Cyclopentanone

    • Product Name: Cyclopentanone
    • Alias: Ketocyclopentane
    • Einecs: 206-001-3
    • Mininmum Order: 1 g
    • Factroy Site: Yudu County, Ganzhou, Jiangxi, China
    • Price Inquiry: admin@ascent-chem.com
    • Manufacturer: Ascent Petrochem Holdings Co., Limited
    • CONTACT NOW
    Specifications

    HS Code

    483037

    Chemical Name Cyclopentanone
    Cas Number 120-92-3
    Molecular Formula C5H8O
    Molar Mass 84.12 g/mol
    Appearance Colorless liquid
    Odor Peppermint-like odor
    Melting Point -51°C
    Boiling Point 130.6°C
    Density 0.949 g/cm³ at 20°C
    Solubility In Water Moderate (15 g/L at 20°C)
    Flash Point 31°C (closed cup)
    Refractive Index 1.447 at 20°C
    Vapor Pressure 11 mmHg at 20°C
    Explosive Limits 1.1–9.3% (in air)
    Autoignition Temperature 400°C

    As an accredited Cyclopentanone factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Cyclopentanone is packaged in a 500 mL amber glass bottle with a tightly sealed cap, labeled with hazard and safety information.
    Shipping Cyclopentanone should be shipped in tightly sealed containers, kept cool, dry, and well-ventilated. It must be classified as a flammable liquid (UN 2245), and transported according to local, national, and international regulations. Avoid exposure to ignition sources, heat, and direct sunlight. Containers should be clearly labeled and handled with appropriate safety precautions.
    Storage Cyclopentanone should be stored in a tightly closed container in a cool, dry, and well-ventilated area, away from sources of ignition and incompatible substances such as strong oxidizers and acids. Keep it away from direct sunlight and heat. Use appropriate explosion-proof equipment and ensure proper labeling. Store at room temperature and avoid excessive moisture and extreme temperature fluctuations.
    Application of Cyclopentanone

    Applications of Cyclopentanone in Industrial Manufacturing

    Cyclopentanone serves as an essential intermediate for numerous chemical production routes in large-scale industries, especially where precise molecular structure control and high chemical purity are required. As a direct manufacturer, we provide this raw material to certified downstream plants for specific regulated applications, ensuring consistency in both process integration and compliance management. The following sections detail recognized application scenarios supported by industry documentation, process data, and end-user feedback across the chemical, pharmaceutical, and technical materials sectors.

    1. Agrochemical Synthesis Intermediates

    Large-scale crop protection product manufacturers utilize cyclopentanone within multi-step organic synthesis routes to construct active compounds such as insecticides and fungicides. This production step leverages cyclopentanone’s reactivity with nucleophiles and halogens, making it a vital component for ring enlargement, condensation, and introduction of functional groups essential for biological activity. Batch documentation systems and process analytical technologies track each addition to ensure efficient conversion and minimal byproduct formation.

    Industry compliance standards

    • ISO 9001:2015 Quality Management for chemical intermediates
    • REACH Regulation (EC) No 1907/2006 for registration and safe handling
    • FAO/WHO Technical Specifications for active substances in crop protection
    • Product stewardship guidelines as outlined by the European Crop Protection Association (ECPA)

    Typical usage ratio

    • 5–20% by molar input in initial condensation or ring modification steps; percentage varies based on targeted active ingredient synthesis, adjusted to molecular yield and purity requirements

    Downstream process integration

    • Introduced during the key intermediate coupling or cyclization under controlled temperature and catalytic conditions; employed prior to final formulation and purification of the active substance

    Final product types

    • Pyrethroid insecticides (e.g., lambda-cyhalothrin intermediates)
    • Fungicide active components (e.g., triazole precursor synthesis)
    • Herbicide intermediates for diversified application
    • Crop protection specialty chemicals

    2. Pharmaceutical API & Intermediate Manufacturing

    Producers of active pharmaceutical ingredients select cyclopentanone when building complex cyclic structures due to its reliable reactivity in aldol condensation and reduction reactions. Its controlled integration allows downstream partners to synthesize pharmaceutical intermediates that comply with pharmacopoeia-grade standards. Processing usually occurs in closed systems, and supporting analytical methods confirm batch identity and track trace impurity levels to support regulatory submissions.

    Industry compliance standards

    • Good Manufacturing Practice (GMP, ICH Q7)
    • United States Pharmacopeia (USP), European Pharmacopoeia (Ph. Eur.) standards
    • FDA Drug Master File (DMF) registration guidance
    • ISO 13485 for medical raw material supply chain

    Typical usage ratio

    • 2–15% by weight per synthesis step, frequently optimized to achieve reactivity while limiting carryover; formulation specifics follow process development and impurity profile management

    Downstream process integration

    • Participates directly in condensation reactions to create key intermediates for antiviral, analgesic, or cardiovascular APIs; subsequent steps involve extraction, crystallization, and salt formation to finalize API structure

    Final product types

    • Intermediate compounds for antiretroviral agents
    • Skeletal muscle relaxant synthesis precursors
    • Bicyclic or spirocyclic pharmaceutical intermediates
    • Small molecule drugs requiring rigid cyclic groups in their core structure

    3. Fragrance and Flavor Ingredient Synthesis

    Manufacturers of specialty fragrance and food flavorings incorporate cyclopentanone to build complex aroma compounds with cyclopentyl functional groups, valued for imparting sweet, minty, or camphor-like notes. Analytical quality control and cleanroom blending ensure each production batch meets international requirements for trace contaminants, providing confidence to major perfumery and food additive clients.

    Industry compliance standards

    • IFRA (International Fragrance Association) Guidelines
    • EU Regulation (EC) No 1334/2008 on flavorings
    • Food Chemicals Codex (FCC)
    • ISO 9001 for quality management in food additive supply

    Typical usage ratio

    • 0.5–4% by volume in aroma synthesis steps; proportion tailored according to the target scent note intensity and final product compound purity

    Downstream process integration

    • Blended with aldehydes and alcohols under controlled conditions to craft core intermediates; subsequent distillation and fractionation isolate pure aroma substances

    Final product types

    • Menthone and related mint-flavored perfume ingredients
    • Cyclopentyl-cored fruity flavor additives
    • Specialty aroma chemicals for luxury perfumery
    • Fine blended notes for high-end cosmetic fragrances

    4. High-Performance Solvents for Specialty Coatings

    Industrial coatings and adhesives producers select cyclopentanone for solvent or co-solvent use in advanced resin systems, particularly where solvent evaporation rate and compatibility influence film formation and curing. In polyurethane and specialty polymer coatings, it enhances viscosity control without introducing unwanted impurities. Process validation protocols check solvent purity at input and after mixing, ensuring low residue and consistent batch properties.

    Industry compliance standards

    • ISO 12944 for protective paint systems
    • ASTM D5402 for chemical resistance testing in coatings
    • VOC regulations (US EPA 40 CFR Part 59, EU Decopaint Directive 2004/42/EC)
    • REACH registration for safe solvent handling

    Typical usage ratio

    • 10–35% by weight of total solvent blend; ratio fine-tuned to resin type, desired evaporation profile, and film thickness

    Downstream process integration

    • Added at resin mixing or pre-polymerization stage as a carrier solvent; helps dissolve polymers and modulate drying curve during film application and curing

    Final product types

    • Solvent-based PU coatings for automotive and industrial finishes
    • Specialty adhesives for electronics assembly
    • Protective coatings for machinery and infrastructure
    • High-gloss varnishes and specialty ink formulations

    5. Electronic Chemical Processing Additives

    The electronics sector incorporates cyclopentanone in select photoresist formulations and as an etching process additive for microfabrication. Its solvent behavior supports the uniform application of organic and hybrid functional layers during wafer production. Tight quality surveillance provides product traceability, tracking every shipment according to batch number and supporting detailed materials management in compliance-driven facilities.

    Industry compliance standards

    • SEMI (Semiconductor Equipment and Materials International) purity standards
    • ISO/TS 16949 for electronics chemical suppliers
    • RoHS Directive (2011/65/EU) for hazardous substances
    • IEC QMS and ISO 9001 certified supply chains

    Typical usage ratio

    • 3–12% by weight in resist and additive blends; process engineers modify ratios to match coating thickness and step coverage requirements

    Downstream process integration

    • Introduced into photoresist formulation tanks or in cleaning baths prior to lithography; product control includes in-process solvent monitoring and real-time contamination checks

    Final product types

    • Photoresist solutions for PCB and IC wafer manufacturing
    • Microelectronic device patterning materials
    • Etching additives for semiconductor wafer fabrication
    • Lubricant carriers for HDD production lines

    6. Polymer Modification and Engineering Plastics

    Processors specializing in advanced polymers employ cyclopentanone as a reactive solvent and monomer precursor for rings in engineering plastic matrices, particularly where cyclopentyl groups support desired mechanical or thermal performance. Production departments monitor solvent ratios and reaction temperatures to optimize polymer chain structure, supporting the scaling of specialty resins for critical use sectors.

    Industry compliance standards

    • ISO 17855 for polyamide and engineering plastics
    • EN 10204 material certification for downstream plastics
    • REACH compliance for monomer and polymer additives
    • ISO 9001:2015 for quality-controlled resin output

    Typical usage ratio

    • 2–8% by weight during pre-polymerization; ratio varies based on desired cyclopentyl incorporation and resin architecture

    Downstream process integration

    • Dosed with primary monomers or directly during melt blending and extrusion; supports in-line chain extension or branching modifications

    Final product types

    • Heat-resistant specialty polyamides
    • Cyclopentyl-modified thermoplastic resins
    • Technical plastics for aerospace components
    • Polymer films for high-temperature filtration

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    Certification & Compliance
    More Introduction

    Cyclopentanone: Manufacturer’s Insights and Hands-On Experience

    Understanding Cyclopentanone from Our Production Lines

    Cyclopentanone holds an important slot in our production schedule. Unlike several other simple ketones, it carries a five-membered ring structure, lending it properties that find use across fragrances, pharmaceuticals, and specialty chemicals. Our facility has manufactured Cyclopentanone for years, and experience has shaped the way we approach its synthesis, handling, and delivery. A solid grasp of its unique physical and chemical traits lets us serve users who look for reliability, repeatability, and efficiency.

    Our Manufacturing Approach

    Every batch starts in reactors built to withstand both the pressure and temperature swings essential for single-step and multistep syntheses. We employ processes primarily built upon the oxidation of cyclopentanol, as this route reliably gives high yields and consistent purity, minimizing waste streams. Each run undergoes close monitoring for temperature profiles and conversion rates, and every intermediate is screened for contaminants before progressing. The system integrates modern controls—feedback loops manage flow rates, energy consumption, and emissions.

    For purification, we use fractional distillation and advanced filtration steps that capture residual byproducts and minimize organic load. Our operators know that slight variations at any stage can ripple into downstream performance issues or output drift. Decades in this industry show us where the pitfalls hide and teach us to recognize signals before they turn into real problems.

    Physical and Chemical Properties We Track

    Cyclopentanone (molecular formula C5H8O, CAS 120-92-3) presents as a clear, colorless liquid, with a mild, peppermint-like odor distinctive from its higher cyclic ketone relatives. Its boiling point sits at about 130°C, which places it above many low-chain ketones but below comparable cyclic ethers or amides. Its density and viscosity support high-speed blending into diverse reaction environments without phase separation.

    Solubility in water drops off sharply compared to acetone or methyl ethyl ketone, but Cyclopentanone delivers good compatibility with alcohols, ethers, and most non-polar solvents. This allows formulators to exploit its ring strain, influencing reaction rates and the selectivity of condensation, reduction, and cyclization processes.

    Purity Grades and Real-World Necessities

    We provide Cyclopentanone in industrial grades, lab-grade purities, and custom specifications for customers with critical downstream needs. Analytical routines on outlet streams cross-check for water content, color, and trace impurities—every shipment leaves with certificates reflecting batch-specific results, not generic guarantees.

    Years of feedback from fine chemical, agrochemical, and fragrance sectors tell us the boundary between acceptable and rejectable material can be razor-thin. Trace aldehydes or peroxides at parts-per-million levels sometimes interfere with downstream actives or final fragrance notes. To get ahead of these issues, our in-house labs screen for contaminants like cyclopentanol, cyclic dimers, and residual acids. We’ve refined our distillation protocols specifically to target these troublemakers, investing in cold traps and scrubbers as needs evolved.

    Usages: Lessons Learned from Downstream Applications

    Many customers reach out early in their formulation development, seeking technical input that emerges only from time on the plant floor. Cyclopentanone works as a core intermediate for the synthesis of pharmaceutical precursors and specialty aroma chemicals. Its five-member ring, bearing a reactive carbonyl group, offers synthetic chemists a chance to create unique scaffolds.

    Perfumers particularly value the compound for its subtle cooling and minty notes. In-house applications studies and real stories from fragrance teams reveal that trace solvent impurities or even slight variations in water content can dull or distort the resulting product. Over the years, these customers have requested tighter cutoffs on specific impurity classes—often below routine industrial standards.

    Agrochemical firms, another cornerstone of our customer base, count on Cyclopentanone for introducing cyclopentyl groups into active ingredients and intermediates. Here, unaddressed peroxides or residual alcohols can trigger unwanted byproducts, limits on process yields, or regulatory headaches during material audits.

    What Makes Our Cyclopentanone Distinct

    The workplace habits around cyclic ketones grew from experience—years in the same manufacturing buildings. Cyclopentanone may look like a close cousin to cyclohexanone or methyl ethyl ketone, but on the factory floor, each brings a distinct set of challenges and operational realities. Cyclopentanone’s reactivity profile does not line up with its relatives—its ring strain often speeds up specific organic reactions, but its slightly lower boiling point means a heightened risk of vapor losses if temperature control drifts.

    Cyclopentanone also attracts water, but does not solubilize as freely as acetone. Each week, teams check storage vessels for condensation build-up and water ingress because hydrolyzed product dulls performance, clouds the appearance, and can trouble customers using it as a fragrance feedstock. The obvious odor difference between Cyclopentanone and higher homologs also means trace contaminants from line cross-contamination, like cyclohexanone or cyclopentanol, can throw off both downstream syntheses and scent profiles in odor-critical applications. We set aside unique storage, dedicated transfer lines, and specific QA checks that segregate this product from others.

    Continuous Improvements: How We Adapt to New Standards

    Tighter environmental controls and rising industry standards push us further each year. Air and water discharges from Cyclopentanone production present a completely different profile from bulk ketones or acetone streams. Years ago, standard filtration could not always contain all minor contaminants, and operators had to mop up equipment leaks or vapor losses. Today’s monitors detect even small spikes instantly, and in-house engineers design vapor and effluent management systems as a critical step—emissions do not become an afterthought.

    Recent experiences with customer audits also push for higher compliance checkpoints at every step. Third-party testing aligns with internal results, supporting both regulatory updates and customer-driven change requests. Pharma and fragrance customers routinely audit our data and approach, so in response, our traceability workflow documents each reactor charge, pressure test, and sampling run. Simple paper logs gave way to electronic records—less guesswork and clearer results when a problem arises.

    We stay receptive to specification changes or feedback from users in the field. Some end-users discover that packaging residuals, if not cleaned properly, show up in their analytical profiles even if the bulk product passes all our standard tests. In response, packaging lines switched over to inert liners and air-purged closures for certain customers.

    Differences Beyond the Datasheet: What Users Should Consider

    Datasheets and technical bulletins rarely tell the whole story. Cyclopentanone works very differently from its six-carbon cousin, cyclohexanone, or mainstream solvents such as acetone. In real-world chemical plants, similar boiling points can hide big divergences in volatility, odor, and the way water contamination creeps in. A process line designed for bulk ketones often struggles to control evaporation losses with Cyclopentanone, especially if vent controls are set up for higher-boiling relatives.

    The ring structure means the molecule behaves differently in reductions or cross-condensations compared to open-chain ketones. An operator switching from one to the other cannot simply substitute Cyclopentanone without considering new side reactions or shifts in processing times. Storage tanks lined for more aggressive ketones sometimes over-engineer for Cyclopentanone, but experience tells us the main vulnerabilities lie in exposure to air and accidental introduction of bases or acids—each triggers decomposition or odor drift. Our teams have seen how years-old tanks and lines, if not flushed carefully, can leach traces from earlier materials, resulting in unexpected off-odors or color development.

    Feedback showed us that the physical handling of Cyclopentanone sets it apart from bulk commodity solvents. Both supply chain and end-users note the difference when unloading drums or tote tanks—a slightly lower vapor pressure means less risk of flash-off during transfer, but greater sensitivity to temperature swings. We train drivers, warehouse teams, and plant operators on specific procedures, both to avoid environmental release incidents and to ensure customers receive product without quality drift.

    Packaging Decisions: What Years of Feedback Drove Us To Do

    Our packaging strategies reflect lessons from repeated customer feedback and real mishaps in transit. Early attempts with generic HDPE barrels allowed moisture seepage in humid regions, so container liners and drum seals received upgrades. Now Cyclopentanone leaves our gates in steel drums, lined totes, or bulk ISO containers based on volume needs. Each package carries individual seals and tamper indicators, matched to the requirements of high-purity and technical grades. We stamp each with batch codes and full traceability keys—no exceptions.

    Customers raised concerns over cross-contaminant build-up when supply runs alternate between similar but not identical cyclic solvents. To answer, we now assign dedicated lines, use third-party cleaning for returnable containers, and offer on-site audits. These adjustments remove variables, letting us guarantee the same Cyclopentanone quality with each order. Even the best-in-class cyclic ketone can lose value fast if contamination or packaging flaws go unchecked.

    Customers needing tailored lot sizes, whether from scale-up or pilot projects, find additional support on request. Logistics planners on our end advise ahead of any project requiring tighter windows or special handling requirements. These include winterized shipments for extreme cold and rapid delivery for regulated pharma trials.

    Health, Safety, and Worker Practices Across Years

    Hands-on familiarity with Cyclopentanone makes a difference—not just in the lab, but on plant floors. Vapors can irritate, requiring proper local exhaust and PPE at all handling points. Years of monitoring show that properly maintained ventilated cabinets and scrubbers prevent most exposure incidents. Frequent air sampling and personal dosimetry keep records honest and point out when procedures need tightening up.

    Direct contact with skin causes moderate irritation, so we train every new operator and require barrier gloves and splash shields at all drum-filling and transfer points. Years ago, minor spills on warehouse floors sometimes left odors lingering for days. Adjustments include spill kits at regular intervals, rapid-response procedures, and dedicated staff training. We notify all supply partners about required storage temperatures and the importance of keeping container seals intact from receipt through to use.

    Some customers ask about chronic exposure risks or environmental profiles. Our in-house hazard communication links to published toxicological and environmental data: Cyclopentanone breaks down in the environment more quickly than longer-chain or aromatic ketones, but local conditions, disposal routes, and regulatory rules vary. All shipments leave with clear hazard and storage labels, and our technical support advises on any special regional or industry guidance available at the time.

    Sustainability, Waste Minimization, and Future Directions

    Manufacturing Cyclopentanone responsibly shapes our daily routines and long-term investments. Years of experience showed us that minor byproduct recovery can minimize total waste and turn side streams into value, rather than disposal costs. Every distillation sequence now collects heavy ends, spent solvents, and water washes for recycling or reprocessing. Our teams monitor solvent usage rates, and process engineers tweak cycles regularly to reduce fresh solvent demand while maintaining product integrity.

    Emerging green chemistry protocols influence our catalyst selection and energy use planning. In recent years, demand for bio-based or lower-carbon footprint Cyclopentanone has grown. Although process economics remain a challenge at scale, we’ve run pilot plants with alternative feedstocks such as renewable cyclopentanol and reviewed vendor claims for enzyme-based oxidations. In both cases, commercial uptake remains limited, but early results show promise for future implementation. Our experience tells us real change in industrial chemistry happens incrementally, through constant evaluation, pilot runs, and open engagement with users.

    We correspond with regulatory bodies and industry networks to stay ahead of both new environmental expectations and evolving customer needs. Longstanding relationships with analytical labs and academic partners support method development and third-party evaluation. We trust data, not just company line—each year, new compliance or end-use requirements feed back into process review and capital improvement plans.

    Our Promise: Accountability Built Through Years of Manufacture

    Trust in Cyclopentanone, like any specialty chemical, grows from consistent quality, open feedback, and familiarity with the molecule’s quirks in real-world use. Our operators, engineers, and customer support teams draw on decades of accumulated knowledge. Whether a client develops a new pharmaceutical intermediate, fragrance, agricultural treatment, or specialty material, we speak from direct experience on what to expect and how to minimize risks.

    Difference emerges not just from purity certificates or technical claims but in the willingness to troubleshoot, document, and stand behind each delivery. Batch histories, corrective actions, and user training documents all evolve from on-the-ground realities. Success measures itself in repeat orders, transparent communications, and customer referrals—not just in shipping volumes or brochure claims.

    Cyclopentanone serves many markets, but working as a manufacturer puts us squarely in touch with the changing needs and challenges that customers face. We do not see the work ending at product delivery—the cycle includes process innovation, proactive problem-solving, and support long after material leaves our gate. This attitude, shaped by years at the reactor and along the loading dock, defines our contribution to both chemistry and commerce.

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