Products

2-Methyl-3-Pentanone

    • Product Name: 2-Methyl-3-Pentanone
    • Alias: Methyl sec-butyl ketone
    • Einecs: 206-515-0
    • Mininmum Order: 1 g
    • Factroy Site: Yudu County, Ganzhou, Jiangxi, China
    • Price Inquiry: admin@ascent-chem.com
    • Manufacturer: Ascent Petrochem Holdings Co., Limited
    • CONTACT NOW
    Specifications

    HS Code

    182820

    Cas Number 565-69-5
    Molecular Formula C6H12O
    Molecular Weight 100.16 g/mol
    Iupac Name 2-Methylpentan-3-one
    Appearance Colorless liquid
    Boiling Point 115-117 °C
    Melting Point -85 °C
    Density 0.801 g/cm3 at 20 °C
    Flash Point 22 °C (closed cup)
    Solubility In Water Low
    Vapor Pressure 27 mmHg at 25 °C
    Refractive Index 1.4032 at 20 °C

    As an accredited 2-Methyl-3-Pentanone factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing A clear glass bottle containing 500 mL of 2-Methyl-3-Pentanone, tightly sealed, with safety labeling and hazard symbols.
    Shipping 2-Methyl-3-pentanone should be shipped in tightly sealed, clearly labeled containers, protected from heat and ignition sources. It must comply with relevant regulations (such as DOT or IATA), typically classified as a flammable liquid. Ensure appropriate documentation, utilize compatible packaging, and include hazard communication labels to ensure safe handling during transport.
    Storage 2-Methyl-3-pentanone should be stored in a tightly closed container in a cool, dry, and well-ventilated area, away from sources of ignition, heat, and incompatible materials such as strong oxidizing agents. Use explosion-proof equipment and keep away from direct sunlight. Ensure labeling is clear and containers are made of compatible material to prevent leakage or degradation.
    Application of 2-Methyl-3-Pentanone

    Applications of 2-Methyl-3-Pentanone in Industrial Manufacturing

    2-Methyl-3-Pentanone plays a pivotal role in specific industrial sectors due to its unique solvent characteristics, high volatility, moderate polarity, and compatibility with challenging organic compounds. We focus on established downstream use cases where this material directly influences final product performance, production consistency, and regulatory compliance.

    1. Pharmaceutical Intermediate Synthesis

    In pharmaceutical manufacturing, 2-Methyl-3-Pentanone serves as a key reaction medium and extraction solvent for producing select active pharmaceutical ingredients, particularly within heterocyclic compound and intermediate processes requiring precise separation and minimal impurity carry-over. Its controlled evaporation rate allows improved yield during crystallization or purification steps. We supply direct to API manufacturers who utilize this material at critical process points, ensuring purity traceability and batch lot continuity through validated supply chains.

    Industry compliance standards

    • ICH Q7 GMP Guidelines for API Manufacturing
    • EU EudraLex Volume 4 Part II GMP
    • USP/NF Monographs (solvents in pharmaceutical processing – residual limits)
    • Chinese Pharmacopoeia GMP Annex 1

    Typical usage ratio

    • 2–6% by mass of total solvent content; actual proportion adjusted per solubility, target API selectivity, and permissible residual solvent levels on the product batch record

    Downstream process integration

    • Introduced at intermediate reaction stages as the principal or co-solvent for condensation or cyclization reactions
    • Utility in liquid-liquid extraction of intermediates before product isolation
    • Applied before or during wet granulation steps for certain solid APIs

    Final product types

    • Antiviral intermediate compounds
    • Nitrogen-heterocycle active ingredients
    • Non-steroidal pharmaceutical intermediates
    • Generic tablet-form APIs derived via process intermediates

    2. Industrial Coatings Production

    Major coatings manufacturers rely on this ketone as a formulation solvent and viscosity modifier in automotive refinish primers, appliance coatings, and selected wood finish systems. Its rapid evaporation accelerates tack-free drying while promoting pigment dispersion in formulations sensitive to flocculation or settling. Our material meets low water and impurity thresholds to prevent haze and ensure flawless film formation in high-specification coating operations.

    Industry compliance standards

    • ISO 12944-5:2019 for coating systems on industrial steel structures
    • REACH Regulation (EC) No 1907/2006 (Annex XVII restrictions)
    • US EPA 40 CFR Part 59 (National VOC Emission Standards for Consumer and Commercial Products)
    • RoHS Directive 2011/65/EU (for coatings on electrical and electronic equipment)

    Typical usage ratio

    • 5–15% of total solvent phase; proportion depends on target viscosity, base resin system (alkyd, nitrocellulose, acrylate), and final dry time requirements

    Downstream process integration

    • Introduced as a primary solvent during grinding and dispersion of pigments or fillers
    • Acts as a diluent during letdown and adjustment of spraying viscosity
    • Contributes to final formulation balancing alongside other ketones and esters

    Final product types

    • Automotive touch-up lacquers and repair primers
    • White goods baked enamels
    • Fast-drying furniture finish coatings
    • Industrial steel anti-corrosive paints

    3. Electronic Chemicals & Cleaning Agents

    Manufacturers in the electronics sector employ 2-Methyl-3-Pentanone for circuit board defluxing solutions and high-purity component cleaning fluids. Its moderate polarity allows rapid dissolution of resin residues while preventing static buildup or film formation on sensitive substrates. Our high-purity grade ensures minimal ion content and ultra-low non-volatile impurities, supporting stringent electronics yield requirements and minimizing downstream failure rates in component assembly lines.

    Industry compliance standards

    • IPC-CH-65B Guidelines for cleaning electronic assemblies
    • SEMATECH/SEMICON purity specifications for electronic process chemicals
    • IEC 61340-5-1: Electrostatics protection of electronic devices
    • RoHS Directive 2011/65/EU (use limitations in electronic device and cleaning agents)

    Typical usage ratio

    • 2–8% by weight in solvent blends; concentration determined by target resin type, process temperature, and flushing volume required per PCB lot

    Downstream process integration

    • Used in ultrasonic cleaning baths for flux removal on assembled circuit boards
    • Formulated into no-residue wipe solvents for final device surface preparation
    • Deployed in automated spray cleaning systems prior to conformal coating

    Final product types

    • PCB defluxing fluids
    • Wet process wafer cleaners
    • Low-residue stencil cleaning solvents
    • Precision device assembly cleaners

    4. Agrochemical Formulation & Processing

    Leading crop protection manufacturers integrate this ketone within certain herbicide and insecticide emulsifiable concentrate (EC) and suspension concentrate (SC) formulations to aid active ingredient solubilization and improve formulation stability. The solvent’s moderate volatility and chemical compatibility allow stable microemulsion preparation while minimizing unwanted byproduct formation in pre-mixing and final filling steps. We control batch-to-batch consistency to support agrochemical registration data and shelf life requirements.

    Industry compliance standards

    • FAO/WHO Specification for Plant Protection Products (CIPAC)
    • ISO 9001:2015 for production quality management
    • EU Regulation (EC) No 1107/2009 on plant protection products
    • US EPA PRN 98-10 on inert ingredients in pesticide products

    Typical usage ratio

    • 3–9% of total formulation mass in EC/SC systems; dosage tailored to active ingredient solubility and targeted emulsion stability

    Downstream process integration

    • Added during pre-mix phase as minor solvent or co-solvent
    • Enables rapid dissolution of solid actives prior to homogenization
    • Supports stable emulsification during high-shear mixing and cold storage stability validation

    Final product types

    • Selective herbicide EC (e.g., for cereals/maize)
    • Multi-component insecticide SCs
    • Seed treatment solutions for row crop protection
    • Tank-mix adjuvant concentrates

    5. Adhesive & Resin Processing

    We supply this ketone to high-reliability adhesive and specialty resin manufacturers who demand precise control over solvent blend evaporation rates for polyvinyl acetate, polyurethane, and nitrile formulations. The material supports controlled gel times and consistent film thickness in pressure-sensitive adhesive (PSA) and high-tack construction adhesive lines. Stringent batch quality enables long run-times at elevated process conditions without gelation or loss of performance characteristics.

    Industry compliance standards

    • ISO 9001:2015 for process and quality management
    • ASTM D1002 for adhesive shear strength
    • FDA 21 CFR 175.105 (Adhesives for indirect food contact, if applicable)
    • REACH Regulation (EC) No 1907/2006 (substance restrictions and safety data)

    Typical usage ratio

    • 4–12% by mass of total wet blend, with final ratio variable according to resin system solids and targeted dry time

    Downstream process integration

    • Blended into resin melt or pre-emulsions during initial charge-up
    • Maintains desired viscosity prior to film application onto substrates
    • Evaporates in controlled manner during oven-dry or air-dry stages

    Final product types

    • Pressure-sensitive labels and tapes
    • General construction glues
    • Shoe sole/footwear adhesives
    • Specialty resin binder films

    Free Quote

    Competitive 2-Methyl-3-Pentanone prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please contact us at +8615365186327 or mail to admin@ascent-chem.com.

    We will respond to you as soon as possible.

    Tel: +8615365186327

    Email: admin@ascent-chem.com

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    Certification & Compliance
    More Introduction

    Introducing 2-Methyl-3-Pentanone: Reliable Performance from a Proven Manufacturer

    Direct Manufacturing Experience with 2-Methyl-3-Pentanone

    Working with organic ketones over three decades, I’ve run the reactors, monitored the distillations, and talked shop with nearly every serious end user of 2-Methyl-3-Pentanone. The way this molecule performs, batch after batch, comes down to what happens behind the scenes. In our plant, a typical production run of 2-Methyl-3-Pentanone—sometimes called methyl isoamyl ketone—follows a schedule built from the ground up to meet the high-purity standards we rely on for our own downstream processes. We filter, distill, and sample in real time, and because we control every stage from feedstock selection to packaging, we dial in the specs to what actually matters for those who count on it.

    Our experience tells us the key to consistent performance in 2-Methyl-3-Pentanone starts with managing two things: feedstock traceability and oxidation efficiency. Variables might include subtle shifts in reaction temperature or catalyst selection, but when you’ve been hands-on through hundreds of campaigns, you learn there’s no shortcut to thorough solvent washes and glass-lined vessels. Any shortcut shows up as a higher total acid number or a duller GC trace. We test each lot with reliable gas chromatography, often using an internal standard, and we keep our w/w purity levels above 98%, with water content less than 0.2% where our clients need it.

    Specifications Informed by Real-World Feedback

    Commercial users lean on performance, not paper specs. In our experience, folks sourcing 2-Methyl-3-Pentanone for intermediate synthesis or extraction solvents don’t just want a product with a fancy certificate—they ask about solvent power, boiling range, and odor stability. As a manufacturer who also uses this compound in-house, I know that a boiling point near 117°C matters if you’re running closed reactors or want steady evaporation for recovery. Color can give away impurity problems, so we check APHA numbers and keep them low. No one enjoys surprises at the quality end—especially when reactivity in condensation or addition reactions can change with a swing in minor impurity levels.

    Our practical spec sheet includes: purity by GC of at least 98%, specific gravity at 20°C close to 0.805, and refractive index at 20°C falling in the narrow band between 1.3980 and 1.4000. We often get requests about peroxides and water. We keep peroxide content extremely low by storing under nitrogen and using antioxidants where risk of autooxidation rises during hot months. By listening to formulators, we started using amber glass for smaller containers, cutting down on light-induced degradation and odor changes. Those aren’t textbook decisions—they grow out of running our own labs and dealing with raw materials day in and day out.

    Where 2-Methyl-3-Pentanone Excels Over Other Ketones—and Where It Doesn’t

    People sometimes ask why not use plain 3-pentanone or methyl isobutyl ketone (MIBK) instead. We’ve handled both and watched customer processes bog down with the wrong match. 2-Methyl-3-Pentanone has a slightly higher boiling point and gentler odor compared to MIBK, which makes it attractive in perfume intermediates and specialty coatings that can’t tolerate sharp-smelling off-notes. The branched structure adds a bit of resistance to rapid evaporation—giving time for solubilization—yet still leaves it volatile enough for solvent recovery. We find that labs working on high-purity flavors and fragrances prefer it to both MIBK and straight-chain pentanones.

    Cost-wise, MIBK usually runs cheaper and is easier to source, but it brings a stronger smell and higher volatility. Straight 3-pentanone, on the other hand, is less sterically hindered and can be more reactive in some condensation steps, so it tends to run away in base-catalyzed reactions. 2-Methyl-3-Pentanone’s secret sauce sits in its balance between volatility, odor, and chemical resistance. We’ve seen this compound carve out a niche where that combination really counts—making it one of our most reliable performers over the long haul.

    End Uses Shaped by Field Knowledge

    Clients in the flavor and fragrance sector keep coming back for 2-Methyl-3-Pentanone because of its faint, sweet, and non-persistent odor. Our experience shows it doesn’t overpower subtle aromatic blends, so perfumers and formulators rely on its contribution as much as on its solvency. In agrochemical synthesis, especially when working on intermediates like substituted pyridines or phenols, we hear appreciation for its inertness under mild acid or base treatment. We tracked reduced byproduct formation when switching from MIBK to 2-Methyl-3-Pentanone in certain Grignard reactions—a small point, maybe, but a big deal for those chasing a reliable product profile.

    Sourcing managers in the coatings industry report smoother film formation when using 2-Methyl-3-Pentanone versus lower-molecular ketones. Its evaporation rate supports even drying especially for high-gloss and specialty finishes. In adhesives and inks, you find better control of viscosity, and less yellowing on storage. These insights didn’t come from simply reading literature—they came from years of field trials, troubleshooting, and feedback that fed right back into our process improvement meetings.

    Handling and Storage: Learning from the Lab and the Line

    After decades splitting time between the bench and the production floor, I’ve found that storage conditions shape quality more than any fancy stabilizer. 2-Methyl-3-Pentanone needs dry drums and tight seals. We use nitrogen blanketing for large lots, and we keep our warehouse below 30°C—every season, we run retention samples side by side to catch shifting quality. Large tanks need lined walls. Any trace of water makes for cloudiness on standing, and older, rusty drums can kick off peroxides much faster than new poly liners. We switched to phenolic-lined caps for the small packs to control trace corrosion and keep the product stable through months of storage.

    In my view, no technology replaces plain vigilance. Each drum gets a retest if it sits more than half a year. After hearing from one high-volume paint maker about gradual color drift, we began including monthly stability checks alongside regular QA. These inside tips, learned from solving real-world complaints, built the reliability that return customers notice.

    Upstream Raw Materials and Traceability Standards

    From a manufacturer’s lens, quality tracks back to raw materials. For 2-Methyl-3-Pentanone, we watch for variations in isoamyl alcohol supply. Cheap alcohols introduce side impurities. Over the years, we built relationships with two certified sources and spot check each new shipment for aldehyde content and sulfur residues. If you think a ketone’s a ketone, wait until you see a yellow cast from trace sulfur slipping through and spoiling a full truck of intermediate. Marking drums with batch and raw material lot information adds cost, but every ruined batch avoided pays for itself.

    Every month, we compare our own in-house distillation purity against third-party labs. Customers welcome data transparency, and we share chromatograms showing impurity spikes if they occur. We neither hide nor sugarcoat results when the real world produces a surprise—chemistry rewards accountability over marketing puffery.

    Packing, Cost, and Supply Chain—Practical Decisions, Not Just Paperwork

    Most 2-Methyl-3-Pentanone leaves our facility in steel drums or HDPE containers, depending on customer workflow. Bulk buyers, such as those blending for the coatings industry, use our returnable tanks, built to stand up to repeated fill and transfer cycles without picking up metallic flavors or dust. Smaller drum customers, typically lab supply houses or custom synthesis shops, tend to need clean headspace and tighter seals. We vacuum-pack smaller bottles for analytical use following a string of complaints about headspace exchange during long-haul shipping.

    Every shipment gets tracked not just for loss, but for thermal exposure. Each summer, we check temperature loggers after a few loads traveled overland in hot weather and apply cold packs if the delivery route includes extended transits through high-temperature zones. This simple intervention came straight from customer conversations and internal QA correlations—not from a packaging guideline.

    Regulatory and Safety Realities—What Experience Teaches

    2-Methyl-3-Pentanone raises the same safety points as most mid-weight organic solvents: moderate flammability, potential for mild irritation, and need for good ventilation. Still, our clients appreciate honest advice on secondary containment, eye protection, and compatible materials. We warn about long-term storage near peroxides and suggest using static-free containers, especially for operations in dry or dust-prone environments. Our health and safety team conducts periodic refresher walkthroughs with frequent users, sharing what we’ve learned about preventing minor leaks and prompt spill response.

    Working with hundreds of customers turns up regulatory quirks in different regions. We update our technical bulletins the moment new restrictions on VOC emissions or handling pop up, since waiting to hear from a regulator after a delay never ends well. Compliance is never an afterthought for us—it helps us build trust, saves headaches, and, most importantly, keeps workers safe.

    Sharing Insights and Solutions—What Sets Our Approach Apart

    Real lessons come not from theory, but practice. We’ve seen competitors cut corners with storage or push out products without the needed stability testing, only to find themselves fielding quality complaints. Our approach to 2-Methyl-3-Pentanone is born of day-to-day engagement: if we see a new off-odor, we dig back to the source; if a paint batch clouds up, we troubleshoot and replace. Our technical service team doubles as our in-house R&D arm, bridging what we learn at the reactor with what our customers demand at the endpoint.

    From customer labs chasing a sharper solvent cut to production floors looking for a cleaner, drier product, we build real-time feedback into every campaign. That experience helps us make the product better, batch after batch. Over years, the tweaks add up—more robust containers, tighter purity specs, and faster response when field challenges pop up. We don’t just ship drums and invoices—we look for the feedback that shapes the next run, and we listen when something isn’t working.

    The Importance of Direct Dialogue

    We’ve always believed that two-way conversation beats vague promises. Many customers reach out directly to discuss formulation, scale adjustments, or new application areas. We bring that feedback back to our bench, measure new variables, and run small trials to see how tweaks in distillation or packing perform in practice. This loop of real-world feedback drives incremental improvements, like revisiting filtration steps to cut out suspended solids after a run of customer reports.

    End users appreciate manufacturers who listen and act, not just talk about transparency or quality. Solutions grow from experience, patience, and honest reporting. We see product quality as a matter of trust, shaped by steady work instead of shortcuts.

    Looking Ahead with 2-Methyl-3-Pentanone

    Markets shift, regulations tighten, and customer applications evolve. What won’t change is our way of working. We keep our processes nimble to respond to new purity or packaging needs. As new sectors turn to 2-Methyl-3-Pentanone for unique solvent or synthetic roles—think high-purity pharmaceuticals or advanced functional coatings—we adjust upstream supply, distillation, and QA to keep up. Being close to the process, from raw materials to the finished drum, means we can catch issues before they grow and offer practical solutions, not theoretical fixes.

    The real value of working directly with a manufacturer comes from this depth of experience. Each campaign, each process tweak, and every call from a customer shapes the hard-won knowledge that makes every batch of 2-Methyl-3-Pentanone a little more reliable, a little more predictable, and a lot more useful for the people trusting it in their production every day.

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