Cycloheptane

    • Product Name: Cycloheptane
    • Alias: Heptanaphthene
    • Einecs: 203-624-3
    • Mininmum Order: 1 g
    • Factroy Site: Yudu County, Ganzhou, Jiangxi, China
    • Price Inquiry: admin@ascent-chem.com
    • Manufacturer: Ascent Petrochem Holdings Co., Limited
    • CONTACT NOW
    Specifications

    HS Code

    870614

    Chemicalname Cycloheptane
    Molecularformula C7H14
    Molarmass 98.19 g/mol
    Casnumber 291-64-5
    Appearance Colorless liquid
    Odor Mild, gasoline-like
    Meltingpoint -12 °C
    Boilingpoint 118 °C
    Density 0.813 g/cm³ at 20 °C
    Solubilityinwater Insoluble
    Flashpoint 22 °C (closed cup)
    Vaporpressure 8.96 kPa at 25 °C
    Refractiveindex 1.439 at 20 °C

    As an accredited Cycloheptane factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing A 500 mL amber glass bottle labeled "Cycloheptane," featuring hazard symbols, chemical information, lot number, and a secure screw cap.
    Shipping Cycloheptane is shipped as a flammable liquid, typically in sealed metal drums or approved containers to prevent leaks and vapor release. It should be transported under cool, dry conditions, away from heat, ignition sources, and oxidizing agents. Proper labeling and adherence to international shipping regulations for hazardous materials are required.
    Storage Cycloheptane should be stored in a tightly closed, properly labeled container in a cool, dry, and well-ventilated area, away from heat sources, sparks, open flames, and incompatible materials such as oxidizing agents. It should be kept away from direct sunlight and static discharge. Appropriate safety precautions and grounding should be observed to prevent fire or explosion, as cycloheptane is highly flammable.
    Application of Cycloheptane

    Applications of Cycloheptane in Industrial Manufacturing

    Cycloheptane plays highly specialized roles in a range of chemical industry sectors, supporting process performance and product integrity across regulated downstream production. As a chemical manufacturer, we supply cycloheptane specifically for applications that demand strict compliance and precise integration into customer formulations. Below, we outline real-world application segments, focusing on compliance, process workflows, typical concentrations, and the finished products manufactured by our clients.

    1. Pharmaceutical Synthesis: Solvent for API Intermediates

    Cycloheptane’s defined non-polarity and narrow boiling range enable its use as an extraction and crystallization solvent in high-value active pharmaceutical ingredient (API) synthesis, particularly for intermediates sensitive to water or other more polar hydrocarbons. Process engineers select it where tight residual solvent controls are critical, ensuring high-purity isolation during multi-step organic synthesis, in line with both official pharmacopeial and customer-specific guidelines.

    Industry compliance standards

    • ICH Q3C (Residual Solvents)
    • USP <467> Organic Volatile Impurities
    • Good Manufacturing Practice (GMP), EU and FDA cGMP
    • Client-specific quality agreements (monographs, in-house specs)

    Typical usage ratio

    • 5–30% volume/volume in reaction/extraction phases, modulated by intermediate solubility and required recovery efficiency; final ratio determined by API route specificity and regulatory solvent limits.

    Downstream process integration

    • Solvent charging takes place after in-situ formation of organometallic or halogenated intermediates.
    • Used during fractional crystallization, followed by vacuum distillation for solvent removal and potential recycle.
    • Integrated into closed-loop mixing vessels to avoid cross-contamination.

    Final product types

    • Active pharmaceutical ingredients (APIs), such as certain cephalosporins and macrocyclic drugs
    • Key reaction intermediates for branded and generic pharmaceuticals

    2. Analytical Laboratory Reference Materials

    Cycloheptane, due to its stable non-aromatic structure and well-defined purity profile supported by our QC, is widely used as a calibration standard, diluent, and matrix solvent for gas chromatography (GC) and high-performance liquid chromatography (HPLC), primarily in testing regimes where interference from aromatic hydrocarbons must be strictly avoided. Our material is supplied with comprehensive CoA supporting analytical traceability and batch-specific impurity data.

    Industry compliance standards

    • ISO/IEC 17025 (Testing Laboratory Accreditation)
    • ASTM D3606 (Aromatics Content by GC)
    • EPA 8260B/ EPA 624.1 (Volatile Organic Analysis in water and waste samples)

    Typical usage ratio

    • 1–10% as internal standard; amounts adjusted based on instrument method and target detection limits within laboratory SOPs.

    Downstream process integration

    • Laboratory personnel introduce as a calibration or matrix solvent for standard preparation during analytical method validation and routine quantification.
    • Direct addition into GC or HPLC vials prior to injection.

    Final product types

    • Certified reference standards for instrument calibration
    • Analytical report packages for environmental, petrochemical, or pharmaceutical samples

    3. Specialty Adhesives and Sealant Formulation

    Cycloheptane is a key carrier solvent and volatile component in certain moisture-curing polyurethane and synthetic elastomer adhesives, especially in scenarios where migration of aromatic residues must be completely avoided. In downstream adhesive plants, its fast and uniform evaporation profile optimizes initial tack while meeting strict VOC emissions and workplace exposure limits. Our shipments are supplied with detailed safety, handling, and impurity controls, supporting compliance in high-demand industrial assembly applications.

    Industry compliance standards

    • REACH (EU Regulation No 1907/2006)
    • OSHA PEL limits (29 CFR 1910.1000)
    • EN 13999-1 (Adhesive VOC Emission Standards)
    • Downstream user chemical safety assessment (DU CSA)

    Typical usage ratio

    • 10–20% by weight of adhesive batch; level tailored to desired solids content and application viscosity, balanced to maintain open time and film formation.

    Downstream process integration

    • Added during pre-blend or final compounding, prior to high-shear mixing of polymeric binders.
    • Evaporates during application or drying tunnel, concurrently reducing viscosity to application-grade.

    Final product types

    • Moisture-cure PU adhesives for automotive weatherstrips
    • High-strength assembly adhesives for footwear manufacturing
    • Sealant products for insulation panels and industrial gaskets

    4. Cycloalkane-Based Reference Fuels for Engine Testing

    Cycloheptane serves as a defined component in R&D and reference fuel blends used by engine and lubricant developers to characterize combustion behavior and antiknock properties in standardized testing. It is specifically chosen for its non-aromatic composition, facilitating precise study of cycloalkane influence in research octane number (RON) and motor octane number (MON) protocols. Our production ensures batch homogeneity and consistency, supporting reliable and repeatable results for automotive and lubricant laboratories.

    Industry compliance standards

    • ASTM D2699 (Research Octane Number)
    • ASTM D2700 (Motor Octane Number)
    • ISO 5164/ISO 5163 (Knock Characteristics of Motor Fuels)
    • ISO 17034 (Reference Material Producers)

    Typical usage ratio

    • 2–15% by total fuel volume, depending on the target composition for cycloparaffinic content specified for engine test protocols.

    Downstream process integration

    • Added to compositional blends during formulation of research reference fuels in test laboratories.
    • Blended under inert gas to prevent volatilization loss, followed by containerization in certified drums or cans for test use.

    Final product types

    • Reference gasoline and specialty fuel blends for engine calibration
    • Test fuels for octane rating studies and emissions research

    5. Polymerization Process Aid in Polyolefin Manufacturing

    In high-purity polyolefin resin plants, cycloheptane functions as an inert diluent and reaction medium during specialty Ziegler-Natta and metallocene-catalyzed polymerizations, where aromatic and certain linear alkane contaminants must be minimized. The cycloalkane structure ensures controlled viscosity and heat transfer characteristics, facilitating uniform particle formation and limiting undesired copolymerization side reactions. Our technical supply meets stringent hydrocarbon purity specifications as required for process reliability.

    Industry compliance standards

    • ISO 9001 (Quality Management Systems for Specialty Chemicals)
    • ASTM D4057 (Practices for Manual Sampling of Petroleum and Products)
    • Company- or joint-venture process specifications for catalyst compatibility

    Typical usage ratio

    • 20–40% weight of total reactor charge, precisely adjusted based on polymer grade and targeted melt index of the final resin.

    Downstream process integration

    • Charged as the initial diluent into polymerization reactors under controlled inert atmosphere.
    • Partially recycled after polymer recovery, with periodic purge to maintain impurity levels below threshold.

    Final product types

    • High-purity isotactic polypropylene pellets
    • Specialty polyethylene copolymers for film and molded components

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    Certification & Compliance
    More Introduction

    Cycloheptane: Essential Hydrocarbon for Reliable Chemical Synthesis

    Experience with Cycloheptane in Modern Manufacturing

    Cycloheptane enters the conversation among organic solvents because producers like us operate in settings where reliability, safety, and consistency carry more meaning than marketing promises. Over years of running batch processes and scaling up novel syntheses, our teams have come to appreciate how every subtle property of a solvent shifts outcomes downstream. Our Cycloheptane (CAS No. 291-64-5) has become a solid solution where moderate volatility, low reactivity, and ease of recovery matter as much as anything else in the workflow.

    Most of our output flows to customers who want stable, colorless liquids for formulations and synthesis runs. With a molecular formula of C7H14, Cycloheptane stands apart from lower alicyclic hydrocarbons in certain laboratory and plant settings. Distillation brings purity levels above 99.5%. We keep water content very low—typically below 100 ppm—to protect moisture-sensitive reactions and prevent unwanted hydrolysis. Infrared spectrometry checks for trace aromatics or unsaturated compounds before drum filling, since reliable results in downstream chemistry can hinge on these quiet details. Our internal purity controls grew tighter as pharmaceutical and specialty chemical producers raised their requirements.

    How Cycloheptane Standards Evolved through Practice

    Cycloheptane doesn’t take up headline space that more exotic ring systems do in texts or trade journals. Yet every synthesis chemist and coatings formulator on our team recognizes its particular fit. The seven-membered ring confers a boiling point (roughly 118°C) that falls right between familiar friends, Cyclohexane and Cyclooctane. That moderate volatility supports clear separation during distillation or solvent recovery, in contrast with branched or highly volatile hydrocarbons that call for extra cooling or tighter system seals.

    We do not overlook the significance of impurities. Over the years of repeated runs, we’ve tightened our purification processes to ensure hydrocarbons like methylcyclohexane or cyclohexane do not persist above low ppm levels, since their physical properties—boiling points, polarity, and UV absorption profiles—can distort both industrial and analytical outcomes. The increased regulatory and analytical scrutiny in recent years prompted new batch testing, so we know what actually reaches the customer is what came off the GC column in our own lab.

    Practical Roles and Performance in Real-World Processes

    Customers draw on Cycloheptane’s nonpolar nature for roles where aromatic content, stabilizer residues, and reactivity all must stay low. Our own experience in organic synthesis, whether running scale model reactions or preparing intermediates, shows it performs best where side reactions with oxygen, acids, or bases risk undermining product purity. Its ring structure offers escape from the unwanted reactivity sometimes triggered by double bonds or aromatic rings.

    In coatings and adhesives formulations, thin films produced using Cycloheptane show higher resilience against yellowing or haze formation—especially important if you’re aiming for clear, stable varnishes. Customers avoid aromatic-based solvents to cut down on workplace exposure limits, and here Cycloheptane checks the required boxes: high flash point, reduced skin absorption, and little tendency to promote photooxidation.

    Testing in analytical settings revealed another set of advantages. Our clients’ labs need eluents and calibration standards that cause neither ghost peaks nor instrument fouling. Cycloheptane remains stable under GC and HPLC conditions, evaporates fully, and avoids background signals that might confuse trace analysis—features that sound simple, but demand real effort to guarantee batch after batch.

    Comparing Cycloheptane with Related Alicyclic and Aliphatic Solvents

    Looking across our order history, customers often stack Cycloheptane against cyclohexane, n-heptane, and other lower alicyclic systems. The nuance comes from each molecule’s balance of volatility, solvency, and physical compatibility with modern process equipment. Cyclohexane brings a lower boiling point and sometimes outsells Cycloheptane by volume, yet it evaporates too fast for some applications and can creep into impurity profiles. N-heptane appears less prone to ring strain, but lacks the same film resilience or recovery rate after drying. Cycloheptane strikes a balance where volatility doesn't outpace handling speed and boiling point peaks above ambient but doesn’t require high-pressure steam. In complex systems, this balance allows our customers to engineer their product qualities more flexibly.

    Environmental and safety factors further separate Cycloheptane from aromatic solvents or light isoparaffins. Lower oral and dermal toxicity, reduced environmental persistence, and gentler vapor pressure figures position it where regulatory compliance becomes a competitive edge. It holds lower solubility for polar and ionic contaminants than linear alkanes, supporting easier downstream separation and less contamination of oil-phase products or polymers.

    Facing Real-World Challenges in Cycloheptane Supply

    As the manufacturer, shipping and storage push us to innovate far beyond standard procedures. Cycloheptane’s flash point sits high enough for safe drum and bulk transport, but still warrants the closed system handling our crews train on each year. We redesign gaskets, seals, and loading docks to account for transient vapor loss. Our experience tells us a clean warehouse and scheduled tank inspections catch leaks before a routine order turns into a regulatory headache. It takes diligence and long-standing familiarity to deliver solvents that won’t pick up residue or moisture during storage transitions.

    Our downstream users work to recycle and recover Cycloheptane wherever possible. From early on, we watched solvent recovery units claim back large fractions from coating lines or extraction equipment. The chemical’s physical stability lets reclamation cycles regenerate product without carrying over much reactant byproduct, which means customers keep waste costs low and environmental reporting simple.

    One persistent issue is the recent tightening in global hydrocarbon feedstock markets. Multi-year planning relies on stable supply of high-purity alicyclics, yet widespread petrochemical volatility caused producers to re-examine everything from sourcing to in-house distillation optimization. Over the last five years, we invested in plant upgrades, redundant supply lines, and real-time analytics to ensure continuity. Our technical development group works directly with upstream partners, ensuring not just volume, but the purity and spec consistency our specialty users require.

    The Human Elements in Cycloheptane Production

    Our operations staff measure, sample, and document every batch because minor temperature drifts, column holdups, and filtration issues show themselves in the final liquid. Commitment to hands-on troubleshooting prevents the appearance of haze, color change, or off-odor that end customers pick up faster than any instrument. Our senior techs take pride in catching problems before they leave our site.

    Training matters. We see new hires grow into reliable operators by shadowing experienced crew who have seen more than one run where a minor deviation led to solvent that the lab would never accept. Each shipment reflects hours of monitoring, not just procedures written down. By fostering this habit of attention, our teams maintain reliability that end-users in research or production quietly depend on.

    Our Approach to Continuous Improvement

    Every shift, we run quality control routines across samples drawn at the still, receiving tank, and final packaging. The work involves real chromatograms, hands-on distillation, and targeted water stripping, not just checkboxes or external inspection reports. When we introduced new in-line sensors for hydrocarbon purity, discrepancies between instrument readings and staff observations triggered process audits until calibration and practice lined up. This vigilance ensures lot-to-lot continuity at levels unseen in commodity solvent supply.

    Over the past decade, customer requests steered us toward tighter specification on sulfur and halide content. Where general trade standards allow for minor traces, our team now eliminates more contaminants up front—testing shows organosulfur below 1 ppm in routine lots. For those preparing high-purity pharmaceutical intermediates or polymers, this difference appears in finished product performance and shelf life. Internal benchmarks drive us to seek cleaner, more stable Cycloheptane each production cycle.

    Supporting End Users Across Industries

    In the lab, Cycloheptane often becomes the solvent of choice for synthetic organic chemistry, extraction, and chromatography. We see demand spikes around pharmaceutical development, resin synthesis, and specialty adhesives. Film-forming behavior differs from linear analogs: faster drying without the steep vapor pressure curves seen with lower boiling isomers. This translates to more controlled application in production, fewer defects, and easier environmental management on site.

    Paints and coatings producers benefit from the solvent’s ring structure, which reinforces gloss persistence and resists fogging in high humidity. Perfume and fragrance formulators call for Cycloheptane due to clean evaporation and negligible scent contribution where other low-boiling alkanes leave trace residues. High-purity lots enter electronics assembly, where washed substrates demand solvent that won’t leave ionics, water, or rings prone to decomposition.

    Feedback from our partners led to container innovations. Stainless steel drums replaced lined barrels to prevent cross-contamination with reactive metals or previous cargoes. We began rinse-validation for all reusable containers and batch-sealed new drums to reduce internal contamination. Our team moved to on-site barcoding and serialized drum management for full traceability, a step driven not by regulation but by the simple need to tell where a sample came from after months in storage.

    Quality Assurance in the Cycloheptane Facility

    We keep an open line with end users through technical support, troubleshooting, and sample tracking. If a customer flags an issue in dissolution rate or haze formation, batch-specific retention samples help us examine what ran differently at the plant. Our commitment to transparency—sharing full chromatographic and spectrometric results—supports customer confidence and helps improve future lots.

    Our control strategy stretches beyond the plant. Partnering with logistics specialists, we track temperature, shock, and seal integrity across every shipment. Temperature- and humidity-monitored trailers arrive at our customers’ warehouses, ensuring delivered product behaves the same as plant discharge. Over seasons, our data showed that variations in transport conditions correlated with rare outlier batches—a finding that let us improve insulation and protection protocols.

    Meeting Safety and Compliance Requirements

    Day to day, we maintain rigorous safety standards for worker protection and environmental responsibility. Employees train on direct handling, spill containment, vapor recovery, and emergency management. Our safety record benefits from this system of mutual accountability, where peers correct each other if a process shortcut risks exposure or contamination. Cycloheptane’s moderate vapor pressure and low acute toxicity allow for safe routine operation—given respect for established handling procedures. Air monitoring and regular leak detection protect both our staff and local surroundings.

    Compliance with international and national regulations underpins our production. Our facility holds both ISO quality management and environment certifications. Material movement across borders meets REACH and TSCA guidelines. Each shipment carries verified documentation for customs and regulatory authorities. We track regulatory trends to anticipate changes in permissible impurity levels or handling standards, so operations adjust early and customer deliveries continue without disruption.

    Looking Forward in Cycloheptane Manufacturing

    As solvent markets grow more demanding, Cycloheptane keeps proving its value by straddling versatility, safety, and reliability. Upstream changes in crude sourcing, process intensification, and tighter emissions targets push us to innovate at every stage. We focus on closed system operations, continuous distillation, and cleaner feedstocks to meet and exceed future purity and consistency expectations.

    Collaboration with universities and technology institutes improves understanding of Cycloheptane’s subtle interactions in advanced formulations. Our R&D labs run pilot-scale co-solvent blends, additive testing, and continuous analytics. As the industries we serve move toward greener, safer chemistry, we see new opportunities to refine the product further—lowering environmental impact, easing recycling, and raising performance for evolving applications.

    Trust grows from decades of experience—turning raw hydrocarbon and hands-on process control into a liquid that quietly sustains industries worldwide. Our approach remains grounded in the daily experience of those who make, test, and deliver Cycloheptane every shift.

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