3-Ethoxyaniline

    • Product Name: 3-Ethoxyaniline
    • Alias: m-Anisidine
    • Einecs: 211-470-5
    • Mininmum Order: 1 g
    • Factroy Site: Yudu County, Ganzhou, Jiangxi, China
    • Price Inquiry: admin@ascent-chem.com
    • Manufacturer: Ascent Petrochem Holdings Co., Limited
    • CONTACT NOW
    Specifications

    HS Code

    449231

    Chemical Name 3-Ethoxyaniline
    Synonyms m-Ethoxyaniline
    Molecular Formula C8H11NO
    Molar Mass 137.18 g/mol
    Cas Number 536-90-3
    Appearance Colorless to pale yellow liquid
    Boiling Point 241-243 °C
    Melting Point -10 °C
    Density 1.06 g/cm³
    Refractive Index 1.573
    Solubility In Water Slightly soluble
    Flash Point 116 °C
    Smiles CCOC1=CC=CC(N)=C1

    As an accredited 3-Ethoxyaniline factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 500g of 3-Ethoxyaniline is supplied in a sealed amber glass bottle with a secure screw cap and clear hazard labeling.
    Shipping 3-Ethoxyaniline should be shipped in tightly sealed containers, protected from light, heat, and moisture. It must be labeled as a hazardous chemical and transported in accordance with local, national, and international regulations. Use appropriate cushioning and secondary containment to prevent leaks during transit, and ensure compatibility with packaging materials.
    Storage 3-Ethoxyaniline should be stored in a tightly sealed container, away from sources of ignition, direct sunlight, and moisture. Keep it in a cool, dry, and well-ventilated area, isolated from incompatible substances such as strong oxidizing agents and acids. Properly label the container and ensure appropriate safety measures, including secondary containment and spill containment materials, are readily available.
    Application of 3-Ethoxyaniline

    Applications of 3-Ethoxyaniline in Industrial Manufacturing

    As a direct manufacturer, we supply 3-Ethoxyaniline with consistent quality and process transparency, supporting multiple specialized downstream manufacturing sectors. Our expertise ensures a reliable supply chain for end-use applications that demand strict regulatory adherence, precise formulation control, and thorough integration into customer production systems. Below we outline the established industrial application scenarios where this intermediate drives both innovation and process consistency.

    1. Synthesis of Azo Dyes for Textile and Leather Processing

    In the colorant industry, 3-Ethoxyaniline serves as a diazo component for the controlled manufacture of certain yellow and orange azo dyes. Reactive dye producers utilize its ethoxy functional group to develop color shades with targeted fastness and solubility properties, ensuring that dyed fibers meet durability and safety requirements for garments, home textiles, and leather goods. Our material integrates into the core synthesis stage, influencing final color strength and tone consistency batch-to-batch.

    Industry compliance standards

    • OEKO-TEX® Standard 100
    • ZDHC MRSL (Zero Discharge of Hazardous Chemicals)
    • REACH Regulation (EC) No 1907/2006
    • EN ISO 105 Series for color fastness testing

    Typical usage ratio

    • 10–20% relative to total primary amine content in azo dye coupling formulations; adjustment based on shade intensity and downstream fiber compatibility

    Downstream process integration

    • Introduced at the aromatic amine diazotization stage prior to coupling with naphthol or other coupling agents
    • Monitored for residual content as part of effluent and waste stream purification

    Final product types

    • Sulfonated azo dyes for cotton fabrics
    • Dispersed azo dyes for polyester textiles
    • Direct dyes for leather finishing
    • Stable pigment preparations for industrial ink formulations

    2. Pharmaceutical Intermediates for Active Ingredient Synthesis

    Innovator and generic pharmaceutical companies rely on 3-Ethoxyaniline as a key intermediate in custom syntheses for API side-chain modification and heterocyclic ring construction. Its controlled reactivity and purity allow precise progression in multi-step processes, including the manufacture of specific anti-inflammatory agents and antihypertensive drugs. Proper documentation and traceability in every batch ensure robust support for customer regulatory filings.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice for Active Pharmaceutical Ingredients
    • USP/NF Monographs (as applicable for downstream APIs)
    • EudraLex Volume 4 – GMP Guidelines
    • 21 CFR Parts 210 and 211 (cGMP for Finished Pharmaceuticals)

    Typical usage ratio

    • Stoichiometric quantities as dictated by the target API pathway, commonly 1.0–1.2 equivalents per reaction step involving aromatic amination

    Downstream process integration

    • Fed into condensation or cyclization stages after initial raw material purification
    • Subject to in-process controls for impurity profiling prior to API isolation

    Final product types

    • NCE intermediates for anti-inflammatory drugs
    • Precursor units for antihypertensive or CNS-active APIs
    • Building blocks for custom CRO/CDMO synthesis contracts
    • Complex heteroaromatic ring systems in specialty pharma research

    3. Agrochemical Building Blocks for Herbicide and Fungicide Synthesis

    Major agrochemical formulators utilize 3-Ethoxyaniline for introducing ethoxy-substituted aniline moieties in the synthesis of both selective herbicides and systemic fungicides. Its consistent reactivity supports the high-throughput environment of agricultural intermediate production, with careful management of by-product formation and adherence to environmental regulations. Producers benefit from reproducible input quality, influencing final bioactivity and selectivity against target species.

    Industry compliance standards

    • FAO/WHO Guidelines for pesticide specifications (JMPS)
    • EU Regulation (EC) No 1107/2009 on plant protection products
    • ISO 9001 for Quality Management Systems in agrochemical production
    • GLP (Good Laboratory Practice) for ecological and residue analysis

    Typical usage ratio

    • 5–15% of total aniline derivatives in multi-component synthetic routes; proportion customized based on molecular target's required functional group density

    Downstream process integration

    • Dosed during initial aromatic amination or amidation reactions
    • Controlled addition monitored via HPLC to minimize unwanted oligomerization

    Final product types

    • Selective post-emergent herbicides (e.g., substituted anilide actives)
    • Systemic triazole fungicides with aryl-ether structures
    • Intermediate inputs for ready-to-formulate pesticide technicals
    • Research compounds for agri-biotech pipeline development

    4. Monomer Component in High-Performance Polyimide Manufacturing

    Producers of advanced polymeric materials incorporate 3-Ethoxyaniline as a reactive monomer in the polymer backbone for selected polyimide and polyaramid applications requiring tailored flexibility, chemical resistance, and processability. Its incorporation influences polymer chain distribution, glass transition, and mechanical strength, with QC steps to monitor molecular weight and end-group fidelity in every batch, supporting sectors such as electronics, aerospace, and automotive engineering.

    Industry compliance standards

    • ASTM D5207 (Standard practices for polyimide thin films)
    • UL 746B (Polymeric Materials Performance for Industrial Parts)
    • ISO 9001:2015 for engineering plastics manufacturing
    • RoHS Directive 2011/65/EU for electrical/electronic equipment safety

    Typical usage ratio

    • 2–8% weight/weight in formulation; adjusted based on desired flexibility and chemical resistance for end-use application

    Downstream process integration

    • Co-polymerized with dianhydrides during imidization step in solvent-cast or melt process
    • Integrated as an end-group modifier in custom block copolymer designs

    Final product types

    • Flexible circuit insulators for electronics
    • High-temperature resistant films for automotive and aerospace cabling
    • Structural foams for composite part fabrication
    • Specialty adhesives for industrial equipment assembly

    5. Intermediate for Specialty Rubber Chemicals and Antioxidant Additives

    Industrial manufacturers engaged in rubber compounding use 3-Ethoxyaniline as a tailored intermediate in the production of age-resisting additives and antiozonant chemicals. Its molecular structure enables downstream producers to design compounds that effectively stabilize unsaturated elastomers against oxidative degradation and UV exposure, ensuring consistent vehicle tire, conveyor belt, and sealant performance in challenging environments.

    Industry compliance standards

    • ASTM D4670 (Rubber Antioxidant Test Methods)
    • ISO 9001 for chemical processing of rubber additives
    • REACH Annex XVII (restrictions on aromatic amines)
    • Automotive industry supplier qualification (IATF 16949)

    Typical usage ratio

    • 1–5 phr (parts per hundred rubber) in additive masterbatch formulations; level determined by base polymer and exposure profile

    Downstream process integration

    • Reacted as an intermediate with quinone or nitroso compounds to generate finished antioxidant molecules
    • Added to batch or continuous compounding lines prior to vulcanization stage

    Final product types

    • Polymer-bound antioxidant masterbatches
    • Finished rubber stabilizer packages for tire production
    • Long-life conveyor belt formulations
    • Heat- and weathering-resistant sealant compounds
    Free Quote

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    Email: admin@ascent-chem.com

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    Certification & Compliance
    More Introduction

    Introducing 3-Ethoxyaniline: Consistent Performance Rooted in Practical Manufacturing

    Experiencing 3-Ethoxyaniline Firsthand: From Bench to Bulk

    Inside our production facility, the story of 3-Ethoxyaniline (also known as meta-ethoxyaniline or 3-ethoxybenzenamine) starts with careful selection of starting materials and remains centered on reliable manufacturing practices. We have committed to robust and transparent batch processes, steering away from shortcuts that can compromise longevity or purity. The finished material comes as a pale yellow to brownish liquid, with an aromatic amine odor. In true everyday use, a well-made 3-Ethoxyaniline matters less as an abstract product and more as a keystone for several high-value downstream chemicals. Our manufacturing team tracks each step, aiming for minimal residual starting reagents and achieving high assay (typical purity above 99%) using gas chromatography and other established analytical methods.

    The bulk of the product heads into the hands of dye and pharmaceutical intermediate producers. 3-Ethoxyaniline’s structure, an aniline ring substituted at the meta position by an ethoxy group, gives it distinct behavior in further syntheses. Chemists working with us point to the benefit of having the ethoxy group at the 3-position: this substitution pattern influences downstream reactivity, often driving selective acylation, azo coupling, and other ring transformations that favor industrially relevant yields. Over the years, each kilo we ship builds on hard-earned process knowledge—constant monitoring of water content, distillation technique, and oxygen exclusion—all of which keep quality stable batch after batch.

    Guided by Experience: How 3-Ethoxyaniline Works in Real Chemical Manufacturing

    Many in the fine chemical space recognize the difference a true manufacturer brings to routine orders. From ordering to delivery, the consistency of 3-Ethoxyaniline’s physical characteristics—density (typically around 1.05 g/cm3), boiling point above 240°C, refractive index measurement, and color assessment—goes beyond mandatory specifications. These numbers reflect stable reaction times in the customer’s reactor, predictable separation steps, and a minimum of rejected batches. We have spent years tuning our process for clean distillation cut points and minimizing byproducts, lessons gained from both scaling up new lots and listening closely to feedback from our partners.

    Serious users spot even small impurities—trace colored byproducts or residual solvents—so all of our 3-Ethoxyaniline undergoes extra steps. We run active carbon filtration and pressure distillation, followed by post-processing tests for key spectroscopic signatures. This attention to purification cuts down maintenance headaches for our customers. It prevents fouling in downstream reactors, drift in analytical equipment baselines, and interruption of continuous production lines.

    How 3-Ethoxyaniline Differs: Specificity, Purity, and Real-World Value

    Navigating the choice between similar aniline derivatives, users notice real performance differences that stem from manufacturing practices. For instance, 3-Ethoxyaniline is distinct from 2- and 4-ethoxyaniline because substitution on the aromatic ring affects both chemical reactivity and application niche. In dye chemistry, where precision matters for both color and fastness, the meta-ethoxy substituent can lead to key shades and increased light stability in finished pigments. Pharmaceuticals and agrochemical developers benefit from the differentiated electron distribution this structure imparts on target molecules, opening unique routes not accessible from ortho- or para- analogs.

    Building quality into each drum starts with raw material traceability—continuous evaluation from procurement, reaction control, and careful temperature monitoring during every batch run. The final product stays stable in sealed containers, protected from light and moisture, avoiding unintended side reactions. Many trading houses chase short-term volume, but as a dedicated manufacturer, we see the cost of cutting corners. A minor impurity, left unchecked, can create headaches for downstream process chemists—triggering off-spec batch failures, side-reactions, or lost process time.

    Solving Industry Challenges: Bringing Hands-On Expertise to the Table

    We have seen frequent industry frustrations with unpredictable supply and product variability. In the past, new customers would approach us after getting inconsistent lots—mis-matched GC analysis, faint trace of yellowing in what should be water-clear liquid, or surprising byproducts during downstream reactions. The biggest difference comes down to process discipline: close monitoring of every stage, prompt equipment upkeep, and willingness to adjust when analytical data demands.

    Our operations team shares decades of cumulative knowledge. They bridge the gap between theory and practice: knowing when glassware needs to be swapped for stainless, which seals handle specific process solvents, or how slow temperature ramps prevent runaway polymerizations during synthesis. These choices define purity long before drums go onto pallets. We have learned the hard way how exposure to air or process leaks create off-spec batches. Now, we use nitrogen-blanketing and in-line sampling, ensuring each container matches both assay and application-specific color thresholds.

    Supporting Our Partners: Reliable Supply and Transparent Dialogue

    Our commitment shows up not as buzzwords, but as reliable timetables and real solutions to production observations. Customers sometimes face delayed or failed syntheses due to variable raw materials. We invite routine audits, provide open access to batch records and process flow diagrams, and encourage direct technical communication when questions arise. Problems do not resolve through silent shipping; solutions come from honest exchange. This is why we maintain detailed records from each lot and remain responsive through every production cycle.

    By sharing expertise gained from years of chemical manufacturing, we foster trust over short-term advantage. Staff at the blending lines, not just those in offices, understand the importance of job control: moisture checks, tank cleaning protocols, sample labeling, and fast corrective actions when specs approach minimum thresholds. Our partners in pharmaceutical development, dye synthesis, and specialty intermediates rely on stable, high-purity material. An experienced manufacturer supports process engineers at every step, carrying responsibility beyond the factory gate.

    Quality Standards: Testing, Documentation, and Continuous Improvement

    Many in the industry take for granted that “purity” means only a percentage on a sheet. Reality inside the plant goes deeper. Spectroscopic tests (NMR, IR) confirm not just the absence of contaminants but the expected functional groups and substituted rings. We constantly test for trace metal content, water, and secondary amines. Titration, GC-MS, and thermal stability checks give the assurance that each lot behaves as intended in high-temperature reactions and complex multi-step syntheses.

    We keep careful documentation to track trends in process data and spot root causes of variation. Where minor fluctuations show up, our technical teams meet regularly, comparing historical data and adjusting parameters in real time. We also work with key users to expand our understanding—if a specific impurity proves troublesome in a partner’s downstream step, we fine-tune purification steps rather than pass the problem along unseen. This transparency translates into real value, reducing shutdowns and delays not just for ourselves but for all hands involved all the way to finished products.

    Maintaining Environmental Responsibility Alongside Chemical Quality

    It’s not enough to deliver high-grade products; responsible practices count. We maintain closed-loop systems for handling solvents and byproducts, working within regulatory frameworks. Waste streams are tested and segregated, with on-site treatment and defined protocols for off-site disposal. Employees receive regular safety and handling training, learning both routine operation and immediate response actions. These steps cut risks to people and planet, keeping both product and process dependable.

    Our customers value the finished material coming from a production line where safety, environmental care, and consistent results are not in competition. We design processes to lower fugitive emissions and document traceability for every raw material. Permanent monitoring equipment makes sure batches stay within specified limits. This careful handoff—of product, knowledge, and commitment—forms the base for all long-term business, not just short-cycle orders.

    Technical Support and Application Guidance—Drawn from Practical Experience

    Since most end uses for 3-Ethoxyaniline depend on tightly controlled reaction conditions, technical support matters. Instead of passing on generic guidelines, we work directly with application chemists and process engineers to transfer insights. Questions come up about blending ratios, solvent compatibility, or use in multi-step syntheses. By maintaining open lines—phone, email, site visits—we ensure challenges find solutions grounded in lab and production floor knowledge.

    Experienced users care about reaction kinetics and final product yield. Over time, feedback has shaped our internal standards: for example, we continuously monitor trace secondary amines, which can affect next-stage reactivity. Our technical teams work side by side with customers, reviewing product samples and designing testing protocols. This ongoing dialogue leads to better run rates, fewer process hiccups, and long-term confidence with each incoming shipment.

    Addressing Industry Trends: Expectations, Innovation, and Trust

    The chemical sector faces intense pressure for greater transparency, product stewardship, and traceability. Customers expect not only minimum standards but consistent execution. We host regular audits—opening our processes for review and inviting detailed spot-checks. New requests for sustainability metrics and lower residual solvents push us to invest in better process controls and advanced analytical tools. Staff training focuses both on achieving chemical performance and on understanding the exacting needs of new classes of applications, from advanced dyes to next-generation active pharmaceutical ingredients.

    Recent years have brought a surge in demand from specific fine chemical and pharma innovators: researchers pushing boundaries with tailored reactive intermediates. 3-Ethoxyaniline has found new uses in targeted research projects, not only because of its structure but because of proven batch-to-batch dependability and a willingness to share supporting data. Instead of marketing pitches, we count repeat orders and technical inquiries as evidence that trust stems from tangible experience, not just rhetoric.

    Practical Solutions—Meeting Real Customer Challenges

    Downstream users sometimes face constraints that rarely show up in standard chemical literature: solvent recycling needs, safety restrictions, and operational limitations on scale. Our experience helps anticipate problems such as residues in process lines, slow crystallization, or premature reaction quenching caused by even trace byproducts. Over time, we’ve adapted by offering flexible container sizing, strict lot separation, and custom documentation packages tailored to specific end-uses.

    This detailed approach limits bottlenecks and reduces troubleshooting cycles. Our logistics team works within tight temperature and handling windows, ensuring every shipment reaches its destination without quality shifts. Chemical manufacturing consists of thousands of small decisions, each of which builds—or erodes—reliability. We keep learning from both missed opportunities and successful outcomes, constantly improving both process and service.

    Conclusion: Commitment Comes from Day-to-Day Attention

    Quality chemical manufacturing rests not just on technology, but on day-to-day care for materials, people, and outcomes. The production of 3-Ethoxyaniline reflects hands-on learning earned batch after batch: watching reactions, testing product, cleaning equipment, and responding quickly when data points shift. We have learned that experience matters—practice refines instinct, and lasting partnerships come from meeting real-world challenges head-on.

    Our team stands behind each lot of 3-Ethoxyaniline because it is more than just a product—it is the sum of every choice, from raw material check to final drum filling. Our partners count on this consistency to drive critical synthesis, and their feedback shapes the future of what we do. Reliable, high-purity 3-Ethoxyaniline is not the result of shortcuts but of perseverance, transparency, and pride in practical achievement. This is our commitment, and it marks the difference true chemical manufacturing brings to our industry.

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