3-Chlorophenol

    • Product Name: 3-Chlorophenol
    • Alias: m-Chlorophenol
    • Einecs: 202-713-4
    • Mininmum Order: 1 g
    • Factroy Site: Yudu County, Ganzhou, Jiangxi, China
    • Price Inquiry: admin@ascent-chem.com
    • Manufacturer: Ascent Petrochem Holdings Co., Limited
    • CONTACT NOW
    Specifications

    HS Code

    298546

    Chemicalname 3-Chlorophenol
    Casnumber 108-43-0
    Molecularformula C6H5ClO
    Molecularweight 128.56 g/mol
    Appearance Colorless to pale yellow liquid
    Meltingpoint 32-35 °C
    Boilingpoint 213-215 °C
    Density 1.27 g/cm3 at 20 °C
    Solubilityinwater 20 g/L at 20 °C
    Pka 8.92
    Flashpoint 92 °C (closed cup)
    Vaporpressure 0.19 mmHg at 25 °C

    As an accredited 3-Chlorophenol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Amber glass bottle containing 500 mL of 3-Chlorophenol, tightly sealed, labeled with chemical name, hazard symbols, and handling instructions.
    Shipping 3-Chlorophenol should be shipped in tightly sealed, corrosion-resistant containers, clearly labeled with hazard warnings. It must be transported in accordance with local, national, and international regulations for toxic and environmentally hazardous substances, typically as a Class 6.1 (toxic substance). Store upright in a cool, dry, and well-ventilated area during transit.
    Storage 3-Chlorophenol should be stored in a cool, dry, well-ventilated area, away from direct sunlight, heat sources, and incompatible materials such as strong oxidizers and acids. Keep the container tightly closed and properly labeled. Use corrosion-resistant containers. Store at room temperature, and avoid moisture and ignition sources. Ensure proper grounding and use secondary containment to prevent leaks or spills.
    Application of 3-Chlorophenol

    Applications of 3-Chlorophenol in Industrial Manufacturing

    3-Chlorophenol supports a range of critical chemical processes as a primary or intermediate raw material. Its controlled usage allows for precision in downstream applications, where batch consistency and regulated input ratios determine the performance and safety of final products. Below, our production experience details specific industrial application scenarios, with full attention to compliance and integration practices in the chemicals sector.

    1. Synthesis of Pharmaceuticals—Intermediate for Antiseptics and Disinfectants

    Pharmaceutical manufacturers use 3-chlorophenol as an essential starting compound in synthesizing certain antiseptic and disinfectant agents, particularly those derived from phenolic structures. Batch formulations require controlled phenolic content to meet monograph specifications, while in-house QC ensures residual levels remain within pharmacopeial limits. Its introduction occurs during defined steps of chemical synthesis, influencing the purity of downstream actives. Each batch undergoes validation to address GMP, pharmacopoeia, and toxicological profiles prior to supporting further formulation or tableting.

    Industry compliance standards

    • European Pharmacopoeia (Ph. Eur.) requirements for raw material purity
    • United States Pharmacopeia (USP) monographs for allowable residual solvents
    • Current Good Manufacturing Practices (cGMP) in API intermediate production
    • REACH (EC 1907/2006) registration and safety documentation

    Typical usage ratio

    • As process intermediate: 3–10% by mass, adjusted based on target molecule and conversion efficiency
    • Higher ratios for multi-step synthesis with low-yield transformation
    • Strict monitoring of molar equivalents to minimize unreacted chlorophenol residues
    • Adjusted downward for high-yield, one-pot reactions

    Downstream process integration

    • Charged into closed reactors during condensation or substitution phases
    • Reacted with aminating or alkylating agents under temperature-controlled conditions
    • Subject to aqueous or organic phase extraction during intermediate purification
    • Transferred into crystallization or isolation steps prior to final product conversion

    Final product types

    • Chloroxylenol and other antiseptic actives
    • Preservative agents for pharmaceutical and topical use
    • Medical disinfectant compositions for surface and instrument treatment
    • Intermediate blocks for veterinary pharmaceutical synthesis

    2. Agrochemical Active Ingredient Synthesis—Key Building Block for Herbicides

    The agrochemical sector utilizes 3-chlorophenol as a precursor in multi-stage syntheses targeting certain selective herbicide molecules. Manufacturers require consistently high assay and low organochlorine contamination, as both product safety and field efficacy arise from controlled input purity. It enters chemical reactions through monitored feed lines, which prevent cross-contamination in multipurpose plants. Agrochemical QC protocols and traceability systems track each batch along the active ingredient development process from bench scale to technical-grade output.

    Industry compliance standards

    • FAO/WHO Specification for the Quality Control of Pesticides
    • ISO 9001:2015 certified production systems for technical materials
    • REACH and CLP Regulation (EC 1272/2008) documentation
    • National agrochemical regulations (e.g., EPA in the US, GB/T Chinese standards)

    Typical usage ratio

    • Input ratio 5–15% dependent on targeted active and stage of synthesis
    • Lower ratios for short synthetic routes with direct substitution
    • Trace component removal monitored below 500 ppm in final technical concentrate
    • Higher loading for complex transformation requiring excess starting material

    Downstream process integration

    • Fed into reactors for chlorination, etherification, or coupling steps
    • Participates in batch or continuous flow mode based on plant configuration
    • In-process sampling for intermediate assay and impurity profiling
    • Subject to flash distillation or solvent stripping prior to conversion into formulated goods

    Final product types

    • Phenoxy herbicides (e.g., derivatives used for broadleaf weed control)
    • Pesticide technical concentrates
    • Safener compounds for crop treatment preparations
    • Agrochemical formulation intermediates supplied to downstream blenders

    3. Dye and Pigment Manufacturing—Intermediate for Speciality Colorants

    Producers of specialty dyes and pigments rely on 3-chlorophenol as a functionalized aromatic core for syntheses such as azo dye coupling and triphenylmethane pigment formation. Batch production demands strict input monitoring to avoid unwanted isomer formation and ensure chromatic stability. The phenolic structure helps define fastness and reactivity during coupling, while the halogen substituent tunes solubility. Controlled integration into chemical reactors preserves batch-to-batch quality, serving both direct textile dyeing agents and plastics colorants.

    Industry compliance standards

    • EN 71-3:2019 Safety of Toy Colorants (for pigment preparations in toys)
    • OEKO-TEX® Standard 100 for textile dye input materials
    • ISO 9001:2015 for pigment and dye manufacturing plants
    • CFR Title 21 (FDA) for food contact polymer colorants where applicable

    Typical usage ratio

    • Feedstock levels 2–12%, depending on dye type and molecular weight target
    • Lower ratios for high-reactivity coupling partners
    • Incremental feed possible in stepwise chromophore building
    • Input minimized for highly specific, low-volume colorant runs

    Downstream process integration

    • Dosed in stirred-tank reactors during coupling of diazo or aryl intermediates
    • Monitored during condensation, sulfonation, or alkylation stages
    • Centrifugation or filtration used to remove excess precursors
    • Post-reaction modification steps depending on pigment or dye grade required

    Final product types

    • Azo and anthraquinone dyes for textile and leather finishing
    • Colorants for high-performance plastics and printing inks
    • Specialty pigments for coatings and paints
    • Toners and color concentrates for industrial application

    4. Industrial Biocide Formulation—Preservation in Cooling Water and Metalwork Fluids

    Industrial formulators incorporate 3-chlorophenol as a biocidal agent in liquid preparations where effective microbial control is required, such as in cooling tower water treatment and metalworking fluid preservation. Its bacteriostatic and fungistatic effects are harnessed within strict maximum residue limits due to toxicological profile. Product dosage undergoes site-specific adjustment, and the substance enters blending tanks via metered dosing systems, often combined with other synergistic actives. Every batch entailing this compound is validated with microbiological challenge testing and monitored under occupational safety rules for volatile organochlorines.

    Industry compliance standards

    • Biocidal Products Regulation (EU) No 528/2012
    • US EPA FIFRA registration for biocidal actives
    • ISO 14001:2015 for environmental safety in chemical blending operations
    • German Water Hazard Class (WGK) for coolant preservatives

    Typical usage ratio

    • Blending levels usually 0.1–2% w/w depending on system volume and contamination risk
    • Lower range for retention in closed-circuit systems
    • Upper range for open recirculating or heavily soiled waters
    • Final concentrations in treated fluids meet mandatory local discharge parameters

    Downstream process integration

    • Metered addition into central blend tanks or point-of-use dosing stations
    • Stabilization mixing under inert or sealed conditions to limit volatilization
    • Quality checks for preservation efficacy, sensory characteristics, and residue control
    • Product packaged as ready-to-use biocidal concentrates or in multi-component systems

    Final product types

    • Cooling tower biocidal formulations for industrial HVAC systems
    • Metalworking fluid preservatives for cutting, grinding, and machining
    • Sanitizing agents for recirculating process water and cooling baths
    • Anti-fouling additives for closed-loop industrial water circuits

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    Certification & Compliance
    More Introduction

    3-Chlorophenol: Proven Chemistry for Demanding Applications

    What We See in 3-Chlorophenol

    At our facility, 3-chlorophenol forms one of the backbone molecules for both specialty and industrial chemistry. We synthesize it in-house using carefully monitored catalytic chlorination of phenol, following protocols refined by years of process experience. The final product comes as a pale, mobile liquid with a mild, phenolic odor and a precise specification for purity, usually not less than 99.5%. The model shipped from our plant follows the standard of “Industrial grade, Type A” favored by downstream processors. Our analytical instruments screen for byproducts like 2-chlorophenol and 4-chlorophenol and hold them below 0.3%, so users don’t fight with batch-to-batch variability.

    Where 3-Chlorophenol Makes an Impact

    Most customers ask about chlorophenols for their biocidal power or for use as building blocks in syntheses. In the day-to-day operations of pesticide, dye, and pharmaceutical makers, this compound acts as a reliable intermediate. Just as important, our clients in wood preservation see consistent treatment performance because our process keeps contaminants at a minimum. Buyers often compare our material with more generic imports or blends. Those options vary in color, purity, and reactivity. Where production lines depend on consistent reactivity or finished goods must meet food contact or technical grade standards, off-spec chlorophenol disrupts downstream reactions and can build up residues. We know what this means in practice: every percent of unwanted isomers can choke a distillation column, prolong filtering, and force costly equipment washes.

    Direct Experience with Handling and Processing

    After years managing the synthesis and pack-out of 3-chlorophenol, we pay particular attention to two factors—byproduct management and storage. On our line, temperature, residence time, and pH all receive strict control to suppress polychlorinated phenol formation. Failing to keep those unwanted isomers in check leads to downstream headaches from regulatory compliance to environmental safety. Our plant runs purges periodically to clear lines, chasing out stuck residues because they stubbornly resist routine cleaning. This effort shows up in customer feedback; our regular buyers tell us less process downtime and better batch yields than third-party alternatives.

    Specification Choices and What They Mean for Use

    In this plant, specification isn’t just a matter of number chasing. Beyond the headline value for assay, users get real-world reliance on controlled acidity, color, and physical quality. A typical batch will read below 50 APHA on the color scale. In wood treatment or industrial biocides, this low color prevents unsightly stains or product darkening, which matters when end-use customers see the product surface. Low acidity comes from the elimination of acid-washed byproducts before the final formulation. If the acidity runs higher, end-users experience corrosion of piping or residue on pumps, issues we’ve learned to avoid by managing the final stage of synthesis tightly.

    3-Chlorophenol versus Neighboring Chlorophenols

    Chemically, the difference between 3-chlorophenol and other isomeric chlorophenols matters. Our team works with not just 3-chloro, but also 2-chlorophenol and 4-chlorophenol. 3-chlorophenol’s placement of the chlorine atom in the meta position gives it a distinct reactivity profile. In pesticide intermediate workflows, for example, the reactivity changes the efficiency of coupling and further substitutions. Some clients require the ortho or para isomers for specific reactions—each comes with unique handling and toxicity profiles, regulatory demands, and thermal properties. Our experience confirms that using the wrong isomer can disrupt an entire batch, waste precious reagents, or go out of spec for regulatory filings. We keep isomers well separated, with strict process validation, as cross-contamination can move trace impurities across an entire production campaign.

    Performance in Real-World Applications

    We have shipped thousands of tons of 3-chlorophenol for use in slimicide formulations, controlling bacteria and fungi in paper manufacture. Here, the strict specification translates to fewer process upsets, predictable feed dosing, and consistent microbe suppression. Dye and pigment manufacturers value our process purity because even fractions of other isomers or byproducts can raw material filters or drop yields during the sulfonation and coupling stages. When serving pharmaceutical clients, every contaminant traced back to upstream chlorophenol reactions triggers an investigation or, worse, product recalls. We test our product with high-performance liquid chromatography and GC-MS to identify even trace non-phenolic contaminants. This testing, built into our process, reflects lessons learned by uncovering the insidious ways unwanted chlorinated byproducts interfere with enzyme-based syntheses and biologically active molecule production.

    Why Control of Trace Impurities is Critical

    Trace impurities in 3-chlorophenol receive intense focus because of the high downstream technical requirements in many industries. Some phenolic contaminants, leftover from incomplete synthesis or storage degradation, can drive up background UV absorbance or add chemical noise in other analytical monitoring steps. If these slip through, they clog chromatography columns and force users to spend time and money on additional purification. Over the years, we developed custom adsorber columns for crude stream polishing to slash these effects and restore clarity to finished batches.

    Emissions from phenolic production hold particular health significance, and nowhere is this more visible than in environmental monitoring of effluent streams. 3-chlorophenol features in regulatory requirements as a priority pollutant, and our plant minimizes emissions within strict limits, monitored by real-time sensors integrated with plant DCS (Distributed Control System). Regular audits and non-routine sampling keep the system honest—an approach built in response to increasing requests for environmental traceability from both customers and regulators.

    Handling and Risk Minimization Based on Field Lessons

    With an aromatic hydroxy group and a chlorine substituent, 3-chlorophenol is more persistent and toxic in the environment than simple phenol, so we equip our tank farm and shipping operations with extra containment, vapor recovery, and real-time leak detection. Years of work have taught us to favor single-use drum liners for export shipments, since even trace residues create odor or contamination in reused containers. Trucks and storage tanks receive regular ultrasonic testing for corrosion, as this compound, over time, can cause micro-pitting or embrittlement even with lined storage. Customer complaints often arise from rust or oil contamination, not the compound itself, and we keep these at bay by following a tank-cleaning regimen that never skips steps.

    What Customers Say About 3-Chlorophenol in Daily Use

    Our clients, mostly manufacturers of formulated chemicals and intermediates, report direct process improvements with our high-assay material. Downtime shrinks, and raw material losses drop as fewer off-gassing events and failed lots occur. Plant operators tell us that easier pumping and better filterability result from the material’s lower paraffin and residue content—issues that show up clearly if less refined product enters their lines. Our technical team often receives calls when buyer’s operations struggle with viscosity spikes or feed inconsistencies after switching to low-cost alternatives from resellers or blended batches. We’ve audited multiple customer plants, tracing contamination issues to supplier changes that introduced off-spec lots where trace 2- or 4-chlorophenol exceeded 0.5%. By collaborating on root cause analysis, we've built a cycle of trust and feedback that informs every process improvement in our facility.

    Regulatory and Safety Realities

    Regulators treat 3-chlorophenol as a hazardous molecule with both acute and chronic health risks if mishandled. We match our safety data management with on-site handling protocols based on the latest regulatory frameworks including REACH and TSCA listing requirements. Our site follows a lockstep sequence of PPE, received material check-in, and double containment for all bulk movements. Customers appreciate that shipments come with full analytical history and compliance declarations, offering confidence for their compliance audits. By shipping with clear hazard labels, sealed tamper-evident closures, and batch traceability, we avoid the issues that come from accidental mislabeling or mishandling in downstream warehouses.

    Why We Continue to Focus on 3-Chlorophenol

    The decision to maintain our dedicated 3-chlorophenol line rests on steady, diversified customer demand and the layered expertise developed across decades. This compound’s place as both a chemical building block and functional ingredient gives our team a recurring challenge and ongoing satisfaction. We engage with research groups, chemical engineers, and industrial users who bring us problems to solve, often involving tighter impurity control or more consistent batch delivery. Our process team leverages newer catalysis options and inline analytical controls to respond to requests for tighter specifications—such as below 0.2% for certain critical applications. Each plant upgrade represents direct feedback we’ve gathered from users struggling with legacy supply problems or adapting to new product lines.

    Technical Support and Partnership

    Technical support extends long past the point of sale. We regularly handle troubleshooting calls on storage, blending, or new application development. Our application chemists maintain thorough technical dossiers that include not just the regulatory aspects but also precision handling tips for blending or downstream reaction management. Partners appreciate our approach to joint development, where we review lab-scale reactions with their process chemists, tweaking supply parameters to match exact needs for next-generation products. When users run into plant upsets or quality issues, we keep a direct communication line, offering root cause investigations informed by plant-level forensic testing.

    The Market Landscape and Supply Chain Realities

    The last few years have shown that securing a reliable source of 3-chlorophenol means more than just price negotiation. Spikes in energy costs and supply disruptions have made process efficiency and plant uptime essential. Our plant staffs redundant process engineers and chemists to ensure 24-hour coverage and fast issue resolution. We prequalify all upstream suppliers and test each inbound phenol lot for trace contaminants, knowing that feedstock purity wavers and can impact finished assay or color. Buyers who try to chase low costs or resellers almost always return when variable supply lines fail to meet new product launch deadlines or customer audits.

    From our view at the production site, the ability to maintain specification and mitigate interruptions directly results from our investment in process controls and skilled operators. Shipping windows stay tight because we maintain finished goods inventory and work with logistics providers who understand phenolic shipping hazards, reducing the risk from seasonal delays or weather disruptions.

    Sustainability and Future Developments

    Every year, regulations tighten around chlorinated organics, and we anticipate further changes in allowed discharge levels or workplace exposure standards. Our environmental and safety protocols evolve with these rules and with our customers’ own product stewardship updates. Solvent and purge recovery systems run at the highest practical efficiency, aiming to cut process waste and emissions year after year. We adopted automated leak detection and response technology across the site, reducing the risk of unplanned releases, and so far, this has kept our incident record clean. Continuous improvement in plant safety and environmental footprint remain essential, not just for compliance but to attract the high-value customers that increasingly screen suppliers for sustainability performance.

    Conclusion: 3-Chlorophenol in Practice

    After decades synthesizing, analyzing, and delivering 3-chlorophenol, our team’s perspective rests on solving real problems—batch after batch. Experience in plant operations, direct customer partnerships, and unbroken feedback loops let us see where process refinements or extra controls tighten quality or unlock new use cases. A deep familiarity with how 3-chlorophenol actually functions in hundreds of customer lines helps us distinguish ourselves from traders or repackers. It’s not about hitting a spec sheet but about delivering performance users can measure in uptime, yield, and safety. This ongoing cycle—production, feedback, improvement—anchors our confidence in this molecule and our commitment to producing it at the highest standard every time.

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