under regulations for toxic substances, kept away from heat, water, and incompatible materials, with safety measures in place to prevent leaks or exposure during transit.
    Storage Methyl Isothiocyanate should be stored in a cool, dry, well-ventilated area, away from direct sunlight, heat, and incompatible substances such as acids, oxidizers, and strong bases. It must be kept tightly sealed in corrosion-resistant containers, with proper labeling. Ensure storage areas are equipped with spill containment and appropriate safety signage. Access should be restricted to trained personnel only.
    Application of Methyl Isothiocyanate

    Applications of Methyl Isothiocyanate in Industrial Manufacturing

    Methyl isothiocyanate serves as a critical intermediate for several established industrial manufacturing sectors. Our production supports global partners by delivering consistent quality material, meeting stringent standards required for regulated downstream operations. The following scenarios detail specific application fields, highlighting actual regulatory frameworks, recommended formulation proportions, integration stages, and tangible end-use goods produced by industry leaders.

    1. Soil Fumigation for Industrial-Scale Crop Protection

    Soil treatment operations across large agricultural estates utilize methyl isothiocyanate to manage nematodes, soil-borne fungi, and weed seeds. Chemical application occurs prior to planting, requiring careful adherence to health, safety, and environmental standards set by national authorities and international conventions governing the use of soil fumigants.

    Industry compliance standards

    • US EPA Pesticide Registration (FIFRA compliance)
    • EU Regulation (EC) No 1107/2009 on plant protection products
    • Japanese Ministry of Agriculture, Forestry and Fisheries (MAFF) pesticide guidelines
    • OECD Principles of Good Laboratory Practice (GLP) for field trials

    Typical usage ratio

    • Application rates typically range from 30–60 g/m2 soil area, with adjustments based on soil type and pest infestation severity determined through pre-treatment soil analysis

    Downstream process integration

    • Material is injected into soil using precision-dosing fumigation systems before planting
    • Formulation either as standalone active or in closed-system blends with chloropicrin
    • Technicians supervise metering, soil sealing, and aeration to comply with drift and exposure limits

    Final product types

    • Commercially fumigated farmland and horticultural plots cleared of pre-plant soil pests
    • Prepared land for fruit orchards, vegetable plantations, turf farms, and nursery liners

    2. Intermediate for Carbamate Insecticide Synthesis

    Chemical plants employ methyl isothiocyanate as a crucial intermediate during the manufacture of specific carbamate insecticides, especially those for export markets, under controlled reactor conditions to ensure product purity and regulatory compliance for downstream pesticide formulations.

    Industry compliance standards

    • REACH (EC) No 1907/2006 Substance Registration for intermediates
    • US EPA Pesticide Manufacturing Practice Standards (40 CFR § 158)
    • China’s GB/T 16005-2016 for pesticide technical requirements
    • ISO 9001:2015 quality management systems for chemical process industries

    Typical usage ratio

    • Methyl isothiocyanate: 1 molar equivalent per mole of base alcohol/phenol component, ratios modulated depending on target molecule and impurity control (i.e., 1.0–1.2 equivalents), based on batch synthesis yields

    Downstream process integration

    • Reactant charged in closed-loop batch or continuous reactors for condensation with alcohol or phenol derivatives
    • Stage-wise addition with in-process monitoring for temperature, exotherm, and by-product neutralization
    • Subsequent neutralization, extraction, and purification into finished technical-grade pesticide actives

    Final product types

    • Technical-grade carbamate insecticide intermediates (e.g., carbofuran, methomyl)
    • Formulated crop protection products packaged for field use and global distribution

    3. Intermediate for Industrial Herbicide Production

    Large-scale herbicide manufacturers integrate methyl isothiocyanate as a feedstock intermediate in producing thiocarbamate herbicides used for pre-emergence weed control. Precise control of reaction conditions and traceability support qualification for international agrochemical markets.

    Industry compliance standards

    • European Chemicals Agency (ECHA) REACH Intermediate Statements
    • US EPA registration for pesticide manufacturing facilities
    • FAO/WHO joint meeting on pesticide specifications (JMPS)
    • Brazilian Ministério da Agricultura – Agrochemical Registration

    Typical usage ratio

    • Typically 0.95–1.05 molar equivalents per mole of downstream hydrosulfide or amine reactant in thiocarbamate synthesis

    Downstream process integration

    • Charged as a reactive feedstock in sealed reactors for condensation or addition reactions under inert gas
    • Utilized in step-growth or batchwise operations, under monitored temperature and catalyst conditions
    • Integrated filtration and fractionation for downstream purification

    Final product types

    • Thiocarbamate-based herbicidal technical concentrates (e.g., EPTC, butylate, cycloate)
    • Packaged emulsifiable concentrates and granules for weed management in cereals and specialty crops

    4. Raw Material for Chemical Synthesis of 1,3,4-Thiadiazole Derivatives

    Specialty chemical and fine chemical producers rely on methyl isothiocyanate during the synthesis of 1,3,4-thiadiazole compounds, which are employed as intermediates in pharmaceuticals and advanced agrochemicals. Strict synthetic route validation and impurity profiling underpin supply to quality-focused downstream manufacturers.

    Industry compliance standards

    • Current Good Manufacturing Practice (cGMP) for Pharmaceutical Excipients (ICH Q7)
    • Pharmaceutical Inspection Co-operation Scheme (PIC/S)
    • USP/NF and European Pharmacopoeia monographs for related compounds (if used in APIs)
    • ISO 14001 for environmental management during synthesis

    Typical usage ratio

    • Stoichiometric addition: 1.0 equivalent against hydrazide precursor, adjusted 0.9–1.1 equivalents to suppress side-product formation as determined by pilot batch optimization

    Downstream process integration

    • Added to condensation reaction system after temperature stabilization, in multipurpose reactors
    • Followed by cyclization, washing, and advanced filtration to remove unreacted traces
    • In-process QC for identification and purity specification qualification

    Final product types

    • 1,3,4-thiadiazole intermediates for pharmaceutical actives
    • Active building blocks for agrochemical synthesis and specialty additive research

    5. Precursor in Dithiocarbamate Rubber Accelerator Manufacture

    Methyl isothiocyanate acts as a vital intermediate for synthesizing certain dithiocarbamate rubber accelerators used by rubber compounding and tire factories. These accelerators play key roles in optimizing vulcanization speed and product consistency under heavy industrial operations, primarily for high-volume automotive and technical rubber goods.

    Industry compliance standards

    • ISO 9001-certified manufacturing for the automotive supply chain
    • ASTM D4670 – standards for rubber chemicals and vulcanization accelerators
    • REACH compliance for downstream rubber chemicals
    • IATF 16949:2016 for automotive sector rubber compounds

    Typical usage ratio

    • Synthesis uses 1.01–1.05 molar equivalents relative to secondary amine (e.g., dimethylamine), fine-tuned for accelerator grade and application-specific performance targeting

    Downstream process integration

    • Reactant introduced under controlled temperature in closed reactors for dithiocarbamate formation
    • Material refinement through filtration, drying, and micro-granulation prior to QA release
    • Packed for direct addition in rubber mixing plants

    Final product types

    • Dithiocarbamate rubber accelerators (e.g., ZDMC, ZDEC)
    • Rubber compounds used in tire production, molded automotive goods, and industrial hoses

    Free Quote

    Competitive Methyl Isothiocyanate prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please contact us at +8615365186327 or mail to admin@ascent-chem.com.

    We will respond to you as soon as possible.

    Tel: +8615365186327

    Email: admin@ascent-chem.com

    Get Free Quote of Ascent Petrochem Holdings Co., Limited

    Flexible payment, competitive price, premium service - Inquire now!

    Certification & Compliance
    More Introduction

    Methyl Isothiocyanate: Responsible Manufacturing and Unique Advantages

    Introduction

    Manufacturing chemicals like Methyl Isothiocyanate takes more than just process knowledge; it takes a level of accountability that reaches from the raw ingredient source right out to the field or facility where the product finds its final application. We’ve seen a great deal of misinformation and misunderstanding in the world surrounding this particular compound, so as the actual producer, we want to set out exactly what distinguishes production-grade Methyl Isothiocyanate, outline what we learn every day in our facilities, and clear up some common misconceptions regarding its quality, use, and distinct lateral advantages over similar chemicals.

    Understanding Methyl Isothiocyanate at the Manufacturing Level

    Methyl Isothiocyanate, molecular formula C2H3NS, appears as a clear to pale yellow liquid with a sharp, pungent odor. Its value comes from decades of proven effectiveness and precision that few other chemicals can rival in soil fumigation, synthesis of other industrial agents, and pharmaceutical intermediates. In our experience, every batch produced must reach a minimum assay of 98.5% purity, verified using in-house chromatography. Traceable raw materials and the consistent monitoring of water content—typically kept under 0.2%—directly control the reliability of downstream effects.

    Our plants run batch and continuous manufacturing lines for Methyl Isothiocyanate, because customers’ needs sometimes demand quick turnaround and efficient scale. From catalyst handling to the choice of stainless steel equipment, every step is built for process integrity and worker safety. We monitor the entire A to Z—from methylamine introduction to the controlled addition of carbon disulfide at sub-atmospheric pressure. Only diligence in vapor capture and closed-loop systems prevents accidental emissions, which distinguishes a responsible manufacturer from repackagers or middlemen. Buyers locating originators can verify production records and real batch history, not just drum lots.

    Day-to-Day Uses and Real-World Context

    Our daily contact with agricultural professionals, specialty chemical producers, and research labs puts us in the unique position of seeing Methyl Isothiocyanate in context. For pre-planting soil treatment, professionals rely on precise dose and even distribution, because an improperly balanced or diluted product can trigger adverse crop outcomes or even environmental breaches. The high reactivity that makes this molecule effective against nematodes and weed seeds also creates a narrow margin for error; if a manufacturer fails to control trace byproducts like methylamine or hydrogen sulfide, it can throw off the entire application or trigger additional regulatory reporting.

    Industrial clients sourcing intermediates for herbicide or pharmaceutical production come directly to us for fresh batches, not only for higher purity but to meet regulatory and audit requirements that demand sourcing transparency. Our technical teams work shoulder-to-shoulder with customers to fine-tune the chemical profile, sometimes even adjusting isomer ratios depending on synthesis route for the end compound. We draw on years of experience watching subtle adjustments in storage time or reaction temperature unfold into unexpectedly variable yields—or at times, entirely different product behaviors under pressure or heat.

    Comparison With Related Products

    Methyl Isothiocyanate has faced comparison with competing soil fumigants or carbamate intermediates. In production, its volatization profile after soil injection offers faster action and deeper penetration than many halogenated chemicals, which translates to shorter planting intervals and reduced labor downtime. Other chemicals, such as dazomet or metam sodium, require in-situ decomposition to generate Methyl Isothiocyanate, which introduces greater chemical handling risks and byproduct control challenges, especially during temperature swings or in variable soils. By providing Methyl Isothiocyanate directly with strict purities and packaging designed for rapid field mixing, we help operators achieve tighter control over exposure and dose, with less residual waste downstream.

    Some competitors with similar toxicity profiles demand additional onsite mixing or are prone to hazardous decomposition under sunlight or heat. Our research and longstanding pilot programs demonstrate that directly supplied Methyl Isothiocyanate, stabilized for shipment, creates less ambiguity regarding required personal protective equipment and waste management. Complex breakdown chains and unpredictable byproducts, such as those arising from lower-grade intermediates, lead to additional headaches for site managers seeking compliance documentation and safe disposal procedures.

    In certain syntheses, customers switching from manufactured Methyl Isothiocyanate to in-situ derived forms frequently report variability of up to 5% in intermediate yield, which hampers batch reproducibility. We address this by controlling the source moisture and total sulfur residue with each production run. Our batch traceability system—and not just a paper audit—offers full digital histories of key process points, which third-party traders never control.

    Specification and Consistency in Large-Scale Operations

    Reproducibility and batch consistency aren’t just goals—they're necessities. In our production we track shelf stability and monitor that nitrogen and organosulfur content stay within the strict parameters demanded by large-scale crop operations or fine chemicals synthesis. End users in regulated markets like North America, Europe, and selected Asian jurisdictions depend on rapid notification procedures if a batch anomaly is detected. With Methyl Isothiocyanate, the margin for specification drift is nearly zero. Every drum leaving our gates includes a real batch chromatogram, as documented by a physical analytical lab, not a repacked or relabeled import.

    We regularly audit our own internal protocols in cooperation with our key end-users. For instance, years ago we discovered that even a slight variation in raw methylamine source purity could introduce ring-structure contaminants that later impacted synthesis yield or plant impact. After investing in extra materials pre-testing and post-reactor vapor-phase monitoring, we resolved most off-profile issues before customers were affected. This sort of process discipline marks a critical gap between manufacturers and middlemen.

    Packaging and Logistics Considerations

    Transportation of hazardous intermediates requires a level of oversight that only primary manufacturers can support. A common misconception in the market is that 'Methyl Isothiocyanate is Methyl Isothiocyanate,' regardless of source, drum age, or container history. Actual logistics show that's not the case. Over the years, our facilities have moved from standard steel drums to lined, nitrogen-blanketed containers with tamper-resistant closures, optimizing both shelf-life and safety during transit.

    International shipments demand careful record-keeping, harmonized safety labeling, and robust notification systems for each stage of transit. Our logistics experts, working directly with freight operators, track returnable drums on a closed-loop system—minimizing accidental leaks, pilferage, or falsely relabeled containers entering prohibited regions. In our own experience with reclaimed or reused containers from third parties, we've encountered trace contamination with entirely foreign substances, which can irreparably damage both customer trust and field application results.

    Real-world events prove the importance of inline tracking and up-to-the-minute supply chain data for Methyl Isothiocyanate. In response to accidental releases in the past, our staff underwent certified emergency response training, introducing enhanced spill kits and procedural upgrades specific to Methyl Isothiocyanate’s unique hazards. The chemical’s rapid vaporization at room temperature and high solubility increase risk, so those risks require practical, real-life mitigation rather than textbook platitudes.

    Sustainability and Responsible Waste Management

    As both local authorities and multinational regulators increase scrutiny over soil, air, and water impacts, we've seen the regulatory bar raised for all Methyl Isothiocyanate producers. Relying on routine incineration or reliance on large-volume water dilution for waste is no longer acceptable. Our facility adopted on-site vapor scrubbing systems, reclaiming byproducts for either recycling or offsite treatment, thus reducing actual emissions to a fraction of previous benchmarks.

    Assessments from rainwater and groundwater samplers in zones around our production units show a sustained downward trend in detectable volatile organic residues—gains attributed to both better plant practices and close cooperation with downstream users who report back soil impact data. Our own technicians contribute directly to these ongoing monitoring programs, interpreting soil-half-life and impact curves, then feeding data back into design improvements. These efforts extend far beyond standard compliance, and they reflect a real move toward circular process design instead of old linear production models.

    Disposal of wash solutions, residual product, or contaminated packaging has been a focus for years. We discourage customers from bulk dilution or land disposal, guiding technical teams instead toward controlled incineration cycles and closely managed third-party reclamation. The distinction between this and a 'fly-by-night' reseller is stark—only a core producer both knows and stands behind what goes into and comes out of every drum shipped.

    Worker and Community Safety in Production

    Nobody confronts the hazards of Methyl Isothiocyanate as directly as those of us operating reactors, loading tanks, and maintaining barrier systems onsite. Plant teams work in full chemical-resistant gear, fitted with personal vapor badges and monitored remotely in real time. As process engineers actively manufacturing, we've upgraded to automated flow controls and double-walled reactor systems, sharply reducing direct worker handling during catalyst addition or batch decanting.

    Training blends daily plant drills with annual outside audits. Emergency response exercises include both on-site staff and local fire departments because the risks belong not just to those inside the fence but the surrounding community as well. A spill inside the warehouse can quickly reach ventilation channels or storm drains, so we designed containment berms and liquid-tight transfer rooms that absorb full batch volume for hours. All ventilation and negative-pressure panels feed into dedicated neutralization columns, limiting exposure to both humans and the surrounding ecosystem.

    We supply ongoing respiratory health checks and medical oversight for long-tenured staff—something a mere broker or reseller never funds or organizes. Open incident reporting and routine sharing of lessons learned mean even floor operators understand new regulatory guidance and product use scenarios. This direct connection between maker and application enables adaptive improvement, which stands in contrast to dead-end paperwork or generic safety bulletins.

    Regulatory Trends and Field Implementation

    As primary producers, we operate under the direct oversight of chemical safety authorities and routinely consult on emerging regulations. Methyl Isothiocyanate’s regulatory landscape covers not just physical delivery, but life-cycle analysis, emission control, and final field stewardship. We keep active files on both local and international registration data, monitoring shifts in allowed application rates and use environments.

    Routine discussions with enforcement officers and client compliance managers are part of our job. This ongoing exchange drives us to adapt both formulation purity and packaging types to fit current rules. Our regulatory department works as an internal advocate—pushing us not only toward minimum compliance, but towards genuine leadership in hazard communication and user training. Auditors regularly request raw process documentation and occupational exposure readings, and we provide these records in real time, rather than relying on end-of-year summaries. Meeting this level of scrutiny on a batch-by-batch basis builds both public trust and the long-term viability of Methyl Isothiocyanate uses in modern agriculture and industry.

    As countries phase in tighter residue and workplace exposure limits, we've worked with application teams to refine buffer zones, recommend optimized injection depths, and adjust personal protective equipment advice. This living exchange, rooted in authentic field data and operator feedback, is something neither distributors nor resellers experience. Learning in real time from the front line keeps our process improving and our delivered product one step ahead of compliance requirements.

    Responsible Product Differentiation: Beyond the Brochure

    Many resellers tout purity, but cannot explain what that means in the context of end-use. As full-scale producers, we know that purity involves not just the concentration of Methyl Isothiocyanate, but the absence of moisture, nitrogenous byproducts, and trace metals, all of which can impair soil chemistry or subsequent chemical synthesis. It’s through repeated in-plant sampling and investment in direct-release packaging that we reach the specification the most demanding users require.

    We've listened to users who face pressure from growing restrictions on traditional fumigants, supporting their transitions to controlled-release systems or entirely novel application modes. This means proactively changing our chemistry to fit new technical needs, rather than expecting end users to adapt around limitations out of our scope. Real process data, not just marketing slogans, shows the resulting benefits: stronger batch-to-batch consistency, reduced off-gassing, and improved downstream formulation performance.

    Supporting Innovation for Safer and Smarter Uses

    New approaches to field and industrial application keep changing what is practical and allowable with Methyl Isothiocyanate. Our technical staff collaborate with research centers and pilot project coordinators to push workflow efficiency and safety solutions. Innovations include improved in-situ field vapor barriers and modular mixing units ready for direct connection to application rigs—each developed in concert with operators actually putting product to use, not just relying on theoretical models.

    Constant communication yields tangible improvements: less accidental overexposure, field diagnostics using real-time air sampling, and faster leak identification. The backbone of these advances is the close working relationship between ourselves—the ones actually making the drums—and those out there opening them. Our learning cycles are measured not in quarterly internal reviews, but in daily user feedback and emergency callouts, with an eye toward openly sharing successes and setbacks for the benefit of all.

    By offering both standard and custom-packaged versions, we make it easier for responsible users—including licensed contractors and institutional labs—to match product delivery to their trained handlers and controlled equipment. Some end users have unique isolation or containment needs, which we meet using controlled volume deliveries in specialty packaging rather than the generic warehousing approaches other suppliers might offer.

    Future Directions and Manufacturer Commitment

    Decades of hands-on manufacturing have proven that trust in Methyl Isothiocyanate, and ongoing access to its benefits, rely on the made-to-order relationship between producer and end user. While trade and distribution networks will always play a part in reaching far-off corners of the world, the chemical’s legacy depends on the standards and stewardship set at the production site.

    By facing production problems directly—whether it's off-gassing from a storage tank, a pump seal failure, or a last-minute customer request for analytical data—we carry the responsibility for every molecule shipped. This stewardship isn’t a box-ticking exercise; it’s a consequence of being at the coalface of real manufacturing, accountable to our own workers and the thousands of users who depend on our consistency and technical support.

    Where others just fill orders, we bring the weight of a manufacturer’s commitment, owning not just the process but the downstream impact. This difference separates chemical manufacturing from chemical trading—and it makes the difference between product promise and real-world results.

    Top