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HS Code |
690587 |
| Productname | 5-Chloro-2-Methylaniline |
| Casnumber | 87-63-8 |
| Molecularformula | C7H8ClN |
| Molecularweight | 141.60 |
| Appearance | Light yellow to brown crystalline solid |
| Boilingpoint | 242-243 °C |
| Meltingpoint | 37-39 °C |
| Density | 1.17 g/cm3 |
| Solubility | Slightly soluble in water; soluble in organic solvents |
| Purity | Typically ≥98% |
| Refractiveindex | 1.605 |
| Flashpoint | 110 °C |
| Synonyms | 5-Chloro-o-toluidine, 2-Methyl-5-chloroaniline |
As an accredited 5-Chloro-2-Methylaniline factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | Amber glass bottle containing 100 grams of 5-Chloro-2-Methylaniline, tightly sealed, labeled with hazard symbols and product information. |
| Shipping | 5-Chloro-2-Methylaniline should be shipped in tightly sealed containers, protected from moisture and heat. It must comply with DOT, IATA, or IMDG regulations for hazardous chemicals. Proper labeling, documentation, and use of suitable packaging are required to ensure safety during transport. Handle with appropriate personal protective equipment and in accordance with chemical safety guidelines. |
| Storage | 5-Chloro-2-Methylaniline should be stored in a tightly sealed container, in a cool, dry, and well-ventilated area away from sources of ignition and incompatible materials such as strong oxidizers and acids. Avoid exposure to light and moisture. Ensure proper labeling and keep away from food and beverages. Use appropriate secondary containment to prevent accidental spills or leaks. |
Applications of 5-Chloro-2-Methylaniline in Industrial ManufacturingAs a direct manufacturer of 5-Chloro-2-Methylaniline, we supply this key intermediate into carefully controlled downstream processes across multiple industries. The following application pathways highlight the specific use, compliance requirements, recommended ratios, production integration points, and finished product types for this raw material in real-world industrial scenarios. 1. Agrochemical Active Ingredient Synthesis5-Chloro-2-Methylaniline enters the synthesis of agricultural active compounds such as select herbicides and fungicides based on anilide chemistry. Technical users implement this intermediate in amide coupling or diazotization reactions during the multi-step batch production of active pesticide molecules, where strict traceability and impurity control remain central. Downstream formulation steps refine the actives into commercial crop protection products under plant safety regulations. Industry compliance standards
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2. Pharmaceutical Intermediate for API SynthesisOur product enters pharmaceutical manufacturing as a building block for the synthesis of select drug intermediates, primarily for non-OTC small molecule APIs. Users deploy it in aromatic amination or acylation steps to construct target heterocyclic cores. Regulatory protocols demand full documentation and material traceability from raw material entry through to secondary intermediate isolation, with batch segregation and impurity profile reporting at each step. Industry compliance standards
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3. Colorant and Dye Intermediate Manufacturing5-Chloro-2-Methylaniline serves as a functional raw material for synthesizing industrial dyes, reactive colorants, and pigment intermediates. Dye manufacturers use it in conditions-controlled coupling or condensation reactions to yield highly pure aromatic dye precursors necessary for consistent shade and purity in end-use textiles, printing inks, and plastics coloration. Each batch undergoes tight specification acceptance testing to ensure downstream color fidelity and regulatory compliance in demanding sectors. Industry compliance standards
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4. Specialty Chemical and Polymer Modifier ApplicationsChemical formulators deploy 5-Chloro-2-Methylaniline as a reactive monomer or as an intermediate amine source in the production of specialty resins, crosslinkers, and engineering polymer additives. Users integrate it in tightly controlled polycondensation or grafting steps, often under inert atmosphere, to introduce chloroaromatic or methyl-functional side chains that impact polymer flexibility, heat resistance, or processing profile. Compliance with industrial and food-contact material regulations requires impurity monitoring and residual content analysis in any downstream application that may contact food or packaging. Industry compliance standards
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Working in chemical synthesis for over twenty years has shown us the unique demand for consistency and purity in aromatic amines. Among the many, 5-Chloro-2-Methylaniline stands out because of its specific reactivity, adaptability, and role across key industrial applications. This compound—recognized by its molecular formula C7H8ClN and a relatively low melting point—presents a unique chemical profile. Experienced chemists often select it based on both the electronic effects from the chloro and methyl groups and the way these substitutions influence downstream reactivity.
Refining the process of manufacturing 5-Chloro-2-Methylaniline lets us deliver a product tuned for exacting demands. From reaction stoichiometry to drying and packaging, we focus on minimizing impurities. Even trace contamination can disrupt batch reactions or final product qualification, so every lot is produced under controlled conditions. Our reactors and distillation lines only see this family of substituted anilines, cutting down the risk of cross-contamination. As a manufacturer rooted in the principles of process discipline and continual improvement, we chase the details—monitoring every run with GC and NMR checks so clients in fine chemicals, pharmaceuticals, and dyes start with a product that stands up under pressure.
Reliable suppliers don’t trade on vague claims; they build their reputation on traceability and transparency. Over the years, we refined one main production process for 5-Chloro-2-Methylaniline anchored in selective chlorination and amination techniques. The product emerges as pale yellow to light brown crystals, with a characteristic amine odor that signals proper isolation. Using our standard specification:
Regular customers often ask about heavy metals, color index, and byproduct traces such as 2-methylaniline or 5-chloroaniline. We’ve installed in-line analytics to meet sub-ppm limits where necessary. By investing in rigorous in-process monitoring and final product verification, we provide confidence that what arrives at your plant behaves as documented and doesn’t introduce secondary variables into your process.
Unlike offerings from distributors who blend material from multiple sources, we can pull up batch records showing the synthesis route, origin of raw materials, and stepwise purification. We hold sample reserves from every batch for real-world cross-checking long after shipping, a practice shaped by three decades of working closely with partners in the active pharmaceutical ingredients sector.
Our plant has supplied 5-Chloro-2-Methylaniline to technical directors, chemists, and formulators across several continents. Its primary uses lie in downstream synthesis. In the world of agri-intermediates, the compound often enters as a core structural element for fungicides and herbicides. Medicinal chemistry groups prize it while building substituted quinolines, benzimidazoles, and pyridines—chemical classes where electronic tuning by a chloro and methyl group on the aniline core shape both reactivity and safety profile.
This chemical occupies a nuanced spot: more reactive than unsubstituted anilines, and able to introduce both steric hindrance and subtle electronic effects into the aromatic ring. Using our production method, we regularly achieve impurity profiles that qualify for use in regulated pharmaceutical intermediates. That means fewer distractions at downstream purification and a lower risk of misidentified byproducts.
Long-standing clients in dyes and pigment manufacture highlight the product’s clean boiling and narrow melting range because these qualities feed directly into batch reproducibility. Even after years in production, the feedback from application chemists keeps us adjusting our drying and storage regime. They tell us excess water or trace byproducts can shift yields during diazotization, or muddy the color of specialty azo dyes, so our lines feature active drying columns and sealed transfer. This focus moves from numbers on analysis reports to added value in your vessels, where predictability equals profit.
It helps to put 5-Chloro-2-Methylaniline in context with close relatives. This isn’t a general use amine like aniline itself. The 2-methyl substituent increases steric bulk at the ortho position, influencing how nucleophiles attack and how the molecule handles further substitutions. The 5-chloro delivers a strong electron-withdrawing effect that tempers nucleophilicity, making for more selective transformations downstream. This specialty mix doesn’t appear in standard broad-spectrum applications, unlike less-substituted analogs.
Producers accustomed to older grades or material with less stringent purification can experience surprise after upgrading to a tightly specified lot. End users can push cyclization and substitution reactions with tighter time control, improved yield, and a reduced burden on downstream purification. This difference feels clearest in multi-step syntheses—especially where a small change in starting amine quality cascades through two or three subsequential reactions.
Often, technical teams will try to substitute other chloroaniline isomers or even halogen-methyl combinations. Years of side-by-side plant testing confirm that impurity carryover, handling properties, and final product color can differ sharply. For example, 3-chloro-2-methylaniline will not reproduce the selectivity profiles chemical manufacturers expect from the 5-position isomer. Even the volatility, tendency toward discoloration, and shelf stability shift because of the placement of the substituents.
In direct application, 5-Chloro-2-Methylaniline resists oxidative discoloration better than some para-substituted analogs. For clients in the pigment sector focused on chromaticity, that stability slashes the odds of QA flags at the final step. Our technical sales team has spent untold hours on shop floors across Asia and Europe, calibrating formulation batches and troubleshooting unexpected color drift—which almost always traced back to inferior or unstable starting material.
Volume processors and specialty players both appreciate that knowing the detailed chemistry behind each step matters more than ever. Having survived market swings and regulatory rollouts, we see just how much value comes from institutional memory. For 5-Chloro-2-Methylaniline, even subtle changes in catalyst quality or solvent grade shift not only yield, but impurity profiles. Our engineers and QC leads track process batches in real time, using advanced chromatographic and spectroscopic tools to zero in on byproducts or run deviations before those can compromise end use.
Quality assurance improvements at our facility did not spring up overnight. They followed years of needle-fine adjustments prompted by customer feedback—be it residue in storage drums, uneven melting curves, or suboptimal reaction rates in customer plants. We cut cycle times with on-site microfiltration and switched to new packaging designs based on hands-on field reports. Our own supply chain team manages raw procurement to prevent solvent cross-reaction or shelf-life drop-off, a lesson hard-won from an episode that threatened to compromise several high-stakes shipments.
Chemical regulation also shapes our process. We track and implement all relevant REACH, GHS, and local standards—not as a slogan, but as a competitive imperative. Documentation stays current, MSDS files are actively maintained, and our technical support doesn’t vanish after sales. The reality is, quality and traceability drive customer loyalty far more than pricing games. End users who’ve been tripped up by hidden impurities or variable supply soon realize why a focused, experienced manufacturing approach pays dividends in the lab and on the ledger.
The leap forward in crop protection research, pharma actives, or performance pigments stems from reliable access to high-purity intermediates. 5-Chloro-2-Methylaniline keeps labs and plants moving smoothly because it forms the backbone of synthetic sequences that tolerate little deviation. Graduate students and senior synthetic chemists alike share stories with us about struggling through subpar starting materials, which slowed projects and often led to insufficient or impure final products.
As a result, we channel part of our R&D budget into exploring new production routes and impurity mitigation strategies. A recent innovation at our plant revolves around the use of continuous flow reactions for the initial amination, which squeeze out unwanted side products and cut solvent use per MT by a visible margin. Customers in high-value industries see the benefit: they receive a cleaner product and can push their own reaction pathways further without risk.
Supporting customer research means more than filling an order. It means collaborating on application notes, offering samples for pilot studies, and jointly troubleshooting odd observations in scale-up. Strong manufacturer-customer partnerships move the entire industry ahead, allowing for safer and more profitable developments downstream. Our team has worked directly with pharmaceutical leaders developing new APIs, and also supports smaller specialty firms looking for consistency in dyes and intermediates.
Even with a product as established as 5-Chloro-2-Methylaniline, small tweaks in logistic routines make significant impacts. On request, we supply the product in lined fiber drums, stainless kegs, or moisture-tight sealed bags—depending on customer process needs. Moving from plant to plant, it’s clear that safe, moisture-free storage extends shelf life. Our documentation lays out best practice for ventilation, storage temperature, and segregation from incompatible materials such as strong oxidants.
Plant managers tell us how stray moisture impacts melting characteristics or promotes microcrystal aggregation, so our teams stress the use of desiccants and moisture indicators in every package. Feedback loops from customer QC labs go straight to our production crew, allowing us to refine packaging cycles every season. The result speaks in lower waste, better handling ease, and tighter compliance with each customer’s process documentation.
Supply chains have faced repeated shocks—whether through transport bottlenecks, new regulation, or unexpected quality rejections. We maintain a just-in-time manufacturing approach, backed by local stock reserves at strategic sites. This approach keeps customer plants running and removes the stress that comes from single-source or resold intermediates. The direct connection to our reactors means specification changes or new documentation requests move quickly.
The backbone of modern specialty chemistry depends on building blocks that respond consistently. 5-Chloro-2-Methylaniline keeps earning repeat business because it demonstrates rarely matched predictability at scale. Technical leads across industries notice that not every substituted aniline will behave in the same way through complex, multi-stage synthesis. Our experience, open communication, and willingness to adjust process controls give customers an advantage, from reduced waste to smoother compliance audits.
Every kilogram we ship carries the weight of our team’s attention, process know-how, and decades of field-tested chemical knowledge. Our analytical chemists take pride in each batch certificate, knowing that real-world results—like a pharmaceutical registration or paint color launch—may hinge on the uniformity of a single intermediate. Feedback, even when critical, gets absorbed into the continual process of refining our manufacturing lines.
Shifting consumer regulations, tougher environmental scrutiny, and the rising complexity of end-market applications all demand more than commodity chemical supply. They require confident sourcing from chemical plants who know both the theoretical and practical sides of aromatic amine chemistry. Every step of our process for 5-Chloro-2-Methylaniline reflects this commitment—tracing raw materials from supplier audits, dedicating process hardware, working hand-in-hand with application developers, and adapting to changing global standards.
Decisions in chemical manufacturing ripple across supply chains, product performance, and regulatory compliance. Having a reliable partner for 5-Chloro-2-Methylaniline means more than access to inventory—it means access to expertise and consistency that stand up to the most demanding modern applications.
