| HS Code | 430527 |
| Chemical Name | Methyl 2-Hydroxypropionate |
| Synonyms | Methyl lactate |
| Molecular Formula | C4H8O3 |
| Molecular Weight | 104.10 g/mol |
| Cas Number | 547-64-8 |
| Appearance | Colorless to pale yellow liquid |
| Boiling Point | 144-145 °C |
| Melting Point | -25 °C |
| Density | 1.11 g/cm3 at 20 °C |
| Solubility In Water | Miscible |
| Flash Point | 61 °C (closed cup) |
| Refractive Index | 1.4190 at 20 °C |
| Odor | Mild, fruity odor |
As an accredited Methyl 2-Hydroxypropionate factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | Methyl 2-Hydroxypropionate is packaged in a 500 mL amber glass bottle with tamper-evident seal, labeled with hazard information. |
| Shipping | Methyl 2-Hydroxypropionate should be shipped in tightly sealed containers, protected from moisture, heat, and direct sunlight. Ensure the container is appropriately labeled and complies with relevant transport regulations. Handle with care to prevent leakage or spills, and store in a cool, well-ventilated area during transit to maintain product integrity. |
| Storage | Methyl 2-Hydroxypropionate should be stored in a cool, dry, and well-ventilated area, away from direct sunlight, heat sources, and incompatible substances such as strong oxidizers or acids. Keep the container tightly closed and properly labeled. Store at room temperature in a chemical-resistant container. Ensure storage areas are equipped with spill containment measures and follow all local regulations regarding hazardous chemicals. |
Methyl 2-Hydroxypropionate is a key intermediate and specialty solvent utilized in multiple high-value manufacturing sectors. As the original producer, we supply downstream clients who depend on precise quality and predictable performance in regulatory-compliant formulations. Below, we detail major industrial application segments, process methodologies, and relevant standards associated with this raw material.
Agrochemical manufacturers incorporate Methyl 2-Hydroxypropionate as a synthetic intermediate in the preparation of selective herbicide and fungicide actives, especially for esterification and alkylation steps required in proprietary APIs. This chemical acts as a core building block for pyridine and triazole-based agro products, owing to its reactivity and purity profile. Formulators adjust batch requirements based on target molecule loadings and process optimization requirements to maximize yield and minimize waste.
Industry compliance standards
Typical usage ratio
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In pharmaceutical synthesis, manufacturers employ this material as an advanced intermediate for chiral active pharmaceutical ingredients (APIs). Its hydroxyl and ester functionalities allow for high purity transformations under cGMP protocols. The molecule is especially crucial in small molecule synthesis via asymmetric hydrogenation, protecting group chemistry, and lactone ring-opening reactions. Precise in-process control and documented traceability ensure alignment with health authority standards.
Industry compliance standards
Typical usage ratio
Downstream process integration
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Electronic chemical producers utilize this compound as an ultra-pure solvent base and cleaning agent for microelectronics manufacturing. Its low toxicity and rapid evaporation profile make it effective in photoresist removal, wafer cleaning, and degreasing process steps. High purity, residue-free performance is required for production on lines certified to advanced IC and display technology standards. Quality assurance and batch traceability support consistently tight impurity tolerances.
Industry compliance standards
Typical usage ratio
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In industrial coatings, our customers use this raw material as a monomer and functional co-monomer during resin and polyurethane synthesis. The compound introduces hydrophilic properties and controls polymer chain architecture in specialty coatings—especially for waterborne or radiation-curable formulations. Manufacturing processes require precise metering to avoid gelation or phase separation, with all material entering the reactor under real-time viscosity and solids control.
Industry compliance standards
Typical usage ratio
Downstream process integration
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In our years perfecting Methyl 2-Hydroxypropionate, we’ve learned that even a single percentage shift in purity or water content can change the way entire runs perform in downstream applications. This compound, often recognized for its role as a solvent, intermediate, or building block, stands out in our production for how well it responds to rigorous process control. We produce it under controlled conditions to achieve consistent quality every batch, whether it’s destined for fine chemical synthesis or coatings. Chemists on our floor check each lot for clarity, color, and verified assay, not just to tick off boxes on a chart, but because small unplanned shifts lead to larger issues for the users down the line. Our most requested grade lands above 99% purity (by GC), with residual water held under 0.1%. Not every user demands this, but experience shows that chemistry often gets easier when you don’t spend time troubleshooting off-notes or product failures that trace back to upstream impurities.
Every kilogram of Methyl 2-Hydroxypropionate coming off our reactors has passed direct checks for composition, water, and color. The liquid appears colorless to pale yellow, a trace of hue reflecting either time in storage or the making process. Specific gravity sits in a repeatable range, lending predictive handling for customers who meter or blend directly from drum or IBC. Boiling range on fresh lots comes in tight; portions distilling high or low signal something’s out of tolerance.
One recurring question from clients: “Why do your certificates detail formic or acetic acid traces?” Decades in the plant floor taught us that knowing the byproducts and keeping them low—well below the 0.1% mark in our specs—prevents headaches for anyone using this reactively or in food-contact chemical synthesis. We track other trace organics, not only for compliance, but because stubborn contamination echoes in final products all the way to the lab bench.
Years of feedback on how Methyl 2-Hydroxypropionate gets used have shaped the way we approach its manufacturing. Many customers require it as a monomer or co-monomer for specialty polymers. You’ll find it upgrading crosslink density, softness, or flexibility in specific resins—settings where functional group balance counts for more than just theoretical numbers. Others in the cosmetics field depend on its role as a safe, easy-to-handle intermediate. Purity differences show up quickly in these areas, causing either smooth upgrading of product lines, or, if corners are cut, batches written off due to off-color or odor.
Our regular partners in the coatings world tell us that water balance in the raw Methyl 2-Hydroxypropionate affects not only reactivity, but also shelf stability of their blended intermediates. Multiple seasons of production confirm one fact: controlling water and volatile impurities sets the standard not only for handling, but for downstream process yield. This isn’t the sort of insight that comes out of a generic spec sheet—it’s the result of large and small producers running real-world applications and reporting back to us over years.
Methyl 2-Hydroxypropionate shares some functional overlap with other methyl esters or substituted hydroxy esters. We see customers weighing it against Methyl Lactate, Ethyl 2-Hydroxypropionate, or even Methyl Glycolate when setting up new processes or reformulation projects. Several factors consistently push them back to our offering. The methyl ester provides a sharper boiling point and easier recovery than the ethyl analog, which opens up more flexible options in recycling and distillation setups. Low water solubility also sets it apart from Methyl Lactate, depending on application needs. This difference shows when processes rely on slow hydrolysis, or where customers want to simplify separation from aqueous phases.
Working directly as the manufacturer, we can adjust process parameters—reaction time, purification technique, even raw input ratios—in ways that third-party blenders or repackers simply can’t. We analyze feedback from hands-on chemists and engineers: sometimes a customer reports issues with foaming or unexpected side-color after blending; our production team can trace this back to a small byproduct or processing step, tweak the manufacturing train, and supply updated lots. This immediate cycle of production and feedback can’t happen without full control over the reactor and distillation lines.
People often want to know if Methyl 2-Hydroxypropionate will blend directly into their standard solvents, or if it interacts differently under storage conditions. In practice, this chemical holds up well under ambient storage for months, especially when sealed under nitrogen. Exposure to air over time brings slow hydrolysis—all common with esters—but fresh product from our facility resists such breakdown thanks to low water content and neutralization checks. For those handling in bulk, we recommend stainless steel or glass-lined receiving tanks, since raw carbon steel accelerates color pickup and flavor taints in sensitive applications.
During colder months, viscosity may climb slightly, but the liquid remains pumpable down to near-freezing without sludging. Any observed crystallization points to possible adulteration, as our standard grades remain well above their freezing point in the cold-chain or non-heated storage.
On the topic of downstream reactions, we regularly get inquiries about compatibility with acid or base catalysts. Our long-term users in polyester or acrylic resin industries find Methyl 2-Hydroxypropionate manageable under both acid and base-catalyzed conditions. Trace acid or basic impurities can trigger runaway reactions or poor conversion, so each outgoing lot gets titration testing to confirm low residuals. Those quality steps grew out of troubleshooting support—sometimes a single missed QA check in an intermediate can cost a customer a full reactor cycle or several drums of higher-value material.
We stay current on how regulatory requirements for ester solvents and intermediates change globally. Some regions push for REACH-type registration, while North American standards revolve around FDA, TSCA, or state-level oversight. Instead of retrofitting compliance onto products, our production cycles build in documentation from synthesis through shipment. Logs capture not just what went into the reactors, but timing, temperatures, and purification procedure. If a customer has an audit or must verify back to original lot data, we can supply more than a generic certificate.
Safe handling factors into each production run. The flammability and odor threshold of Methyl 2-Hydroxypropionate rate as comparable to other short-chain esters but require attention for those loading drums or tanks by hand. We fit our filling lines with closed systems and vapor return to minimize worker exposure. Our facility recovers and scrubs vent emissions, not only for compliance, but due to long-term experience with lingering odor complaints downstream. Early years taught us that unfiltered storage and transfer prompt more end-user complaints than almost any variable we can control in-house.
With environmental attention mounting, solvent and intermediate producers face growing questions about biodegradability, atmospheric release, and safe disposal. Methyl 2-Hydroxypropionate offers advantages on the biodegradation front; its structure allows for ready breakdown under aerobic conditions, confirmed by independent testing. Disposal coordination with local waste handlers remains necessary, especially for spent or off-spec lots cross-contaminated by other process materials, but risk of persistence in soil or water rates lower than many other specialty esters.
We’ve faced plenty of process surprises. One production year saw seasonal ambient temperature shifts causing higher back-pressure in our distillation columns. Rather than recipe adjustments on paper, our operators modified cycle rates in real time, tracking output with both electronic monitoring and regular bench testing for distillate quality. The outcome was a more repeatable product, and a new set of standards for seasonal adjustments, now followed company-wide.
Another occasion, a customer flagged foaming and haze on polymerization trials that correlated with a slight but measurable increase in our product’s acid value. Lab checks traced it back to a valve leak letting in ambient moisture, combined with unusually high local humidity. By integrating advanced inline drying and adding a real-time water-check to the outgoing flow, subsequent batches resolved the issue, and allowed for transparent correction reporting to the affected customer. This story illustrates how the learning loop between in-plant experience and user feedback provides genuine quality advances; it’s not simply ticking boxes on a QA checklist.
Long-term customers often ask about scale-up and whether batch-to-batch differences influence large-scale productions. Chemical reality makes it almost impossible to hit single-digit ppm tolerances for every specification, but we learned to track minute shifts in GC snapshot profiles, rather than only overall purity. Several resin or coating partners use our chromatograms as a fingerprint to predict how their own lines will respond—a practice that grows from years of communication, not just standard paperwork exchanges.
Formulators with unique solvent blends or performance polymers come to us because their end products demand repeatable attributes—no sudden color jumps, no unexpected gel times, no lingering odor trails months after mixing. Methyl 2-Hydroxypropionate provides a methyl ester backbone that introduces flexibility and processing freedom in blend formulations. It compares well against alternatives by offering a favorable evaporative profile and a more predictable reactivity in catalyzed reactions. Customers blending acrylics, alkyds, or polyurethanes see that drop-in differences affect not just factory protocols, but also the final user’s experience—whether that’s in a smoother finish for coatings, a softer touch in films, or improved solubility in personal care bases.
Long trial pipelines do not always leave room for troubleshooting variable-quality raw materials. We provide stability data, sample lots, and technical backup rooted in direct experience rather than only supplier literature. We see repeated, surprise-free mixing from clients who build on our tight control of byproduct profiles and batch-to-batch consistency.
Our job involves more than just supplying a drum. Development teams often request pilot volumes or special fractions for new application research. Having our own manufacturing infrastructure allows us to answer lab-scale requests with tailored samples that actually reflect commercial process conditions. Some partners need higher water grades for niche reactions. Others want an extra-neutralized product to avoid acid-catalyzed behavior in secondary reactions. Because we oversee synthesis from raw input to final fill, adjustments become possible at the drum rather than just the batch.
Technical support starts with open conversation. We regularly look at end-user data, visit customer plants where possible, and return with new insights to tune our approach. When formulators call with an unexpected performance issue, we have first-hand knowledge of what left our gates, which enables troubleshooting that goes beyond guesswork. It’s this relationship—rooted in recurring real-world scenarios—that grows trust over vendor-buyer paperwork or third-party arrangements.
Consistent, transparent operation forms the backbone of our long-term relationships. Customers with tight timelines and critical manufacturing windows select us because they trust in a chain free from unexplained supply breaks or “mystery lot” substitutions. As manufacturers, we take direct responsibility for the quality and traceability of every shipment. This means offering open data on batch performance, providing real-life use cases, and making practical recommendations around storage, compatibility, and handling.
Hesitation often arises with new suppliers; we respond with evidence, not sales pitches. Users facing new regulatory environments or quality audits can call on us for direct process history, COAs linked to batch data, and evidence of both long-term product stability and compliance with evolving guidelines. We see, across the industries we serve, a marked difference in operation quality and peace of mind for those who know exactly what’s coming off the line.
Methyl 2-Hydroxypropionate might sound like just another methyl ester to someone reading spec sheets, but hands-on experience reveals the difference that tight operational oversight and feedback-driven manufacturing bring to the table. Each iteration of our process reflects not only regulatory realities and technical hurdles, but also years of listening to what real-world chemists, engineers, and product developers need. Pure, consistent material makes a difference in scale-up, process yields, and end-user satisfaction. We treat every shipment as more than a box to be ticked—it’s a reflection of accumulated knowledge, open dialogue, and commitment to enabling better products for every application downstream.