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HS Code |
744979 |
| Chemical Name | 3-Nitroaniline |
| Iupac Name | 3-nitroaniline |
| Cas Number | 99-09-2 |
| Molecular Formula | C6H6N2O2 |
| Molar Mass | 138.13 g/mol |
| Appearance | Yellow crystalline solid |
| Melting Point | 114-117 °C |
| Boiling Point | 306 °C |
| Density | 1.38 g/cm³ |
| Solubility In Water | Slightly soluble |
| Flash Point | 152 °C |
| Pubchem Cid | 7468 |
As an accredited 3-Nitroaniline factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 250 g of 3-Nitroaniline is packaged in a tightly sealed amber glass bottle, clearly labeled with hazard warnings and chemical details. |
| Shipping | 3-Nitroaniline should be shipped in tightly sealed containers, protected from physical damage and moisture. The chemical is classified as hazardous and must follow appropriate regulations, including labeling and documentation. It should be transported in accordance with UN 1662, packed in compliance with international and local safety guidelines for toxic solids. |
| Storage | 3-Nitroaniline should be stored in a tightly closed container in a cool, dry, and well-ventilated area away from direct sunlight, heat sources, and incompatible substances such as strong oxidizing agents and acids. Keep it away from ignition sources. Use secondary containment to prevent spills, and clearly label the storage area. Store at room temperature and follow all relevant safety guidelines. |
Applications of 3-Nitroaniline in Industrial ManufacturingAs a direct manufacturer of 3-Nitroaniline, we supply this intermediate to industries requiring consistent quality and regulatory adherence. Our production supports key sectors where 3-Nitroaniline serves as a critical building block or functional component, enabling the downstream manufacture of advanced specialty and commodity products. Below are precise industrial application scenarios that leverage the unique performance and chemical characteristics of 3-Nitroaniline. 1. Synthesis of Azo Dyes for TextilesTextile dye manufacturers utilize 3-Nitroaniline for the synthesis of high-performance azo dyes, where it acts as a diazo component delivering chromatic stability and specific shade profiles required by fabric producers. The integration of 3-Nitroaniline allows formulators to control dye structure, fastness, and intensity, which are essential for garments and technical textiles meeting international quality criteria. Industry compliance standards
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2. Manufacture of Agricultural Chemical IntermediatesThe crop protection industry uses 3-Nitroaniline as a core intermediate for constructing complex heterocyclic ring systems essential in certain pre- and post-emergence herbicides as well as fungicides. Its specific aromatic substitution pattern permits selective nitration, sulfonation, and amine transformations, enabling efficient scale-up of active ingredient synthesis under controlled regulatory environments. Industry compliance standards
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3. Pharmaceutical Active Intermediate SynthesisAPI plants employ 3-Nitroaniline in the synthesis of complex APIs, particularly for anti-tumor drugs, analgesics, and anti-hypertensive agents, where its electronic properties facilitate critical nitration or amination. The predictable reactivity of the nitroaniline group enables efficient coupling for subsequent steps in heterocycle and aromatic amine-based drug structures, supporting the stringent quality norms demanded by global pharma supply chains. Industry compliance standards
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4. High-Performance Pigment PrecursorsPigment manufacturers integrate 3-Nitroaniline in the controlled synthesis of yellow, orange, or red monoazo pigments. The compound’s specific electronic attributes determine hue, opacity, and dispersibility in inks, coatings, and plastics. Its reliability under high-temperature coupling ensures batch-to-batch shade reproducibility, which remains critical for automotive, plastic, and industrial paint manufacturers. Industry compliance standards
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5. Photographic Chemical ReagentsPhotographic film and print manufacturers incorporate 3-Nitroaniline as a precursor for synthesizing light-sensitive couplers and dye-forming agents used within color film layers and photographic papers. Its structural specificity enables precise color tuning in coupler compounds, critical for color reproduction accuracy in professional imaging products, while meeting stringent safety and migration controls. Industry compliance standards
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Working as a chemical manufacturer demands a careful balance between innovation and reliability. Our focus has always been on serving real needs from industries relying on core building blocks like 3-Nitroaniline. Years of hands-on experience in producing aromatic amine derivatives taught us the value of purity, batch consistency, and process transparency—not just as buzzwords, but as principles that underpin every kilogram of material we ship.
3-Nitroaniline appears as a pale yellow to brownish crystalline solid, building its reputation through performance in dye and pharmaceutical fields. Our in-house process ensures a 99%+ purity level, using stringent controlled synthesis and filtration stages. Aniline starts the story; then, via direct nitration, we land the product at the required para position. The result is a consistent 3-nitroaniline profile, minimizing by-product contamination—an edge we have honed through years of optimizations to meet our partners’ strictest standards.
Dye manufacturing forms the backbone of commercial 3-nitroaniline demand. In the hands of textile and pigment formulators, this compound unlocks yellow, orange, and red colorants constructed through azo coupling. Working with material packed in moisture-resistant bags, textile partners report batch-to-batch shade consistency that only comes with a stable feedstock. Even small impurities can impact color purity or lightfastness, causing headaches during production or even recalls for off-spec goods. Our facility prioritizes tight control, starting with raw feedstocks and running ongoing in-process purity checks to prevent these problems before they leave our doors.
Pharmaceutical clients value 3-nitroaniline for a different reason. Its benzene core and nitro group open pathways for synthetic intermediates with targeted pharmacological properties. In new drug development, chemists build on 3-nitroaniline to design molecules active against specific targets—metabolizing the nitro group or swapping amine positions to adjust solubility and reactivity. Our production team supports these applications with technical documentation that details trace metal content, solvent residues, and micro impurities—items that sometimes go unchecked at trading houses, creating headaches for drug formulators working under regulatory oversight. We’ve collaborated directly with labs on multi-kilogram scale-ups, tuning our process to ensure it fits with strict GMP or validation requirements.
Compared to its isomers, namely 2-nitroaniline (ortho-) and 4-nitroaniline (para-), 3-nitroaniline (meta-) brings specific advantages to each synthesis route. The meta positioning blocks certain side reactions, often improving yields in multi-step syntheses facing selectivity challenges. Textile chemists sometimes request para- or ortho- isomers, but the meta form acts as a key precursor in a range of specialty azo dyes and developer compounds found nowhere else. We have tested all three in the lab. 3-nitroaniline demonstrates better compatibility with certain coupling agents—not just in dye houses but also in pigment frit applications, where melt-point control matters and impurity migration causes downstream issues.
Another notable difference comes up during storage and handling. While 4-nitroaniline tends to crystallize in finer particles and cake after humidity exposure, 3-nitroaniline holds up better in areas with moderate temperature swings. Lab staff working with large-scale ultrasonic reactors have commented on improved flow when charging hoppers with our batches. That detail came out from daily operations feedback, shaping the way we pack and ship. Bulk users in the pigment and coating sector rely on this handling property to avoid downtime—one of those practical considerations that traders overlook, but manufacturers build into every batch produced.
Real know-how in 3-nitroaniline manufacturing starts with precise reaction controls and disciplined waste management. Incidents of mixed isomer byproducts or colored impurities often link back to insufficient temperature regulation during nitration or incomplete workup steps. Our technicians monitor color, titrable acid, and byproduct profile at each filter cake—sharing real-time results on the plant floor. Years back, a persistent off-color issue led us to tweak our quench protocol, swapping water flow direction and reviewing insulation settings. These types of on-the-ground interventions build up over time, translating into products that deliver on performance expectations.
Some importers and brokers push generic material sourced from third-party origins with fewer checks, but we don’t compromise. Every ton produced comes from our own lines, built and staffed to meet the requirements of companies making high-value goods. We chart every lot to compare performance data, checking color strength in dye tests using industry-standard CIE and ISO test cards or as requested by formulating chemists. Surface area, particle size distribution, moisture readings—these are not decorative specifications but everyday tools for ensuring what leaves our facility matches what landed in your qualifying trials months before.
A common trap lies in chasing lower upfront costs by selecting material from non-specialist suppliers—something we have seen many times. Early in our business, a keen client shared issues traced to a previous source: product from a non-dedicated reactor not fully purged between runs. The resulting low-level contamination ended up in a final pigment paste, causing color drift and shelf-life complaints down their chain. Our solution involved traceability systems, with each tote or drum mapped to a production log, ensuring the same input/output data for every repeat order.
As regulatory frameworks toughen, especially in North America and the European Union, both compliance and full transparency have become non-negotiable. Though trading houses may supply base-level documentation, only a direct manufacturer’s view gives the complete story. Our safety data sheets compile real measured data, not just literature values. Every batch certificate reflects actual outcomes—residual solvents, heavy metals, moisture, and visual inspections recorded per shipment.
We share use cases with clients looking to upgrade processes or solve application-specific challenges. For pigment formulators, we have provided side-by-side migration data comparing 3-nitroaniline to structurally similar compounds. In the case of inkjet development, tighter particle size distributions, controlled flow, and reliable shelf-life stability all tracked directly to our careful process optimizations. For pharmaceutical leads, our team reports specific impurity profiles down to single-digit parts-per-million, supporting robust regulatory submissions and validations for scaled intermediates.
The foundation of these results lies in pushing past a “one size fits all” approach. Requests for custom variants, such as lower moisture or lower dust content, feed directly into our pilot line. We adopted finer filtration media for dye stuff manufacturers who found dust a root cause for machine fouling. That single adjustment reduced downstream cleaning costs for three facilities, nearly eliminating one cause of unplanned stoppages.
A technical grade product sometimes comes up short when facing the day-to-day realities of customer processes. Variability impairs repeatability on the production line, leading to inefficiency, loss of product, and client frustration. Our own approach has led us to revisit filtration and drying stages, constantly evaluating solvent recovery rates and filter cake handling to improve every batch. We’ve learned that open communication with end-users exposes issues sooner, often before they flow downstream.
Early batches taught us difficult lessons about scale-up. As we transitioned from lab-research to full-scale reactors, subtle shifts in stirrer speed or cooling time created higher byproduct levels—a fact only uncovered through direct dialogue with users. By keeping raw data transparent and acting on field feedback, we continually align our process controls with the practical realities of marketplace requirements.
In one case, a dye customer found pinhole faults after scale-up. Our on-site QC worked side by side with their engineers, adjusting both formulation and drying cycles. This iterative cycle tightened limits, reducing downtime by over twenty percent and cutting losses on faulty fabric runs. Faced with these challenges, we cemented a process of ongoing feedback, transforming single orders into long-standing partnerships where both sides gain from continuous improvement.
The chemical manufacturing world has no room for guesswork, especially when thousands of tons flow downstream to critical uses. Consistency begins at the earliest stage: procurement of raw aniline. We work with vetted suppliers, demanding purity and full spectrum analysis, not just COA paperwork. Each delivery receives pre-qualification before entering production, caught early before it can compromise downstream synthesis.
Batch production cycles involve redundancy in quality checks—color, melting point, moisture, and byproduct scan—before, during, and post reaction. On the floor, operators log readings into a central traceability system. By comparing historical data, subtle drifts in process variables appear before they threaten quality. Our teams have learned over time to trust the data and not rely solely on routine; a spike in off-spec readings flagged changes in vessel baffle design years back. That episode led to a plant-wide modification, which in turn reduced byproduct carryover permanently.
Clients in pharma and pigment production alike depend on predictability. They value continuous production, reliable performance, and the absence of unwanted “surprises” brought by inconsistent raw input. Our manufacturing model builds these outputs through proven process control, ongoing communication, and a shared sense of responsibility for end performance.
Modern chemical operations face increasing demands for sustainable and safe production. Over time, environmental stewardship has shifted from a cost to a core responsibility. During our refinement of the 3-nitroaniline process, efforts focused on minimizing byproduct streams and recovering usable intermediates for secondary applications where possible.
Our facility includes installed scrubbers and advanced filtration units, capturing nitrous fumes and waste acids before they enter wider waste streams. Spent acid recovery units return value to upstream processors and reduce environmental footprint. We document and monitor effluent characteristics, aligning output streams with local and international regulatory standards. Emerging technologies, such as membrane filtration and digital sensing, help us adapt as regulations shift.
Minimizing waste aligns economic interests with environmental protection—a lesson learned both from experience and necessity, as partners insist on documented proof of compliance before granting supply agreements. Only a direct manufacturing operation assumes this level of responsibility and delivers on it, since the know-how from process to disposal stays under one roof.
Meeting demand for 3-nitroaniline goes beyond fulfilling an order sheet. We invest in technical support and collaborative problem solving at every project stage. Whether troubleshooting dye shade drift, qualifying feedstocks for drug intermediates, or scaling new variants, our production and QA teams engage directly with end users. Root-cause analysis and fine-tuning are not afterthoughts for us—these practices anchor our value as a manufacturer.
In one example, a new customer switching from a competitor faced ongoing blockages during pigment paste runs. Fielding samples, we identified fine particle agglomeration linked to upstream packing. Trials with modified drying and sieving removed the root cause, restoring flow and reducing batch scrap rates. That story reflects the tangible gains that come from a relationship with a producer embedded in the technical side.
As markets demand ever-tighter specs and regulatory pressures grow, being able to trace every batch from first step to final shipment offers peace of mind our customers count on. We stay ready to share process data, batch records, and supporting technical literature on request. For us, supporting partners means being a source of knowledge as much as a provider of material.
Decades in this industry shaped a culture where continuous improvement runs at the heart of our work on 3-nitroaniline. Whether refining purification methods, introducing advanced QC tools, or trialing greener solvents at pilot scale, our outlook stays grounded in delivering not just the same product, but a better one, each batch.
Shifts in end-use demand push us to adapt. As pigment makers face new regulations on contaminant levels or pharmaceutical formulators seek tighter specification tolerance, we allocate R&D resources to innovate, refine, and meet these challenges head-on. Customers interact directly with our technical and production staff, shaping the ongoing story of product quality with real-world insights. New testing protocols, online process monitors, and digital tracking tools all build on client interaction, feeding the improvement loop that lifts quality year after year.
Our view is clear: reliable chemical manufacturing builds long-term value for everyone. We plan investments in plant upgrades and technical training based on real data and supply chain partnerships, not on volume alone. By investing in robust production and honest communication, we earn the trust and repeat business that fuels both our own growth and that of our customers.
Having produced and supplied 3-nitroaniline for years, we understand well how real manufacturing quality translates directly to customer results. Every technical advance, process tweak, or compliance step stems from an ongoing collaboration with those who depend on our product. That feedback shapes every decision, from choosing raw suppliers to investing in new lab instrumentation for tighter impurity analysis.
More than a simple commodity, 3-nitroaniline connects deep into chemical manufacturing chains. Real results—be they bright and durable dyes, stable pharmaceutical intermediates, or long-lasting pigments—rely not only on chemistry but on the people and systems behind every batch. By building on proven expertise, practicing transparent communication, and never losing focus on reliability and responsibility, we stake our reputation on supporting every customer who places their confidence in our hands.