Products

3-Chloronitrobenzene

    • Product Name: 3-Chloronitrobenzene
    • Alias: m-Chloronitrobenzene
    • Einecs: 203-613-2
    • Mininmum Order: 1 g
    • Factroy Site: Yudu County, Ganzhou, Jiangxi, China
    • Price Inquiry: admin@ascent-chem.com
    • Manufacturer: Ascent Petrochem Holdings Co., Limited
    • CONTACT NOW
    Specifications

    HS Code

    796440

    Chemical Name 3-Chloronitrobenzene
    Cas Number 99-54-7
    Molecular Formula C6H4ClNO2
    Molecular Weight 157.55 g/mol
    Appearance Pale yellow crystalline solid
    Melting Point 47-49 °C
    Boiling Point 272-273 °C
    Density 1.45 g/cm³
    Solubility In Water Slightly soluble
    Flash Point 140 °C
    Smiles C1=CC(=CC(=C1)Cl)[N+](=O)[O-]
    Pubchem Cid 7539
    Iupac Name 1-chloro-3-nitrobenzene

    As an accredited 3-Chloronitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 3-Chloronitrobenzene is packaged in a 500g amber glass bottle with a secure screw cap and clear hazard labeling.
    Shipping 3-Chloronitrobenzene should be shipped in tightly sealed containers, clearly labeled, and compliant with hazardous material regulations due to its toxic and potentially harmful nature. Transport it in accordance with local, national, and international guidelines, such as DOT, IATA, or IMDG requirements, ensuring proper handling to prevent leaks, spills, and exposure.
    Storage 3-Chloronitrobenzene should be stored in a tightly closed container, in a cool, dry, and well-ventilated area away from direct sunlight, heat, and sources of ignition. Keep it separated from incompatible materials such as strong oxidizers, strong bases, and reducing agents. Ensure proper labeling, and avoid storage near food and beverages. Use secondary containment to prevent accidental spills or leaks.
    Application of 3-Chloronitrobenzene

    Applications of 3-Chloronitrobenzene in Industrial Manufacturing

    Our experience as a direct producer of 3-Chloronitrobenzene supports manufacturers in the agrochemical, pharmaceutical, pigment, and polymer sectors. Below, we detail practical integration paths, compliance requirements, dosage, and end-product types for major industrial applications.

    1. Herbicide Intermediate Manufacturing

    Major agrochemical producers utilize 3-Chloronitrobenzene as a precursor in synthesizing selective phenoxy herbicides. It reacts in nucleophilic substitution with phenols to form downstream intermediates, crucial in products designed for cereal crop protection. Our technical collaboration with large-scale formulators supports batch and continuous flow applications, ensuring sustained yield and purity.

    Industry compliance standards

    • REACH (EC No. 1907/2006)
    • China Pesticide Registration (ICAMA)
    • US EPA Pesticide Chemicals Regulations (40 CFR Part 180)
    • ISO 9001:2015 Quality Management

    Typical usage ratio

    • Employed at 0.9–1.1 molar equivalents relative to phenolic reagents. Adjust ratios to balance yield and purification efficiency, typically maintaining 35–45% w/w of active ingredient in the reaction batch.

    Downstream process integration

    • Feeds directly into the etherification or reduction step after solvent dissolution.
    • Processed under controlled temperature and pH to maximize specific intermediate formation for herbicide actives.
    • Chemical conversion occurs in dedicated reactors with inline monitoring for residual chloride.

    Final product types

    • Herbicide technical concentrates (e.g., MCPA esters, MCPB, Mecoprop)
    • Selective cereal crop protection formulations
    • Premixed granular herbicide blends
    • Bulk powder intermediates for export

    2. Pharmaceutical Intermediate—Paracetamol Precursors

    Our 3-Chloronitrobenzene is an essential nitration substrate in multi-step synthesis routes for pharmaceutical intermediates, including those leading to paracetamol derivatives and certain active pharmaceutical ingredients (APIs). Controlled hydrogenation and further functionalization steps demand consistent quality, traceability, and impurity profile, which we rigorously manage.

    Industry compliance standards

    • GMP for Active Pharmaceutical Ingredients (ICH Q7, EU GMP Annex 8)
    • USP/NF & EP grade raw material traceability systems
    • FDA 21 CFR Part 210/211
    • ISO 9001:2015 for API supply chains

    Typical usage ratio

    • Typical input of 0.98–1.02 molar equivalents in nitro reduction stages, depending on downstream route efficiency. Solution batches usually target 25–33% w/w active per reactor load.

    Downstream process integration

    • Charged during initial condensation with acetaminophen backbone formation compounds.
    • Undergoes reduction (catalytic hydrogenation) before coupling, completed in cGMP-compliant, closed systems.
    • Reaction profile monitored for residual chlorinated byproducts per pharmacopeial standards.

    Final product types

    • Primary paracetamol intermediates
    • API precursors for analgesics/antipyretics
    • Bulk intermediates for export or in-house tableting
    • Further processed pharmaceutical-grade intermediates

    3. Dyestuff and Pigment Production

    Specialty pigment and dyestuff manufacturers use 3-Chloronitrobenzene in azo coupling and reduction processes. The compound plays a critical role in obtaining specific chromophore structures imparting vivid color shades to textile, plastic, and ink sectors. We supply consistent bulk reactivity analysis to help colorant manufacturers meet stringent end-use standards.

    Industry compliance standards

    • EU REACH Regulation (Annex XVII Restrictions)
    • EN 71-3:2019 (Toy Safety—Migration of certain elements)
    • OEKO-TEX® Standard 100—Class I & II input material compliance
    • ISO 14001 Environmental Management for dye plants

    Typical usage ratio

    • Used at 1.00–1.05 molar equivalents for mono- or di-azo pigment synthesis. Typical batch concentrations range from 28–36% w/w depending on pigment depth and performance requirements.

    Downstream process integration

    • Integrated at early coloration step in azo compound formation by coupling with diazonium salts.
    • Employs water or solvent-based slurry reactors for improved dispersion and fast reaction kinetics.
    • Residual chloronitro intermediates managed by filtration and purification before commercial dispersion.

    Final product types

    • Disperse dyes for synthetic fiber coloration
    • Azo pigments for coatings and inks
    • Waterborne textile dye preparations
    • Plastic and rubber color concentrates

    4. Polymeric Material Synthesis—High-Performance Polymers

    Advanced plastics and elastomers manufacturers rely on 3-Chloronitrobenzene as a starting monomer for producing specialty aromatic polymers. Nucleophilic aromatic substitution and subsequent amination yield functional building blocks used in heat-resistant and chemically stable polymer chains. Our controlled impurity levels ensure downstream polymerization performance without unacceptable byproduct formation.

    Industry compliance standards

    • EU Regulation (EC) No. 1935/2004 for food contact materials
    • UL 94 (Flammability Standard for Plastics)
    • ASTM D638—Tensile Properties of Plastics
    • Quality systems certified to ISO 9001:2015

    Typical usage ratio

    • Implemented at 0.95–1.10 molar ratio relative to comonomers. Reaction mass formula typically uses 15–25% w/w for aromatic backbone synthesis, tailored to molecular weight targets.

    Downstream process integration

    • Introduced at initial polymerization feed stage after pre-dissolution in inert organic solvent.
    • Undergoes nucleophilic aromatic substitution with diamine derivatives, followed by condensation and chain extension.
    • Process control maintains conversion level to limit oligomeric byproduct formation.

    Final product types

    • High-temperature-resistant polymers
    • Specialty copolymers for electronic insulation
    • Elastomeric materials for automotive and aerospace
    • Composite resins for advanced engineering parts

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    Certification & Compliance
    More Introduction

    3-Chloronitrobenzene: A Manufacturer’s View on Quality, Consistency, and Application

    Introduction to 3-Chloronitrobenzene

    Every molecule counts in fine chemical manufacturing. Among the aromatic nitro compounds, 3-Chloronitrobenzene continues to be a staple in our production lines—not because it’s new or rare, but because demand for consistent, high-purity intermediates never disappears from the market. Our direct manufacturing approach allows us a perspective that moves beyond bulk listings and technical jargon. Years of hands-on experience with this product have shown us what users value and what the industry seeks in reliable feedstocks.

    Our Manufacturing Focus: Quality and Purity at Scale

    3-Chloronitrobenzene stems from a careful chlorination process of nitrobenzene. What sets high-grade product apart is not just percentage purity, but how tightly the specification gets held across batches. From a finished goods perspective, we keep the purity above 99% on a typical lot, verified with GC and HPLC. We routinely screen for residual nitrobenzene, ortho- and para-isomers, and volatility losses. Each parameter reflects feedback from decades of downstream users.

    Product quality begins upstream, with choice of raw nitrobenzene and handling of chlorination reactors. Equipment design, temperature profiles, and precise feeding control have direct impact on isomer ratio. We pay close attention to both the main mononitration step and subsequent chlorination—clean runs reduce side-product formation, which in turn means less waste downstream.

    Moisture content matters, too. Even a small uptick in water can complicate reactions in dye or pharmaceutical syntheses. Our process design and packaging keep moisture content as low as possible. Several times over the years, we have helped customers diagnose and fix performance issues directly traced to sources of trace water or inconsistent melting points found in products from other origins.

    Tailoring Particle Size and Crystal Form

    We learned early on that 3-Chloronitrobenzene’s performance in further steps is affected by its solid form. Some industries benefit from finer, free-flowing powders, while others opt for larger flakes to reduce dust and static. We offer multiple cuts—fine, standard, or granular—by adjusting the cooling and milling protocols rather than resorting mainly to sieving, which damages particle integrity. These differences can seem minor at first, but regular users have told us it saves them time and headaches on their production lines.

    Over the years, we tried various methods to achieve consistent flow properties, testing anti-caking agents and different packaging films. Eventually, we found that a slightly modified cooling rate after crystallization did a far better job of minimizing agglomeration, without the need for additives.

    Applications: Where 3-Chloronitrobenzene Goes Next

    Most of our customers use 3-Chloronitrobenzene as a building block rather than an end product. Its applications extend into pharmaceuticals, dye manufacture, agrochemical synthesis, and many specialty chemical fields. In dye chemistry, it stands out for creating vivid, stable colorants, especially after reduction to the appropriate amines or further nucleophilic substitution. Pharma manufacturers prize it for its reactivity at both the nitro and chloro positions—a combination not offered by every substituted benzene.

    During technical support calls, the conversation often circles back to impurity profiles. Depending on the downstream transformation, even a small percentage of ortho-isomer can affect yields or crystallization of active pharmaceutical intermediates. We share full impurity data openly with our partners; several multinational pharmaceutical firms rely on us for this transparency, which often leads to new projects.

    For the agrochemical sector, we regularly supply 3-Chloronitrobenzene as an advanced intermediate, often one or two steps ahead of a formulated herbicide or pesticide. This market places a premium on batch-to-batch reproducibility and incoming material traceability. Unlike some distributors who mix sources, we never blend materials from different reactors, even for bulk shipments. This traceability gives our customers peace of mind should issues arise during registration or regulatory audits.

    Practical Differences from Related Products

    Customers often ask about differences between the 3-, 2-, and 4-Chloronitrobenzene isomers. From a synthetic perspective, the meta (3-) isomer gives unique reactivity. The electronic distribution on the benzene ring enables selective transformation by nucleophiles or reductants, although it is less reactive toward nucleophilic aromatic substitution than the para (4-) isomer. That trait can help in certain routes, where high selectivity is required.

    Among nitrobenzenes, only 3-Chloronitrobenzene strikes a balance between reactivity and stability at room temperature, making it safer and easier to store versus more active, less stable analogs. Users often compare it with 3-Bromonitrobenzene as well. Bromine compounds tend to be more expensive and harder to transport under regulations. Chlorine substitution gives most of the same chemistry, often with less environmental and cost burden.

    Some buyers mistakenly see all grades as interchangeable. That perspective costs time and resources in the long run, as sub-grade material can force extra filtration, lead to off-color issues in dyes, or even prompt failures in process qualification. We routinely provide side-by-side samples, demonstrating significant color and yield differences in finished products that stem directly from small variations in feedstock quality. That level of technical feedback comes only through long-term partnership and responsiveness—a point often overlooked by those purchasing solely on price.

    Handling, Storage, and Logistics—Based on Hard Experience

    Over years of production, we watched how seemingly minor issues with bulk packaging can snowball into inventory headaches. Bulk bags, steel drums, and lined cartons each have their place depending on customer requirements. We found that lined steel drums offer the best compromise for long-haul shipments in hot, humid climates. Early in our export career, losses from moisture ingress or compaction led us to invest in different drum linings and vapor-tight seals. Problems caused by inadequate packaging typically show up only after the material has crossed borders or sat in storage for a few weeks, making quick replacement difficult and costly.

    We don’t just sell and ship—our teams support with hands-on experience, helping optimize unloading and storage routines, sometimes down to finding the right warehouse microclimate or custom rack system. Unexpected temperature swings, especially in continental climates, can bring condensation or even melting. We worked with partners in Central Asia and South America to develop best practices for warehouse management, sometimes sending technical teams on-site as part of project launches.

    Some manufacturers still ship 3-Chloronitrobenzene in basic sacks, based on cost reduction. Eventually, returns and claims erode any initial savings. Through long-term tracking, we see less than 0.1% complaint rate with sealed, lined drums—feedback that shapes every packaging upgrade we invest in.

    The Human Side: Collaboration, Scale-Up, and Problem Solving

    Every batch gives us a chance to strengthen technical partnership. The same intermediate may approach very different end purposes depending on the user—some customers scale up into metric tons for established dye or herbicide markets, others order small high-purity quantities for early-stage pharmaceutical development. These differences come with their own challenges, and we treat them as opportunities to refine our processes and technical support.

    A common question during new project launches involves reaction scalability. Customers want confirmation that lab-benchmark purity holds true for their larger campaigns. Our in-house chemists work with pilot teams to transfer reaction results from glass reactors to full-scale production. We’ve documented real cases where scale-up introduced subtle impurities barely seen in lab analysis, requiring process tweaks to keep downstream purity intact.

    On rare occasions, customers reported unexpected performance drops using our 3-Chloronitrobenzene—often traced back not to our own batches, but to minor changes in auxiliary reagents or water content during their operations. We take ownership of process review, not simply for our own material but for the full chemical supply chain. Several partnerships have grown precisely from our willingness to track down root causes beyond the basic seller-buyer relationship.

    The most rewarding moments come when persistent troubleshooting leads to better yield, fewer filtration steps, or saved utility costs for our partners, building trust that lasts longer than any contractual arrangement.

    Sustainability and Regulatory Pressures: Our Direct Response

    Beyond technical delivery, sustainability and compliance shape every aspect of manufacturing. In our production, emissions, residue handling, and waste minimization drive both plant upgrades and daily routines. Chloronitrobenzene compounds face increasing regulatory scrutiny, especially in Europe and North America. We dedicated process engineers to continually lower our environmental footprint. We capture chlorinated byproducts, maximize recycling, and routinely submit samples for independent environmental testing. These aren’t abstract commitments—they flow from the reality of plant inspections and ongoing audits at our sites.

    From a regulatory perspective, working as a direct manufacturer means absorbing changes years before resellers experience them. Regulatory registrations require not just paperwork, but full analytical and toxicological disclosure of material origins, impurity levels, and traceability protocols. Our documentation extends far beyond certificates of analysis, covering full dossiers and validation data for our largest pharmaceutical and agrochemical users.

    Our customers call for supply chains they can trust, knowing that non-compliant or off-spec batches not only disrupt their production, but introduce legal risks and expensive recalls. We regularly share compliance documentation, GHS labeling, and safety data at the project planning stage, not only after a purchase order. Mutual transparency brings smoother, more reliable project launches in heavily regulated sectors.

    Supporting Innovation, Not Just Commodity Supply

    Manufacturing isn’t just about making the same product year after year. Our R&D initiatives focus on tweaking both process chemistry and end-use potential. In collaboration with key clients, we explored catalytic methods to reduce reaction temperatures and waste. In some pilot projects, we trialed biobased solvents and continuous flow reactors, delivering better yields and energy utilization. These improvements benefit not just our own cost structure, but lower the environmental impact for every stakeholder downstream.

    By keeping technical dialogue open, we take up customer suggestions, sometimes piloting small changes that improve solubility or reactivity for particular end products. In the past few years, requests from the electronic chemicals industry prompted us to develop ultra-high-purity 3-Chloronitrobenzene, filtered at submicron accuracy, to help meet the needs of next-generation materials. These niche derivatives get developed faster through manufacturer-user feedback and practical trials than they ever would by piecemeal sourcing or contract development alone.

    The feedback loop between users and our R&D teams fuels new application discovery. Customers from the flavors and fragrances sector, for example, prompted studies into trace contamination levels, leading us to install new analytical equipment. Small improvements in purity, sometimes measured at parts per billion, yield downstream benefits for the customer that we measure in fewer lost batches or better color performance. Each learning cycle tightens up our process controls and strengthens our supplier reputation.

    Market Trends and Future Outlook

    Our position as a direct chemical manufacturer puts us close to market shifts in both supply and demand. Over the past ten years, downstream demand for 3-Chloronitrobenzene has shifted from primarily dyes and pigments to more specialty, regulated applications. Buyers need evidence of both regulatory compliance and robustness in supply chain security. We’ve seen that market volatility, such as fluctuations in energy and halogen prices, directly impacts our cost base and sometimes supply continuity, particularly during global disruptions.

    Experience tells us that stable, long-term partnerships with regular users are more valuable than simply trading spot deals. Forecasting based on customer input allows us to plan investments in capacity and pollution control, passing real benefits back in the form of supply security and stable pricing.

    Supply chain bottlenecks—whether from shipping restrictions, new export controls, or raw material shortages—can disrupt global flows within weeks. Over two decades, we built up inventory and logistics buffers, drawing from lessons learned during previous crises. We proactively communicate expected challenges to our partners, arranging for early orders or alternate shipping channels as needed. Availability and price matter, but reliable technical communication and a willingness to adapt keep projects and plants running.

    As regulations in Europe and North America intensify and new environmental standards come online, we continuously adapt plant infrastructure and analytical protocols. We view this as opportunity rather than mere cost; those who adapt fastest maintain their market lead, while those who lag get forced to exit or shift entirely to unregulated markets.

    Pride in Direct Manufacturing: More Than a Supply Role

    Our hands-on production experience with 3-Chloronitrobenzene has shown that quality, consistency, and service make the real difference in application success. Having navigated decades of market cycles, regulatory changes, and technical advances, we see our role not just as material suppliers, but as technical collaborators and problem solvers. Every metric ton we ship reflects years of process tuning, customer feedback, and a commitment to quality rooted in day-to-day manufacturing, not simply sourcing or trading.

    The chemical industry moves fast, but time-tested relationships and continuous product improvement help everyone succeed. Through ongoing investment in plant, people, and process control, we support our customer's goals for consistent, reliable, and compliant chemical feedstocks in an ever-evolving marketplace.

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