3-Methylaniline

    • Product Name: 3-Methylaniline
    • Alias: m-Toluidine
    • Einecs: 203-584-7
    • Mininmum Order: 1 g
    • Factroy Site: Yudu County, Ganzhou, Jiangxi, China
    • Price Inquiry: admin@ascent-chem.com
    • Manufacturer: Ascent Petrochem Holdings Co., Limited
    • CONTACT NOW
    Specifications

    HS Code

    473750

    Iupac Name 3-methylaniline
    Chemical Formula C7H9N
    Molar Mass 107.15 g/mol
    Cas Number 108-44-1
    Appearance Colorless to pale yellow liquid
    Density 1.008 g/cm³
    Melting Point -26.3 °C
    Boiling Point 203 °C
    Solubility In Water Slightly soluble
    Flash Point 86 °C
    Pka 4.26 (for the ammonium ion)
    Odor Aromatic, aniline-like

    As an accredited 3-Methylaniline factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing A 500 mL amber glass bottle labeled “3-Methylaniline, ≥99%,” features hazard symbols, product code, batch number, and safety information.
    Shipping 3-Methylaniline should be shipped in tightly sealed, clearly labeled containers, compatible with its chemical nature. It must be transported as a hazardous material, in accordance with international regulations (e.g., DOT, IATA, IMDG). Proper ventilation, protection from heat and incompatible substances, and appropriate documentation are essential during shipping to ensure safety and compliance.
    Storage 3-Methylaniline should be stored in a cool, dry, and well-ventilated area away from sources of ignition, heat, and direct sunlight. Keep the container tightly closed and store separately from oxidizing agents, acids, and alkalis. Use appropriate chemical-resistant containers, and ensure spill containment is in place. Regularly check for leaks and label storage containers clearly.
    Application of 3-Methylaniline

    Applications of 3-Methylaniline in Industrial Manufacturing

    3-Methylaniline, also known as meta-toluidine, serves as a critical intermediate in various chemical manufacturing sectors. The applications below provide a detailed overview of its integration into downstream production, addressing compliance requirements, technical ratios, processing methods, and the typical final products generated in each industry.

    1. Agrochemical Synthesis: Herbicide and Pesticide Intermediates

    Producers of herbicides and selective pesticides incorporate 3-Methylaniline mainly for synthesizing active ingredients such as phenoxy acid derivatives and acylanilide compounds. Manufacturers use this material in the acylation and coupling steps to form the aniline segment of the pesticide molecule. Compliance with safety handling and impurities is critical, especially for export-oriented production lines. Final herbicides require strict monitoring of residual intermediates according to region-specific agrochemical directives and environment-focused frameworks.

    Industry compliance standards

    • EU Regulation (EC) No 1107/2009 (Plant Protection Products)
    • US EPA FIFRA (Federal Insecticide, Fungicide, and Rodenticide Act)
    • China GB 2763 (Maximum Residue Limits for Pesticides in Food)
    • REACH Annex XVII (Substances of Very High Concern)

    Typical usage ratio

    • Ranged at 3–12% by mass in the synthesis step, adjusted based on target compound structure and yield optimization

    Downstream process integration

    • Batchwise feeding to the condensation or acylation reactor after solution-phase dissolution and pre-mixing
    • Inline purification of the post-reaction mixture to remove unreacted raw material

    Final product types

    • 2,4-D analogues (selective herbicides)
    • Alachlor, Metolachlor (pre-emergents)
    • Certain sulfonylurea compounds
    • Other custom aniline-based pesticide actives

    2. Dye and Pigment Intermediate Manufacturing

    Dye and pigment manufacturers use 3-Methylaniline in azo dye synthesis for textile, leather, and pigment dispersions. Diazo coupling reactions employ this raw material to generate chromophores with high resistance to light and chemicals. The purity and isomer content of the starting material determine final color properties and must meet internal specifications for migration and stability, especially for export to regulated textile and food-contact application markets.

    Industry compliance standards

    • OEKO-TEX® Standard 100 (Textile Testing)
    • China GB/T 7573 (Textiles— Determination of pH of aqueous extract)
    • EU REACH Annex XVII (Azo dyes regulation)
    • EN 71-3 (Safety of Toys—Migration of certain elements)

    Typical usage ratio

    • Traditionally 5–16% as the aniline component, modulated to tune hue intensity and fastness parameters

    Downstream process integration

    • Added to the diazotization or coupling kettle following controlled pH adjustment
    • Filtered directly into pigment-formulation blending stages

    Final product types

    • Azo reactive dyes for cotton
    • Solvent dyes for plastics
    • Red and orange pigment dispersions
    • Textile and leather color concentrates

    3. Pharmaceutical Intermediate for API Synthesis

    Pharmaceutical manufacturers select 3-Methylaniline as a building block in the synthesis of key active pharmaceutical ingredients (APIs) such as toluidine-based antihistamines and antitubercular drugs. High analytical purity, controlled metal impurities, and documentation for USP or EP monographs are required. The intermediate stage involves coupling via amide or carbamate linkages, after which extensive purification ensures finished APIs meet pharmacopeial standards for dosage forms.

    Industry compliance standards

    • ICH Q7 (Good Manufacturing Practice for Active Pharmaceutical Ingredients)
    • European Pharmacopoeia Monographs
    • US Pharmacopeia (USP)
    • WHO GMP Certification for APIs

    Typical usage ratio

    • Altogether 7–20% as start material, dependent on targeted molecular synthesis route and yield efficiency

    Downstream process integration

    • Charged to the initial amination or nucleophilic substitution reactor
    • Carried through intermediate crystallization and filtration prior to final API coupling

    Final product types

    • Procaine derivatives
    • Toluidine-class antihistamines
    • Isoniazid analogues for tuberculosis treatment
    • Specialty investigational drug substances

    4. Rubber Chemical & Vulcanization Accelerator Production

    Producers of rubber chemicals use 3-Methylaniline chiefly in the formulation of vulcanization accelerators, particularly those in the thiazole and sulfenamide classes. Accurate dosing at mixing stages assures no carryover of amine impurities, which is critical for technical rubber goods and automotive supply chains. Batch origin traceability and compliance with region-specific chemical safety certifications are mandatory for export and automotive OEM segments.

    Industry compliance standards

    • ISO 9001:2015 (Quality Management System—Chemical Manufacturing)
    • Automotive Industry Quality Standards (IATF 16949)
    • EU REACH Registration—Rubber Sector
    • China GB 21861-2008 (Restriction of Hazardous Substances for Automobile Manufacturing)

    Typical usage ratio

    • 5–10% as an intermediate precursor, calculated relative to total accelerator batch size

    Downstream process integration

    • Melt-phase or solvent dispersion into accelerator synthesis vessel
    • Sequential addition after completion of base rubber mastication

    Final product types

    • 2-Mercaptobenzothiazole (MBT) derivatives
    • Sulfenamide class accelerators (e.g., CBS, TBBS forms)
    • Engineering-grade tire compounds
    • Automotive and conveyor belt vulcanization systems

    5. Specialty Resin and Epoxy Hardener Synthesis

    Specialty chemical manufacturers utilize 3-Methylaniline in the creation of epoxy resin curing agents, often for electronics encapsulation and high-durability coatings. The amine structure imparts controlled reactivity and improved glass transition temperatures in the final crosslinked polymer. Handling procedures follow occupational safety checks due to potential byproduct amines, while technical specifications address low-halogen content for electronic grade resin systems.

    Industry compliance standards

    • UL 94 (Flammability Standard for Plastics Used In Devices and Appliances)
    • RoHS Directive 2011/65/EU (Restriction of Hazardous Substances)
    • China SJ/T 11363-2006 (Requirements for Concentration Limits for Certain Hazardous Substances in Electronic Information Products)
    • EN 14582 (Halogen content testing in electronics)

    Typical usage ratio

    • Blended at 4–9% of total amine hardener mix, tuned for desired final curing kinetics and electrical insulation resistance

    Downstream process integration

    • Dosed to mixing reactors following prepolymer stage or added during hardener compounding
    • Filtration to remove insolubles before final packaging

    Final product types

    • Amine-terminated curing agents for epoxy systems
    • Two-pack industrial floor and anticorrosion coatings
    • Electronic encapsulant base resins
    • Industrial adhesives and sealants with enhanced thermal performance

    Free Quote

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    Certification & Compliance
    More Introduction

    3-Methylaniline: Reliability from the Source

    Introducing 3-Methylaniline: The Craftsman’s Perspective

    Coming from years spent in the thick of the chemical industry, I’ve learned there’s no substitute for knowing your products at a granular level. 3-Methylaniline, often called meta-toluidine in the plant, carves out its own place with a consistency you can rely on and a profile that suits demanding applications. Each batch comes out of reactors that have seen more than a few formulation tweaks over their working lives. The process has seen steady refinement: temperature controls razor-sharp, raw materials sourced cleaner, and downstream purification steps that cut out byproducts often missed by less specialized operators.

    You get a light yellow to brown oily liquid with a distinct amine odor, a fingerprint that lingers in any facility where aromatic amines form an essential backbone. The melting point and boiling point are steady across runs—a sign of the handling care and purity checks along each turn. We don’t hide behind broad purity claims; GC traces get scanned batch by batch, with experienced eyes looking for spikes where they shouldn’t be. End-users in dyes, pigment synthesis, and pharmaceuticals bring us their technical questions all the time. The honest approach works for both sides—no skating by with “industry standard” as a shield.

    The Role of 3-Methylaniline in Industrial Applications

    Every molecule produced finds its way into a process designed around reliability. Dye and pigment synthesis keeps calling for 3-Methylaniline because its methyl group at the meta position opens up specific color and fastness profiles. Clients who run azo dye plants see how the substitution pattern pushes properties hard to match with ortho- or para-toluidine. In rubber antioxidant lines, its reactivity with nitrosating agents comes into play. Some pharmaceutical intermediates would simply stall out without a supply of clean, high-assay meta-toluidine, and that means the practical difference between an ideal spec and a slight contaminant often comes down to how you run your columns and separations.

    Most customers have specialized technical teams. Still, some operations, especially smaller or medium-scale manufacturers, trust our advice on downstream compatibility. Solubility in most common organic solvents—like ethanol, ether, and benzene—lends flexibility in their plant setups. No one can afford a sticky residue or emulsion when scaling up a reaction, so clarity on these physical characteristics comes straight from our production team, not from an old encyclopedia reference.

    Model and Control Across Production Batches

    Our model of 3-Methylaniline isn’t based on branding but on how the production process has matured through operational transparency. Every adjustment in feedstock or distillation shows in the chromatogram, and a little slip-up propagates downstream faster than some would expect. Our focus has always been tight control of core specifications: purity above 99%, controlled isomer content, and minimum trace aniline, water, or nitro compounds. Each process operator learns quickly what happens if column temperatures drift, or if incoming aniline isn’t as clean as promised. That real-world experience translates into instruction and oversight that prevents minor deviations from snowballing.

    Compared to less-refined sources, you’ll see consistent color and viscosity from drum to drum, which matters more with each scale-up. On-site storage recommendations aren’t the same across climates. Some customers work in warm, damp coastal outfits; others operate high-altitude inland plants—keeping 3-Methylaniline stable means different protocols for each, and we’re upfront about best practices, based not only on best guesses but on real feedback from customer runs gone right—and wrong.

    Making the Difference: Beyond Commodity Chemicals

    3-Methylaniline gets lumped in with other toluidine isomers by newcomers, but the proof shows in synthesis yields and purity benchmarks. Comparisons come up most often with ortho- and para-toluidine, since all three share the same C7H9N formula, but their reactivity and selectivity make worlds of difference. The meta isomer slots into aromatic substitution reactions at intervals the others can’t match, especially in making certain azo pigments and intermediates for agricultural chemicals and active pharmaceutical ingredients.

    Experience shows that shuffling isomers between processes might save pennies, but the real price comes out in waste and off-spec product. We’ve seen customers switch from cut-rate meta-toluidine only to find clogging in their dye reactors or inconsistent crystal formation in pigment synthesis. There’s no quick fix for a batch ruined at the molecular level. That’s why controlling side isomers and impurity bleed at our plant is always front of mind.

    Ratcheting Up Purity: Customer-Driven Demands

    Requests for higher assay levels and tighter impurity specs roll in as customer plants refine their expectations. Each sector brings new demands. Dye and pigment makers tire of having to carry out additional purification when a little more attention upstream could solve the problem. Pharmaceutical manufacturers enforce limits on aniline and nitrotoluene traces—a single blip throws an entire run out of FDA compliance.

    Most customers trace a problem to its source fast. QA labs catch peaks in chromatograms most never see, so we rely on their vigilance as a backstop; but the routine checks, long experience, and calibration standards we maintain upstream mean trouble doesn’t travel far. People on our line have handled more than a few crisis calls, and real solutions draw from data, not wishful thinking.

    Meeting the Evolving Needs of the Chemical Industry

    Innovation in end-user sectors—especially specialty dyes and high-performance polymers—raises questions on what tweaks can be made without rocking process stability. We work closely with customers trying new routes or testing modified catalyst loads, and feed them data on how 3-Methylaniline behaves when pushed outside the norms. You can’t match that kind of feedback loop buying from an anonymous supplier; you need the producer’s track record and willingness to share lessons from past missteps. Adjusting methyl group positioning or working to suppress certain isomeric forms matters because plant margins depend on not recycling or tossing bad runs.

    We see more joint R&D every year, and our plant-side chemists work shoulder to shoulder with external teams. Chemical engineers know that product isn’t just a bottle of liquid, but a complex recipe unfolding across equipment and people. Every process tweak on our end filters into customer optimization, and converse feedback keeps both sides dialed in. That real partnership separates a working supply chain from a transactional sale.

    Environmental Care and Regulatory Insight—On the Ground

    Handling aromatic amines safely is a chunk of our plant’s daily reality. Every worker comes in understanding exposure risks—engineering controls, PPE, and strict spill protocols. On the environmental front, we’ve adopted closed-loop vapor recovery and solvent reclamation solutions. Years back, local inspectors gave us direct feedback about improvements needed in our waste treatment. That critical feedback led us to install new stripping columns and invest in continuous monitoring. We know how small leaks or vent stack excursions can stack up against community relations and regulatory goodwill.

    Nothing beats on-the-job experience: operators double-checking line connections before each shift, tank farm techs scrubbing vapor heads, and QA staff correlating batch logs with instrument readings. The regulatory framework gets more complex each year—REACH, EPA, and regional standards demand deeper documentation on provenance and impurity levels. Any claims on safety, sustainability, or product compliance come from direct audit trails, not empty marketing lines.

    Refining Hands-On Solutions for Handling and Shipping

    Bulk shipments head to plants using 3-Methylaniline in both closed and open systems. We’ve fielded the full range of shipping and storage challenges: resin-lined drums for longer routes, nitrogen-blanketed ISO tanks for large users, and guidance on pump and piping compatibility at destination. Years in transport logistics taught us to sweat details—sample vials pulled batchwise, tamper-evident closures, and UN-approved packaging keep quality and safety locked in through every link of the chain.

    Users sometimes ask about freezing or slow crystallization during cold weather transport. We recommend drum warming or gentle agitation based on recorded experiences from winters in northern depots. For customers in hot, humid zones, we’ve consulted on inventory rotation and dehumidified storage—lessons built on actual problems, not theoretical conditions. Each transfer, from our tank to a customer’s bulk line, gets reviewed for residual trace, line clearing, and stack conditioning. These details sound unremarkable until you’ve lost a week’s production to a contaminated pipeline—something many new operators learn once, the hard way.

    Clarifying Differences from Other Aromatic Amines

    Plenty of inquiries come our way about whether 3-Methylaniline can swap in for other aromatic amines, like aniline, ortho-toluidine, or para-toluidine, in downstream synthesis. We tackle the answer honestly: often, you can’t cut corners without paying a price in performance. The methyl group at the 3-position tunes both electron density and reactivity. Key intermediates in dyes and pharmaceutical actives end up structurally distinct due to these subtleties. We’ve witnessed process drift first-hand in plants that tried making do with para isomer to cut costs, only to find final product drifting off-color or failing stability tests.

    In niche polymers and specialized fine chemicals, even minor isomer contamination leads to product haze, off-smell, or unwanted reaction byproducts. We’ve worked directly with analytical labs to trace “mystery” contaminants back to off-spec toluidine, then helped refit plant procedures based on the root cause. Feedback cycles like these sharpen both our understanding and our plant discipline; no process improvement ever lives in a vacuum.

    Practical Problem Solving Based on Experience

    Plant chemistry, at its heart, thrives on repeatable, predictable behavior from raw materials. One missed spec—a little too much water, isomer impurity, or oxidative residue—can create a domino effect through an entire month’s production. Our track record comes from solving these headaches for clients in real time. Once, a pigment operation grinding out tens of tons a week hit clouding and off-batch issues. Their technical lead called us up at 8 p.m., and our crew worked through sample splits and shipment logs overnight. The GC showed just enough ortho isomer off our usual trace baseline, pinpointing the root cause. Instead of endless process-tweaking on their side, we isolated a raw material deviation in our own feed, corrected the supplier issue, and issued a corrected lot. That episode didn’t just salvage a run—it cemented a working relationship built on trust and accountability. These stories happen a dozen times each year. They reinforce every improvement we bake in, every training hour for our plant team, and every update in instrumentation.

    Direct feedback from downstream partners speeds learning on both sides. Some syntheses push 3-Methylaniline to its limits, demanding ultra-low impurity levels or surfactant-grade clarity. We accept those challenges, leaning on incremental improvements: purer feedstocks, more precise temperature ramps, and smarter solvent handling. Each process evolution gets shared with clients aiming to keep their own competitive edge.

    Facing Tough Questions—The Value of Transparency

    Customers don’t just want numbers on a spec sheet—they want stories from the shop floor and a straightforward account of what can go right or wrong. Our open-door policy invites audits, site tours, and detailed breakdowns of every step. Such transparency reassures partners that the product they buy now matches the samples they tested six months earlier. The most rigorous clients visit our lines, digging into batch logs and process narratives until they’re satisfied our word matches our product. We see those visits as opportunities to build a technical partnership rather than just signing off another sale.

    We’ve taken our lumps over the years. Process interlocks sometimes need replacement, or production rates nudge too close to specification limits. That’s the time to fess up, call the customer, and walk through the issues. Every line of trust starts from how open we are about both strengths and reasons for a deviation. Our production notes record not just the target values, but the steps taken, lessons learned, and corrections instituted. We carry that openness through every client relationship.

    3-Methylaniline in Tomorrow’s Chemical Industry

    The push for higher performance intermediates and more sustainable practices never lets up. Customers now request lifecycle impact statements, waste reduction plans, and process carbon accounting. We’re adjusting. While maintaining traditional batch quality, we test solvent-recovery, more efficient reaction pathways, and reduced-waste handling. Our investment in staff development pays off—senior operators mentor new hands on careful material handling, documentation, and customer-focused troubleshooting.

    Some pharmaceutical customers eye higher regulatory bars, especially for trace impurities and heavy metals. That means routine batch analysis gets even more intense. For dye makers facing new REACH requirements, we supply expanded impurity profiles and connect them with our environmental management team. Meeting these moving targets takes more than compliance—it needs a relentless drive to improve, cross-question, and learn from every outcome.

    Innovation means accepting feedback, running joint technical tests with partners, and refining not just product but how it moves from drum to process reactor. Upgrades in automation and sensor control give our staff better tools and customers deeper confidence. Our experience tells us the best way to build lasting partnerships is through shared learning and continuous improvement, giving end-users steady confidence batch after batch.

    Your Partner in Specialty Chemical Excellence

    All the years spent handling 3-Methylaniline—across production, refining, and front-line problem solving—show in every drop that leaves the plant. Our commitment to quality emerges not from slogans but from the routines, the honest mistakes, and the shared challenges with clients across the world. We stand by real-world solutions, continuous learning, and a candid approach to every partnership. Behind every delivery stands a team accountable for what’s inside, true to the principles learned on the plant floor and with every technical call that shapes tomorrow’s chemical solutions.

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