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HS Code |
830406 |
| Chemical Name | 2-Nitrophenol |
| Cas Number | 88-75-5 |
| Molecular Formula | C6H5NO3 |
| Molecular Weight | 139.11 g/mol |
| Appearance | Yellow crystalline solid |
| Melting Point | 45-47 °C |
| Boiling Point | 218 °C |
| Solubility In Water | Moderately soluble |
| Density | 1.48 g/cm³ |
| Flash Point | 122 °C |
| Iupac Name | 2-nitrophenol |
| Pubchem Cid | 980 |
| Smiles | C1=CC=C(C(=C1)O)[N+](=O)[O-] |
As an accredited 2-Nitrophenol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | Amber glass bottle, 100 grams, with hazard labels, tightly sealed cap, chemical name and CAS number clearly marked on the label. |
| Shipping | 2-Nitrophenol is shipped as a hazardous chemical due to its toxic and potentially harmful nature. It is transported in tightly sealed, clearly labeled containers designed to prevent leakage or contamination. Shipping must comply with local and international regulations, including proper documentation, material safety data, and use of appropriate protective packaging. |
| Storage | 2-Nitrophenol should be stored in a tightly closed container in a cool, dry, well-ventilated area away from incompatible substances such as strong oxidizers and bases. Protect it from light and moisture. Keep it away from heat or open flame. Properly label the container and ensure it is stored in a designated chemical storage cabinet, preferably one suitable for corrosive or toxic chemicals. |
Applications of 2-Nitrophenol in Industrial Manufacturing2-Nitrophenol serves as a crucial intermediate in a number of chemical industries. Its primary value lies in specialized downstream syntheses where precise purity and functional group performance directly affect processing reliability and final product quality. As a manufacturer, we support strict regulatory compliance and application-tailored supply in multiple sectors, each outlined below based on actual market use. 1. Synthesis of Dye IntermediatesManufacturers in the dye industry use 2-Nitrophenol to prepare azo and anthraquinone dye intermediates. The material typically enters the diazotization or coupling stages due to its reactivity as a nitroaromatic compound. Technical teams closely monitor the degree of substitution and purity, since side reactions can lead to inconsistent dye hues and reduced tinctorial strength. Process optimization frequently centers on controlling pH, temperature, and catalyst levels to maximize yield across continuous or batch operations. Industry compliance standards
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2. Pharmaceutical Intermediate ManufacturingPharma synthesis operations select 2-Nitrophenol as a core building block for certain active pharmaceutical ingredients (APIs) and side-chain extended intermediates. Medicinal chemists employ it during etherification, condensation, or reduction steps to introduce controlled nitro or hydroxy functionalities. Extensive in-process QC safeguards against batch-to-batch variation. Accurate molar ratios and reaction timing are essential for optimizing downstream yield, especially in multi-step API synthesis where residual impurities may affect pharmacopurity and regulatory filings. Industry compliance standards
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3. Agrochemical SynthesisIn modern crop protection chemistry, 2-Nitrophenol serves as a tailored intermediate for selective herbicides, fungicides, and soil treatment agents. Downstream producers utilize it during ether linkage formation or ring modification steps, capitalizing on its electronic and steric properties. Production processes must balance reactivity and selectivity, while environmental, health, and safety management drives batch characterization and waste stream controls. Flexible tank and inline reactor systems dominate to minimize cross-contamination with other agrochemicals. Industry compliance standards
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4. Rubber Chemical Additives ProductionProducers of rubber processing chemicals add 2-Nitrophenol as a reactant in the synthesis of antioxidants and antiozonants. Its phenolic structure anchors subsequent alkylation and sulfonation reactions, delivering high-performance additives that protect finished rubber goods from oxidative and thermal degradation. Plant managers focus on accurate feeding and consistent purity, as off-ratios or impurities can significantly reduce antioxidant effectiveness or alter vulcanization characteristics in the final rubber matrix. Industry compliance standards
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5. Photographic Chemical ManufacturingIn the production of photographic developers and image stabilizers, 2-Nitrophenol acts as a reducing agent precursor and auxiliary stabilizer. Manufacturers precisely meter its addition to maintain optimal production of phenolate ions, which participate in color formation or silver halide stabilization. Analytical labs track impurities at low ppm levels to prevent fogging, image distortion, or accelerated degradation in processed films and photo papers. Industry compliance standards
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6. Corrosion Inhibitor FormulationSome specialty manufacturers incorporate 2-Nitrophenol as a functional additive in corrosion inhibitors for industrial water systems and metalworking fluids. Due to its aromatic nitro structure, it forms chelating complexes with metal ions and slows oxidation at the surface interface. Production lines prioritize monitoring for contaminant ions and particle sizing to avoid downstream filter clogging and ensure stable dispersions in storage and use. Industry compliance standards
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Competitive 2-Nitrophenol prices that fit your budget—flexible terms and customized quotes for every order.
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In our world, chemicals don’t just fall out of the sky ready to use. Each batch, each kilogram, comes from hands-on work, real investments, and choices that affect everything from cost to reliability. 2-Nitrophenol has been a staple both for research and industrial synthesis for decades. We make it in bulk and at small scales, depending on the demand—open to working with a chemist looking for a few grams for a project, as well as a plant manager sourcing tons for downstream chemistry. What makes 2-Nitrophenol valuable isn’t just its chemical formula or the yellow tint known by lab technicians worldwide. It plays a specific role in real processes and that’s why we invest time, equipment, and care in getting it right.
Let’s be up front: Not all 2-Nitrophenol comes out equal. The quality depends on starting materials, reaction control, purification steps, and how it’s handled every step of the way. We’ve tuned each part of our process, aiming for a material free from excess water, isomeric contamination, and leftover acidity. Our 2-Nitrophenol comes as a yellow crystalline powder. Depending on specification requests, we offer material with purity above 99.5%, and always document heavy metal content, moisture, and trace byproducts. What sometimes gets overlooked is the reality that small changes—say, too much moisture, or higher ortho/para isomer content—can disrupt lab reactions and industrial runs. Our quality checks involve not only HPLC, but also methods developed in-house with repeated feedback from customer labs. Every step aims for consistency, not just to chase technical standards, but because our own teams use these chemicals in daily research and production.
Every chemist recognizes the role of 2-Nitrophenol as a building block. It doesn’t make headlines, but it sits behind dozens of actual products found on the market—from dyes to pharmaceuticals. In dye synthesis, 2-Nitrophenol adds not only function but also stability to colorants that endure tough environments. We’ve watched pigment teams rely on its reactivity to create specific shades that hold up to sunlight, solvents, and heat. In pharma, it’s not just a starting material. It’s a step toward more complicated molecules, and every impurity can travel through the route, multiplying problems later. Manufacturing antifungal ingredients, for example, requires confidence that each intermediate meets rigorous controls. It’s not just about what’s present, but what’s not present—no excess ortho- or para-nitrophenol, very low metal traces, and absence of unexpected byproducts. Research labs use our 2-Nitrophenol in enzyme assays, where even scent contamination can throw off results. There’s no substitute for reliability here, and we take those standards personally, having had enough of our own failed experiments early on to appreciate what matters to the people ordering from us today.
Our technical staff has logged thousands of hours not just in making 2-Nitrophenol, but in troubleshooting problem batches. We know where shortcuts lead―off-flavors, odd melting points, hard-to-filter slurries, you name it. We produce several models tailored to actual customers, not imaginary use cases. For dye manufacturers, we offer a grade with purity certified above 99.5%, less than 0.1% moisture, and metal content below 10 ppm. Labs working on analytical chemistry value our ultra-pure grade, which we double-check for possible isomeric overlap. For bulk users, we make a standard-grade 2-Nitrophenol fitting broader industrial processes, where batch-to-batch reliability means the equipment runs without surprises rather than achieving marginally higher purity. Sometimes, projects need a custom solution—specific particle sizes, specialized purity, or unique documentation. Our team has developed custom isolations and purification protocols over the years exactly for these moments, and we’re never shy about learning from customers when their feedback spots something routine testing missed.
Plenty of newcomers ask why not just use 4-Nitrophenol or a technical mixture of nitrophenols if the price looks lower. Here’s the inside reality: The isomer matters in both chemical reactivity and practical outcomes. In color chemistry, ortho- and para-nitrophenol deliver different hue strengths and stabilities, so a “mixed” grade means a finished product that’s unpredictable. 2-Nitrophenol, the ortho variant, features hydrogen bonding that sets it apart in both reactivity and physical properties like the melting point and solubility. In pharmaceutical intermediates, regulators inspect both the content and trace presence of isomers because even slight cross-contamination changes downstream pharmacokinetics. Our facilities separate 2-Nitrophenol fraction by fraction. We’ve optimized distillation and monitored chromatography for each lot—tried, failed, and refined testing over years rather than weeks. It’s why when a customer describes a failed lab run with off-spec p-nitrophenol, we can often pinpoint the cause from experience on the ground, not just theoretical knowledge. This is what “manufacturer expertise” actually offers—the ability to tell where the line between acceptable and exceptional falls, with skin in the game.
We’ve seen supply chain shocks, swings in raw material prices, and even regulatory shifts that change what can or can’t go into processes. Each time, adaptation is our way forward. Take raw material availability. Phenol pricing spikes, and suddenly the entire cost structure for nitrophenols gets pushed upward. We started multi-vendor sourcing long ago and invested in local capacity for basic upstream chemicals. Instead of waiting for market prices to return to “normal,” we put effort into steady supply and showcased this to customers. Unexpectedly, this paid off again during export bottlenecks when others struggled to fulfill contracts. Another issue—shipping hazardous materials in changing regulatory environments. We keep compliance records up to date and maintain our own packaging station, rather than outsourcing. This way, packaging fits requirements for safe transport, reduces breakage, and passes inspections without delay. We also run recurrent in-house training for our warehouse and logistics teams on handling nitrophenol safely—grounded in daily practice, not just clipboard checklists.
There’s a difference between technical paperwork and practical, on-the-ground assurance. You can list purity on a certificate, but unless the production system actually delivers milligram-level consistency, that paper means little in the hands of a working chemist. Over years, we designed batch tracking, run double-verification on analytical data, and keep retained samples from each lot for at least two years. We view complaints and returns as part of the business, not an inconvenience. Often, a returned batch leads to process improvements that benefit every future customer. Sometimes, this means shutting down a production run mid-way after seeing unexpected behavior in a reactor or a slight deviation in color or smell. Cutting corners for “one bad lot” gets noticed in the community—many buyers remember who solved their problem and who ignored it. In the end, the trust built through these hard-won lessons underpins long-term relationships. More than a decade in, some of our oldest clients still call directly, knowing we’ll give a straight answer—for better or worse—based on what we know from making the stuff ourselves.
Every chemist knows the hazards built into nitrophenol production. Leaks, spills, and emissions don’t just hurt the plant—they can cause headaches with regulators, neighbors, and our own staff. For 2-Nitrophenol, we engineered zero-discharge waste management into our processes. Waste acids are neutralized and scrubbed. Workers suit up in protective gear, and we monitor air and water quality at every working station. None of this happens because of external pressure alone; the people running our reactors have friends and families nearby, so “acceptable” exposures on paper rarely cut it in real life. We switch out old process lines, run regular safety drills, and keep visible documentation for every major modification. Years ago, a mistake on the night shift led to a minor leak. Rather than issuing a memo and hoping for the best, we invited all line workers to help redesign that part of the system. The result: Fewer incidents, higher throughput, and direct buy-in from every operator. Anyone who claims safety can be left up to management has not spent time inside a functioning chemical plant.
We don’t hold back knowledge from the teams who rely on it daily. Years ago, we ran headlong into patent disputes when big players began shaking up the market with new application routes for 2-Nitrophenol. We’ve learned to adapt our process where necessary and keep updated on both local and international regulations. That involvement in patent landscape isn’t just legal housekeeping; it gives our technical and sales staff an edge in advising customers about what they're really buying and where risks may exist. We join industry working groups, share data with academic partners, and continually refine our protocol for purity based on peer-reviewed findings. Every time a research paper surfaces describing a failed 2-Nitrophenol synthesis from a questionable source, we compare our data. Openness about strengths and weaknesses stands us in better stead for long-term partnerships than keeping everything locked down. If a customer wants a walk-through of our quality controls, we invite them. Trust builds one candid conversation at a time, not through glossy brochures or generic safety statements.
Real people power these operations. Our chemical engineers and operators come from a range of backgrounds—some learned on the job, others honed skills at universities or in small local companies before joining us. Skill transfer happens over lunches, hands-on training, and sometimes through necessary mistakes that prompt hard lessons. We hold sessions where operators detail process bottlenecks or show new hires how small temperature changes in the reactor impact the color and purity of 2-Nitrophenol. Everyone from plant manager to line worker can recall “problem batches.” Each of these moments led to pushing our standards forward—practical knowledge rooted in lived experience, not abstractions from a textbook. Our story includes supporting first-generation college graduates progressing through the ranks—proving that chemical manufacturing, for all its technical demands, thrives thanks to open doors and shared commitment. This side of the business rarely makes headlines but shapes every metric that matters.
We talk daily with chemists, business owners, and logistics teams who order our 2-Nitrophenol. Speed isn’t the only concern; they want honest timelines, straight talk about raw material delays, and a real person who responds when problems arise. Our feedback loop starts at customer service and stretches all the way back to production planner. If there’s an issue—be it a delayed truck, questions about melting point, or application recommendations—we believe in immediate, transparent communication. Our return rate remains low due to direct ownership from each department. We ask for (and actually listen to) feedback—whether it comes in as email, phone call, or an old-fashioned note in a shipment box. Not everything gets solved the same day, but everything gets addressed. The best lessons sometimes come from an unexpected failure—a batch that caked during transit or an order that passed lab tests but disappointed in field application. Each situation adds to the reservoir of experience. Over time, patterns emerge that refine not just the quality of the product but the predictability of working with us.
Moving 2-Nitrophenol from plant to client remains a challenge, especially across borders. We store fresh product in climate-controlled areas, fill containers with gloves and dust masks, and label each drum or bag with strict traceability. Our trained staff adapts packaging based on customer feedback—some want small jars for lab use, while others require drums that hold up to weeks of ocean freight. Shipping regulations change frequently, and we keep up by continuous training and process updates. Years of experience taught us the importance of contingency planning—a shipment stuck in port due to incomplete paperwork can mean days of downtime for our customer. We work with reliable logistics partners, but always check and recheck documentation before release. When new regulations hit, we update procedures rather than waiting for someone to flag an issue downstream. Keeping complaints rare comes from being present at every handoff—not simply relying on paperwork moving through the chain.
The chemical landscape doesn’t stand still. Research demands ever-tighter tolerances and new derivatives, while industry seeks both cost efficiency and reliability. More jurisdictions tighten their standards around environmental emissions and acceptable impurity levels. We invest in R&D both to improve process yield and to meet tougher regulatory targets. On the ground, this looks like incremental changes—upgrading reactors with tighter temperature control, selecting catalysts that cut residual content, and adopting closed-loop handling to minimize operator exposure. These practices started as solutions to internal challenges but now serve as selling points for discerning customers. We collaborate with buyers to keep applications “downstream safe”—whether they’re developing sensitive assays or scaling up dye production. Regulation isn’t a threat to our operations but an ongoing call to step up quality controls and offer better documentation, not just for auditors but for every user that places value on reliability and traceability in their supply chain.
Years in the business teach that manufacturing 2-Nitrophenol means more than shipping chemicals—it’s about building trust, staying vigilant to risks, and supporting those who move science and industry forward. Today’s 2-Nitrophenol buyers demand more than technical specs. They watch for consistency, transparency, and problem-solving. We stand behind every shipment, shaped by lessons learned on the line, in the lab, and from the voices of hundreds of customers. Our commitment doesn’t rest on slogans or certificates, but on daily choices driven by knowledge, experience, and pride in making a difference in a world that relies, often unnoticed, on the backbone of real chemical manufacturing.