Acetaldoxime

    • Product Name: Acetaldoxime
    • Alias: Ethanal oxime
    • Einecs: 210-481-2
    • Mininmum Order: 1 g
    • Factroy Site: Yudu County, Ganzhou, Jiangxi, China
    • Price Inquiry: admin@ascent-chem.com
    • Manufacturer: Ascent Petrochem Holdings Co., Limited
    • CONTACT NOW
    Specifications

    HS Code

    917157

    Product Name Acetaldoxime
    Iupac Name N-hydroxyethanimine
    Chemical Formula C2H5NO
    Molar Mass 59.07 g/mol
    Appearance Colorless liquid
    Cas Number 107-29-9
    Melting Point −15 °C
    Boiling Point 82 °C
    Density 0.926 g/cm³
    Solubility In Water Miscible
    Odor Strong, unpleasant
    Flash Point 7 °C (45 °F)
    Refractive Index 1.426
    Pubchem Cid 7891
    Un Number 2332

    As an accredited Acetaldoxime factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Acetaldoxime is packaged in a 500 mL amber glass bottle with a secure screw cap, labeled with hazard and handling information.
    Shipping Acetaldoxime should be shipped in tightly sealed containers, away from sources of heat, sparks, or open flames. It must be stored in a cool, dry, well-ventilated area, separate from strong oxidizing agents and acids. Proper labeling and compliance with all relevant transportation regulations for hazardous chemicals are required during shipping.
    Storage Acetaldoxime should be stored in a cool, dry, well-ventilated area, away from sources of ignition, heat, and incompatible substances such as strong oxidizers and acids. Keep the container tightly closed and properly labeled. Store away from direct sunlight and moisture. Use corrosion-resistant containers, and ensure all storage complies with local regulations for hazardous chemicals.
    Application of Acetaldoxime

    Applications of Acetaldoxime in Industrial Manufacturing

    Acetaldoxime serves as a key intermediary in high-value sectors, supporting diverse synthesis and purification technologies. By integrating our material at controlled stages of your production lines, customers reach strict downstream specifications for specialty products. The following sections provide detailed insights for established downstream processes utilizing our acetaldoxime with compliance, usage parameters, technical steps, and final product output.

    1. Agrochemical Synthesis: Herbicide Formulation Intermediates

    Many global agrochemical groups employ our acetaldoxime in the synthesis of selective herbicides, notably as a precursor for compounds such as Imazethapyr and related imidazolinone-category actives. Producers implement nucleophilic substitution strategies under controlled reaction conditions, maximizing conversion rates and minimizing byproducts. Stringent raw material identification and batch tracking guarantee regulatory traceability and environmental performance throughout active ingredient production.

    Industry compliance standards

    • REACH Registration (EC 1907/2006)
    • US EPA 40 CFR Part 180 (Tolerance Regulation for Pesticide Chemicals in Food)
    • China GB/T 1604-2018 (Pesticide Technical Requirements)
    • ISO 9001:2015 Quality Management for agrochemical intermediates

    Typical usage ratio

    • Typically 0.85–1.1 mole equivalents acetaldoxime per target imidazolinone intermediate
    • Adjustable dosage based on crop selectivity target and downstream impurity profile

    Downstream process integration

    • Introduced post-hydrolysis step to react with substituted aromatic acids
    • Phase-transfer catalysis at 25–45°C for optimal oxime-to-amide conversion

    Final product types

    • Imazethapyr technical
    • Imazapyr intermediates
    • Pre-emergent and post-emergent selective herbicides
    • Custom-blend herbicidal formulations

    2. Pharmaceutical Synthesis: Active Pharmaceutical Ingredient (API) Protection

    Leading pharmaceutical synthesis routes include acetaldoxime as a reversible protecting group for carbonyl functionalities during complex multi-step active ingredient manufacturing. This functional approach secures the desired selectivity in oxime formation before subsequent hydrolysis or conversion under strictly validated conditions. Real-time analytical monitoring supports batch consistency and process safety throughout dedicated cleanroom environments.

    Industry compliance standards

    • US Pharmacopeia (USP) standards for intermediates
    • ICH Q7 Good Manufacturing Practice (GMP) for APIs
    • EU EMA Guideline on Starting Materials (CHMP/QWP/545525/2017)
    • 21 CFR Part 211 (cGMP for Finished Pharmaceuticals)

    Typical usage ratio

    • Stoichiometry: 1.0 mol acetaldoxime per mol of protected carbonyl group
    • Process optimization may lower ratio to ~0.95 mol:1 mol depending on API sensitivity

    Downstream process integration

    • Integrated at the early protection stage during scaffold synthesis
    • Applied pre-purification prior to final deprotection and crystallization

    Final product types

    • Antihypertensive APIs (e.g., captopril intermediates)
    • Nucleoside analog intermediates
    • Custom API scaffolds for contract pharma customers
    • Low-residual pharmaceutical-grade intermediates

    3. Industrial Water Treatment: Oxygen Scavenger Formulation

    Specialized water treatment companies integrate acetaldoxime into oxygen scavenger formulations to prevent oxidizing corrosion in closed-loop cooling and boiler systems. Its fast-acting reactivity offers a safer alternative to hydrazine, especially in applications targeting residual dissolved oxygen. Customer quality teams deploy in-line monitoring to verify dosage and removal performance while maintaining regulatory permitting.

    Industry compliance standards

    • ASTM D1384 (Corrosion Testing Standards for Water Treatment)
    • ISO EN 12953-10 (Water-tube Boilers and Auxiliaries)
    • US EPA NPDES Permit Regulations for wastewater discharge
    • Chinese GB/T 1576-2016 (Water Quality for Industrial Boilers)

    Typical usage ratio

    • 35–60 ppm acetaldoxime per million parts water, adjusted based on feedwater oxygen content
    • Dosage fine-tuned following real-time dissolved oxygen measurements

    Downstream process integration

    • Metered injection into boiler or condenser feedline upstream of reaction zone
    • Combined with other scavengers or neutralizing amines in tailored water treatment blends

    Final product types

    • Oxygen scavenger formulations for power plants
    • Industrial-scale closed circuit inhibitors
    • Pre-mixed boiler water conditioning agents
    • Specialty water quality maintenance products

    4. Organic Chemical Intermediates: Synthesis of Heterocyclic Building Blocks

    Our acetaldoxime activates crucial intermediate steps in the large-scale production of five- and six-membered heterocycles, serving as both nucleophile and nitrogen source in ring-closure reactions. Chemical manufacturers achieve precise control over yield and selectivity by monitoring temperature, solvent polarity, and pH, enabling high-throughput runs at multi-ton scale. In-line analysis verifies conversion rates to finished monomers and custom fine chemicals.

    Industry compliance standards

    • ISO 9001:2015 for chemical production
    • OECD Mutual Acceptance of Data (MAD) for chemical testing
    • Responsible Care Management System (RC14001)
    • REACH compliance for applicable substances (EC 1907/2006)

    Typical usage ratio

    • 0.95–1.2 mol acetaldoxime per mol of targeted heterocycle precursor
    • Ratio adjusted relative to substrate reactivity and side product formation

    Downstream process integration

    • Charge-in at cyclization stage post-alkylation or halogenation
    • Followed by solvent extraction and acid/base workup

    Final product types

    • Pyridine derivatives
    • Oxazoles and related fused-ring monomers
    • Intermediate blocks for solvents, UV absorbers, and photographic chemicals
    • Specialty monomers for polymerization lines
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    Email: admin@ascent-chem.com

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    Certification & Compliance
    More Introduction

    Acetaldoxime: Reliable Chemistry From Core Experience

    Introduction: Shaping Chemical Solutions Through Practice

    Producing fine chemicals starts far before the reaction vessel heats up. In our hands, acetaldoxime has carried its weight for countless customers in both mid-size and volume operations. With every batch, we put our plant reliability and long-running formulation consistency into action, making sure this intermediate fits seamlessly into diverse downstream syntheses. Acetaldoxime, with the formula CH₃CH=NOH, stands as a straightforward but critical reagent that supports several industries, from pesticides to organic intermediates. Decades of working with this molecule have taught us what truly matters: steadiness in composition, safe handling, and cost-effective scale.

    Robust Model: Our Acetaldoxime Offering

    From start to finish, we control each aspect of acetaldoxime production. The model we deliver corresponds to the highest bulk-purity industrial standards—colorless, clear liquid under ambient conditions, and tightly specified water content below 1.0%. Core metrics such as assay (minimum 99% by GC), density, and boiling point align with the demands set by our largest agrochemical customers. We use time-tested processes for precise conversion and purification, ensuring ease of measuring and dosing on customer lines. We put stability and cleanliness above flashy appearances because operational predictability in our client’s plants starts with predictable input.

    Often, procurement teams search for a reagent that performs identically across shipments and batches, minimizing the need for on-site adjustments. That consistent assay profile—achieved by managing our reaction sequence and downstream washing—allows formulators to focus on the next link in their chain, not corrections or impurity tracking. Any unexpected moisture or side products can quickly throw nitrile syntheses or API intermediates off-course, so we take routine batch analysis seriously. Our technical files and sampling access have built a foundation for long-term partnerships.

    Reliable Specifications: Balancing Clarity With Practical Needs

    Instead of boasting about unique features, we have learned, after countless hours troubleshooting in chemical plants, that it is more useful to focus on subtle points that make a direct difference each day. The right acetaldoxime offers fine volatility: not so aggressive as to threaten open-system losses, but still manageable through standard solvent equipment. The flash point remains well above room temperature, simplifying both storage and transfer routines. We supply technical grades appropriate for large-scale syntheses, and our QA teams emphasize clarity on any residual impurities or byproducts. This focus on technical transparency has supported risk assessments for clients in fertilizer intermediates and others manufacturing specialty solvents.

    We never pretend to offer “one size fits all,” because downstream requirements differ sharply between a vinyl resin application and a plant protection intermediate. Some customers need a tight APHA color index range while others prioritize moisture, so batch traceability lets our tech department match the spec to the sector. This custom fit, developed over years of customer feedback rather than theoretical analysis, leads to fewer returns and a faster pace from site delivery to active line.

    Applications Shaped By Actual Performance

    End uses for acetaldoxime start with its role as a versatile intermediate, most famously in the synthesis of aldicarb and other carbamate pesticides. Those working in active ingredient manufacturing rarely have the luxury of adjusting procedures for raw material quirks: batch after batch, they demand a workhorse chemical that reacts cleanly, offers minimal side products, and fits into established waste and utility streams. We have spent time inside those operations, solving issues where a shift in color or residual acetic aldehyde can mean days of downtime. Our product keeps these events rare.

    Water treatment chemical companies also count on acetaldoxime for its preliminary amine conversion steps. Without a strong grasp of potential nitrogenous impurities, trace iron, or color body management, their downstream equipment can see premature fouling or loss of efficiency. So, we work to keep our numbers close to theoretical every time, supporting robust RO, ion exchange, or other downstream treatment processes.

    Synthetic resin producers approach acetaldoxime from a different angle—here, stability under heat matters more, and off-gassing in closed reactors raises unique storage and handling questions. Our experience working alongside client teams during turnarounds and process trials has refined our guidance on tank rotation schedules and real-world shelf life under various temperature conditions. In short, we understand why acetaldoxime is attractive for your route, and we help you sidestep common plant failures.

    Safety, Handling, And Real Risk Mitigation

    Over the years, running and scaling acetaldoxime lines has offered no shortage of lessons in chemical risk management. The compound provides moderate toxicity by inhalation or skin absorption, and its volatility can creep up under summer storage. Clients relying on basic warehouse setups appreciate practical solutions—such as drum material guidance, stack height limitations, and secondary containment layouts—refined by field observation, not desk analysis. We take pride in sharing practices that have prevented headaches: accurate labeling and easy-to-read batch sheets go further than stating “handle with care.”

    Logistics should never be an afterthought. Even a minor packaging leak can spell compliance headaches or regulatory reporting in sensitive jurisdictions. That is why we run secondary QC checks at outbound, tracking everything from seal integrity to MSDS labeling. Where clients operate in tight quarters or need on-site technical support, we send those who have spent years in bulk storage so real-world mitigation advice can actually prevent costly slip-ups.

    Acetaldoxime Versus Other Oxime Compounds

    Working in oxime chemistry, subtle differences separate molecules that look near-identical to the untrained eye. Cyclohexanone oxime forms the core of Nylon-6 chemistry, and methyl ethyl ketoxime appears widely in coatings. Yet acetaldoxime keeps its niche as a nimble intermediate—not too heavy, not too prone to premature hydrolysis, and reacting swiftly under mild conditions. The reason is simple: the smaller methyl group grants it higher reactivity in nucleophilic addition and elimination reactions, while its boiling point and polarity keep it manageable in standard process setups.

    Competitors may try to substitute bulkier oximes or those with slower decomposition rates, but in practice, differences in byproduct profile, reactivity, and separation costs mount up. In the field, we see productivity losses when plants substitute unrelated oximes for cost reasons—yield drops, purification columns foul faster, and overall throughput slides. We get calls from teams scrambling to restore production after these trials, underscoring why it pays to stick with materials with a proven pedigree. Packaging acetaldoxime as simply “another oxime” misses the hard-earned differences found after years of hands-on use.

    Our technical staff, not just office salespeople, has tracked batch performance and impurity drift across hundreds of cycles. The learnings from these records shape how we adjust reaction times, work-up protocols, and long-term shelf stability measures. We have invested in re-tuning our purification steps in response to trends seen over months, not just on lab days. That approach keeps our acetaldoxime offering consistently above what “oxime generics” on the spot market provide.

    How Fieldwork Changes Product Value

    We don’t sell theory. The feedback cycle between those making acetaldoxime and those running real operations makes all the difference for quality. Every year, we revisit batch data and customer KPIs, ironing out even the smallest variation in nitrogen content or trace aldehyde bleed-through. This hands-on iteration minimizes gaps between what a plant tech expects and what they get—no unwelcome surprises, no last-minute workarounds.

    Clients planning to switch a process step often bring our team into early process design, so we troubleshoot as a partner instead of just pushing a barrel. For a pesticide intermediate client, we tailored purification to knock down a stubborn impurity that, while technically within spec, fouled downstream glass-lined reactors. It took weeks of iterative batch sampling and close communication to bring resolution, but it saved them hundreds of labor hours on line cleaning and troubleshooting.

    We have also stepped in where a downstream plant switched to a new filter aid, leading to trace metal contamination and unexpected color shift. Drawing from years of comparative runs, we supplied a different grade with tighter metal specs, then followed up with their team over several runs to ensure long-term stability. Field-based adaptation over templates keeps customer trust high, especially in regulated markets.

    Reputation, Audit, And Documented Quality

    Many long-time buyers now require much more than a certificate—regular audits, on-site visits, and documentation that details change-control history set our process apart from fly-by-night suppliers. Every request for minor spec customization triggers a written record and internal review. We have opened our lines and QA records to external inspectors from multinational corporations and government agencies—sometimes on tight turnaround—because our record supports such scrutiny.

    The real test often comes during unexpected market tightness or price swings. While traders vanish after a problem, we have remained accessible and transparent even during scrutiny after raw material disruptions or energy price spikes. Our product has held its standard during these periods, and if there is ever an unexpected issue, it gets traced, logged, and fixed. Documentation for each lot includes not just the usual COA but trend data to check for batch drift or impurity creep, all shared with customers who wish to dig deep.

    With global customers, it is crucial to align on compliance with hazardous goods rules, customs paperwork, and waste transport documentation. Our staff constantly updates these files to keep customers free from legal exposure. Regulatory compliance counts in global logistics, and up-to-date transport classifications—tested against the latest UN and GHS guidelines—are always available. In many cases, on-site training for new handlers or open calls between our plant and the customer’s safety team have been enough to avoid a mishandled package or an improper unloading.

    Solving Supply Chain And Integration Challenges

    We ship not only a molecule but the assurance that the client’s production will keep moving. In the last few years, raw material bottlenecks, changing customs regimes, and shifting environmental documentation requirements have upended planning for many chemical plants. The product means little if supply is unreliable or batch performance drifts. Advance planning, tight upstream integration, and prompt communication have shielded our partners from costly “line-down” events.

    We have reworked storage and logistics setups to fit customer usage patterns—adjusting drum sizes to fit peculiar warehouse geometry, or pulling forward production to manage seasonal surges without sacrificing quality. It may seem a small step, but predictable truck schedules and live updates are what clients mention when planning multimillion-dollar shut-downs or ramp-ups. Most customers have become more risk-averse over time, so we build redundancy into every layer: two-stage QC on outbound shipments, backup storage locations, and direct lines open for emergency support.

    Challenges In Acetaldoxime Handling And Support Strategies

    Stable acetaldoxime shipments depend on more than clean tanks and clever analytics. Our operations have absorbed the cost of developing special drum linings that cut contamination in summer heat, and shelf-life testing under varied climates has guided our recommendations for safe stowaway in warehouses without air conditioning. Customers shipping material cross-border need assurance on customs hold times and temperature variations; we provide data on how the product fares during long sea or rail transit, helping avoid losses.

    Laboratory analysis can reveal small issues—slight drift in pH, haze development, or slow phase separation—long before these show up as plant problems. We monitor these parameters with every dispatch, updating best-practices for warehouses and end users. Open feedback keeps our suggestions field-driven: for instance, recommending clients use lined pipelines or select compatible gasket materials—steps proven to ward off avoidable downtime.

    Acetaldoxime users often operate in tightly regulated frameworks, viewing small deviations as compliance risks. Our role goes beyond shipping; we supply real answers, connecting customer plant staff directly to operators who have handled the same issues. Instead of canned troubleshooting, we step through process, storage, and even waste protocols, aiming for customer uptime over quick sales.

    Continuous Improvement: Listening To The End User

    Our manufacturing team learns directly from plant experiences, adjusting parameters and even infrastructure in response. Data from continuous process monitoring, logged complaints, and repeated queries guides our product evolution. If trace byproducts shift seasonally due to upstream supply changes, we adapt and test multiple formulations to pin down the best fit. Field failures (even rare ones) trigger review meetings and new batch testing, with documented results shared transparently.

    Several years ago, a customer’s reactor showed scale deposits—AN unforeseen side effect traced to inconsistent trace metal content upstream. Rather than dismissing the issue, our team dug into process histories, found correlations in water source changes, and updated our purification process. Such customer-informed changes forged relationships lasting beyond a transaction, building real-world credibility for both sides.

    We keep a direct line open with technical and procurement staff alike. Formulation shifts, brand launches, or new input source validation always prompt an offer for plant trials or parallel batch shipment on our side. These cycles of learning and adaption allow us to keep delivering value, not just raw product.

    Why Our Acetaldoxime Wins Returning Clients

    The difference between chemical bulk suppliers fades when everyone quotes price, but long-term buyers keep score by supply consistency, hands-on support, and ability to respond fast on the ground. Our acetaldoxime has earned repeat business in some of the most unforgiving sectors—high-volume pesticide intermediates, specialty resins, and challenging treatment chemical applications—because it lines up with what plant engineers need: stable quality, grounded field support, and rapid troubleshooting during an unexpected event.

    Our attention to the full life cycle of acetaldoxime—from raw material, through plant reaction, to client application and waste handling—drives our technical choices and support structure. Not every supplier puts their name behind each lot number; we do, because real accountability and performance tracking through production, logistics, and client integration build trust that untested commodity traders cannot match.

    If you rely on acetaldoxime, you expect more than a chemical in a drum. You deserve a partner steeped in industry practice, willing to back up quality claims with real data and responsive help. That is how we produce and ship this vital intermediate, every single time.

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