2-Methylaniline

    • Product Name: 2-Methylaniline
    • Alias: o-Toluidine
    • Einecs: 202-440-0
    • Mininmum Order: 1 g
    • Factroy Site: Yudu County, Ganzhou, Jiangxi, China
    • Price Inquiry: admin@ascent-chem.com
    • Manufacturer: Ascent Petrochem Holdings Co., Limited
    • CONTACT NOW
    Specifications

    HS Code

    472617

    Chemical Name 2-Methylaniline
    Other Names o-Toluidine
    Molecular Formula C7H9N
    Molar Mass 107.15 g/mol
    Appearance Colorless to pale yellow liquid
    Odor Aromatic, aniline-like
    Melting Point -16 °C
    Boiling Point 199 °C
    Density 1.00 g/cm³ at 20 °C
    Solubility In Water Slightly soluble
    Flash Point 87 °C (closed cup)
    Cas Number 95-53-4
    Refractive Index 1.579 at 20 °C

    As an accredited 2-Methylaniline factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Amber glass bottle, 500 mL, tightly sealed with a screw cap, hazard labels for flammable and toxic substances, and chemical identification.
    Shipping 2-Methylaniline should be shipped in tightly sealed containers, clearly labeled, and compliant with hazardous materials regulations. It must be kept away from sources of ignition and oxidizing agents. Shipping requires appropriate documentation and use of certified carriers, with precautions to prevent leakage or spills to ensure safe transportation and handling.
    Storage 2-Methylaniline should be stored in a tightly closed container in a cool, dry, well-ventilated area, away from direct sunlight, heat sources, and ignition sources. Keep it separate from oxidizing agents, acids, and strong bases. Use corrosion-resistant containers and secondary containment to prevent leaks. Proper labeling and secure storage are essential to minimize accidental exposure and environmental contamination.
    Application of 2-Methylaniline

    Applications of 2-Methylaniline in Industrial Manufacturing

    2-Methylaniline, also known as o-toluidine, is a crucial aromatic amine deployed as an intermediate in several specialized manufacturing routes. Our direct-to-factory quality management and vertical integration enable us to meet the nuanced needs of downstream producers engaged in value-added chemistry. Below are the primary sectors with real, mature demand for 2-methylaniline as a key input.

    1. Azo Dye Synthesis for Textile Dyeing

    Textile dye manufacturers use 2-methylaniline as a coupling component in the synthesis of vivid azo dyes, particularly for reddish and yellowish shades. Its ortho-methyl group increases the shade strength and lightfastness demanded by modern synthetic fiber and cotton processors. The amine reacts with aromatic diazonium salts during batch or continuous dye manufacturing, integrating tightly into their coloration formulations.

    Industry compliance standards

    • OEKO-TEX® Standard 100 (limit for aromatic amines)
    • ZDHC MRSL (Zero Discharge of Hazardous Chemicals, amine class)
    • EU REACH Regulation (EC) No 1907/2006
    • ISO 105-C06 (Colour fastness to domestic and commercial laundering)

    Typical usage ratio

    • 2-7% based on total dye batch weight, adjusted according to the chromophore system and depth of shade required by the client

    Downstream process integration

    • Feeds directly into the azo coupling phase after diazotization, often in a closed batch reactor under ice cooling to control reaction rate

    Final product types

    • Azo-based disperse dyes
    • Reactive dyes for cellulose and synthetic fibers
    • Direct yellow and red dyes for printer inks and textiles

    2. Rubber Chemical Manufacturing

    2-Methylaniline serves as a precursor for production of vulcanization accelerators, especially MBT (2-Mercaptobenzothiazole) derivatives, applied across tire and industrial rubber fabrication. Using high-purity o-toluidine enables precise control of accelerator functionality and minimizes off-odor and reversion during rubber curing. It enters the supply chain where aromatic amine chemistry underpins the crosslinking additive network.

    Industry compliance standards

    • ISO 9001:2015 (quality management for chemical intermediates)
    • ASTM D3182 (Standard practice for rubber—compounding materials)
    • EU REACH restrictions for PAHs and aromatic amines in elastomers
    • Automotive OEM substance standards (e.g., VW 50180)

    Typical usage ratio

    • 3-10% in intermediate accelerator synthesis, tuned to sulfur curing system and desired crosslink density

    Downstream process integration

    • Undergoes condensation and cyclization reactions, then advanced to vulcanization accelerator formation prior to compounding with rubber masterbatches

    Final product types

    • MBT-based accelerators
    • Pre-dispersed accelerator pellets for tire compounding
    • Elastomer chemical masterbatches
    • High-performance rubber hoses and gaskets

    3. Agricultural Chemical Precursors

    Producers of select pesticide actives and herbicides utilize 2-methylaniline in the formation of substituted anilide and carbamate frameworks. Specific aryl amides synthesized via acylation of this amine provide tailored selectivity and degradation rates, vital for modern crop protection products. This application requires traceable sourcing to satisfy agricultural and environmental regulatory checks from input chemicals onward.

    Industry compliance standards

    • FAO/WHO Joint Meeting on Pesticide Specifications (JMPS)
    • U.S. EPA 40 CFR Part 180 (tolerance levels for pesticidal ingredients)
    • Good Manufacturing Practice for Agrochemicals (FAO)
    • China’s GB 2763 MRLs (Maximum Residue Limits for agricultural inputs)

    Typical usage ratio

    • 5-12% of total synthesis charge, varying by anilide moiety and active ingredient yield requirements

    Downstream process integration

    • Acylated or carbamoylated in closed reactors, feeding into final esterification or formulation steps before granulation or emulsion concentrate blending

    Final product types

    • Pre- and post-emergence herbicides
    • Pesticidal active intermediates (e.g., toluidine-based phenylureas)
    • Selective insecticide actives
    • Agrochemical technical grade concentrates

    4. Specialty Pharmaceutical Intermediate Synthesis

    Pharmaceutical ingredient manufacturers adopt 2-methylaniline in small- and large-scale synthesis of certain APIs, where the ortho-toluidine core forms part of advanced synthetic intermediates. Targeted hydrogenation and acylation reactions involving o-toluidine enable access to antihistaminic or local anesthetic scaffolds, meeting stringent pharmacopoeial purity and traceability demands throughout the supply chain.

    Industry compliance standards

    • ICH Q7 GMP (Active Pharmaceutical Ingredient guidelines)
    • United States Pharmacopeia (USP)
    • European Pharmacopoeia (EP)
    • China Pharmacopoeia (ChP, for domestic manufacturing)

    Typical usage ratio

    • 1-8% depending on stage of intermediate formation and specific synthetic route designed by the downstream API/formulation expert

    Downstream process integration

    • Condensation and further derivatization in multi-step batch reactors, followed by crystallization and purification for conversion to active or protected pharmaceutical intermediates

    Final product types

    • API intermediate compounds for antihistamines
    • Amide or acylated intermediates for local anesthetic API synthesis
    • Laboratory research chemicals under cGMP
    • Advanced pharmaceutical building blocks

    5. Photographic and Imaging Chemical Production

    Producers of color photographic developers and imaging chemicals leverage 2-methylaniline’s electron-donating amine group in the synthesis of couplers and diazo compounds, crucial for high-stability photographic films. Its use in color developer manufacturing demands rigorous batch purity, as trace impurities may affect end-image clarity and fading resistance under archival storage standards.

    Industry compliance standards

    • ISO 18901:2010 (Imaging materials—Process control in photography)
    • ANSI IT9.2 (Stability of color photographic images)
    • EU CLP Regulation (Classification, Labelling and Packaging of substances)
    • Japanese Industrial Standard JIS K 5600

    Typical usage ratio

    • 1.5-6% within developer or coupler synthesis formulations; process engineers determine percentage by coupler structure and batch volume

    Downstream process integration

    • Diazotizes and couples with phenolic substrates during developer production; integrated pre-emulsification step to ensure homogeneity prior to blending or casting

    Final product types

    • Photographic couplers for color film
    • Specialty color developers
    • Archival imaging processing solutions
    • Inkjet imaging chemical blends

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    Certification & Compliance
    More Introduction

    2-Methylaniline: Supporting High-Performance Chemical Synthesis

    Understanding 2-Methylaniline’s Role from a Manufacturer’s Viewpoint

    In the world of chemical manufacturing, there are workhorses that quietly deliver value in every batch and reaction. 2-Methylaniline, also known as o-toluidine, has earned its place at the foundation of many chemical syntheses. Unlike more exotic molecules, 2-Methylaniline proves, time and again, that reliability, purity, and predictable behavior matter most to end users. Every day, we produce this compound in industrial volumes, observing its unique characteristics on a practical scale that only comes with direct experience at the manufacturing level.

    A Close Look at the Product

    Our 2-Methylaniline comes as a pale yellow to light brown liquid, which develops a distinctive aromatic amine scent during handling. The boiling point falls near the 200°C mark, and with each lot, we keep water content and byproduct levels under tight control. Chemically speaking, our product aligns with C7H9N, but real-world users often ask about what’s not in the drum — byproducts, color bodies, or trace metals won’t pass quality control here.

    Every batch runs through our refined distillation train and analytical methods, with gas chromatography confirming the main peak of o-toluidine at no less than 99.5% area. We see customer demand for extremely low aromatics and metallic content, especially from dye and agrochemical producers. This focus doesn’t come from lab theory, but stems from countless stories relayed to us by plant operators and R&D groups who report that even small impurities can throw a downstream process off balance.

    How 2-Methylaniline Powers Industry

    Two primary uses dominate the history and future of this molecule. Its largest role takes shape in the dye industry, where it becomes the feedstock for azo dye intermediates. Every batch of dye intermediates tells its own story on the production floor — fluctuations in color and solubility often track back to the quality of 2-Methylaniline upstream. In our line, we see dye makers requesting repeat analytical proof of trace-level purity, where off-odors or color can mean hours of lost productivity.

    The second major application covers the synthesis of pesticides and pharmaceuticals. Laboratories and production plants convert 2-Methylaniline to acetanilides, sulfonamides, and other specialty compounds. Our formulation teams stay in touch with process engineers from global crop protection and drug manufacturers, who stress that high-purity 2-Methylaniline reduces batch reprocessing and brings cost savings over the long run. Overlooking quality in this intermediate can undermine multi-ton campaigns or, worse, leave downstream synthesis with unexpected reagent costs or compliance hurdles.

    Beyond these primary applications, the rubber and photographic industries use this compound to produce accelerators and colorants. On each occasion, end users relay their requirements directly — whether it concerns oxidative stability, shipping container material, or handling guidance. We see that standard plastic drums sometimes leach unwanted organics into sensitive amine batches, especially under elevated temperatures. So, we adapted our filling lines to include all-metal drums when a client requests uncompromised batch integrity.

    Production Scale Effects: From Pilot to Bulk

    Lab syntheses rarely reveal some truths about scaling up. In small flasks, impurities or handling quirks can go unnoticed. Once you scale up to truckload production, new realities show up. Our teams observe this especially during amination, where iron catalysts, temperature swings, and water content can tip a reaction in less than an hour. Over time, in our plant, we tuned our process setpoints and raw material feed controls to keep color, acidity, and residual starting material below customer acceptance standards.

    Yield also takes on a different meaning at our scale. Operating continuously means that process interruptions or contamination in a single feed tank create not just downtime, but knock-on effects across multiple customer orders. We invest where it makes the biggest difference in throughput: real-time monitoring, well-calibrated distillation columns, and rigorous drum cleaning and drying. Our operators take pride in delivering containers that consistently open to that familiar faintly sweet, characteristic o-toluidine odor instead of anything unexpected.

    What Sets This Compound Apart from Others

    Industry users often compare 2-Methylaniline with aniline and its other methylated isomers. Differences come down not just to position — our product carries a methyl group at the ortho location to the amine, which slightly changes both reactivity and toxicity. This o-methyl orientation makes it particularly valuable for synthesizing intermediate dyes and pesticides, granting it an edge where selectivity or chain extension begins with that position.

    Aniline is cheaper by weight and widely used. In our experience, customers who upgrade to 2-Methylaniline do so because the substituent position lets downstream reactions proceed at milder conditions or produce a cleaner, easier-to-purify product. This influences not just cost-of-goods but sometimes product registration and validation, especially in the pharmaceutical sector, where each impurity profile must be documented and defended.

    We also see that m-Toluidine and p-Toluidine exist for other niche purposes, but demand for the ortho isomer stands out among pigment and agricultural chemical producers. For these users, technical support often involves in-depth discussions about isomer separation, anticipated color body formation, or even storage duration’s effect on the main amine peak.

    Staying Power and Handling in Production

    Aromatic amines, by their nature, require careful handling. Each drum gets filled under inert atmosphere, and sample taking happens only after decontaminated sample ports confirm that air has not contacted the liquid phase. Our long-term experience reveals that even a few hours of air exposure at summer temperatures can change the color from pale yellow to deep brown. Once that happens, some customers notice failures during sensitive downstream reactions. So, we regularly counsel storage and handling improvements — seamless steel drums, nitrogen padding, and rapid throughput from delivery to reactor feed.

    On occasion, customers transporting the product over very long distances or leaving it on the dock through weather swings come back with complaints about unusual odor or color. Open communication helps us quickly source the root cause and teach best practices for handling. We’re always aiming for feedback loops. Troubleshooting usually means circulating updated storage specs, holding regular training with logistics partners, and in-plant visits from our technical team if required.

    Listening to Product End Users

    Manufacturing does not end at the reactor. We spend time talking to the operators, product development chemists, and purchasing teams who build entire businesses around stable, high-quality feedstocks. 2-Methylaniline is not a flashy molecule, but end users quickly notice even the smallest mishap in purity or handling. Over years, we’ve learned as much from handling feedback as from any textbook — details such as preferred drum size, time to unload, and required shelf life shape the way we design our production and packaging.

    In one case, a specialty dye maker identified a recurring off-color in their end product. By collaborating closely with their QC team and sharing retention samples from our own storage, we isolated a subtle oxidation mechanism that happened during cross-continent shipping. The learning? Sometimes, even small tweaks in fill head design or tighter drum wall thickness mean less exposure and fewer headaches.

    Unlike some intermediates that tolerate rough handling, 2-Methylaniline rewards careful logistics. Just a bit of extra temperature during loading means increased vapor pressure and a higher chance of container sweating. So, our facilities use climate-controlled storage, and our logistics group tracks every pallet from filling line to delivery bay, minimizing wait times and variances that could degrade the batch. Where customers need very fine cut points for sensitive formulations, they turn to us for custom packaging or just-in-time delivery, and we work out those solutions together.

    Quality Assurance Rooted in Experience

    Some of the most important lessons on quality didn’t arrive from formal audits or third-party checks, but from our own teams solving day-to-day production challenges. Spectrophotometry and chromatography play their role, of course, but visual inspection, drum odor sampling, and periodic user feedback close the loop. Each QA operator knows the end uses are unforgiving—especially where brightly colored dyes, precision drug molecules, or highly pure pesticides depend on this one step in the manufacturing chain.

    We take pride in sharing complete, traceable documentation with each lot and encouraging open dialog when users spot something new or unexpected. Batch-to-batch reproducibility has become our mantra, and our technical support staff treat anomalies not as routine complaints but opportunities to track a cause, adjust an SOP, or alert our raw material suppliers. Sometimes, this means halting a shift and reprocessing material before it leaves our gate.

    As producers, not traders, we stake our reputation on long-term relationships and full responsibility for the product as it moves through the value chain. From the reaction kettle to the distribution drum, every step receives human attention, as laboratory workflows only go so far without hands-on vigilance and pride in the finished result.

    Balancing Safety, Sustainability, and Scale

    Responsibility in chemical production means understanding both the benefit and the inherent risks. 2-Methylaniline carries known hazards as an aromatic amine, requiring engineered controls and thorough protective procedures for every member of our team. We set facility ventilation, capture vapor emissions, and run annual health screenings for team safety, not just after an incident but as ongoing routine.

    Over the past decade, our process development group has also sought to reduce waste and avoid off-spec byproducts that might enter the effluent system. Our transition from batch to continuous process control marked a turning point in both operator safety and product consistency. Less exposure to oxygen, faster throughput, and more regular sample intervals dropped emissions and cut down on rework, saving both energy and raw material.

    We also listen to the shifting requirements of customers seeking green chemistry solutions. Queries about renewable feedstocks have become more common, especially from multinational buyers. While petroleum-based routes remain standard today, we continue monitoring alternative benzene derivatization methods, and we participate in industry workgroups focused on both process and supply chain sustainability.

    Ongoing Product Improvement and Solutions for Common Challenges

    The cycle of product improvement never stops. As the market evolves, and as end uses become more demanding, our technical and production teams stay in contact with customers about new challenges and ways to address them. Some dye producers now require ultra-low trace amine content; the batch-by-batch feedback we get fuels new investment in inline purification columns and closer integration between reactors and QC labs.

    Packaging improvements, such as wider range drum linings and advanced gas barriers, provide solutions for those shipping to climates that previously led to off-spec shipments. Meanwhile, customers who move toward continuous synthesis appreciate the ability to source large, uniform lots with matched impurity profiles. These changes are not cosmetic; they reduce downtime, support tighter regulatory filings, and help avoid compliance headaches.

    We exchange best practices with both peers and external experts. For example, our team collaborates with fire safety advisors and logistics planners to keep hazardous goods protocols current and practical. We also work with academic groups and consortia to benchmark new synthetic methods as they emerge, aiming to spot potential shifts in global regulatory requirements before they reach full enforcement.

    Practical Value through Direct Manufacturing

    Years of handling, producing, and delivering 2-Methylaniline teach lessons that can’t be found in data sheets. Our plant workers know almost instinctively how a drum should smell, the typical color range, and how to fix a contaminated batch before it reaches the dock. Relationships with end users go far deeper than spot purchases — often spanning decades, with shared troubleshooting on color stability, impurity drift, storage conditions, or even formulation compatibility.

    For those who count on every drum of o-toluidine to behave predictably in scaling up their own operations, the difference between a direct producer and a third-party trader matters. We track raw material origins, process deviations, and even the tiniest changes in lab readings. These practical steps result in better insight if a downstream process starts to misbehave. We build processes not just to order, but guided by the collective feedback of thousands of applications and years of hard-earned know-how.

    Conclusion: Confidence Gained from Hands-on Manufacturing

    Delivering 2-Methylaniline into demanding markets means much more than shipping a chemical by the ton. It requires intensive process control, a deep respect for the requirements of users, and the sort of reliability that only comes from years behind the reactor and inside the drum-filling hall. Every success story with dyes, drugs, or agricultural chemicals that starts with a clean batch of o-toluidine represents the cumulative effort of hundreds of hands and eyes, each dedicated to making sure that every minor detail is paid attention to. Those who know the production realities, and the difference between a well-made and hastily sourced batch, understand the unspoken value in chemical manufacturing — and that’s the reliability and partnership our users count on every day.

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