Products

4-Nitroso-N,N-Diethylaniline

    • Product Name: 4-Nitroso-N,N-Diethylaniline
    • Alias: N,N-Diethyl-4-nitrosaniline
    • Einecs: 202-164-8
    • Mininmum Order: 1 g
    • Factroy Site: Yudu County, Ganzhou, Jiangxi, China
    • Price Inquiry: admin@ascent-chem.com
    • Manufacturer: Ascent Petrochem Holdings Co., Limited
    • CONTACT NOW
    Specifications

    HS Code

    434891

    Chemical Name 4-Nitroso-N,N-Diethylaniline
    Cas Number 99-59-2
    Molecular Formula C10H14N2O
    Molecular Weight 178.23 g/mol
    Appearance Dark green to black crystalline powder
    Melting Point 75-78°C
    Boiling Point 285°C (estimated)
    Solubility Slightly soluble in water; soluble in organic solvents like ethanol and ether
    Density 1.12 g/cm3
    Synonyms N,N-Diethyl-4-nitrosoaniline
    Pubchem Cid 7468
    Inchi InChI=1S/C10H14N2O/c1-3-12(4-2)9-7-5-8-10(6-9)11-13/h5-8H,3-4H2,1-2H3
    Smiles CCN(C)C1=CC=C(C=C1)N=O
    Uses Intermediate in organic synthesis, dye, and analytical reagent
    Storage Conditions Store in a cool, dry, well-ventilated area

    As an accredited 4-Nitroso-N,N-Diethylaniline factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Amber glass bottle containing 25 grams of 4-Nitroso-N,N-Diethylaniline, labeled with hazard warnings and chemical identification, tightly sealed.
    Shipping 4-Nitroso-N,N-Diethylaniline should be shipped in tightly sealed containers, protected from light and moisture. Package according to regulations for hazardous chemicals, labeling appropriately. Transport by ground or air in compliance with local, national, and international guidelines (such as DOT or IATA), with proper documentation and safety data sheets included.
    Storage 4-Nitroso-N,N-Diethylaniline should be stored in a tightly sealed container, in a cool, dry, and well-ventilated area away from sources of ignition, heat, and direct sunlight. Keep away from incompatible substances such as strong oxidizers and acids. Label containers clearly and store in a secure location, preferably in a chemical storeroom designated for potentially hazardous chemicals.
    Application of 4-Nitroso-N,N-Diethylaniline

    Applications of 4-Nitroso-N,N-Diethylaniline in Industrial Manufacturing

    As an experienced manufacturer of 4-Nitroso-N,N-Diethylaniline, we support specialty production sectors that require this reagent for select synthesis routes and formulation processes. Below, explore practical downstream industrial scenarios where this ingredient plays an essential role, with clear information on industry benchmarks, processing steps, usage ratios, and resulting end-products.

    1. Dyes and Pigments Synthesis for Specialty Colorants

    Leading dye manufacturers utilize 4-Nitroso-N,N-Diethylaniline in the synthesis of azo and nitroso dye intermediates, especially for producing acid, direct, and disperse dyes intended for mature textile and paper markets. The compound acts as a coupling component for nitroso and azo dye formation, impacting shade and fastness properties. Its function in the dye synthesis stage requires precise addition for targeted chromophore production and color consistency.

    Industry compliance standards

    • ISO 105-E04:2013 (Textiles — Tests for colour fastness)
    • OEKO-TEX® Standard 100 (restricted substances in textiles)
    • REACH (EC No 1907/2006, Annex XVII: restrictions related to azo colorants)
    • ZDHC MRSL (Zero Discharge of Hazardous Chemicals — Manufacturing Restricted Substances List)

    Typical usage ratio

    • 0.5–2.0 wt% of total dye precursor batch; ratio varies by chromophore structure and target shade intensity, adjusted during small-scale pilot runs for optimum fastness and color purity.

    Downstream process integration

    • Integrated in the coupling step after diazotization of aromatic amines; controlled metering into the reaction vessel under regulated temperature and pH monitoring. Full conversion checked by thin-layer chromatography and UV-Vis absorbance.

    Final product types

    • Acid dyes for wool & silk industries
    • Direct dyes for cellulosic textiles
    • Disperse dyes for synthetic fibers (polyester, acetate)
    • Pigment intermediates supplied for printing inks

    2. Chemical Analysis Reagents for Laboratory Diagnostics

    Producers of analytical chemistry kits depend on 4-Nitroso-N,N-Diethylaniline as a specialized chromogenic reagent for sensitive quantitative determination of various analytes, such as nitrite ions and iron complexes, in water and environmental testing kits. Its selectivity and rapid color development under standard assay conditions support precise laboratory and field diagnostics where trace detection is critical.

    Industry compliance standards

    • ISO 3696:1987 (Water for analytical laboratory use)
    • EPA Method 354.1 (Nitrite in water by colorimetry)
    • EN ISO 11732 (Water quality — Determination of ammonium, nitrite, and nitrate)
    • GLP (Good Laboratory Practice) system requirements

    Typical usage ratio

    • 0.05–0.2 mg per test sample; adjusted based on expected analyte concentration and optical path length, as validated by kit calibration curves.

    Downstream process integration

    • Added in the detection module of reagent kits. Blended in dry or liquid format with stabilizers. Reactivity stabilized by packing under inert conditions, with QA batches verified for response factor and baseline shift.

    Final product types

    • Nitrite test strips and colorimetric assay kits
    • Iron determination reagent solutions
    • Water quality monitoring field kits
    • Photometric analysis reagents for environmental laboratories

    3. Pharmaceuticals API Intermediate Synthesis

    Several pharmaceutical plants employ 4-Nitroso-N,N-Diethylaniline as a key starting material for the synthesis of specialty active pharmaceutical ingredient (API) intermediates, particularly those involving nitroso derivatives which form part of more complex molecular scaffolds. Its purity and consistent reactivity support stringent API batch-to-batch reproducibility and ensure downstream synthetic integrity for global markets.

    Industry compliance standards

    • ICH Q7 (Good Manufacturing Practice Guide for Active Pharmaceutical Ingredients)
    • USP/NF & EP monographs (as applicable for APIs/intermediates)
    • 21 CFR Part 211 (FDA current Good Manufacturing Practices for finished pharmaceuticals)
    • ISO 9001:2015 (Quality Management System for pharmaceutical raw inputs)

    Typical usage ratio

    • 1.5–3.0 mol percent relative to core substrate; exact ratio defined by route selection, yield optimization, and impurity control during preclinical route scouting phases.

    Downstream process integration

    • Introduced at the early stage of API intermediate synthesis, usually by direct alkylation or nitroso coupling followed by downstream transformations. Materials tracked by lot throughout the process; reactivity confirmed via HPLC.

    Final product types

    • Pharmaceutical API intermediates for cardiovascular drugs
    • Complex aromatic intermediates in anticancer R&D
    • Nitroso-derived building blocks for generic drug substances
    • Fine chemical blocks used in clinical trial supply

    4. Specialty Rubber and Polymer Antioxidants

    In the production of specialty rubbers and selected industrial polymers, 4-Nitroso-N,N-Diethylaniline enters formulations as a custom antioxidant precursor. Its role as a stabilizer during polymerization improves heat- and oxidation-resistance in end-use elastomers, especially where UV or thermal stress threatens polymer longevity. Process engineers prefer its predictable reactivity during the compounding phase, supporting finished part performance under demanding service conditions.

    Industry compliance standards

    • ASTM D2000 (Standard Classification System for Rubber Products)
    • ISO 9001:2015 (Process and quality control certification)
    • REACH pre-registration and notification as required for polymer use
    • UL Yellow Card (Product safety for plastic materials, as applicable)

    Typical usage ratio

    • 0.1–0.6 phr (parts per hundred rubber by weight); final inclusion determined by stress test protocols, thermogravimetric data, and target polymer matrix.

    Downstream process integration

    • Mixed during elastomer compounding alongside other stabilizers, before vulcanization or extrusion. Dispersed using internal mixers to ensure uniform activity and effectiveness, monitored by accelerated aging tests.

    Final product types

    • Automotive seal and gasket materials
    • Heat-resistant technical rubber parts
    • Industrial belts and hoses with enhanced oxidative stability
    • Polymer sheets for outdoor equipment applications
    Free Quote

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    Certification & Compliance
    More Introduction

    4-Nitroso-N,N-Diethylaniline: Our Core Intermediate Powering Modern Chemistry

    Practical Insights from our Production Floor

    As a chemical manufacturer with a long history navigating the world of aromatic intermediates, we’ve dedicated years optimizing the synthesis and purification of 4-Nitroso-N,N-Diethylaniline. Chemists in our facilities know this compound by its green-to-brown crystalline appearance and characteristic odor, ingrained from daily interactions during every batch. Production staff understand the changes in crystal morphology that come with adjustments in temperature or solvent, so every kilogram reflects a certain depth of craft as well as raw science.

    Our process starts from well-tested starting materials and we monitor every stage, from diazotization through to nitrosation, to avoid unwanted by-products. Specifying a guaranteed purity over 98% for our 4-Nitroso-N,N-Diethylaniline, we let users trust the integrity of each shipment, batch after batch. Our R&D team constantly looks for ways to further minimize trace amines or acidic residues which can complicate end uses. Chemists in our plant spend most of their time analyzing not just product quality, but how these traces might influence downstream product performance—especially when the compound moves towards producing colorants or advanced analytical reagents.

    Applications: Color Science, Analytical Chemistry, and More

    4-Nitroso-N,N-Diethylaniline has carved out a unique niche in dye chemistry and analytical labwork. Its main value lies in forming intensely colored azo dyes. Dye makers prize the nitroso group, which reacts efficiently with coupling partners and enables the creation of orange and red dye shades. Compared with traditional aniline and diethylaniline, adding the nitroso group transforms both reactivity and end-color.

    In our daily manufacturing life, we hear customer feedback from small-batch textile dye houses and bulk pigment operations alike: they note the consistency of reaction yield and brightness of color from our product. Years of tuning process parameters—pH, reaction time, concentration—translates to a pigment builder that behaves reliably, avoiding unexplained batch-to-batch drift. Dye engineers report fewer filtration issues and less variability in spectral readings. For those focusing on fabric or synthetic polymer coloration, our technical team keeps track of how impurities (even below 1%) lead to muddiness or unwanted off-hues, so we invest in deeper refinement.

    Moving beyond dyes, lab-based analytical chemists use 4-Nitroso-N,N-Diethylaniline as a reagent for identifying or quantifying trace metals, especially in environmental or clinical contexts. For instance, detection kits for trace nitrite or aromatic amines often rely on color changes triggered by this intermediate. We regularly consult with instrument makers and assay designers; over the years, we’ve found that purity here affects not just background signal but time to endpoint and color sharpness during detection. Our hands-on involvement lets us troubleshoot with partners when unusual baseline drift appears, ensuring their readings remain trustworthy.

    Some customers grow into high-purity applications, such as photometric analysis where stability and low noise are crucial. Here, we push even tighter control over moisture content and inorganic ions, offering material with specifications tailored for instrumental assays.

    Key Differences: What Sets Our 4-Nitroso-N,N-Diethylaniline Apart

    Working as an actual producer, we see a constant stream of samples from around the globe. Side-by-side testing shows consistent gaps between batches from resellers and direct-from-source material. Many third-party batches come with variability in both hue and odor—a sign of uncontrolled by-products or storage degradation. On the shop floor, our teams invest heavily in both continuous flow and batch quality review, hunting down unexpected secondary amines or residual acidic species. We run both qualitative spot tests and modern chromatographic profiling so every drum we dispatch is right at standard.

    Over time, we’ve also learned that some customers need special physical forms. While standard crystalline powder suits most dye producers, pharmaceutical labs may request fine-milled grades for quicker dissolution. Some applications perform better when delivered granulated, especially for automated dispensing or dust control. In these cases, we design custom finishing steps—screening, jet-milling or controlled recrystallization—rather than simply repacking.

    One new area where we’ve stepped up process controls is in photochemical purity. Certain advanced uses—fluorescent dye preparation, sensitive analytical systems—demand reduced light-absorbing impurities. Our team addressed this by refining washing protocols and introducing additional recrystallization cycles. The result is a product that performs in low-tolerance, high-precision environments, without operators seeing the unpredictable interference reported from generic material.

    Product Model, Physical Qualities, and Handling Insights

    Our typical model features a well-defined batch system; every order comes with a lot number, tied directly to retained samples and batch records. Technical staff maintain full spectra and comparative data for dispute resolution or continuous improvement. Each batch of 4-Nitroso-N,N-Diethylaniline keeps to a melting point range around 70 to 74°C, with a slightly green or brown crystalline appearance. The faintly aromatic odor, often noticed in process air, signals correct composition and low impurity—too strong a smell usually points to contamination or by-product formation, so we reject such product early.

    Transport and storage recommendations come from hard-earned experience gained watching batches degrade under high humidity or sunlight. Ideal storage involves tightly sealed containers, dry ambient conditions, and avoidance of direct UV. Process operators know even moderate exposure will slowly dull the vibrant color, so they move fast between dispatch and use, minimizing unnecessary handling.

    In our plants, workers always don protective handling gear due to the compound’s reactivity and sensitivity. Industrial practice puts a premium on keeping product dust to a minimum; even small escapements can trigger both health checks and rework. As a manufacturer, we learned the cost of small leaks or packaging tears in both material loss and operator downtime.

    Why We Treat Analytical Data as Vital

    Operating high-volume lines, we’ve seen first-hand how subtle process drifts—such as a 0.5°C change in cooling or a slight solvent impurity—leave fingerprints in the final product. Our QC laboratory maintains not just standard titration and TLC checks but also invests in advanced HPLC and GC-MS analysis, building a reference library across seasons and years. This long-term database helps us quickly spot problems if a customer reports solubility change, unexpected color, or reactivity drift. This kind of feedback loop from manufacturing to lab to end user closes the distance between the plant and the real workbench.

    Comparing historical runs, we sometimes detect shifts in trace impurity patterns that correspond to small upstream supply changes—such as new batch sources for diethylaniline, or alternate nitrosating agents. Our lab then advises process engineers on minute adjustments, supporting the goal of reproducibility for every user, whether running textile vats or spectrophotometric assays.

    Customer Experience, Problem Solving, and Continuous Improvement

    Direct relationships with end users change how we view improvement. Each feedback call or sample return teaches us where standard QC misses something laboratory research notices. If a customer runs into inconsistent coupling efficiency or slight haze in their finished dye, our technical team will run side-by-side comparative tests with retained reference samples. Sometimes we’ll re-treat or reprocess returned batches, feeding lessons back into our mainline process.

    We’ve also responded to customer needs regarding sustainability and safety. Our engineering staff collaborated with downstream partners in textile and pigment production to minimize solvent residues, recover heat in the reaction stage, and explore alternative reagents that cut overall waste. Several times, changes in regulatory limits prompted us to review phasing out hazardous minor reagents, switching to greener solvents or improving venting and recovery. These steps improve both end user safety and downstream environmental compliance, providing credibility for customers dealing with audits or new compliance targets.

    Dye makers with a focus on high-intensity color or demanding print stability come to us with performance-based complaints. We trace these back to microscopic differences—particle size, residual acidity, or trace ions—handling each with process tweaks, tighter packaging, or after-sales support. We see this hands-on troubleshooting as the defining difference of our role as a manufacturer.

    Market Trends, Innovation, and Future Developments

    What we’ve noticed from decades inside the industry is a slow but steady demand shift: once, most of our 4-Nitroso-N,N-Diethylaniline flowed into large dye houses concerned only with volume and price. Now, precision markets—specialty pigments, sensor manufacturers, analytical labs—push us for higher transparency in batch data, lower impurity profiles, and closer collaboration. Our laboratory upgrades once focused solely on throughput; today, they support new customer explorations, such as tuning the product for light stability or optimal response curves in colorimetric assays.

    Research collaborations increasingly drive product evolution. We work with university groups probing for new detection approaches or engineers experimenting with high-speed textile jets. Their reports guide us to tweak crystal form or purity, test for rare contaminants, or even develop custom packaging.

    End users now ask more about traceability, regulatory documentation, and sustainability. To address these, our documentation system evolved to include deeper batch-level transparency, full regulatory compliance records, and the ability to track each pail of product back to raw material sources. We share not only certificates of analysis but also ongoing trends in QC data so customers can see the full quality chain.

    We’ve invested in process automation, real-time data capture, and new water purification systems to both stabilize batch-to-batch quality and keep waste below tightening limits. Operators receive ongoing training in green chemistry and energy conservation, ensuring that enhancements are built in from ground level through to dispatch.

    Differences from Other Market Offerings

    Our vantage point as manufacturer gives a unique angle compared to resellers or brokers. The key difference is control. Every parameter, from starting material sourcing to reaction workup, stays under our oversight. We do not depend on inconsistent supply streams, unknown intermediaries, or bulk blending practices typical of some lower-cost market options. The result is a reliability not found with non-manufacturer brands.

    Product support is immediate; questions on batch behavior reach our factory chemists, not a customer service rep reading a spec sheet. When purchasers face a unique processing step, they can speak directly to our engineers—sometimes even sending process samples for joint evaluation and troubleshooting.

    We deliver only product which our in-house teams have physically handled, checked, and signed off based on years of production knowledge. Customers gain not just a spec sheet, but a partner who can help adjust methods or design new testing protocols if an unexpected result surfaces.

    For larger buyers who track environmental impacts, direct purchase from an origin producer streamlines compliance checks. We provide manufacturing records, supply chain transparency, and compliance guarantees unavailable from brokers or distributors. Reaching back through our process, we can confirm or demonstrate how each batch meets evolving standards on contaminants or banned substances.

    On a technical level, our 4-Nitroso-N,N-Diethylaniline reaches a higher standard for physical profile: absence of trace solvent, strict crystalline morphology, and consistent melting range. Bulk shipments retain the same qualities as laboratory jars; we avoid secondary blending or repacking, a common shortcut that may introduce new contaminants.

    Lessons from Decades in the Industry

    Having made, analyzed, and shipped this compound for years, we recognize that its real-world value only becomes clear in the hands of those using it every day. Every improvement in synthesis, packaging, and documentation springs from honest feedback—sometimes praise, often critical detail—direct from users. We remember specific cases: a textile engineer noticing better washfastness, a spectroscopist discovering lower noise in their calibration runs, or an environmental lab identifying less baseline drift in pollution screening. These are results that matter, shaping how we approach every production run.

    Scaling up also brings challenges. Large-batch production risks persistent heat gradients, local pH pockets, and mechanical stress—each a potential cause of off-spec product. We respond by intensifying process monitoring and creating robust protocols for temperature, mixing, and purge cycles. Our teams rotate across production and laboratory roles so they can spot issues early, growing multi-skilled operators who understand both the chemistry and real-world performance that customers expect.

    New markets keep opening for this chemical—precision electronics, medical diagnostics, specialty coatings. Their demands drive us to rethink old habits, accelerate analytical control, and develop variations suited for new technical hurdles. It’s a reminder that every so-called “routine” batch forms the foundation for further discovery, provided the chemistry delivers the expected results.

    Summary: Our Commitment to Practical, Reliable Chemistry

    For us, 4-Nitroso-N,N-Diethylaniline represents more than a commodity. It brings together skills in organic process chemistry, careful analysis, regulatory compliance, and customer collaboration. Whether you operate a textile mill, design analytical assays, or explore new pigment formulations, our experience as a trusted, ground-level producer ensures each shipment meets the needs of the real world—not just paper targets.

    Our promise remains simple: know your source, communicate results directly, and never stop learning from the field. Every batch carries the hands-on legacy and constant innovation of a team committed to transparent, high-quality manufacturing.

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