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HS Code |
485759 |
| Chemical Name | 4-Chloro-2-nitroaniline |
| Molecular Formula | C6H5ClN2O2 |
| Molecular Weight | 172.57 g/mol |
| Cas Number | 89-63-4 |
| Appearance | Yellow to orange crystalline powder |
| Melting Point | 138-140 °C |
| Solubility In Water | Slightly soluble |
| Density | 1.51 g/cm³ |
| Pubchem Cid | 7043 |
| Inchi Key | JKJIJOMSZNKFNJ-UHFFFAOYSA-N |
As an accredited 4-Chloro-2-Nitroaniline factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | The 4-Chloro-2-Nitroaniline is packaged in a sealed 100-gram amber glass bottle with a secure screw cap and clear labeling. |
| Shipping | 4-Chloro-2-Nitroaniline is shipped in tightly sealed containers, protected from moisture, heat, and direct sunlight. It is typically packed according to hazardous materials regulations due to its toxic and potentially harmful nature. Proper labeling and documentation are required for safe transport, with handling procedures following all local and international shipping standards. |
| Storage | Store 4-Chloro-2-nitroaniline in a tightly sealed container in a cool, dry, and well-ventilated area away from direct sunlight and incompatible substances such as strong acids, bases, and oxidizing agents. Ensure the storage area is equipped to handle hazardous chemicals, and clearly label containers. Avoid sources of ignition and minimize exposure to heat and moisture. |
Applications of 4-Chloro-2-Nitroaniline in Industrial ManufacturingOur production-grade 4-Chloro-2-Nitroaniline supports several specialized sectors that demand strict compliance, high consistency, and secure downstream integration. Below, we detail verified industry pathways and their implemented practices. 1. Azo Dyes Intermediates for Textile Dyeing4-Chloro-2-Nitroaniline is widely used as a diazo component and coupling intermediate for manufacturing specific azo dyes utilized in cellulosic, polyamide, and wool fiber coloring. Textile dye makers select this material for high purity and batch-to-batch reproducibility, integrating it for the formation of disazo and monoazo dye chromophores. Control of nitro and chloro substitution patterns gives manufacturers fine-tuning of hue, solubility, and washfastness, essential for garment, yarn, and technical textile coloration. Industry compliance standards
Typical usage ratio
Downstream process integration
Final product types
2. Pigment Intermediates for Paints and Coatings4-Chloro-2-Nitroaniline functions as a vital intermediate in the production of organic pigments, specifically for yellow and orange azo pigments employed in coatings and plastics. Industrial paint and pigment manufacturers rely on its performance in downstream diazotization and coupling stages, ensuring precise hue control, dispersion stability, and lightfastness for architectural, automotive, and industrial applications. The impurity profile must meet pigment grade thresholds to prevent migration or color bleeding. Industry compliance standards
Typical usage ratio
Downstream process integration
Final product types
3. Pharmaceutical Intermediate SynthesisPharmaceutical manufacturers use 4-Chloro-2-Nitroaniline as a controlled intermediate during the synthesis of select active pharmaceutical ingredients, especially where aromatic amine chemistry supports core scaffold modifications. Material purity and traceability directly affect downstream process validation, and handling requires dedicated containment systems to avoid cross-contamination and ensure cGMP audit readiness. Scale-up batches are validated for analytical profile and process safety, and documented for regulatory submissions. Industry compliance standards
Typical usage ratio
Downstream process integration
Final product types
4. Agrochemical Synthesis Building BlocksLeading agrochemical manufacturers source 4-Chloro-2-Nitroaniline for the construction of herbicide, fungicide, and plant growth regulator molecules. Its electron-withdrawing nitro group and chloro substituent make it a preferred substrate in the nucleophilic aromatic substitution or reduction–coupling sequences. Production lines must ensure low heavy metal content and robust impurity controls to protect environmental safety and field application standards. Industry compliance standards
Typical usage ratio
Downstream process integration
Final product types
5. Polymer Additive and Stabilizer ManufacturingChemical processors apply 4-Chloro-2-Nitroaniline in the synthesis of stabilizer and color-imparting additives for specialty polymers. Its reactivity supports the construction of antioxidants and UV-stabilizers for plastics exposed to prolonged sunlight or mechanical stress. Polymer compounders demand precise metering and trace contaminant control to guarantee additive effectiveness and maintain polymer mechanical and optical properties. Industry compliance standards
Typical usage ratio
Downstream process integration
Final product types
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Every batch of 4-Chloro-2-Nitroaniline that leaves our facility reflects years of refining process control and raw material sourcing. Our daily focus revolves around providing a product our customers can trust, both in physical appearance and chemical purity. Over the years, we have developed our production to ensure that every lot maintains tight specifications. Each drum displays a yellow-to-orange crystalline powder, with purity levels consistently falling between 99% and 99.5%, checked by HPLC and GC methods. Moisture is tightly controlled, as is insolubles, because even a slight deviation can throw off downstream reactions. The reality inside the reactor is different from what it looks like in a textbook. Tiny changes in agitation rates and feed rates show up as shifts in particle size and filtration characteristics. Only a producer running the entire synthesis, downstream processing, and packaging can make sure these slight variations do not impact the final product.
The bulk of our output heads for use in agrochemical synthesis, especially as a building block for dyes and pigment intermediates. Users rely on its reactivity — the chloro and nitro groups lend themselves to versatile transformations. Many of the dyestuff and pigment workshops we supply use the product directly in their primary coupling reactions, and they highlight the clean conversion and minimal byproduct formation. If the starting point fails on impurities, those foreign species travel down the entire process chain, complicating cleanup and often dropping overall yields. Decades of close work with formulators have taught us that real downstream economy means more than buying cheap input — it is driven by smooth reactions, predictable filtration, and minimal waste, all starting with tight control on precursor quality.
After years of conversations with technical directors and line chemists, we rarely encounter requests for the same product in variable grades. Unlike some nitroaniline isomers or unrelated chloroanilines, 4-Chloro-2-Nitroaniline continues to stand apart because of the specific reaction pathways it enables. Other structural isomers such as 2-Chloro-4-Nitroaniline or 2-Nitro-4-Chloroaniline differ in how the substituents guide electrophilic aromatic substitution. In practical terms, this means they will not give the same color tones, reactivity, or downstream purity — no matter how “close” the data sheets look. Several customers who tried switching from our 4-chloro-2-nitroaniline to another isomer for cost reasons found that their intermediates came out with unpredictable color shades, substantial impurities, or troublesome recrystallization. Such issues are expensive, not only in product quality but in lost time and reworked batches.
As a manufacturer, years of experience have repeatedly shown that stable process parameters and reliable starting materials are the most important contributors to plant efficiency. The core of our production uses clean, direct chlorination followed by controlled nitration. These steps are monitored by our operators and checked analytically at every stage. The entire line runs with stainless steel to avoid introducing metallic contamination. Control of water content and handling of reaction gases must carry through to the filtration and drying stages, or sticky agglomerates or color variations impact the next step. Every kilo of material is handled by operators who know what variations look like—not just by eye but by tracking analytics and consistency trends over months and years.
Many users are not just interested in the molecule but in how it fits into their specific process. Over the years, conversations with end users in pigments and dyes exposed real-world problems, like batch-to-batch color variation and slow filtration. Close communication has helped us tweak drying, screening, and packaging. Some pigment makers want larger, dust-free crystals while others, like fine chemical syntheses, prefer smaller particle sizes for rapid dissolution. For bulk orders, we screen down to minimize fines that can clog handling equipment. We pay attention to feedback and implement changes where they matter—in the factory, not just on paper.
Production doesn’t just depend on modern equipment. The experience built on our factory floor cuts down trouble long before a batch ever leaves the easels. Several of our shift leaders have handled this route for more than a decade, solving real-time challenges that never show up in generic product brochures. Small operational tweaks, like running filters with specific mesh sizes or modifying solvent choices for certain customers, have resulted from long nights troubleshooting during actual runs. Years ago, a pigment plant flagged clumping during storage in humid weather. By examining the interaction between crystal habit and residual water, and then adjusting dryer settings, we managed to cut down caking complaints to near zero. This type of knowledge sticks because it’s been tested by hands-on work, not written once for a marketing team.
Everyone talks about fast delivery, but only direct control of inventory, loading, and documentation really delivers. Unlike sellers who source from third parties, we invoice, pack, and dispatch straight from our factory. For recurring customers, we keep extra safety stock, double-sealed packing, and can provide COA or extra analytical detail on request. Shipments pass customs with proper UN labeling and reach international ports by the agreed timeline. In recent years, more logistics companies require precise data to clear chemicals. We have worked directly with shippers, providing earlier booking confirmations and test reports that match exactly with each lot. Controlled warehousing and real-time data reduce risk of delays, especially for just-in-time supply chains.
Over the years, new buyers sometimes ask why two drums from two factories, advertised at the same purity, can perform so differently. The difference always shows up in the reality of your own plant. Impurities may pass basic GC but still introduce trouble: color fouling, unexpected traces that force end users to adjust future steps. Relying on the cheapest input creates hidden costs that surface as waste, downtime, or process headaches. Factory chemists who test real-world batches often tell us stories of chasing elusive yields, only to switch back to more reliable supply and watch problems vanish. Industry history backs this up: long-term relationships with proven producers save much more than cosmetic cost savings.
We work with buyers who ask tough questions. They want traceability from raw material to finished drum, full transparency on what goes into every batch, and a clear answer for every test result. We openly share process flows, clean data sets, and retain samples for cross-verification. Sometimes clients visit our site to look at agitation tanks, check discharge protocols, and see firsthand how pre-packing inspection works. This level of openness only comes when you make and ship your own product, validating all the way, rather than brokering from outside sources.
As times change, regulatory focus has grown—rightfully—on reducing emissions and safeguarding health. Twenty years ago, waste management was an afterthought. Now every new investment aims to cut down byproduct streams. We recover and treat spent acid from the nitration step, run scrubbers on any chlorination off-gas, and meticulously manage residues for safe landfill or incineration. Solvent recovery units recycle a significant portion of what was once discharge waste. We consider this the necessary cost of operating responsibly, especially as local authorities raise standards. Safety always comes first on our shop floor, from PPE requirements for staff to regular training refreshers and near-miss drills. Mistakes in chemical production do not end up as minor issues. By treating safety and sustainability as integral to our daily operations, we reinforce both the quality and consistency of our final product.
Markets shift quicker than theoretical projections. A big pigment customer might suddenly double demand, or new regulations could force a change in the allowable trace metal content. As a producer, we run parallel production lines when needed, immediately switching formulations if required by new contract specs or legislation. If required, extra purification steps or tighter screenings can be integrated for contract lots. Over the years, it’s become clear that the ability to tweak production in real time—without waiting for third-party adjustments—means repeat buyers know they can count on not just a specification, but a responsive manufacturing partner.
Years of feedback make us aware of the likely pain points users encounter downstream. Technical support isn’t about reading from a script, but about proven solutions tested in heavy-duty production. Pigment makers sometimes call about filtration slowness; our technical team has spent overtime in our own filtration hall pushing through clumped or overdried product to see firsthand how moisture adjustments can smooth out workflow. Innovation is born from these cycles of real-world usage, not one-off laboratory tweaks.
Lab purity above 99% often looks impressive on paper, but meaningful quality involves more parameters. Clarity of color, stability in extended storage, and absence of undesired isomers or trace metals all matter. Processed drums sent to clients have been held in our climate-controlled warehouse and monitored for changes in color and consistency year-round. Long-term pigment users report fewer inconsistencies and longer shelf life with this approach compared to suppliers with rapid turnover but little in-depth QC.
Competing 4-chloro-2-nitroaniline products on the market sometimes make claims of ultra-high purity. Our commitment is to real, practical performance, not just numbers. Many competitor batches end up with more fines, greater caking under humid storage, or contain trace impurities below regulatory limits that still trigger issues in high-end color applications. Our ongoing work with technical staff, coupled with careful monitoring of each production run, makes sure that every lot matches customer expectations–not just for purity, but for reproducibility and problem-free processing.
Industry requirements never stay static. Regulatory limits on specific trace impurities grow tighter each year. Market feedback calls for lower dust levels, improved flowability, and tighter color consistency. We keep investing in filtration technology, monitoring for micro-contaminants, and refining drying and milling to adapt to these real-world asks. Staff participate in ongoing technical training; site audits ensure nothing is overlooked. These measures mean we stay one step ahead—not just on paper, but on the warehouse floor and in every delivered batch.
For buyers serious about 4-chloro-2-nitroaniline as a production input, the key value comes from tight process control, proven transparency, and proven experience in real chemical manufacturing. Feedback circles between production, QC, and end user inform every process change. Our decades of operation show that industry moves not on slogans, but on material that works every time, in every batch, no matter the volume. This is the product of long-standing expertise and direct, hands-on engagement with all aspects of synthesis, handling, and shipping—offering peace of mind and reliable results to those who depend on this key building block.
