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HS Code |
337885 |
| Cas Number | 104-85-8 |
| Molecular Formula | C8H7N |
| Molar Mass | 117.15 g/mol |
| Iupac Name | 4-Methylbenzonitrile |
| Appearance | Colorless to pale yellow liquid |
| Boiling Point | 232-234 °C |
| Melting Point | 16-18 °C |
| Density | 1.003 g/cm3 |
| Solubility In Water | Slightly soluble |
| Flash Point | 96 °C |
| Smiles | CC1=CC=C(C=C1)C#N |
| Refractive Index | 1.524 |
As an accredited 4-Methylbenzonitrile factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | The 4-Methylbenzonitrile is packaged in a 250 g amber glass bottle, labeled with hazard warnings, product details, and safety instructions. |
| Shipping | 4-Methylbenzonitrile is typically shipped in tightly sealed containers, compliant with international regulations for hazardous chemicals. It should be kept away from heat, sparks, and open flames during transport. The shipment must be clearly labeled, and handled by trained personnel wearing appropriate protective equipment to ensure safety and prevent leaks or contamination. |
| Storage | 4-Methylbenzonitrile should be stored in a tightly closed container in a cool, dry, and well-ventilated area, away from sources of ignition and incompatible substances such as strong oxidizers and acids. Keep the chemical away from direct sunlight and moisture. Proper labeling and secure storage help prevent accidental exposure or spills. Always refer to the SDS for full handling and storage guidelines. |
Applications of 4-Methylbenzonitrile in Industrial ManufacturingAs an established producer of 4-Methylbenzonitrile, we supply this fine chemical intermediate to global manufacturers operating in tightly regulated supply chains. The following application scenarios demonstrate real, downstream industrial uses, each shaped by compliance obligations, process requirements, and formulation practicalities encountered at scale. 1. Pharmaceutical Intermediate for Anti-Hypertensive Compounds4-Methylbenzonitrile serves as a specific building block in the synthesis of several aromatic pharmaceutical intermediates, especially those directed at cardiovascular therapies. Chemical manufacturers incorporate this substance in controlled condensation and amidation steps, transforming it into key intermediates en route to finished drug substances under stringent traceability and batch documentation regimes. Industry compliance standards
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2. Agrochemical Synthesis for Active Ingredient ProductionWithin the agrochemical sector, downstream formulators leverage 4-Methylbenzonitrile as a nitrile precursor in the production of benzyl-containing herbicides and fungicidal compounds. The material’s purity and traceability affect the efficacy and regulatory status of end-use crop protection agents, requiring validation against strict quality protocols from procurement through to packaging. Industry compliance standards
Typical usage ratio
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3. Dye and Pigment Intermediate in Organic SynthesisLeading dye and pigment producers incorporate this raw material as a tailored aromatic nitrile in the manufacture of specialty colorants. Its introduction determines chromatic properties in downstream azo and anthraquinone pigments, arising from nucleophilic aromatic substitution and diazotization steps where batch color consistency and trace impurity controls affect end-user performance in coatings and plastics. Industry compliance standards
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4. Specialty Chemical Intermediate for Liquid Crystal Material ManufacturingProducers of advanced display materials utilize this compound in the customized synthesis of liquid crystal intermediates, especially for the electronics sector. It plays a key role in controlling polarity and dielectric anisotropy during downstream aromatic ring modification, impacting the voltage holding ratio and temperature stability in finished display cells. Strict adherence to contamination and purity requirements ensures panel uniformity and display longevity. Industry compliance standards
Typical usage ratio
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5. Fine Fragrance and Aroma Intermediate for Industrial PerfumeryManufacturers in the aroma chemical supply chain source 4-Methylbenzonitrile for use in the synthesis of niche fragrance intermediates, especially those requiring clean, stable aromatic backbones. Its nitrile group enables downstream transformations—such as hydrogenation and etherification—leading to ingredients with defined volatilities and olfactory profiles for industrial-scale perfumery blending. Industry compliance standards
Typical usage ratio
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As a chemical manufacturer, producing 4-methylbenzonitrile means meeting the growing expectations of industries that demand reliability and quality at each stage of their process. Over many years in the field, we’ve seen this compound become more integral in the synthesis of fine chemicals, pharmaceuticals, and advanced materials. The reason is not just the molecular structure or purity levels, but the practical way this product fits into challenging industrial reactions. Every batch presents its own experience—from the way materials behave in our reactors to how technicians assess clarity and crystal form before sealing the drums. This closeness to the process shapes what we deliver and how we talk about 4-methylbenzonitrile.
Our 4-methylbenzonitrile, also called p-tolunitrile, carries a unique mix of predictability and flexibility. It shows up as a colorless to pale yellow liquid or crystalline solid, with a noticeable almond-like odor, which becomes obvious during quality checks. Consistent appearance and odor offer quick physical cues that our process is on the mark. Chemically, the methyl group at the para-position bestows more reactivity than benzonitrile alone, making it essential for both intermediates and targeted end products. While some look for product with a minimum purity just over 98%, we often batch several lots at 99.5% or above, simply because downstream processes—like selective hydrogenation or nucleophilic substitution—benefit from minimal contamination. Lower impurities mean smoother reactions, fewer unwanted side products, and less time spent purifying—which, over hundreds of kilos, translates directly to cost and labor savings for users.
Day-to-day, our tools for ensuring quality range from simple melting point checks to gas chromatographs that flag irregularities at low detection limits. Years ago, older purification methods delivered more variable results, finding solid flakes sticking to the sides of glassware or faint yellow hues that signaled dissolved trace by-products. With modern equipment and better-trained staff, our product rarely strays in color or composition. Even subtle shifts—sharper odors, altered crystal habits—prompt corrective measures before anything reaches a drum or container. It’s not an abstract promise of “high purity,” but a hands-on, careful approach that extends from raw material selection through to the final checks.
Over the last decade, our conversations with end users—formulators, synthetic chemists, process engineers—illustrate the breadth of uses. 4-methylbenzonitrile shines in pharmaceutical building blocks, from antipruritic active ingredients to anti-inflammatory agents. The molecule's nitrile group provides a crucial placeholder for later transformations: amidation, reduction to amines, or Grignard additions that build up complexity. It’s these steps where the consistency we offer most clearly shows up. Unintended byproducts often lead to batch reworks, or even regulatory questions later in drug development. Users share how switching to a more reliable supplier—even with the same nominal grade of material—can trim days from development timelines and shrink overall waste.
4-methylbenzonitrile has also found its way into liquid crystals, agrochemicals, dyes, and fragrance intermediates. Staff in R&D departments who experienced earlier supply interruptions or variable quality will recognize how a dependable product can unlock smoother synthesis. Unlike some niche intermediates, this compound resists oxidation and hydrolysis under standard storage, letting plants run extended campaigns without the anxiety of degradation. The stable shelf life plays well in lean inventory setups, which more companies pursue to control costs.
Comparing 4-methylbenzonitrile with its close relatives—such as benzonitrile, 2-methylbenzonitrile, or 3-methylbenzonitrile—reveals practical differences that matter on the production floor. Small shifts in substitution change physical properties and influence how a molecule behaves under catalysis. For example, our synthesis teams see the para-methyl group on 4-methylbenzonitrile reduce steric hindrance, making subsequent functionalization more straightforward than with ortho or meta isomers. During pilot-scale reactions, yields often rise and workup steps simplify, helping users scale up with confidence.
Benzonitrile itself, with no methyl group, can offer a cleaner starting point in reactions needing minimal branching. A methyl substituent alters electron density, making nucleophilic reactions faster or more selective. Downstream, the byproducts of 4-methylbenzonitrile degrade in predictable ways, helping plant operators plan effluent handling and avoid unforeseen regulatory slip-ups. This is less obvious with less-studied isomers. Our feedback loops with customers have led us to map potential trace impurities and refine post-synthesis washes to keep alkylbenzoic acids and related tars at near-undetectable levels. Each effort results in a product line aligned with not just specifications, but with the realities of industrial production.
The listed values for melting point, boiling range, and residual moisture may look like just numbers on a data sheet, but each relates to concrete experiences in our plant and at customer sites. Our product typically exhibits a melting range around 51-53°C and a boiling point near 230°C under atmospheric pressure. These figures guide storage choices, shipping logistics, and in-house solvent recovery. Sticky residues or off-odors, which surface if water or trace halides slip past controls, trigger a full line inspection—no shortcuts justify the risk of sending out non-conforming goods. Tight granularity in specifications, like limiting total impurities to less than 0.2%, comes from years troubleshooting actual complaints, not just copying industry standards.
Moisture holds particular importance. Even small amounts alter reactivity, creating foaming or clogging in reactors designed for anhydrous conditions. We mitigate this from the outset, using nitrogen blanketing during bottling and double-sealing containers. Teams check every drum before outbound shipment—not just for labeling, but for the tactile sense that signals a leak or improper fill. If a user notices clouding on opening or suspects microbial growth, our technical service team investigates and backs up findings with samples, rather than rushing to assign blame or pass on responsibility.
Long-term relationships with buyers have shaped our routines in ways few outside the plant might appreciate. Routine means more than producing the same material repeatedly—it's about learning from each batch, updating logs, tracking small deviations, and following up quickly whenever a deviation emerges. Labs often require batch-to-batch reproducibility within tight tolerances, and we've set up internal systems to record every analytical check. If there’s an outlier, both batch and analytical details go under review, with multiple departments weighing in. That way, users benefit from not just a snapshot report, but a historical record that proves our controls do more than meet the minimum. Batch consistency figures into questions as tangible as reaction time, solvent compatibility, and even powder handling on conveyors.
We’ve faced our share of production hurdles—unexpected feedstock volatility, equipment maintenance cycles, trickier than expected reaction kinetics. These events underline the importance of transparency. Whenever a challenge arises, we bring customers into the loop. That way, formulation adjustments or process modifications don’t get held up by misinformation or delayed updates. We consider each communication a form of partnership, where trust builds on forthright answers and delivery of what was promised, rather than apologies or shifting deadlines.
From decades of hands-on work, our teams approach 4-methylbenzonitrile with respect for its inherent hazards. We stress proper PPE and ventilation in the plant. Our loading crew reviews procedures regularly, especially as containers and bulk transport requirements change. Because we handle large volumes at a time, our technical and environmental staff double-check all transfer points for vapor release or cross-contamination. Customer feedback about odor, skin contact, or spillage gets pushed up the chain so that our own protocols evolve alongside user expectations.
Most of the incidents that reach our customer support line come from lapses in storing open drums or decanting without proper fume extraction. In response, we update best practice guides and encourage buyers to walk through their facilities with our safety engineers. In this way, plant staff bring practical insights that consultants working off paper or web searches just can’t match. Beyond regulatory compliance, we aim at making safety a working habit—reflected not only in our incident record but in the lack of call-backs for preventable issues.
As the original producer, our responsibility stretches from sourcing starting materials to managing finished stock. Up and down the supply chain, disruptions pop up—port delays, upstream shortages, transportation strikes. Our inventory buffers, local warehousing options, and production redundancy mean that even under strained conditions, we meet commitments. Buyers who switched from indirect channels saw firsthand the difference this makes; stop-gap shipments or generic material, which sometimes arrive from trading houses, often create more headaches than savings. The tight control we exercise lets us spot and correct potential shortfalls early, offering advance warning and, when needed, alternate solutions. This flexibility translates into real risk reduction for customers in time-sensitive campaigns.
Our plant network emphasizes proximity to shipping hubs and major industrial centers, minimizing lead time and exposure to unstable international routes. Material is packaged and labeled by staff that know the relevance of every barcode and seal, avoiding mix-ups during customs inspection. Our own logistics group maintains direct contact with freight partners—not through generic email chains, but with real-time updates and precise load tracking. In those rare moments a delivery hiccup surfaces, our team goes straight to the source, bypassing unnecessary middle layers.
Our relationships with buyers and their technical teams go beyond invoices and shipment confirmations. From the initial inquiry, both sides dig into the intended use, asking if any special considerations—like trace metal content or allergen exposure—play a part. Our staff frequently visits user facilities, running trials and training operators on best intake and storage practices. Insights from these field visits work their way into our finishing lines, driving upgrades to packaging and documentation that serve direct experience, not just regulatory requirements.
Some of our best product improvements came from these partnerships. One instance saw a pharmaceutical client struggling with reduced crystallization yields in downstream processing. Our technical manager reviewed the recipe, identified potential interference from ultra-trace impurities, and helped implement a finer filtration step. Shipping tailored lots with known impurity profiles resulted in measurable yield gains—a practical benefit for both sides. In another situation, a dye manufacturer facing inconsistent shades traced the issue to minute variations in feedstock. Together, we adjusted their reaction parameters and provided additional stability data, smoothing out their production curves.
In today’s market, regulatory scrutiny keeps climbing. Our teams track every lot of 4-methylbenzonitrile from raw input through final container. Documentation, from multistage synthesis logs to packaging details, stays accessible and verifiable. We make all analytical and safety information available on request, supporting audits and due diligence reviews. Experience has shown that incomplete records slow down projects, sometimes causing compliance headaches or lost opportunities during site inspections or third-party certification.
We keep up with evolving standards, whether those come from local authorities or major pharmaceutical codes. Our compliance team monitors REACH, TSCA, and similar frameworks, updating our offering as rules shift. On-boarding for new clients includes all required certificates and, if needed, in-person explanations of how our system matches auditor expectations. Over the years, we’ve learned that investing in reliable documentation saves all involved from costly corrections or regulatory back-and-forth.
Feedback from operators and technicians shapes more of our practices than policy manuals ever could. Every completed batch feeds lessons into the next—not just on output or purity, but how easy the product is to store, measure, and handle. Storage teams highlight the importance of moisture barriers during the rainy season, prompting the switch to improved drum liners. Logistics managers stress clear labeling and dispatch timing, leading us to overhaul transport procedures for tight delivery windows.
As technology evolves and target applications change, we adapt. Whether it’s integrating sensors for real-time QC checks or automating data transfers to back-office systems, hands-on improvement trumps abstract planning. Regular cross-training means plant staff and quality analysts speak the same language, ensuring anomalies get addressed before they affect customers. Industry magazines might focus on the headline figures, but day-to-day delivery builds on the small details—each tweak, each fix, and each round of feedback.
Producing 4-methylbenzonitrile provides more than a steady stream of output. It teaches patience, rewards diligence, and reflects in every customer call that pivots from a potential problem to a solved question. Supplying to industry giants and family-run shops alike, we've learned our value is measured by how we engage, adjust, and deliver—not just once, but with each new barrel, shipment, and inquiry. Every success supports the next, and every challenge pulls us back to the practical foundation—solid chemistry, prompt communication, and an unwavering eye for quality. From the plant gate to your door, our commitment to 4-methylbenzonitrile extends with every ounce produced.