Furfurylamine

    • Product Name: Furfurylamine
    • Alias: aminomethylfuran
    • Einecs: 208-945-1
    • Mininmum Order: 1 g
    • Factroy Site: Yudu County, Ganzhou, Jiangxi, China
    • Price Inquiry: admin@ascent-chem.com
    • Manufacturer: Ascent Petrochem Holdings Co., Limited
    • CONTACT NOW
    Specifications

    HS Code

    115084

    Cas Number 100-58-3
    Molecular Formula C5H7N
    Molar Mass 81.12 g/mol
    Appearance Colorless to yellowish liquid
    Density 1.048 g/cm³
    Melting Point -60°C
    Boiling Point 145-146°C
    Solubility In Water Miscible
    Refractive Index 1.556
    Flash Point 42°C (closed cup)
    Odor Amine-like
    Vapor Pressure 2.5 mmHg at 25°C

    As an accredited Furfurylamine factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Furfurylamine is packaged in a 500 mL amber glass bottle with a screw cap, labeled with hazard warnings and product information.
    Shipping Furfurylamine should be shipped in tightly sealed containers, protected from light, heat, and moisture. It is classified as a hazardous chemical and must be transported according to relevant regulations, such as DOT and IATA guidelines, typically as a flammable liquid. Proper labeling, documentation, and safety measures are required during shipping.
    Storage Furfurylamine should be stored in a tightly sealed container, in a cool, dry, and well-ventilated area away from sources of ignition, heat, and direct sunlight. It should be kept away from oxidizing agents and acids, as it is combustible and may react dangerously. Store the chemical under an inert atmosphere if possible, and ensure proper labeling to avoid accidental misuse.
    Application of Furfurylamine

    Applications of Furfurylamine in Industrial Manufacturing

    Furfurylamine plays a specialized role in several industrial manufacturing sectors as a reactive intermediate and functional chemical. Here, we detail main downstream applications across core industries, with focus on compliance, process specifics, and finished products.

    1. Synthesis of Pharmaceutical Intermediates

    Pharmaceutical manufacturers use furfurylamine as an essential building block in multi-step synthesis routes for specialty APIs. Its reactive amine group enables efficient formation of bioactive moieties, particularly in the preparation of antihypertensive and antiviral drug intermediates. Strict adherence to validated process parameters ensures consistent quality and regulatory acceptance of the resulting intermediates.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice (GMP) for Active Pharmaceutical Ingredients
    • European Pharmacopoeia (EP), United States Pharmacopeia (USP) monograph requirements for intermediates
    • 21 CFR Part 211 – FDA GMP standards

    Typical usage ratio

    • Typically 0.6 to 2.5 molar equivalents per key reaction step, tuned to desired yield and purity in each synthesis pathway.

    Downstream process integration

    • Direct addition during intermediate amination, Friedel-Crafts alkylation, or reductive amination steps within API or pre-API synthesis.

    Final product types

    • High-value pharmaceutical intermediates (e.g., furfuryl derivatives incorporated into cardiovascular or antiviral drugs)
    • Active pharmaceutical ingredients (APIs) following further conversion

    2. Manufacture of Corrosion Inhibitors for Industrial Systems

    Chemical formulators integrate furfurylamine in the synthesis of organic corrosion inhibitors for closed-loop water treatment and petrochemical systems. The compound reacts with aldehydes or epoxides, forming cationic or non-ionic additives with affinity for metal surfaces, reducing corrosion rates in boilers, heat exchangers, and pipeline infrastructure.

    Industry compliance standards

    • ASTM D1384 – Corrosion Test for Engine Coolants
    • ANSI/AWWA B100 for chemical additives in water treatment
    • REACH registration for environmental and worker safety in Europe

    Typical usage ratio

    • Final inhibitor formulations usually contain 3–15% by weight of furfurylamine-derived active substance, depending on water chemistry and corrosion load.

    Downstream process integration

    • Condensation or Mannich-type reaction steps with formaldehyde or other aldehydes, then blending into multi-component inhibitor packages.

    Final product types

    • Industrial water treatment corrosion inhibitors
    • Pipeline protection fluids
    • Engine coolant concentrates for heavy-duty applications

    3. Resin Modification for Foundry Binder Systems

    Foundry resin manufacturers utilize furfurylamine in the modification of furan resins, enhancing strength and chemical resistance of sand binders. The amine provides reactive sites, which contribute to improved crosslinking during the curing process, especially in acid-catalyzed systems used for automotive and machine casting.

    Industry compliance standards

    • ISO 17816:2019 – Foundry sand testing for furan resin binders
    • EN 46002 – Safety and occupational health standards for foundry additives
    • Compliance with REACH for furan derivatives

    Typical usage ratio

    • Addition ranges from 1–8% by weight of total resin blend; the exact loading depends on sand properties and desired mechanical strength of the molds.

    Downstream process integration

    • Introduced during pre-mixing with furan or phenolic resins, followed by acid catalysis and sand blending in foundry mold production lines.

    Final product types

    • Core and mold binders for metal casting
    • High-strength foundry molds for automotive and industrial castings

    4. Synthesis of Agricultural Chemical Intermediates

    Agrochemical companies rely on furfurylamine to manufacture intermediates for herbicides and plant growth regulators. Its reactivity supports the formation of N-heterocyclic structures and nitrogenous ligands, which serve as key scaffolds for effective active ingredients in crop protection products.

    Industry compliance standards

    • FAO/WHO Guidelines for pesticide formulation quality
    • EU REACH Regulation on intermediate use and registration
    • U.S. EPA 40 CFR Part 158 – Data requirements for registration of agricultural chemicals

    Typical usage ratio

    • Used at 0.8–1.7 mole equivalents per coupling reaction; fine-tuned by structure–activity relationship studies and regulatory maximum residue levels.

    Downstream process integration

    • Amine coupling and cyclization steps in the synthesis of pre-emergence or systemic agrochemical actives.

    Final product types

    • Pesticide and herbicide intermediates
    • Active plant growth regulator molecules
    • Technical concentrate products for crop protection

    5. Formation of Furfurylamide Monomers for Polymer Synthesis

    Specialty polymer producers convert furfurylamine to furfurylamide derivatives, which act as monomers or co-monomers in high-performance polymer systems. This route supports the generation of thermally and chemically stable polymers used in molding compounds and engineering plastics, delivering specific electrical or barrier properties via the incorporation of furan-based units.

    Industry compliance standards

    • ISO 9001 – Quality management systems for chemical manufacturing
    • RoHS compliance for electrical and electronic applications
    • Customer-specific QC testing for polymer monomer purity

    Typical usage ratio

    • Reactive loading between 15–30% by weight in polymerization bulk mix, adjusted for thermal stability and processing viscosity targets.

    Downstream process integration

    • Condensation or polycondensation with diacid chlorides or isocyanates, followed by melt or solution polymerization.

    Final product types

    • Engineering resins and thermosetting plastics
    • Insulation components for electronics
    • Barrier films for packaging

    6. Manufacturing of Biobased Solvents and Extractants

    Producers of specialty solvents and green extractants employ furfurylamine to synthesize novel, bio-derived solvent molecules. The amine group allows selective conversion into functionalized derivatives suitable for metal extraction, organic phase transfer, or formulation of environmental-friendly cleaning agents for electronics and precision industries.

    Industry compliance standards

    • OECD Guidelines for Testing of Chemicals – Biodegradability and ecotoxicity
    • TSCA inventory for market entry in the U.S.
    • ISO 14001 – Environmental management systems in chemical production

    Typical usage ratio

    • Synthesis typically consumes 1.0 equivalent per active solvent molecule; variations depend on functionalization degree and target application.

    Downstream process integration

    • N-alkylation, acylation, or further furan ring modifications; final blending and purification for direct use as extractant or solvent.

    Final product types

    • Bio-based polar solvents
    • Metal extractant additives
    • Precision cleaning agents for electronics, optics, or specialty equipment

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    Certification & Compliance
    More Introduction

    Furfurylamine: Behind the Scenes at the Plant

    Every batch of furfurylamine that leaves our facility represents months of work—from sourcing furan raw materials to perfecting the amination process that gives this chemical its unique profile. For decades, furfurylamine has had an essential place in the synthesis of tailor-made pharmaceuticals, resins, and agricultural solutions. We see the ripples of our work in lab notebooks, factory floors, even in ongoing university research projects. The product flows from the drum into finished goods that people use every day, but it’s the process, the chemistry, and the craftsmanship behind making high-purity furfurylamine that make the difference.

    What Sets Our Furfurylamine Apart

    From the ground up, we design our processes to create furfurylamine that meets strict analytical targets—whether those requirements are for a global pesticide brand or a new biopolymer innovation. Working with furan-based chemistry brings unique production challenges not everyone in the business tackles. The molecule—C5H7NO—features an aromatic furan ring, which makes it more reactive and more interesting for manufacturers looking for building blocks that do more than the ordinary.

    Standard routes bring their own headaches: managing side products, eliminating aldehyde carry-over, and handling the specific odor profile characteristic of furfuryl derivatives. Not all plants invest in distillation controls to keep residual water and by-products within parts per million, but we do. We match our batch records to each customer's lot-based needs, and keep samples from every product packed for long-term quality reference. Certain applications—especially in pharmaceuticals and fine chemicals—demand a furfurylamine that’s clear, low on color, and shows a narrow boiling range. Many clients who previously relied on overseas commodity suppliers have rerouted their sourcing after running into unpredictable quality and inconsistent amine nitrogen values.

    From Lab Bench to Warehouse Drum

    Production of furfurylamine isn’t simple. The process requires careful choices at every step, starting with purification of the furan feedstock. Residual furfural affects downstream reactivity, so targeted hydrogenation at set pressures is crucial. In practice, even a 0.2% difference in furfural content in the amine affects resin synthesis or pharmaceutical intermediates. We maintain granularity in monitoring every step. Our in-house analytical team evaluates by refractive index, gas chromatography, and colorimetric nitrogen titration. For certain customers, we report amine values down to the fourth decimal.

    For resin makers, the final color of furfurylamine often determines overall acceptance. Higher purity reduces the risk of off-spec polymerization or discoloration. The pharmaceutical field demands not just purity—chloride and secondary amine residuals must fall beneath trace detection. Storage practices also matter: glass-lining of tanks, moisture controls, and nitrogen blanketing preserve shelf-life far beyond generic grades.

    Typical Model and Specifications

    Our core furfurylamine model is formulated to meet minimum 99.0% by GC assay, a value most directly cited in pharmaceutical intermediate synthesis protocols. Water content stays below 0.2%, and, through proprietary distillation, we keep total amine impurities beneath 0.3%. The appearance under ambient temperature is clear, colorless to lightly straw, with less than 20 Hazen units. Specific gravity at 20°C ranges from 1.08 to 1.10, though we certify and record actual lot gravities for every outbound shipment.

    We maintain operating capacity to fill customer orders in 200 kg drums, 1MT IBCs, or custom-packed volumes. Each batch is tagged with manufacturing information traceable back over five years, and every container is filled under closed nitrogen atmospheres. Safety labeling and shipping documentation meets all responsible care protocols under current international transport guidelines.

    From Our Plant to Real Applications

    Where does this product show its strength? Take a look beneath the surface at plants making furfuryl alcohol-formaldehyde resins—furfurylamine acts as a crucial hardener and cross-linker. Its precise reactivity allows resin processors to control cure rates for everything from corrosion-resistant linings to advanced foundry binders. In specialty applications such as aramid fiber manufacture, operators prefer furfurylamine for its ease of functionalization and lower hazard profile compared to aliphatic amines.

    On the pharmaceutical side, several API intermediates rely on furfurylamine as the amination reagent of choice. Its furan ring paves the way to build substituted heterocyclic scaffolds, often unlocking molecular scaffolding not accessible with linear amines. As agricultural formulation shifts away from certain legacy actives due to regulatory changes, chemists reach for furfurylamine to build new actives with more selective reactivity and better environmental profiles.

    Comparisons to Other Amines

    What distinguishes furfurylamine from generic amines such as ethylamine or benzylamine? The furan ring introduces electron-rich reactivity, giving higher nucleophilicity in cyclization steps or ring-opening reactions. Ethylamine, methylamine, and others offer simplicity, but lack the complexity required for heterocycle assembly. Benzylamine brings aromatic stability, but without the oxygen functionality of furan, certain syntheses fail or require harsher conditions leading to lower yield and more by-products.

    Our own experiences with customers show clear boundaries: processes built around furfurylamine can reach higher final yields, especially for fine chemicals and specialty resins. One example: a global coatings manufacturer recently replaced their previous amine with furfurylamine, cutting side product formation by over 20% and improving shelf-life by several months. Lab trials for pesticide active synthesis gain more selectivity in C–N bond formation, making furfurylamine attractive for greener, cleaner chemistry. The combination of aromatic reactivity and nitrogen functionality also lets manufacturers bridge between oxygenated and aminated intermediates in a single synthetic route—reducing waste and shortening manufacturing timelines.

    Real-World Quality Challenges and Solutions

    Customers who’ve relied on furfurylamine from less consistent sources often report batch-to-batch variability. We’ve seen competitors dilute content or allow high furfural residues—problems that show up fast in downstream applications. Too much furfural increases color, causes off-odors, and triggers instability. To solve this, we established triple-point analytical validation with redundant GC columns and confirmatory titrations for each batch, not just one sample per production run.

    During a recent technical audit, we worked with a major resin producer facing unexplained batch failures. Our team traced the problem back to a competitor’s delivery—furfurylamine with residual water over 0.7%, never disclosed in official paperwork. They changed suppliers, shifting to our process control system, and saw defect rates drop immediately. These kinds of results aren’t accidental. They come from decades of know-how, relentless process audits, and a commitment to transparency.

    Keeping Workers and Communities Safer

    Manufacturing furfurylamine brings important EHS responsibilities. The chemical’s odor threshold means even trace releases could affect indoor air, so we engineered our plant with closed-loop fume scrubbing and stack monitoring. Our people undergo specialized hazard response training, and we invest in repeated internal audits. Emergency response plans include regular drills and partnerships with local responders—because custody of hazardous chemistry never ends at the factory fence.

    Handling waste from furfurylamine processes took years to optimize. Our site now recycles reaction wash water for use in on-site boiler cycles, reducing chemical oxygen demand (COD) in outgoing effluent by over 60%. We recover solvents and minimize packing waste by collaborating with customers on reusable container systems. Lessons from regulatory updates—especially TSCA and REACH—push us to document containment and emissions, an approach we share in open supplier audits for major accounts.

    Raw Material Sourcing and the Impact on Supply

    Every kilo starts with furfural, largely derived from agricultural byproducts like corn cobs or oat hulls. We built relationships with agricultural suppliers to secure steady, sustainable furfural streams. As weather, crop patterns, and geopolitics shift, we constantly monitor supplier chains. In a drought, reduced feedstock availability leads to higher prices. Our team hedges supply risks by qualifying multiple raw material vendors and maintaining inventory buffers.

    Not all producers can adapt quickly to supply chain shocks. Some competitors switch to lower-grade feedstocks, sacrificing purity to keep product on the market. We resist that temptation—because every change at the front end multiplies at the back. What we make is only as good as the raw materials that go into it. We’ve fielded emergency inquiries from global users unable to meet compliance after sourcing off-shore. Close relationships with our furfural producers—some going back more than twenty years—insulate us against these kinds of disruptions, letting our customers finish their own products without delays or hiccups in purity, even during unstable market conditions.

    Working Directly with R&D Teams

    As a true manufacturer, we collaborate with users who need more than a commodity. Researchers in fine chemicals frequently run up against synthetic dead ends because standard amines don’t play well in custom syntheses. Our team provides tailored support—helping labs scale small-batch runs, offering feedback on possible impurities, even supplying special grades for validation runs. Sometimes, our involvement helps solve tough problems, like limiting odor transfer in finished materials or extending the shelf life of amine-containing blends. We share technical packages showing trace impurity profiles and answer questions about reactivity, helping development chemists make informed choices about next-generation products.

    Regulatory Demands and Product Compliance

    Increasing standards for quality and safety bring regular scrutiny. Leading global end users now require furfurylamine that fits not just their specification sheets, but also regulatory and sustainability audits. Our plant’s quality systems run to ISO 9001, with every lot documented through batch production, sampling, and release. We track all inputs, outputs, and tie every analytical record to training and oversight logs, regularly verified by third parties. When customers from the EU or North America ask for full documentation—including site hazard assessments and material traceability—they find nothing lost in translation. As global disclosure standards evolve, we update our practices to reflect the latest expectations, from GHS labeling to residual solvent declarations.

    Environmental Stewardship: Making Chemistry Safe by Design

    Chemical manufacturing’s future depends on more than compliance. The shift toward green chemistry and safer production means rethinking each step. For furfurylamine, that begins with capturing all fugitive emissions and finding new ways to reuse or destroy hazardous by-products. The researchers and plant operators at our facility treat sustainability not as an add-on but as a priority embedded in daily routines. By investing early in closed-loop designs and leak detection systems, we have proven that chemical safety and commercial viability go hand-in-hand.

    Auditors visiting our site routinely comment on our investment in people and systems—a recognition that comes only after decades of doing the right thing, even when no one is watching. We remain transparent with annual sustainability disclosures, inviting partners to understand exactly how our processes work and how we plan to improve into the future.

    Industry Trends and the Future of Furfurylamine

    Growth in biodegradable polymers, shifting pesticide regulations, and the emergence of high-performance resins are all expanding the role of furfurylamine in chemical innovation. Not every player can meet evolving demands for higher purity or tighter tolerances, which sets established manufacturers apart from short-term traders. While global demand for furan-based intermediates grows, we adapt processes to serve both longstanding bulk requirements and rapidly changing specifications from specialty segments.

    We engage with trade associations, standards bodies, and technical consortia to remain at the forefront, sharing our expertise through published work and contribution to industry best practices. As new applications emerge—such as targeted drug delivery technologies or low-toxicity polymer networks—our technical teams work on the front lines to ensure our product specification evolves in tandem with industry advances, always grounded in the basics: high-purity product, transparent practices, and absolute reliability.

    Furfurylamine: Expertise You Can Rely On

    Making furfurylamine well requires more than running a reactor—it takes a commitment to detail, deep chemical experience, and partnership with every link in the supply chain. The quality, consistency, and safety standards we have developed reflect decades of continuous improvement, grounded in real-world responsiveness to customer needs and tighter global benchmarks. Our site teams, from operators to researchers, bring the knowledge and care that modern furfurylamine production demands. Every shipment is built on a foundation of chemical expertise and a determination to deliver only the best, proving that effective manufacturing is still driven by people who know their work and care about its impact far beyond the gates of the factory.

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