|
HS Code |
120033 |
| Chemical Name | 2-Methyl-4,6-Dinitrophenol |
| Cas Number | 534-52-1 |
| Molecular Formula | C7H6N2O5 |
| Molecular Weight | 198.14 |
| Appearance | Yellow crystalline powder |
| Melting Point | 108-110 °C |
| Boiling Point | 354.3 °C at 760 mmHg |
| Solubility In Water | Slightly soluble |
| Density | 1.57 g/cm³ |
| Pubchem Cid | 86252 |
| Synonyms | DNOC, Dinitro-o-cresol |
| Flash Point | 193.6 °C |
| Logp | 2.32 |
| Inchi Key | XQSAKJMEFAPJMO-UHFFFAOYSA-N |
| Ec Number | 208-591-8 |
As an accredited 2-Methyl-4,6-Dinitrophenol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | Amber glass bottle containing 100 grams of 2-Methyl-4,6-Dinitrophenol, tightly sealed, labeled with hazard warnings and chemical specifications. |
| Shipping | 2-Methyl-4,6-Dinitrophenol must be shipped in compliance with hazardous materials regulations, as it is toxic and potentially explosive. Use tightly sealed, chemically resistant containers with appropriate labeling. Transport requires strong outer packaging, protection from heat, and documentation per local and international guidelines, such as UN transport codes and Safety Data Sheets (SDS). |
| Storage | **2-Methyl-4,6-Dinitrophenol** should be stored in a cool, dry, well-ventilated area away from sources of ignition and incompatible substances such as strong reducing agents and combustibles. Keep the container tightly closed and protected from light. Use explosion-proof equipment and ground containers. Store away from heat, sparks, and open flames to prevent fire or explosion risk due to its combustible nature. |
Applications of 2-Methyl-4,6-Dinitrophenol in Industrial Manufacturing2-Methyl-4,6-Dinitrophenol serves as a specialized intermediate in industrial chemistry, participating in well-established sectors where rigorous process control and compliance are required. Below, we outline the main downstream application scenarios with concrete process, compliance, and end-use detail based on direct manufacturing experience. 1. Agrochemical Intermediate SynthesisThis compound acts as a critical nitroaromatic precursor during the synthesis of selective herbicides and insecticides, particularly for triazole and phenoxy-carboxylic acid families. Manufacturers integrate it at the nitration or amination stage to enhance biological activity of target actives. Its controlled reactivity makes it essential for consistent batch yields and meets stringent trace impurity limits set by agrochemical quality requirements. Industry compliance standards
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2. Dye and Pigment Manufacture2-Methyl-4,6-Dinitrophenol functions as a colorant intermediate in the synthesis of specialized azo dyes and pigment lakes for textiles, leather, and plastics applications. Producers value it for its nitro group contribution to shade intensity and dye fastness, especially in acid-dye and disperse-dye lines where molecular modification offers targeted color range extension while maintaining process purity. Industry compliance standards
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3. Photographic Chemical ProductionAs a key organic intermediate, 2-Methyl-4,6-Dinitrophenol is used in the manufacture of color couplers, developers, and image stabilizers within silver halide photographic film and paper production. Its electron-withdrawing properties enhance image development chemistry, ensuring precise reaction kinetics necessary for high-resolution imaging while keeping by-product formation within analytic control limits for sensitive emulsion systems. Industry compliance standards
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4. Pharmaceutical Intermediate for Specific API SynthesisThis nitrophenol derivative finds application as a controlled intermediate in multistep synthesis of certain Active Pharmaceutical Ingredients (APIs), especially where aromatic nitration is required for forming bioactive scaffolds. Pharmaceutical manufacturers avoid direct nitroaromatic group introduction during late stage synthesis; thus, pre-manufactured intermediates using this compound help to optimize yield and maintain batch-to-batch consistency under global GMP frameworks. Industry compliance standards
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5. Polymer Additive and Modifier ManufacturingThe compound is incorporated as an additive in certain engineering plastics to impart UV-absorption or to function as a chain modifier in high-performance polymerization. Its chemical structure aids in tailoring the photo-stability or processability profiles in specialty plastics, with quality checks for migration and residual monomer content throughout the compounding steps. Industry compliance standards
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Every day on the plant floor, decisions around 2-Methyl-4,6-Dinitrophenol start with understanding its core purpose and performance. This isn’t just another entry on a chemical catalog. The substance’s clean yellow crystalline appearance reflects a precise synthesis pathway and careful quality controls. What matters most in our production isn’t just getting a batch out the door, but achieving high consistency in purity and handling properties to support industrial use.
Over the years, engineers and chemists here have worked out dense process flows where control of raw materials and reaction conditions stay tight at every step. In our controlled lines, we produce 2-Methyl-4,6-Dinitrophenol using established routes that ensure repeatability. Many of our customers require product at a purity higher than 98%. We frequently reach that, but we keep testing, adjusting, and benchmarking against previous runs. A solid melt point with reliable spectral signatures in every batch means less troubleshooting later.
We don’t rely on generic, broad specifications. Our analytical chemists use real-world calibration, not old tables. Spectroscopy, chromatography, and regular spot checks keep every run inside customer margins. Even small shifts in moisture or incomplete nitration show up fast—we catch those so users don’t have to.
In our experience, most demand for 2-Methyl-4,6-Dinitrophenol comes from dye intermediate synthesis, research, and sometimes specialty energetic formulations. Each user values its electron-withdrawing groups, which tune molecule reactivity for subsequent steps—especially nitro and methyl on the phenolic ring. Because of our fine control over these substituents, industrial chemists can push yields a bit higher and reduce their waste when they build on this core.
Several customers in the interfacial polymer and pigment sectors select this compound because it threads a line between strong electron demand and moderate acidity. Unlike parent dinitrophenol or simple dinitrobenzenes, the methyl group provides a handle for further functionalization, which sets up more complex target molecules. This matters in applications where standard dinitrophenols fall short in selectivity or solubility. We’ve had conversations with researchers who appreciate what looks like a small tweak—the methyl group—for its sizable impact on enzyme inhibition studies, redox behavior, and aromatic substitution possibilities.
On paper, 2-Methyl-4,6-Dinitrophenol often lands in lists under “chemical intermediates” or “reductive dye precursors.” That phrase only scratches the surface. We have watched experienced process chemists pick this compound because it helps manage reaction rates where selectivity matters. In the dye sector, consistency in nitro substitution ensures fewer reprocessing cycles later, especially for high-fidelity yellow and orange shades. For labs optimizing for specialty applications, predictable reaction outcome saves time and resources.
Equipment operators here know the material granularity and flow are just as critical, as these affect mixing and dissolution rates. We maintain strict process parameters on particle size during drying and sieving. Customers in continuous processing lines have pointed out that our product moves cleanly through feeders and doesn’t clump in silos—a difference from some imports. That smooth flow translates to fewer maintenance stops.
Performance with this chemical starts with reproducibility. We’ve spent many years dialing in routines to hold batch-to-batch variation to tight tolerances—on color, melting behavior, and residual solvents. For users running scale-ups or regular campaigns, deviation in particle quality or reactivity means lost hours and wasted reagents. We run every shipment past our in-lab reference standards, not just paperwork reviews. Spectra, chromatograms, and impurity analyses go with every outgoing lot.
On one of our recent reviews, we identified sub-percentage-level differences in a lot by direct side-by-side NMR with an internal reference. None of those details get glossed over in our release logs. Every time we innovate on the upstream purification, we rerun application tests in our on-site pilot lab, measuring how our improvements land for users—solubility in practical solvents, reactiveness in downstream operations, and residue on glassware. This disciplined routine lets us catch the rare off-spec sample before shipment.
A lot of outsiders treat 2-Methyl-4,6-Dinitrophenol just as another dinitrophenol cousin. Chemically, it stands out in several ways. The methyl group at the 2-position changes both the electronic pull and the steric pattern on the ring, which alters how the molecule interacts with bases, nucleophiles, and transition metal catalysts. For synthetic chemists in flavor and fragrance intermediates, this effect can mean cleaner reactions and faster turnovers.
We’ve seen some users grab regular 2,4-dinitrophenol, only to run into solubility walls, redox stability issues, or unexpected side products. The tweak with methylation isn’t cosmetic; it matters for downstream yield and selectivity. The 4,6-nitro substitution offers unique resonance stabilization, unlike the more common 2,4 isomer, and its acidity profile simplifies washing and neutralization steps in recovery. Our experience has shown that this reduces the frequency of rework and solvent wash volumes on industrial lines.
Going past just functional differences, our process brings extra robustness: no off-tint batches, no persistent organic impurities, no unpredictable fines content. We source only high-purity nitric and methylating starting materials, sidestepping common industrial contaminants. Our plant operators catch the difference in both smell and solution color—these checkpoints are hard to fake, and they matter to process engineers stuck with tough quality reviews.
Behind every batch, operators here respect 2-Methyl-4,6-Dinitrophenol for both its utility and its hazards. It remains a powerful irritant and can be acutely toxic with improper handling. Factory routines emphasize protective clothing and closed-system charging whenever possible. Every worker who loads a reactor or samples a dryer has training tailored to the materials at hand. We maintain tight control on airborne dust during packaging and dispatch, cutting down the odds of occupational exposure. Drums are sealed after nitrogen back-purge to exclude airborne moisture and keep material integrity intact.
Buyers from regulated markets often ask about documentation and provenance. We don’t just rely on old COAs but keep real-time logs, including in-process controls and endpoint testing. In some regions, extra regulatory filings apply—our compliance officers review every outgoing batch to keep us in line with current standards. Our stances on safe handling aren’t just legal; they’re built from years of minimizing incidents under real operating conditions.
In the chemistry business, buzzwords pop up fast. Out here, reliability is the factor that separates workable material from headache batches. Every process technician in our building knows the value in samples that pour cleanly, react as they should, and don’t gum up reactors or leave stray residues. Laboratories and plants have called us directly to describe how a slight impurity on a bulk order from another supplier ruined a week’s operation; we take that as a lesson to keep raising our bar.
The market might treat 2-Methyl-4,6-Dinitrophenol as a “commodity,” but anyone who runs real syntheses knows the pitfalls of treating it that way. Process upsets, downstream discoloration, clogs during transfer—these nightmares often trace back to small gaps in quality control upstream. From the very first steps in our process design, the focus rests on points that matter most in live manufacturing: particle size distribution, residual mineral acids, potential for byproduct nitration, and off-odor sources. We design our campaigns for robust downstream compatibility, not just shelf life.
Feedback loops with direct customers help us course-correct when practical issues show up in their new applications. Sometimes, a higher bulk density or a slightly adjusted melt range can improve plant throughput by cutting down on transfer losses. We keep one foot inside our own lab and one in the end-user’s process bay, so our tweaks are always guided by real-world data, not abstract “industry best practices.”
Every year brings different sourcing headaches. Raw ingredient variability pressures costs and sometimes, overall output. Our long-term contracts with upstream suppliers help us weather swings in commodity prices and guarantee traceability at every step. Instead of broad specification sheets that hide margins, we release analytical results with each lot, demonstrating our batch’s performance within real margins that customers care about.
Sometimes, new users with experience in similar compounds expect 2-Methyl-4,6-Dinitrophenol to behave identically. The difference in reactivity, volatility, and environmental behavior can catch a plant off guard. Our technical support team addresses these learning curves, sharing practical guidance rather than textbook theory—optimal solvent selection, filtration strategies, residual risk management, and even recycling techniques for side streams. These approaches don’t just save customers time—they cut unnecessary test runs and anxiety during audits.
One of the most underappreciated differences from other nitrophenol-based alternatives shows up in how 2-Methyl-4,6-Dinitrophenol responds in multi-step syntheses. Precision in methyl group placement creates an aromatic ring more resistant to undesired substitutions. For process chemists looking to control reaction windows or manage downstream functionalization, that difference means fewer side products and higher assay yields. We’ve listened to teams share stories of batch failures using imported off-brand material, wishing they’d traced problems back sooner to small differences in chemical structure and impurity profile.
Our lab’s constant feedback cycle leads to tweaks in drying and packaging. For a material that absorbs moisture or starts to clump under less-than-ideal storage, losses mount fast in plants with automated delivery lines. We’re honest about these risks, offering practical storage and transfer hints to every customer. Regular lab stability checks under local climate conditions—hot, humid summers included—mean fewer surprises no matter where shipments land.
We invest in transparent process logs and open lines with technical teams at customer sites. Rather than sending out faceless bulk shipments, we keep relationships engaged, willing to roll up sleeves and find the root of any process hiccup or color deviation. Those connections often spark upgrades for everyone: we add a drying step; a customer finds a shortcut in dilution; another shares a small instrument tweak that tightens readings.
Regulations shift every few years, along with broader concerns over environmental impact and process safety. We stay hands-on with any new compliance requirements, sending technical documents and procedural updates to downstream users instead of waiting for issues to arise. Most recently, as concerns around persistent organics in water and waste streams have grown, we’ve refined both end-stage purification and effluent strategies, giving users extra assurance that clean-up moves in the right direction.
Process optimization never winds up a one-and-done operation. We offer guidance on practical methods to limit process losses and keep recovery rates sharp. Tighter filtration set-ups, recommendations for solvent blends, and guidance on pH adjustment at key stages come directly from trial-and-error experience in both our own lines and user feedback. In some cases, customers found better throughput after switching feeder systems or altering agitator speed—sometimes, the difference lies in seemingly small choices, but the impact on downtime and overall yield is significant.
On the analytical side, our chemists keep refining protocols for detecting minute byproducts, not just for our sake but for users verifying incoming material. We run comparison checks to catch trace organic salts or metallic residues that can hang up scaling operations. Far from just ticking boxes, this effort means we spot trouble early rather than allowing issues to snowball through multiple production campaigns.
Environmental controls aren’t an afterthought. We’ve cut down on wastewater discharge by optimizing rinsing and limiting the need for solvent-intensive washing, especially after the nitration phase. These adjustments started out for our own compliance but now mean our downstream partners have less to manage or reroute into their own wastewater systems.
Innovation doesn’t always mean a completely new molecule or technology. Here, it often arrives through better waste management, safer handling, and constant refinements in our process parameters. We take feedback from regulatory audits and incorporate direct feedback from operators, not just managers in offices. Ideas come up in morning meetings, sometimes sparked by as little as a technician’s comment about powder flow or an operator’s trick for quicker drum sealing.
For users integrating 2-Methyl-4,6-Dinitrophenol into more complex syntheses or newer fields, we exchange knowledge freely—not as a sales technique, but out of shared interest in what works under fire. Researchers pushing the boundaries of specialty dyes or new energetic compounds reach out with needs for custom cuts on particle size, alternate handling formats, or modified drying profiles. We take these as challenges, running small-scale pilots before scaling up, watching for bottlenecks or contamination risks that wouldn’t show up on a spreadsheet.
Adjustments in material handling, reaction conditions, or purification don’t take effect in a vacuum. We make sure that every tweak filters through both our own QA and customer processes, keeping surprises to a minimum at every link. Adaptability, rather than rigid adherence to legacy practices, keeps our process robust in changing market and regulatory environments.
We keep moving by building partnerships—not just transactions. Clear communication with process chemists, operators, and technical teams generates improvements big and small. When issues come up—unexpected side products, tough-to-remove stains, or shipping delays—we respond directly, sending more than just a standard COA. Feedback cycles help everyone, ensuring that the compound lands smoothly not just in a warehouse, but in live production.
The best outcomes come from sharing knowledge. Our support teams keep in touch long after delivery, checking in not for up-selling, but to trade updates on practical results and field challenges. We take pride in a transparent, traceable manufacturing approach, knowing that reliable chemistry comes from well-understood materials produced by people who take genuine pride in what they do. For us, 2-Methyl-4,6-Dinitrophenol is more than an entry in a database—it’s a testament to steady hands, informed adjustments, and direct dialogue across the supply chain.