3-Octyne

    • Product Name: 3-Octyne
    • Alias: boctyne
    • Einecs: 203-890-8
    • Mininmum Order: 1 g
    • Factroy Site: Yudu County, Ganzhou, Jiangxi, China
    • Price Inquiry: admin@ascent-chem.com
    • Manufacturer: Ascent Petrochem Holdings Co., Limited
    • CONTACT NOW
    Specifications

    HS Code

    818946

    Chemical Name 3-Octyne
    Cas Number 627-19-0
    Molecular Formula C8H14
    Molar Mass 110.20 g/mol
    Appearance Colorless liquid
    Boiling Point 131-132 °C
    Melting Point -74 °C
    Density 0.749 g/cm³ at 20 °C
    Refractive Index 1.422
    Flash Point 18 °C
    Structural Formula CH3CH2CH2C≡CCH2CH2CH3
    Synonyms Oct-3-yne, Dipropylacetylene

    As an accredited 3-Octyne factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing The packaging for 3-Octyne (25g) consists of a sealed amber glass bottle with a secure cap and a clear hazard label.
    Shipping 3-Octyne should be shipped in tightly sealed containers, away from sources of ignition, heat, and incompatible substances. It must be labeled as a flammable liquid and handled according to local, national, and international transport regulations (such as DOT, IATA, IMDG). Use appropriate protective packaging to prevent leaks during transit.
    Storage 3-Octyne should be stored in a tightly closed, clearly labeled container in a cool, dry, and well-ventilated area, away from sources of ignition, heat, and incompatible materials such as strong oxidizers. Protect the storage area from direct sunlight and moisture. Ensure containers are grounded to prevent static discharge. Follow all relevant safety guidelines and regulations for flammable liquids.
    Application of 3-Octyne

    Applications of 3-Octyne in Industrial Manufacturing

    3-Octyne serves as a strategic intermediate in several industrial sectors, where its unique triple bond structure drives key transformations in organic synthesis and advanced material production. As an established chemical manufacturer, we empower downstream producers to achieve consistent formulation and quality outcomes by supplying high-purity 3-Octyne tailored for specialized use across defined application segments.

    1. Advanced Organic Synthesis for Fine Chemicals

    3-Octyne acts as a critical building block in the synthesis of fine chemicals, including specialty ligands and customized alkyne derivatives, due to its controlled reactivity and compatibility with metal-catalyzed coupling reactions. Research and development teams in fine chemical plants rely on this material for the precision construction of C–C bonds, particularly in high-value segments where purity, yield consistency, and traceability are essential throughout multi-step syntheses. Integration of 3-Octyne occurs during Sonogashira, Glaser, and Eglinton coupling stages, directly impacting the structural fidelity and final output characteristics of alkynyl-containing products.

    Industry compliance standards

    • REACH Regulation (EU)
    • ISO 9001:2015 Quality Management System
    • APIC GMP for Pharmaceutical Excipients (if used as a precursor for pharma intermediates)
    • OECD Principles on Chemical Safety

    Typical usage ratio

    • 10–30 mol% relative to target product, optimized case-by-case for coupling efficiency and downstream functionalization yield

    Downstream process integration

    • Input stage in catalytic coupling; introduced after substrate activation and degassing, prior to the addition of catalyst (e.g., Pd/Cu systems)

    Final product types

    • Specialty ligands for catalysis
    • Functionalized phenylacetylenes
    • Extended π-system dyes
    • Precursor blocks for advanced agrochemicals

    2. Catalyst and Ligand Manufacturing

    Producers of organometallic catalysts incorporate 3-Octyne as a selective alkyne source for fine-tuning ligand backbones and constructing chiral induction centers. The geometric rigidity and steric attributes impart uniform electronic properties to resultant catalysts, which is especially significant in asymmetric hydrogenation and cross-coupling catalyst lines. These applications demand batch-to-batch reproducibility and trace impurity control, achieved through optimized 3-Octyne integration during ligand assembly and metal complexation routines.

    Industry compliance standards

    • ISO 17034:2016 Reference Material Production
    • ISO 9001:2015 Quality Management System
    • Responsible Care Global Charter
    • REACH Regulation (EU)

    Typical usage ratio

    • 3–12 wt% as a function of desired ligand architecture and specific metal binding site configuration requirements

    Downstream process integration

    • Core structure introduced during monomeric ligand formation, ahead of complexation with metal precursors under inert atmospheric conditions

    Final product types

    • Chiral phosphine ligands
    • Bispyridyl alkynes
    • Palladium and ruthenium catalyst pre-cursors
    • Structure-guided organometallic scaffolds for process catalysis

    3. Pharmaceutical Intermediate Synthesis

    3-Octyne finds targeted application in the synthesis of pharmaceutical intermediates, especially for manufacturing alkynyl functional groups in compounds used as active pharmaceutical ingredients (APIs). Process chemists leverage its precise triple-bond configuration to maximize regioselective reactivity in step-wise API precursor assembly. Compliance with pharmaceutical quality standards is enforced throughout the handling and transformation stages, from initial coupling to downstream hydrogenation and protecting group management.

    Industry compliance standards

    • ICH Q7 – Good Manufacturing Practice for Active Pharmaceutical Ingredients
    • US Pharmacopeia <823>
    • EU GMP for Starting Materials
    • REACH and local API precursor regulations

    Typical usage ratio

    • 5–20 mol% in the core assembly stage, adjustable based on stoichiometry and specific intermediate synthesis pathway

    Downstream process integration

    • Key reactant in intermediate formation, introduced at the coupling or alkylation step before selectivity-driven purification and downstream transformations

    Final product types

    • Alkynyl-substituted intermediates for oncology and CNS-targeting drugs
    • Precursors to small molecule kinase inhibitors
    • Raw materials for anti-viral API development
    • Process intermediates used in high-potency API lines

    4. Material Science & Polymer Modification

    Material science innovators and polymer manufacturers employ 3-Octyne for molecular modification of specialty polymers and engineered materials, where its unsaturated carbon bond structure allows for tailored post-polymerization reactions. Cross-linking and functionalization with 3-Octyne permit control over final mechanical and electronic properties. Typically, its incorporation occurs under controlled conditions to ensure homogenous distribution and tightly regulated polymer architecture, responding to client product specifications and strict regulatory handling guidelines.

    Industry compliance standards

    • ISO 14001:2015 Environmental Management Systems
    • ISO 9001:2015 Quality Management
    • RoHS Directive (for electronics applications)
    • REACH (EC) No 1907/2006

    Typical usage ratio

    • 0.2–2.5 wt% for chain modification or end-group functionalization; adjusted to achieve targeted polymer cross-linking density or conductivity profiles

    Downstream process integration

    • Post-polymerization addition prior to curing or as a reactant during in situ polymer network assembly, integrated via solution or melt-phase addition depending on matrix material

    Final product types

    • Modified conductive polymers
    • Specialty elastomer blends
    • UV-curable resins
    • High-strength coatings for electronics encapsulation

    Free Quote

    Competitive 3-Octyne prices that fit your budget—flexible terms and customized quotes for every order.

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    Certification & Compliance
    More Introduction

    3-Octyne: A Chemical Manufacturer’s Perspective

    Introducing 3-Octyne – Insights from Years on the Production Line

    In this corner of the specialty chemical world, raw hydrocarbons shape more transformations than most people ever realize. Among the many products we distill, synthesize, test, and vouch for, 3-Octyne often stands apart—not just for its technical make-up, but for the practical stories attached to every barrel. 3-Octyne sits among those mid-length, unsaturated aliphatic hydrocarbons where every carbon and triple bond matters for performance. This colorless, mobile liquid comes from roots deep in petrochemical engineering, and the journey from raw feedstock to a trusted bottle is one that reflects both experience and steady hands on the production line.

    Precision in Structure, Precision in Application

    The chemical structure of 3-Octyne is simple enough for any organic chemist, but hands-on experience brings out the nuances. Its formula, C8H14, features a triple bond between the third and fourth carbons, giving it certain physical and chemical strengths compared to other alkyne isomers. Placing the triple bond at the third position rather than terminal or near-terminal positions brings particular stability, both during storage and application. Not every alkyne can claim this. In our facility, where we handle fragmentation, distillation, and fine purification daily, we see this stability streamline every subsequent step in formulation or further synthesis. The product flows cleanly through the process chain with minimal side reactions or degradation—a direct payoff in fewer rejected batches and less line downtime.

    Over the years, we have measured the boiling point, density, and purity of countless batches. Our standard offering runs at a minimum purity of 98%, and compounds are analyzed by established methods like gas chromatography to verify every delivery. Each fractional change in physical properties reveals a lot about feedstock quality, reaction conditions, and potential impurities. Keeping specifications tight may sound simple, but in practice, it requires rigorous control—choice of catalyst, inhibitor management, and regular calibration of our detectors. The consistency of each lot shapes our reliability in the eyes of our long-term technical buyers, who have little tolerance for disruptions in their formulations or pilot plants.

    How Buyers Use 3-Octyne in Industry and Research

    The real story of 3-Octyne stretches beyond the factory floor. This compound serves as a core building block for several organic syntheses in academic labs and in scale-up environments. The triple bond at an internal carbon works as a functional handle during coupling, cyclization, and addition reactions, allowing synthetic chemists to weave it into a larger tapestry of intermediates. Pharmaceutical labs often use 3-Octyne for the development of specialty compounds—sometimes for the assembly of molecular scaffolds, sometimes as a reactant that injects new functionality into a molecule halfway through a multi-step process. Agricultural chemists blend it into certain protective chemistries, or use it to explore new modes of action in crop science.

    Because 3-Octyne resists unwanted side reactions more than terminal alkynes, it often gives higher selectivity during catalytic transformations. Many research groups have compared yields and by-products, tracking the difference between 3-Octyne and its positional isomers. In catalytic hydrogenation, for example, internal alkynes like 3-Octyne produce fewer over-reduction products than their terminal cousins, which appeals to both academic investigators and scale-up engineers. Our quality team keeps in touch with clients who publish their work, and those feedback loops shape the tweaks we make to process parameters and final specifications.

    Distinctions Between 3-Octyne and Other Alkynes

    In our direct experience, not all alkynes play the same way in the plant or in the field. Compared to terminal alkynes like 1-Octyne, 3-Octyne exhibits less reactivity toward atmospheric oxidation—something we track closely during packaging and shipment. This property saves users headaches with spontaneous formation of side products or gums, and eases the burden of long-term storage. Internal alkynes also carry slightly higher boiling points and reduced volatility, reducing worker exposure during large-volume transfer. Our packaging team sees the reduced evaporation at each decant and loading session, which has clear value for both safety and economic losses.

    Chemists sometimes ask for 2-Octyne or 4-Octyne, but the location of the triple bond influences more than just molecular geometry. For catalysts used in coupling or addition processes, the interaction with the π-system at carbon three may yield subtle differences in activation or selectivity. One example we see in industry involves metal-catalyzed cross-coupling reactions where the internal position of the triple bond facilitates better outcomes for specific ligands. Labs working on functionalized materials prefer this property, and we provide data to support project work as they troubleshoot their own procedures. From a manufacturing standpoint, consistent handling means less downtime fighting side reactions, improved isolation of the target product, and fewer environmental excursions.

    Specification and Handling—Managed by Experience, Validated by Results

    Our facility operates under strict internal guidelines and regional regulations designed around both quality and sustainability. We document batch genealogy, pack 3-Octyne under inert atmospheres, and maintain contamination controls for every run. The purity window that specialty users demand—often 98% or better—emerges from repetitive, real-world process control. Regular runs reveal the quirks and occasional surprises of long-chain alkynes, reminding our technical team of the human element in chemical production. Each operator, each shift, each maintenance interval offers learning moments that feed back into more efficient operations. The laboratory and production work in tandem: each chromatogram, each distillation run, and each finished batch links us to predictable quality.

    The differences in physical handling cannot be overstated. Small fluctuations in storage temperature, for instance, pose fewer risks with 3-Octyne than with lighter hydrocarbons or more reactive isomers. As we prepare shipments for research clients or scaling partners, we draw confidence from our incident reports, knowing that stability and manageable vapor pressure reduce both hazard and waste. Our technical support team stays ready to answer questions—less to sell a product, more to share lessons from the factory floor about real-life experiences with alkyne packaging, storage, and use.

    Ethics, Traceability, and Long-Term Stewardship

    Stakeholders want to know where their chemicals came from, how they were made, and whether the process meets more than the minimum standards. For us, this means tracing raw materials, keeping up with new environmental regulations, and pushing for reduction of waste streams during production. 3-Octyne production generates a unique waste profile, and we have installed equipment to recover as much solvent as possible, target hydrocarbon recycling, and minimize emissions. Improvement often comes from staff suggestions—small operational tweaks or safety process reviews—rather than merely from outside audits or mandatory upgrades. Our regular investment in technical training for operators and analytical staff ensures repeatability and expertise.

    Traceability goes deeper than paperwork. We track raw batch receipts, lot integrity, and chain of custody across the supply chain. When customers face audits or product recalls, we can provide evidence of each batch’s origin and handling, all the way back to the aggregation of input materials. Technical buyers and regulatory teams ask pointed questions; we value those, because strong records and transparently shared data have formed the backbone of long client partnerships. Regulators and auditors step onto our production floor, observe procedures, and examine the devices that guarantee product separation, environmental protection, and worker safety. Feedback loops develop not just from external pressure but from an internal desire to improve.

    Common Questions, Everyday Challenges – and the Path Forward

    Clients from universities, contract manufacturing sites, and multinational laboratories reach out regularly with focused questions: How does your 3-Octyne handle in high-shear mixing? Does it perform differently in non-polar solvents versus polar ones? What are the necessary safety considerations during bulk transfer? Each question means a deliberate review of both literature and factory records, sometimes resulting in phone calls between technical leads on both sides of the transaction.

    One of the challenges our team has addressed involves material compatibility—especially with seals, gaskets, and containers exposed to triple-bond reactivity. After processing and regular field returns, we have shifted some packaging types from generic polymers to higher-grade fluoropolymers, cutting the risk of degradation or contamination. We train our loading staff to monitor air ingress, not only for their own safety but to avoid batch loss from oxidation. Over time, these changes, informed by hands-on feedback rather than theory or marketing, have improved the safety and shelf-life offered in each package.

    Case Examples – Direct Feedback from Industrial and Academic Labs

    An example from a long-time pharmaceutical partner helps illustrate this point. Their synthesis sequence required introducing a C8 internal alkyne at a later stage, but prior suppliers delivered inconsistent purity. During one summer several years ago, batches they sourced elsewhere failed QC threshold tests for side products. By the time they switched to direct supply from our plant, their in-house team compared chromatographs and found a marked drop in unpredictable by-products. Yield on their next synthetic step improved by double-digit percentages, and they set aside more time for process development thanks to fewer purification cycles.

    Another case involved a research group exploring new ligand environments for metal-catalyzed cross-couplings. Their literature review hinted at better conversion rates with 3-Octyne’s triple bond at an internal site, but field experience told them the main obstacle was handling volatility and unwanted oxidative degradation. With our standard stabilization protocol and guidance on ideal storage practices, incidents of bottle browning or pressure build-up dropped, allowing them to focus on core research instead of troubleshooting material sourcing problems.

    Collaborative Innovation—From Production to Laboratory Bench

    The evolution of a product like 3-Octyne owes much to the conversations behind lab benches and plant control rooms. We encourage teams from both sides to visit, compare notes, and suggest incremental improvements—whether that means tweaking the purification train, adjusting acceptable specification ranges, or swapping packaging materials for real-world benefits. These improvements derive from measured outcomes and remembered mistakes, not from slide decks or marketing brainstorms.

    Our laboratory and production teams rarely work in a vacuum. Regular technical exchanges with downstream users bring fresh data on reaction profiles, safety incidents, and storage outcomes. Problems such as raw material contamination, batch variability, or unexpected odor development have been solved not by relying on generic solutions, but by deep-dive investigations spanning both analytical and operations teams. A bottleneck resolved, a runaway reaction prevented, a workplace injury averted—these enrich our collective experience and carry forward into every new production season.

    Quality and Safety—Rooted in Decades of Cumulative Experience

    At the core of reliable 3-Octyne production stands a commitment to safety, precision, and accountability. We invest in staff training, from entry-level technicians to veteran plant supervisors. Emergency preparedness and spill mitigation are not compliance obligations but shared responsibilities, logged, trained, and revisited after every near miss and accident. Every drum and bottle handled by the shipping team reflects practices honed through cycles of challenge and response.

    Incidents like a mislabeled drum or a missed QC checkpoint prompt immediate investigations, followed by company-wide discussions that lead to new checklists, or in some cases, technology upgrades. Each year, we replace or retrofit older equipment, not just to “modernize” in a cosmetic sense, but to build robustness against potential process upsets. This hands-on tradition of self-critique and peer review makes the difference that customers notice—often without realizing the invisible layers of redundancy and care built into each delivery.

    Sustainability and Responsibility in Chemical Manufacturing

    Responsibility does not stop at the factory gate. For us, sustainability means reducing resource consumption and emissions, adopting more efficient catalysts, and participating in local initiatives to monitor and improve water usage. Every improvement counts, whether that means tighter recovery of spent solvents, investing in vapor recovery units, or partnering with downstream users on recycling programs for secondary containers and bulk tanks.

    Transparency with our community, regulatory agencies, and supply chain partners deepens trust. Annual reviews, staff consultations, and customer feedback all play a part in shaping the direction of our 3-Octyne operations. Demand for disclosure and accountability is not a passing trend; it forms the foundation for company culture and long-term business resilience.

    Trust Built on Real Expertise and Hands-On Production

    In sum, our story with 3-Octyne stands as a record of chemical know-how, forged between test benches and control panels. It is the product of controlled chemistry, operational vigilance, and a personal commitment from each team member involved in every kilo produced and shipped. The difference between a commodity chemical and a reliable reagent—one trusted by innovators and research leaders alike—often comes down to these day-in, day-out practices rooted in genuine operational experience. If 3-Octyne’s character as a specialty alkyne seems understated, those who rely upon it for their science or manufacturing rely more on consistency, safety, and support than on flashy claims. That’s what decades of real chemical manufacturing has taught us, and what we bring forward each day with every new batch.

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