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HS Code |
272750 |
| Chemical Name | 4-Nitro-N,N-Dimethylaniline |
| Molecular Formula | C8H10N2O2 |
| Molecular Weight | 166.18 |
| Cas Number | 100-23-2 |
| Appearance | Yellow crystalline solid |
| Melting Point | 74-76°C |
| Boiling Point | 161-163°C at 14 mmHg |
| Density | 1.20 g/cm3 |
| Solubility In Water | Slightly soluble |
| Flash Point | 155°C |
| Purity | Typically ≥98% |
| Synonyms | p-Nitro-N,N-dimethylaniline |
| Smiles | CC1=CC=C(C=C1)[N+](=O)[O-] |
| Inchi | InChI=1S/C8H10N2O2/c1-10(2)8-5-3-7(9(11)12)4-6-8/h3-6H,1-2H3 |
As an accredited 4-Nitro-N,N-Dimethylaniline factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 250g of 4-Nitro-N,N-Dimethylaniline is supplied in a sealed amber glass bottle, labeled with hazard warnings and safety instructions. |
| Shipping | **Shipping Description for 4-Nitro-N,N-Dimethylaniline:** Ships as a solid in tightly sealed containers, protected from light and moisture. Label as a hazardous chemical: toxic, harmful by inhalation, ingestion, or skin contact. Follow all applicable regulations for transport (DOT, IATA, IMDG). Store and ship with compatible chemicals only, avoiding oxidizers and strong acids. |
| Storage | 4-Nitro-N,N-Dimethylaniline should be stored in a tightly closed container, in a cool, dry, and well-ventilated area away from sources of ignition and incompatible substances such as strong oxidizers and acids. Keep it protected from light and moisture. Properly label the storage container and ensure access is restricted to trained personnel, following all relevant safety protocols and regulations. |
Applications of 4-Nitro-N,N-Dimethylaniline in Industrial Manufacturing4-Nitro-N,N-Dimethylaniline serves as a targeted intermediate in chemical synthesis, supporting several key downstream industries. As the direct producer, we supply this material for advanced processes where chemical purity and controlled performance are critical. Below, we detail its main industrial application fields, including technical compliance, process-fit, and final transformations. 1. Azo Dye Intermediates for Textile PigmentsLeading dye manufacturers incorporate 4-Nitro-N,N-Dimethylaniline as a core intermediate to yield high-purity azo dyes, particularly in the synthesis of disperse, acid, and solvent dyes. The nitroaniline structure enables controlled diazotization and subsequent coupling steps, determining the final shade, lightfastness, and compatibility with polyester and acetate fabrics. The batch process must respect specific reaction time and temperature for reproducible tone and yield. Industry compliance standards
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2. Photographic Chemical ManufacturingPhotographic industries use 4-Nitro-N,N-Dimethylaniline for synthesizing photographic color developers and stabilizers. Its specific structure is integral to coupling agents and color-forming intermediates, impacting color definition and development rate. Production of color photographic paper and film emulsions relies on well-defined purity and reactivity, with precise documentation as per imaging industry regulations. Industry compliance standards
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3. API Synthesis for Antimalarial IntermediatesChemical and pharmaceutical manufacturers use 4-Nitro-N,N-Dimethylaniline as an important precursor in multi-step syntheses of select antimalarial drugs. Its introduction at an early stage provides the necessary electron-withdrawing group that advances further transformation to final API forms like aminoquinoline analogs. Purity and trace contaminants are tightly monitored against cGMP and pharmacopeia specifications. Industry compliance standards
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4. Rubber Chemical SynthesisSpecialty rubber chemical producers and compounding agents utilize 4-Nitro-N,N-Dimethylaniline as a vital precursor in accelerator and antioxidant manufacturing chains. This material allows precise introduction of nitro-functionality, required for downstream condensation and cyclization that control rubber curing performance, final product life, and heat resistance in industrial rubber goods. Industry compliance standards
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5. Chemical Analytical ReagentsIn analytical laboratories and fine chemical plants, 4-Nitro-N,N-Dimethylaniline acts as a colorimetric reagent to determine trace metal ions and nitrite levels. Laboratories require exceptionally clean material to reduce blank values and achieve reliable, traceable detection. The compound’s reactivity allows for direct coupling or reduction reactions, forming chromophoric complexes for visible detection and quantitative analysis. Industry compliance standards
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6. Organic Pigment SynthesisPigment producers apply 4-Nitro-N,N-Dimethylaniline in the manufacturing of select yellow and orange organic pigments. The nitro-dimethylaniline nucleus reacts with other aromatic components to generate stable pigment molecules offering high tinting strength, dispersibility, and resistance to solvents and UV. Manufacturing requires close monitoring of reaction completeness, impurity removal, and shade matching by strict in-process QC. Industry compliance standards
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Competitive 4-Nitro-N,N-Dimethylaniline prices that fit your budget—flexible terms and customized quotes for every order.
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As chemical manufacturers with decades of experience refining the craft of meaningful synthesis, we pay close attention to the needs of those who depend on the consistent quality of intermediates like 4-Nitro-N,N-Dimethylaniline. Our daily work touches dyes, pharmaceuticals, and specialty chemical end markets. We handle thousands of metric tons each year, but no product has quite the same combination of reactivity, stability, and process flexibility as this one.
Walk into any production hall where dye intermediates pass from one reactor to the next, and you’ll spot two things: the technical know-how required to synthesize clean, pure batches, and the unique role this compound plays in transferring chemical energy in the right direction. It’s the nitro group at the para-position of the aromatic ring, surrounded by two methyl groups on the amine, that yields a molecule both electron-rich and ready to participate in targeted substitutions or reductions. The balance matters: shift those groups elsewhere, and you alter both color properties and downstream reactivity.
For users with demanding quality standards, our 4-Nitro-N,N-Dimethylaniline comes with a purity that regularly exceeds 99%. Years spent tightening distillation and crystallization steps mean our material rarely carries more than a trace of byproduct—this reduces waste and process complexity for our customers. Moisture content sits at industry-leading lows, because we’ve invested time in refining drying and storage methods—customers now report less agglomeration and better shelf-life. Every batch we prepare leaves the plant with a certificate tying it back to our analytical work, using HPLC, GC, and NMR, not just visual checks.
The technical parameters matter less as standalone numbers and more in how they translate to reliable performance, scalable production, and fewer headaches for plant operators. Take melting point: our batches consistently fall between 65°C and 68°C. Outside of that, processing troubles show up: uneven feed, sticky conveyors, blocked pipes. Collateral impact on throughput and downtime prompts us to keep the range tight, batch after batch.
Color is another measure. In textile dye manufacture or organic synthesis, a hint of yellow over the usual pale color signals heavy metal residues or precursor leftover—a risk for both reactivity and final product purity. Our in-process controls filter out those chances, so you get a raw material that finishes reactions clean. The same story shows up in residue after ignition, usually held below 0.1% in our plant, where routine checks identify trouble before it leaves the sphere of our quality team.
Occupying a middle ground between commodity chemicals and custom fine chemicals, 4-Nitro-N,N-Dimethylaniline is best known as a core raw material for azo and methine dyes. Over the decades, our teams have seen shifts in demand—from classic textiles to specialties like ink-jet colorants and digital printing. As color standards evolve, our process flexibility keeps pace, with every lot designed to meet newer color fastness requirements or fit more demanding purity constraints.
In pharmaceuticals, researchers count on the stable electron-donating and accepting features of this molecule. Whether as a precursor for analgesic components, or in synthesizing intermediates for anti-bacterial agents, our compound’s well-defined purity and reaction profile allow for scale-up from lab to multi-ton production. Years of partnership with pharma innovators have proven that cleaner raw materials mean fewer surprises in downstream synthetic routes and faster regulatory compliance.
Specialty chemical makers use it as a coupling agent or intermediate in photoinitiator synthesis or fluorescence-labeling chemicals. Every time a new application reaches us, we look for two things: special impurity constraints and shipment format. Whether a research grade or a 20-metric-ton shipment in dedicated tank trucks, we have created protocols for traceability, contamination avoidance, and packaging safety—because in scale-up, a failed batch means expensive delays and wasted resources.
There is no shortcut around robust process controls. Even minor fluctuations in raw nitrobenzene input quality, amine methylation efficiency, or even steam quality can produce off-grade product. Early in our manufacturing journey, we learned to control every step, from the first reaction in nitration vessels to the final melt crystallization. Years of fine-tuning let us hold to consistent specifications, not just book values. Our operators, many of whom have spent their working lives in these halls, know how to spot upstream signals for downstream yield or purity trouble.
Our manufacturing footprint gives us resilience against raw material price swings and logistics hiccups. Owning the upstream and downstream integration means we can buffer our customers from shocks in global benzene or nitric acid markets. We routinely analyze market and logistics trends to pre-empt supply disruptions, and our multilingual logistics staff keep batches moving to all continents. Many customers choose us not just for cost, but because interrupted shipments of intermediates wreak havoc on finely-tuned production schedules.
Manufacturing 4-Nitro-N,N-Dimethylaniline carries responsibility beyond simple compliance. As chemical producers, we recognize our duty in continuously improving site safety and operational transparency. Each month our EH&S staff update risk assessments using the latest learnings from global regulatory developments. We maintain closed handling systems with advanced containment and real-time monitoring, and routinely invest in scrubbing and wastewater treatment upgrades. Sustainable production goals draw on years of incremental improvements: less waste solvent per ton, reduced process water demand, and stricter emissions controls.
Customers, especially those in the EU, North America, South Korea, and Japan, set higher bars for chemical lifecycle assessments, and expect effective systems to track every batch’s carbon and regulatory footprint. Our traceability systems support this with detailed logs from raw material intake through production, storage, and dispatch. Data points link back to on-site audits by international certifiers—these outside reviews of our operational records, product sample archives, and waste records ensure we stay ahead of regulatory trends.
Newer environmental regulations require forward thinking. By partnering with waste management firms and investing in process redesign, trace nitrosamines and nitroaromatic byproducts no longer present the risk they once did. Still, trace amounts can slip past even the best systems, which is why routine third-party independent testing backs up our own lab data. Meeting our obligations to both local communities and our customers means transparency is our best tool: clear reports, shared learnings, and full disclosure of risks.
Many customers ask, why pick 4-Nitro-N,N-Dimethylaniline instead of one of the dozens of close analogs? Structurally, the para-nitro group maintains a delicate electron distribution across the aromatic ring, while the two methyl groups boost the compound’s lipophilicity and solubility in both organic solvents and nonpolar matrices. Other positional isomers or secondary nitro-anilines tend to introduce steric hindrance or leave open sites for unwanted side reactions.
Compare it to unsubstituted nitroanilines: they often show greater reactivity toward nucleophilic substitution but produce broader impurity profiles during downstream synthesis. Or look at N,N-dialkylanilines without the nitro group; they lack the requisite electron-attracting nature for most dye-coupling reactions, and produce paler or fading shades when processed into colorants. The specific substitution pattern in 4-Nitro-N,N-Dimethylaniline enables both more vibrant dye colors and controlled reactivity—something time-tested and non-negotiable for large-scale dye makers.
We have customers who once tried alternatives—o-nitro or m-nitro isomers, nitroanilines with ethyl or bulkier alkyl groups—but returned because finished products lacked stability, or plant systems required costly modifications. Subtleties in melting point can lead to processing issues; mismatched polarity or solubility throws off yields, or finished product shelf life. Reliability in end-use performance traces back to consistent substitutions, crystallinity, particle size, and impurity control—all painstakingly dialed in over years of accumulated expertise.
Customers remind us that their reputations can hang on the small details. In one instance, a major Asian dye manufacturer flagged a batch due to trace impurities, undetectable with standard TLC but evident in field performance: dye fading after repeated washing. Our corrective action, including retooling in-line GC checks and investing in purer nitration inputs, directly improved their lot yields and deepened partnership trust.
A pharmaceutical client scaling up an analgesic intermediate gave us specific purity targets, requiring retrofitting of ancillary purification vessels and higher-precision heating controls. Achieving less than 0.02% certain nitrosamines demanded months of sustained process review and operator retraining. This case confirmed our view that nothing beats direct collaboration and data-sharing; standard specs only tell part of the story.
Our supply chain partners report that precisely specified packaging, backed by multi-barrier linings and real-time temperature tracking during sea crossings, led to a marked decrease in clumping or batch spoilage in difficult climates. Not every exporter takes stability and handling as seriously—which is why customers often visit our facilities for joint risk reviews and process walk-throughs. Openness breeds continuous improvement.
Producing consistently high-purity 4-Nitro-N,N-Dimethylaniline brings both predictable and unique hurdles. Weather swings can alter condenser output and energy requirements, requiring adaptive controls and alert operators. Raw material fluctuations—whether in supply volatility or unexpected minor contaminants—demand verified procurement channels and real-time analytical support. Our decade-long commitment to in-process automation serves us well, but every piece of gear, from centrifuges to dryers, receives regular upgrades to catch problems before they affect output.
Waste minimization remains a challenge. Even with improved solvent recycling, some process stages generate persistent byproducts, not all of which are simple to treat or reuse. Industry partnerships, process modeling, and outside R&D funding have all contributed solutions: new catalysts, alternative feedstocks, and membrane-based purification come from continuous trial and error. As process engineers, we know that incremental gains compound year over year—every percent more yield, every kilogram less waste tips scales for both profitability and sustainability.
We see the future shaped not simply by price competition, but by the ability to navigate tightening regulatory rules, sharper end-user performance requirements, and a heightened social focus on transparency. Our young chemists and veteran operators alike bring practical ingenuity to the table, from devising quicker in-process tests, to designing closed-loop solvent handling, or fine-tuning granulation and drying cycles for better performance in humid climates. We make our wins by relentless critical review and open-minded learning from customer and regulator feedback.
Standing in our production facilities, it’s easy to recognize that no brochure or spec sheet can match the insights earned from daily batch reviews, midnight maintenance repairs, or cross-border troubleshooting calls with partners around the world. 4-Nitro-N,N-Dimethylaniline may never be a household name, yet the products and services powered by its reliable chemistry touch millions—from brilliantly colored textiles, to essential medicines, to future-facing specialty materials. Every day, we take the lessons of the past and the drive to improve into every kilo, drum, and container that bears our name.
