Products

3-Methyl-1-Butanol

    • Product Name: 3-Methyl-1-Butanol
    • Alias: Isoamyl alcohol
    • Einecs: 201-148-0
    • Mininmum Order: 1 g
    • Factroy Site: Yudu County, Ganzhou, Jiangxi, China
    • Price Inquiry: admin@ascent-chem.com
    • Manufacturer: Ascent Petrochem Holdings Co., Limited
    • CONTACT NOW
    Specifications

    HS Code

    128716

    Cas Number 123-51-3
    Molecular Formula C5H12O
    Molar Mass 88.15 g/mol
    Appearance Colorless liquid
    Odor Alcoholic, fusel-like
    Density 0.818 g/cm³ (20 °C)
    Melting Point -117 °C
    Boiling Point 131 °C
    Flash Point 41 °C (closed cup)
    Solubility In Water 14 g/L (20 °C)
    Vapor Pressure 5 mmHg (20 °C)
    Refractive Index n20/D 1.406
    Autoignition Temperature 345 °C

    As an accredited 3-Methyl-1-Butanol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing A 500 mL amber glass bottle labeled "3-Methyl-1-Butanol," with hazard symbols, safety information, and a secure screw cap.
    Shipping 3-Methyl-1-Butanol is typically shipped in sealed containers, such as drums or bottles, to prevent leakage and contamination. It should be handled and transported according to regulations for flammable liquids. Proper labeling, ventilation, and protection from heat sources are essential during shipping to ensure safety and compliance with hazardous material guidelines.
    Storage 3-Methyl-1-butanol should be stored in a tightly closed container in a cool, dry, well-ventilated area away from sources of ignition, heat, and incompatible substances such as strong oxidizers. Protect from direct sunlight and moisture. Ensure proper grounding and bonding if transferring large quantities. Store away from food and drink, and label containers clearly to prevent accidental misuse.
    Application of 3-Methyl-1-Butanol

    Applications of 3-Methyl-1-Butanol in Industrial Manufacturing

    As a direct manufacturer specializing in high-quality 3-Methyl-1-Butanol, we serve industrial clients engaged in diverse yet well-defined downstream sectors. The following application scenarios illustrate the specific integration pathways, compliance standards, formulation guides, and end product categories where our raw material plays a crucial process role within real-world production environments.

    1. Flavor and Fragrance Ester Synthesis

    3-Methyl-1-Butanol functions as a key precursor in the production of fruity and floral esters, particularly in flavor and fragrance formulations. It undergoes esterification reactions with organic acids such as acetic acid or formic acid to yield acetate or formate esters, which impart recognizable notes to food flavors, personal care scents, and perfumery bases. This high-purity branched alcohol allows formulation chemists to achieve consistent sensory profiles while meeting international food and cosmetic standards.

    Industry compliance standards

    • Food Chemicals Codex (FCC)
    • EU Regulation (EC) No 1334/2008 on Flavourings
    • IFRA Standards for Fragrance Ingredients
    • Japanese Food Sanitation Law – Standards for Use of Additives

    Typical usage ratio

    • 0.2–0.8% (w/w) as a reactant in ester synthesis; actual dosage adjusted based on target ester structure and regulatory threshold for flavor constituents

    Downstream process integration

    • Direct addition to batch or continuous reactors during catalytic esterification; incorporates at the step where alcohol and organic acid combine under controlled temperature and pressure conditions

    Final product types

    • Ethyl isovalerate aroma esters (fruity flavors)
    • Isoamyl acetate (banana, pear notes for food and beverage)
    • Complex perfumery bases for soaps and detergents
    • Toiletry fragrances used in shampoos, lotions, and deodorants

    2. Pharmaceutical Intermediate Synthesis

    Pharmaceutical manufacturers rely on 3-Methyl-1-Butanol as a building block during multi-step synthesis of active pharmaceutical ingredients (APIs). It serves as a reactant in the construction of isopentyl side chains and is also employed as a protective group or extraction solvent in heterocyclic and aliphatic drug production. Its purity level must comply with strict pharmacopeial standards to prevent contamination of downstream pharmaceuticals including anti-infectives and cardiovascular agents.

    Industry compliance standards

    • USP–NF (United States Pharmacopeia – National Formulary) monograph regulations for pharmaceutical excipients
    • ICH Q7 Good Manufacturing Practice for APIs
    • European Pharmacopoeia 10.0 (Ph. Eur.)
    • China Pharmacopoeia for excipient and raw material control

    Typical usage ratio

    • 0.5–5% (molar equivalent) per reaction step, varying with molecular design and scale-up requirements

    Downstream process integration

    • Incorporated during nucleophilic substitution, esterification, or as a phase-transfer medium within GMP synthesis suites; enters at stages where isopentyl fragments or alcohol groups are introduced

    Final product types

    • Isopentyl-derivative pharmaceutical intermediates
    • API precursors including penicillin esters
    • Bulk agents for antihypertensive and anti-inflammatory drugs
    • Solubilizing agents in parenteral preparations

    3. Solvent and Extraction Agent in Fine Chemical Synthesis

    Chemical synthesis operations depend on 3-Methyl-1-Butanol for its selective solubility and low volatility. It is incorporated into reaction media to enhance the extraction of polar and non-polar intermediates, as well as in crystallization and separation of fine chemicals, dyes, and agrochemical actives. Its physicochemical profile provides clear partitioning for multi-phase reactions and supports recovery efficiency in plant-scale operations that must comply with solvent residue limits for chemical specialties.

    Industry compliance standards

    • REACH Regulation (EC) No 1907/2006 for industrial chemicals
    • OECD Guidelines for Testing of Chemicals (solvent use in synthesis)
    • National Standard of the P.R.C. for industrial solvent use
    • ISO 9001 Quality Management for chemical processing

    Typical usage ratio

    • 5–20% (v/v) relative to total solvent phase; exact volume calculated by solubility parameter and desired partition coefficient

    Downstream process integration

    • Introduced during initial dissolution or extraction phases in stirred-tank or flow reactors; retained or distilled in solvent recovery units post-synthesis

    Final product types

    • Colorant intermediates
    • Agrochemical precursors
    • Photographic chemicals
    • Specialty process auxiliaries

    4. Lubricant and Hydraulic Fluid Additive

    Leading lubricant formulators add 3-Methyl-1-Butanol as a minor component to enhance solubility of anti-wear agents and optimize the pour point of specialty oils and synthetic hydraulic fluids. Its controlled volatility and branched structure reduce foaming and improve performance in precision lubrication systems, including high-speed machinery and aviation hydraulic circuits, while adhering to national and international technical standards for base oils and lubricant additives.

    Industry compliance standards

    • ASTM D6079 Standard Test Method for Evaluating Lubricity
    • DIN 51502 Classification of Lubricants
    • ISO 6743 Lubricant Classification System
    • API 1509 Engine Oil Licensing & Certification System

    Typical usage ratio

    • 0.1–1.2% (by total base fluid weight); level adjusted based on required solubility enhancement and pour point modification

    Downstream process integration

    • Added post-refining during base stock blending or formulated in-line before package dosing of additives; quality checked in finished fluid blending tanks

    Final product types

    • Low-temperature hydraulic fluids
    • All-season gear oils
    • Multipurpose greases for industrial machinery
    • High-performance turbine and compressor oils

    5. Antifoam Formulations for Industrial Processing

    3-Methyl-1-Butanol serves as an efficient antifoam booster in water-based and oil-based defoaming agents produced for the pulp & paper, fermentation, and wastewater treatment industries. Its strong spreadability and low surface tension enable rapid foam collapse during high-shear mixing, aerobic processing, or biological aeration steps. Each finished antifoam concentrate must comply with industry-specific regulations regarding process additives and functional excipient levels.

    Industry compliance standards

    • FDA 21 CFR 173.340 – Defoaming Agents Permitted in Food Processing
    • OECD Ecolabel Criteria for Process Chemicals
    • EN 14088 – Antifoaming Agents for Industrial Applications
    • China GB 30616-2014 for permitted antifoam agents

    Typical usage ratio

    • 0.2–2.0% (w/w) in commercial antifoam agent formulations; dosage tuned to process conditions and residual limits

    Downstream process integration

    • Incorporated into silicone or mineral oil carriers during compound blending; dosed into industrial process streams at continuous or batch dosing points

    Final product types

    • Pulp & paper process antifoams
    • Fermentation vessel defoamers
    • Textile scouring antifoam agents
    • Municipal and industrial wastewater process additives

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    Certification & Compliance
    More Introduction

    3-Methyl-1-Butanol: A Product Rooted in Real-World Chemical Manufacturing

    Real Experience Shaping Our Approach

    On our factory floor, 3-Methyl-1-Butanol isn’t some exotic molecule found in textbooks. It’s a reliable, familiar compound that keeps operations moving in an incredibly practical way. We manufacture this alcohol with a focus on consistency and safety, not simply because a certificate requires it, but because our customers depend on results for their day-to-day processes. Our people have spent years refining methods to ensure that each drum or tanker we ship meets the requirements set by decades of chemical engineering, customer application feedback, and rigorous lab analysis.

    Understanding 3-Methyl-1-Butanol: Physical Properties and Specifications

    3-Methyl-1-Butanol falls into the family of amyl alcohols, and its structure makes it distinct. Chemists sometimes call it isoamyl alcohol, but regardless of the name, the product walks a line between volatility and utility. With a boiling point of about 131°C and a moderate vapor pressure, it’s neither excessively volatile nor stubborn to process. A typical batch leaves our facility clear and colorless, with a faintly fruity aroma that sometimes surprises visitors stepping onto the filling line.

    Specifications matter for anyone who works with 3-Methyl-1-Butanol. Customers check every barrel for purity, water content, and acid value because their downstream applications depend on reliability. Our typical product purity sits above 99 percent, which meets the requirements of many processes in flavor and fragrance engineering, solvents, and even as a biochemistry reference compound. Low water content speaks to good separation and storage practices — we use closed systems and protective blankets for every transport vessel. Standard practice is to confirm density, refractive index, and a handful of impurity markers, all checked with honest lab records for traceability.

    Everyday Usage and Real-World Needs

    We see 3-Methyl-1-Butanol moving through several different sectors. Its most visible use lies in producing esters for flavor and fragrance houses. These companies order 3-Methyl-1-Butanol to react with acids, forming fruity-smelling esters used not just in food or beverages, but in perfumes and industrial masking agents. Whenever the product is destined for aroma chemicals, batches are monitored even more closely for traces of other amyl alcohols or unwanted byproducts. Customers send personnel to our facility for sample draws right from processing tanks, demanding documentation and hands-on transparency.

    Solvent use forms another major segment. Laboratories and industrial plants alike use 3-Methyl-1-Butanol as a medium for reactions that need a balance between solvency and low reactivity. It dissolves organic compounds that refuse to behave in either water or lighter alcohols. Paints and coatings formulators ask for it to modify flow or drying properties, making sure the alcohol won’t yellow or alter final appearance. We routinely field technical questions about solubility, compatibility, and the effects of trace moisture on sensitive catalyst systems. The feedback loops from these customers continue to shape our production and QA practices year after year.

    Biochemistry labs value 3-Methyl-1-Butanol for specific extraction and separation techniques. Among the classic uses: isolating RNA from tissue samples. Precision matters in these critical steps, because stray impurities or low purity affects yields and reproducibility. Years ago, we worked with research facilities to fine-tune purification steps, limiting aldehyde content and other oxidizable traces for this end market. Their confidence in the product comes from repeated lot-to-lot reliability, not marketing promises.

    In fuel technology, 3-Methyl-1-Butanol stands out from other amyl alcohols for its balance of energy density and compatibility. Experimental blends for advanced combustion engines or bio-based fuel alternatives emerge now and then, and engineers often want detailed certificate of analysis records for each trial. These customers push us to document every lot with a level of detail rivaling food or pharma supply chains. They ask about corrosion, material compatibility, seasonal temperature stability — and our technical staff keeps documentation on hand stretching back years to verify data, show trends, and spot opportunities to improve.

    The Difference: Not All Amyl Alcohols Are the Same

    Some products masquerade as interchangeable, but subtle differences in branching matter immensely in industrial practice. The distinction between 3-Methyl-1-Butanol and its sibling n-Amyl alcohol (1-Pentanol) looks trivial on paper but changes the physical and chemical properties that users care about. 3-Methyl-1-Butanol’s extra methyl group shortens hydrogen bonding distance, slightly raising its boiling point and lowering polarity. This adjustment alters how it dissolves resins or esters, how fast it evaporates in open air, and how it behaves in closed systems with temperature variations.

    Customers running large reactors can see the difference in mixing and emulsion stability. Paint plants notice shifts in flow-out and curing times when substituting one type for another. Flavor firms chase purity and isomer distribution, because the wrong isomer throws off both aroma and regulatory files. We’ve fielded calls from partners who unwittingly swapped to a mixture of amyl alcohols from commodity traders, only to see their results drift, odor profiles shift, or quality certifications threatened. Our business, shaped by decades of technical partnerships, makes clean separation and documentation of isoamyl alcohols a core part of production.

    There’s also a regulatory angle. Different amyl alcohols carry different food additive registrations, toxicology profiles, and shipping restrictions. 3-Methyl-1-Butanol has approvals in some food and flavor codices that its siblings lack, but export markets can shift rules without warning. Our regulatory staff spends time monitoring global updates, checking new monographs, and responding directly to field queries from inspectors and compliance officers. This attention reduces headaches during end-use registration or customs clearance.

    Safety, Handling, and Direct Experience in Plant Settings

    The desk-to-drum journey for any chemical means nothing if safety doesn’t support every step. 3-Methyl-1-Butanol behaves as a flammable liquid, with a flash point in the mid-40s Celsius. Field workers know the scent, the slight slickness on pipelines, and potential for static generation during transfer. Our team runs containment and fire suppression checks before every transfer. These measures stem from real incidents at other plants: pooling beneath leaky connections, pumps driven too fast, or grounding straps overlooked during busy shift changes.

    Production staff watch for dermal exposure and inhalation risk. Proper gloves, splash goggles, and local exhaust aren’t rote requirements for us — they keep the engineering teams focused on batches, not clinic visits. Close communication with customer EHS departments often improves our own hazard controls. Last year, a client in adhesives asked for a revised methods statement after their operators reported irritation from cleaning procedures. Adopting their feedback improved our own training, and we included new warnings in our documentation, not because standards shifted, but because a partner’s direct feedback unearthed a blind spot.

    Storage, Transport, and Quality Assurance from Start to Finish

    Bulk containers for 3-Methyl-1-Butanol stay under nitrogen or blanketed air. This avoids oxidative breakdown, which affects odor and shelf life, especially for aroma end-users. Temperature control matters — the alcohol can turn cloudy as temperatures dip, which reflects only precipitation, not impurity, but bulk users want clarity for their own transfer pumps and visual QA. Tank inspections, lining specifications, and cleaning procedures all return in customer audits. Our plant management team welcomes these checks because each one either confirms good controls or reveals an opportunity to do better.

    Quality doesn’t end at the filling nozzle. We send samples to outside labs — not just for routine confirmation, but for stress tests (accelerated aging, freeze-thaw cycling, and skin-surface residue simulation) that matter to actual plant users. Results feed back into our process control dashboard, not just into marketing brochures. This open-book approach reassures customers and also sharpens our ability to troubleshoot when tanks arrive out of spec.

    Flexibility in packaging rounds out our supply model. Some clients work exclusively with large tankers for continuous operations, others request intermediate bulk containers, and a niche group wants small drums for pilot and research work. We use dedicated lines for each format, cleaning and testing not because checklists say so but because we know trace residues present real-world risks for stringent end-use applications. Failure to follow through means lost trust and repeat business slipping away — something we never take for granted.

    Regulatory Shifts and Customer Demands: Staying Current in a Moving Landscape

    The global chemical market doesn’t sit still. What counted as food grade last year may face a new purity cut-off tomorrow. We work with both long-arc regulatory programs and short-term customer requirements. Certifying 3-Methyl-1-Butanol for use in food contact, for EU REACH, or for kosher/halal audits isn’t a one-time task. Each claim stands on a base of real lab data, traceable batches, change controls, and sometimes, third-party audits walking our warehouse aisles and questioning our shop floor staff.

    A shift in a fragrance regulation or the classification of a minor impurity can ripple through dozens of customer specifications. Last year, an unexpected update to a region’s list of regulated flavor ingredients forced an immediate review of all shipping documentation for several finished lots. We handled the situation by cross-checking every test record and kept customers in the loop as we re-certified product for upcoming imports. Experience here counts for more than promises: knowing which regulatory changes tend to stick and which remain proposals, how to work with compliance agencies, and how to communicate technical detail to non-chemist procurement managers all combine to build long-term trust.

    Environmental Responsibility in 3-Methyl-1-Butanol Production

    Chemical manufacturing produces impact as well as value. Traditional syntheses of 3-Methyl-1-Butanol draw on petrochemical feedstocks, but we’ve fielded growing questions about biobased sourcing. A few distillation facilities now capture isoamyl alcohols as co-products from fermentation and bioethanol operations, but scaling these to commercial tonnage presents logistical and cost challenges. Still, a number of our customers want documentation to show renewable sourcing, carbon intensity scores, or detailed life cycle assessment data.

    We have taken steps to pilot biobased supply, testing feedstock for trace markers and running system flushes before introducing into regular inventory. Differences in minor contaminant profiles present hurdles — bio-based streams can differ significantly in residual fusel oils, aldehyde carry-over, or even color. Sharing these details plainly with customers leads to honest dialogue about specification targets, and new certification pathways for customers focused on green chemistry initiatives.

    Emissions control, waste minimization, and responsible water handling remain critical. Scrubbers on venting lines pull down fugitive alcohols, and wastewaters get pretreated on-site. Engineers track solid-phase residue and optimize steam stripping schedules when production shifts between isoamyl and other alcohols. These efforts center less on regulatory minimums and more on confidence — knowing neighbors, local officials, and downstream customers would accept a tour of operations and see the real standards applied.

    Customer Relationships and Ongoing Collaboration

    Technical support for 3-Methyl-1-Butanol doesn’t finish at the sales order. Many collaborations span years, and shared trials in customer plants lead to improvements we incorporate back into our protocols. A coating plant in Asia once reported issues with haze and slow dry time after switching to our material. Reviewing batch data, we traced the source to a subtle rise in trace hexanol carry-over, tightened fractionation windows, and followed up with documented improvements — not just an apology or a price credit.

    We track how customer engineers actually use the product day by day. Some run automated reactors with real-time monitoring, others use simple batch methods with robust operator oversight. What matters is clear feedback and fast troubleshooting. We set up direct lines from process engineering to customer tech teams, bypassing sales when technical details drive the issue. This arrangement accelerates joint troubleshooting, helps both sides understand constraints and workarounds, and prevents finger-pointing when process upsets occur.

    Why Our Perspective Matters

    Our role as manufacturer runs deeper than batch numbers on a drum. Every specification, adjustment, or new packaging approach carries the weight of actual process experience. If isoamyl alcohols seem interchangeable on paper, the lived reality of customers and plant staff tells a sharper story: chemical structure, purity, and handling each leave visible marks on process yields, safety outcomes, and supply chain resilience.

    We don’t see ourselves as the sole authority. Years of continuous process improvement have shown us that real progress depends on listening, adapting, and learning from those who handle, transform, and add value to 3-Methyl-1-Butanol every day. The most rigorous quality record cannot substitute for the flow of real experience, technical diligence, and openness to critique. These priorities shape everything we do — from first batch to final shipment.

    Conclusion: A Commitment Beyond Compliance

    Cutting corners, making swap-outs, or tolerating lapses in purity may seem tempting in a commodity-driven landscape. Our experience says otherwise. With every shipment of 3-Methyl-1-Butanol, we deliver more than a chemical. We provide reliability built on standards shaped by feedback from engineers, regulatory staff, and everyone who trusts their finished product to our hands-on quality. Feedback challenges us to improve, and we meet those challenges face-on because in our business, trust and track record aren't optional — they’re what keep us coming back to do the work, day in and day out.

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