Products

Iodine Trichloride

    • Product Name: Iodine Trichloride
    • Alias: Iodine(III) chloride
    • Einecs: 215-608-1
    • Mininmum Order: 1 g
    • Factroy Site: Yudu County, Ganzhou, Jiangxi, China
    • Price Inquiry: admin@ascent-chem.com
    • Manufacturer: Ascent Petrochem Holdings Co., Limited
    • CONTACT NOW
    Specifications

    HS Code

    927242

    Chemical Name Iodine Trichloride
    Chemical Formula ICl3
    Molar Mass 233.26 g/mol
    Appearance Yellow to brown crystalline solid
    Melting Point 63°C (145°F)
    Boiling Point 101°C (213.8°F)
    Density 3.10 g/cm³
    Solubility In Water Reacts, forming HCl and HIO3
    Odor Pungent, chlorine-like
    Cas Number 865-44-1
    Stability Unstable in moist air
    Hazard Class Oxidizing agent
    Main Use Analytical reagent and organic synthesis

    As an accredited Iodine Trichloride factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Iodine trichloride is packaged in a 100g amber glass bottle with a tightly sealed cap, labeled with hazard warnings.
    Shipping Iodine trichloride should be shipped in tightly sealed containers, separated from combustible materials and moisture. It is classified as a hazardous material (oxidizer, UN 3085) and typically transported under cool, dry conditions. Proper labeling, documentation, and regulatory compliance are required to ensure safe handling and transportation of this corrosive and reactive chemical.
    Storage Iodine trichloride should be stored in a tightly sealed, corrosion-resistant container, in a cool, dry, well-ventilated area, away from moisture, heat, and sources of ignition. It must be segregated from organic materials, reducing agents, and combustibles to prevent hazardous reactions. Always store it away from incompatible substances and ensure appropriate chemical labeling and safety precautions are maintained.
    Application of Iodine Trichloride

    Applications of Iodine Trichloride in Industrial Manufacturing

    Iodine Trichloride serves as a specialized halogenating agent and catalyst across select industrial verticals. Our manufacturing expertise ensures purity and consistency to meet stringent end-user processing requirements. Explore verified downstream sectors and technical integration details below.

    1. Pharmaceutical Active Ingredient Synthesis

    Pharmaceutical manufacturers employ Iodine Trichloride as a controlled oxidizing agent in iodination and dehydrogenation steps of APIs and intermediates. It plays a role in the targeted halogenation of aromatic compounds, especially in the synthesis routes for various iodinated small molecules, imaging agents, and hormone derivatives. Tight process controls and in-process analytical validation remain essential for impurity management and product batch traceability, with batch documentation enforced according to regulatory norms.

    Industry compliance standards

    • Current Good Manufacturing Practice (cGMP) as per 21 CFR Parts 210/211
    • United States Pharmacopeia (USP) standards for chemical reagents
    • European Pharmacopoeia (Ph. Eur.) guidelines
    • ICH Q7 for Active Pharmaceutical Ingredients

    Typical usage ratio

    • Employed at 1.2–2.5 molar equivalents relative to substrate
    • Adjusted depending on substrate electron density and stage yield optimization
    • Generally less than 5% by batch mass input for final step conversions
    • Process engineers establish dosage according to validated process design

    Downstream process integration

    • Dosed in jacketed glass-lined vessels under nitrogen protection
    • Reacted in pre-cooled solutions to control exothermic response
    • Residual iodine species removed by aqueous workup or sodium thiosulfate quench
    • Applied analytical release including residual halogen impurity testing

    Final product types

    • Iodinated X-ray and CT contrast media (e.g., Iohexol, Iopamidol)
    • Iodinated antiseptic intermediates (e.g., Povidone-iodine precursors)
    • Substituted thyroid hormone intermediates (e.g., Levothyroxine IPs)
    • Specialty APIs where aromatic iodination is critical

    2. Organic Dye and Pigment Manufacturing

    Producers of industrial dyes rely on Iodine Trichloride for controlled electrophilic aromatic iodination, especially when synthesizing triarylmethane and azo dye families. The reagent offers consistent reactivity for positional selectivity during halogenation, a key requirement for achieving desired chromatic properties. Customers demand thorough documentation of iodine impurity clearance and color value repeatability in every batch.

    Industry compliance standards

    • OEKO-TEX Standard 100 for textiles (where applicable)
    • REACH (EC 1907/2006) for imported/distributed colorants within Europe
    • ASTM D5433 guidelines for color additives
    • ISO 9001 Quality Management System certification for production chain

    Typical usage ratio

    • 0.05–0.15 parts per part of dye batch depending on substitution pattern
    • Process-specific; often 2–10% by weight in iodination stages
    • Optimized via HPLC shade and purity endpoint monitoring
    • Reduced in subsequent large-scale purification steps

    Downstream process integration

    • Fed into halogenation reactors prior to azo coupling or condensation steps
    • Reaction temperature controlled to 0–15°C to prevent byproduct formation
    • Unreacted iodine efficiently removed by extraction or crystallization
    • End-use approval relies on batch colorimetric testing and halogen residue validation

    Final product types

    • Triarylmethane dyes (e.g., methyl violet, crystal violet derivatives)
    • Azo pigment intermediates
    • Textile printing agents containing specialty iodine-substituted chromophores
    • Colorants for coatings and plastics

    3. Specialty Disinfectant and Biocide Formulations

    Iodine Trichloride acts as a core active agent for compounding high-strength iodine-based disinfectants and surface sterilizers. Its high oxidative potential supports rapid biocidal action against a broad range of pathogens in medical and veterinary environments. Manufacturers maintain strict storage and handling protocols to manage reactivity and control product outgassing, with robust end-use stability data required for registration dossiers.

    Industry compliance standards

    • U.S. EPA FIFRA 40 CFR Part 158 for antimicrobial pesticides
    • European BPR (Regulation EU 528/2012) for biocidal products
    • EN 1276 for chemical disinfectants (bactericidal activity)
    • ISO 13485 for medical device disinfectant production where relevant

    Typical usage ratio

    • 0.2–0.6% w/w of formulated product for direct-surface disinfectants
    • Higher ratio (up to 2% w/w) in concentrated industrial solutions
    • Adjusted for application contact time and surface compatibility
    • Final dose validated in suspension and carrier test protocols

    Downstream process integration

    • Dosed into blending tanks under negative pressure with continual agitation
    • Buffered with stabilizing agents to reduce volatility and corrosion risk
    • In-line monitoring for free iodine availability and pH adjustment
    • Packaged in corrosion-resistant containers with compliance labeling

    Final product types

    • Hospital-grade hard surface disinfectants
    • Veterinary biocidal sprays and foot bath concentrates
    • Industrial and institutional cleaning agents for sensitive equipment
    • Emergency decontamination fluids

    4. Analytical Laboratory Reagents and Iodometric Titration

    Analytical reagent formulators utilize Iodine Trichloride as a primary oxidant for iodometric volumetric analysis in pharmaceutical, food, and environmental QC labs. Its application in the preparation of standardized titrants and test solutions demands certified purity, precise assay stability, and batch-to-batch consistency under ISO/GLP requirements, serving a foundational role in the quantification of reducing substances and halide ions.

    Industry compliance standards

    • ISO 17025 accreditation for laboratory quality systems
    • United States Pharmacopeia Reagent Standards
    • GLP (Good Laboratory Practice) OECD Principles
    • ACS Reagent Grade specifications and acceptance criteria

    Typical usage ratio

    • Prepared as 0.01–0.1 N titrant solutions, exact concentration by method protocol
    • Batch variations not permitted in certified reagent packs
    • All volumetric solutions labeled with full traceability
    • Stock solution stability validated for required shelf life by ISO

    Downstream process integration

    • Diluted in standardized flaskware under laminar flow to prevent contamination
    • Filtered and sealed against UV to maintain assay integrity
    • Transferred to volumetric burettes or auto-titrators for analytical QC
    • Excess and blank run-off neutralized according to hazardous waste protocol

    Final product types

    • Certified volumetric titration reagents
    • Analytical kits for residual chlorine/oxidant testing
    • Calibrated lab standards for halide analysis
    • Official compendial test solutions for chemical QC

    Free Quote

    Competitive Iodine Trichloride prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please contact us at +8615365186327 or mail to admin@ascent-chem.com.

    We will respond to you as soon as possible.

    Tel: +8615365186327

    Email: admin@ascent-chem.com

    Get Free Quote of Ascent Petrochem Holdings Co., Limited

    Flexible payment, competitive price, premium service - Inquire now!

    Certification & Compliance
    More Introduction

    Iodine Trichloride: Practical Insights from the Manufacturer

    Understanding Iodine Trichloride from a Chemist’s Bench

    In the chemical works, people rely on clear results and practical consistency. Iodine trichloride (ICl3), recognized for its yellow to brown crystalline form, delivers dependable performance every time it enters the reaction vessel. Our production team handles this material daily, understanding its nature from decades of experience. Iodine trichloride is never just a bottle on the shelf; it plays an active role in real chemical processes, especially where oxidizing power and halogen exchange matter. Every batch we prepare involves careful weighing, secure containment, and clear documentation to meet strict specification targets every time. Technical users expect more than just a label, so we work to supply product that answers the needs of both laboratory and large-scale plant settings.

    How We Craft Iodine Trichloride in Our Plant

    Batch production of ICl3 means direct reaction between elemental iodine and chlorine gas. We control the temperature and pressure in real time with in-line sensors. This hands-on approach allows us to achieve the targeted crystalline structure, with purity routinely above 99%. Moisture content and free chlorine must be minimal, so we dry and package immediately under a dry nitrogen blanket. Glass-lined steel reactors prevent side-product formation and keep the material from corroding the equipment. Every final container gets checked for caking, color, and reactivity. By controlling every step from sourcing iodine to final packaging, we deliver product that users trust in both research and manufacturing scenarios.

    Core Technical Data and Why They Matter

    Our ICl3 comes in crystalline form with a molecular weight of 233.26 g/mol. Workers in our plant handle it at room temperature, handing off to packaging teams in climate-controlled lines that keep humidity well under 2%. Customers in the pharmaceutical and electronic sectors often request lots with trace-level heavy metal data, so our QC department provides a certificate for every batch. For catalytic halogenation, high-purity is pivotal. Laboratory teams in fine chemical synthesis tell us visible purity saves time and cost, enabling fast process validation and reducing the need for re-work. These details drive why we keep quality control strict; people downstream depend on reliable assay, clear color, and free-flowing texture to avoid surprises in both analytical and full-scale reactor applications.

    Common Applications and How Industry Uses ICl3

    Iodine trichloride stands out as a potent chlorinating agent. It's a cornerstone for halogen exchange, aromatic iodination, and selective oxidation in the synthesis of dyes, pharmaceuticals, and advanced organic compounds. On the shop floor or in the fume hood, chemists depend on its clear-cut performance to save time: stable enough to handle, but strong enough to shift halogen atoms without adding tedious purification steps. As an analytical reagent, it measures the presence of certain pharmaceuticals and fats by converting unsaturates and reacting with double bonds. Industrial-scale users value its consistent granularity, as clumping would block automated feeding systems. Research teams highlight its use as a mild oxidant in specialty synthesis, where alternatives like pure chlorine or bromine either overreact or demand harsher conditions.

    We've also noted rising demand in the electrolyte sector. Iodine trichloride features as a component in select high-energy storage and battery research initiatives, especially where designers experiment beyond lithium-based systems. Reliable supply makes process scalability possible from gram-scale trials all the way to pilot-plant demonstration. Customers report that switching from less stable chlorinating agents to ICl3 reduces maintenance and product loss, especially in batch reactors lined with specialty materials. The absence of excess by-products and better yield management can cut the cost of downstream cleanup.

    Handling, Storage, and Our Own Lessons Learned

    No matter how well you know your chemistry, the right precautions keep operations smooth. Our storage warehouse sits away from the main production hall, ventilated, and kept below 20 degrees Celsius. Iodine trichloride fumes in moist air, so we store it only in tightly sealed glass or Teflon-lined containers. Even small leaks corrode metal and discolor the workspace, so we learned from experience to check every seal twice and keep spare gaskets on hand. Operators suit up fully when transferring material: PAPR respirators, chemical splash goggles, and gloves rated for strong oxidizers. Spillage drills are routine, since once in contact with organic matter, the reaction can be vigorous and releases iodine vapors quickly.

    Feed chutes and valves demand regular inspection, because even well-manufactured ICl3 crystals can leave deposits that build up over time. Cleaning teams use only approved alkaline washes, as strong acids only speed up decomposition. Our safety officer regularly inspects all stored lots for signs of caking or color change; early intervention prevents any surprises when product reaches your laboratory. Many customers ask about shelf life—kept properly dry and sealed, our product can hold spec for over 12 months, sometimes longer. Snowy yellow color and free-flowing movement in the drum spell quality every day.

    Comparing Iodine Trichloride to Related Compounds

    Some customers look at iodine monochloride (ICl) as an alternative, but we see important practical distinctions. Iodine monochloride usually arrives as reddish-brown liquid, less stable on the bench and sometimes harder to dispense in measured quantities. Chlorine gas remains an industry staple for chlorinations, but its handling risk and reaction profile make it harder for specialty chemistry. In many aromatic substitution or oxidation reactions, ICl3 works at lower temperatures and grants more selective reactivity. Elemental iodine alone can’t provide the same oxidative drive, often requiring harsher conditions that limit process flexibility.

    For those comparing with brominating agents, such as bromine or N-bromosuccinimide, switching to ICl3 often delivers more controlled outcomes. Typical bromination steps risk over-reacting with sensitive substrates, while iodine trichloride enables a more nuanced hand. Direct chlorinating agents like thionyl chloride or phosphorus pentachloride, though powerful, demand very close monitoring and can generate large volumes of acidic by-products and corrosive gases. By contrast, ICl3 reacts with fewer unwanted surprises in well-dried systems. Over decades of production, we've watched project teams achieve higher yields on organoiodine compounds and better control on heterocycle formation with ICl3.

    Quality You Can Measure, Not Just Read About

    It’s common to see requests for “pharmaceutical grade,” “synthetic grade,” or “reagent grade.” We base each classification on direct feedback from end users and keep our lines flexible to deliver tight batch control and thorough documentation. Experienced chemists want more than technical bullet points; they look for exacting batch traceability, transparent audit trails, and ready access to analysis data. Our in-house lab calibrates every spectrophotometer weekly, cross-checking with international standards and blind controls shipped directly from trusted institutions. No one wants recalls or batch failures; our process minimizes these risks by tying every line operator’s logbook to digital tracking systems accessible both to our QC manager and—when needed—to your review team.

    We track shipping container conditions with time-stamped photos and humidity tags, tools developed out of early lessons in missed deliveries. Batch sampling always happens after filling—never before—to avoid bias. Many teams benefit from our open-door policy: visitors can audit our plant, inspect production records, and test random samples on the spot. We stand behind the product, knowing that direct observation and consistent reporting cut through any marketing claims.

    Solving Typical Issues in Scale-Up and Downstream Processing

    Research and scale-up pose different challenges. Chemists in research labs, working with a few grams, might notice rapid discoloration or sublimation when the product sits exposed. Production engineers running 200-liter lots watch for crystal bridging or handling jams in screw feeders. Both report that even slight moisture exposure diminishes yield and complicates filtration. From our end, we train staff to act on early warning: airlocks, dry-room transfer zones, and double-bag packaging all emerged from listening to customer pain points.

    We recommend users set up local containment wherever possible and finish transfers inside fume hoods or gloveboxes. For automated systems, lining feed bins with PTFE or using peristaltic pumps can reduce friction losses and material bridging. Where dust forms from handling, simple HEPA extraction keeps personnel safer and avoids product cross-contamination. Our customer helpline logs many questions about filter clogging and pump compatibility; we now share best practices directly based on field reports rather than relying on generic manuals. By working with end users on custom-sizing and pre-measured packs, we take pressure off production engineers left troubleshooting late at night.

    Supporting Responsible Sourcing and Environmental Safety

    Strong oxidizers demand more than clean chemistry—they need responsible handling across the board. Modern facility permits require proof of hazardous material management. We built our waste neutralization plant to handle both spent ICl3 and any absorbents exposed during packaging. Sodium thiosulfate and sodium hydroxide baths quench any remaining oxidizer, preventing improper release to local sewer systems. Emergency preparedness teams run quarterly drills, which means every shift keeps spill kits, chemical neutralizer bins, and personal protective equipment within arm’s reach.

    We monitor our local emissions and runoff as a matter of routine, not just compliance. Teams log pH, total halides, and oxidation potential morning and evening. We know that any incident or slip can draw scrutiny from environmental auditors; open reporting helps us build trust with chemical buyers, plant neighbors, and regulators alike. For outbound shipments, material leaves only in UN-approved containers, sealed and labeled for every transit point, never bulk-loaded or transshipped through uncontrolled carriers.

    Collaborating with customers on green chemistry approaches, we help research teams substitute less sustainable reactants with ICl3 in high-atom efficiency reactions. People care how starting materials affect the environment, so we work on building supply chains with lower carbon footprints and fewer hazardous process offgasses wherever possible.

    What Real Lab Tests Tell Us about Batch Reliability

    Application chemists sometimes express concern about batch-to-batch color variation—yellow hints at ultra high purity, browning suggests trace over-chlorination. Before packing any product, our technical team tests for both free iodine and combined chlorine content by titration and HPLC. In joint development projects, we've seen teams reduce analytical error by calibrating to our in-house control standards. When reaction operators hit unexpected results, we invite them to ship back samples for assessment and rapid feedback. Open technical support allows troubleshooting with engineers who manufacture the product, not salespeople reading from brochures. That’s a difference chemical buyers recognize once they move past sample-phase evaluations.

    Upstream supply disruptions sometimes affect raw iodine supplies, but by maintaining close ties with primary mines and strategic reserves, we buffer downstream volatility. Competing products sourced from anonymous channels risk inconsistent particle size, packing density, and moisture levels—we’ve documented these issues, especially in overseas deliveries. Direct manufacturer oversight means that users can expect the same processability with every pail. Our familiarity with plant-scale kinetics and end-process requirements lets us fine-tune every production run to meet new market trends and specialty project specs.

    Where Iodine Trichloride is Headed: Future Roles

    In specialty chemicals, innovation shifts with every grant, patent, or materials discovery. Researchers are exploring halide shuttling for organic semiconductors, with ICl3 as a controlled source. Battery developers continue to trial iodide-rich systems for safer and higher-density storage. Diagnostic test kit manufacturers want faster, less hazardous oxidants; ICl3 remains an attractive candidate. In our view, these trends show staying power. Our production team keeps in close touch with research consortia and industrial working groups, staying ready to adapt quality specs, packaging types, and drop-shipping logistics to support field tests and demos.

    From what we see, the future of ICl3 depends less on yesterday’s standardized role as a bench reagent and more on rapid adaptation to new technical requirements from both small startups and established multinational partners. We keep our process robust but nimble, scaling from kilo-lots for R&D to tonne-lots for full-scale rollout in new industrial arenas.

    Direct Connection: Why Work with the Actual Manufacturer

    Hands-on experience signals real value. Working face-to-face with the source beats any brochure or catalog claim. By manufacturing, testing, packaging, and shipping ICl3 in our own facilities, we maintain control at every link. End users benefit, not just through traceable quality, but from a technical support desk that listens to plant-floor challenges and helps solve real problems. Our doors stay open to audits, our technical sheets grow with customer feedback, and our promise remains the same: deliver ICl3 that works, every time, with no surprises or excuses.

    Top