Products

2-Methyl-1-Propanol

    • Product Name: 2-Methyl-1-Propanol
    • Alias: Isobutanol
    • Einecs: 200-746-9
    • Mininmum Order: 1 g
    • Factroy Site: Yudu County, Ganzhou, Jiangxi, China
    • Price Inquiry: admin@ascent-chem.com
    • Manufacturer: Ascent Petrochem Holdings Co., Limited
    • CONTACT NOW
    Specifications

    HS Code

    990270

    Cas Number 78-83-1
    Iupac Name 2-Methylpropan-1-ol
    Common Name Isobutanol
    Molecular Formula C4H10O
    Molar Mass 74.12 g/mol
    Appearance Colorless liquid
    Density 0.802 g/cm³
    Melting Point -108 °C
    Boiling Point 108 °C
    Solubility In Water 85 g/L (at 20 °C)
    Odor Sweet, musty odor
    Flash Point 28 °C (closed cup)
    Vapor Pressure 10 mmHg (20 °C)
    Refractive Index 1.395 (20 °C)
    Logp 0.79

    As an accredited 2-Methyl-1-Propanol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing The packaging is a 500 mL amber glass bottle with a secure screw cap, labeled "2-Methyl-1-Propanol" and hazard symbols.
    Shipping 2-Methyl-1-Propanol (also known as isobutanol) is shipped as a flammable liquid. It should be transported in tightly sealed containers, clearly labeled, and kept away from heat, sparks, open flames, and oxidizing agents. Compliance with relevant regulations (such as DOT, IATA, or IMDG) for hazardous materials is required during shipping.
    Storage 2-Methyl-1-propanol should be stored in a cool, dry, well-ventilated area away from heat, sparks, and open flames. Keep the container tightly closed and properly labeled. Store away from strong oxidizing agents and acids. Use only approved containers compatible with alcohols. Prevent moisture ingress and avoid direct sunlight to reduce decomposition and fire risk. Ground containers when dispensing to prevent static buildup.
    Application of 2-Methyl-1-Propanol

    Applications of 2-Methyl-1-Propanol in Industrial Manufacturing

    2-Methyl-1-Propanol serves as a critical intermediate, solvent, and additive across several specialized industrial sectors. Our manufacturing expertise ensures consistent batch quality tailored to tightly regulated downstream applications. Below we outline the primary sectors utilizing our product, including practical details on regulatory compliance, process integration, and finished goods.

    1. Industrial Coatings and Paints Manufacturing

    Paint and coating producers select 2-Methyl-1-Propanol for its effective performance as a co-solvent, especially in water-reducible and high-solids formulations. It enables efficient resin dissolution, improves flow and film formation, and assists with open-time control. Manufacturers must follow stringent limits on residuals and VOCs for workplace safety and final product environmental release.

    Industry compliance standards

    • EU REACH Regulation (EC) No 1907/2006
    • US EPA Clean Air Act VOC limits (40 CFR Part 59)
    • China GB 18582—2020: Indoor wall coating materials standards
    • ISO 9001:2015 quality management for coatings production

    Typical usage ratio

    • 2–8% by total coating solids, adjusted based on resin type and targeted VOC content

    Downstream process integration

    • Added post-emulsification in aqueous systems to improve solvent balance
    • Introduced at pigment dispersion or letdown stage for alkyd acrylics
    • Used during viscosity adjustment after polymer synthesis

    Final product types

    • Architectural paints for interior and exterior use
    • Industrial machinery and equipment coatings
    • Protective anti-corrosive primers
    • Automotive refinishing paints

    2. Printing Ink Formulation

    Manufacturers in the printing ink sector add 2-Methyl-1-Propanol as a solvent and evaporation controller, particularly for flexographic and gravure inks. It enhances pigment wetting and stabilizes viscosity, while its moderate volatility enables rapid setting and reduced print defects. Downstream formulation must respect occupational safety and national food packaging migration limits where applicable.

    Industry compliance standards

    • Swiss Printing Ink Ordinance (SR 817.023.21), for food contact inks
    • EU Regulation 2023/2006 on GMP for food contact materials
    • ISO 2846-1: Color and transparency standards for ink
    • OSHA 1910.1200 worker exposure controls

    Typical usage ratio

    • 1–6% of total liquid phase, modified according to ink drying speed and substrate type

    Downstream process integration

    • Blended with alcohols and esters prior to pigment dispersion
    • Added during vehicle preparation for viscosity control
    • Included in final adjustment before ink filling and packaging

    Final product types

    • Flexographic inks for flexible packaging films
    • Gravure inks for magazines and consumer goods packaging
    • Specialty inks for labels and shrink sleeves
    • Inks for tissue and napkin printing

    3. Pharmaceutical Intermediate Synthesis

    The pharmaceutical industry applies 2-Methyl-1-Propanol primarily as an intermediate in active pharmaceutical ingredient (API) syntheses and as a process solvent. Chemists rely on its branching structure during Grignard and substitution reactions. Production mandates precise residual solvent control and full compliance with global pharmacopoeia purity standards and traceability throughout the supply chain.

    Industry compliance standards

    • USP/NF (United States Pharmacopeia-National Formulary)
    • European Pharmacopoeia (Ph. Eur.)
    • ICH Q3C: Guidelines for residual solvent limits
    • GMP (ICH Q7) for API manufacturing

    Typical usage ratio

    • 5–20% as solvent or reagent, based on specific API synthetic requirements; levels optimized for solubility and separation efficiency

    Downstream process integration

    • Charged at reaction start in alkylation or addition synthesis
    • Used for crystallization or extraction stages in API isolation
    • Removed by distillation and monitored during final purification

    Final product types

    • Intermediates for antihistamines and CNS drug synthesis
    • API batches for finished pharmaceutical formulations (tablets, capsules)
    • Fine chemical intermediates for contract manufacturing
    • Reference substances for analytical laboratories

    4. Fragrance and Flavor Ingredient Processing

    Leading fragrance and flavor manufacturers utilize 2-Methyl-1-Propanol as a specialty solvent and reaction intermediate in the production of esters and aldehydes. It enables selective transesterification and imparts specific olfactory notes in finished compounds. Producers must comply with food-grade purity, allergen control systems, and international food additive safety lists for both ingredient and processing aid roles.

    Industry compliance standards

    • IFRA (International Fragrance Association) Standards
    • US Food Chemicals Codex (FCC) for food-use ingredients
    • EU Regulation (EC) No 1334/2008 – Flavorings regulation
    • ISO 22000:2018 for food safety management

    Typical usage ratio

    • 0.5–3% as a solvent or processing aid, increased in encapsulation or ester synthesis as required by targeted aroma

    Downstream process integration

    • Reacted with acid chlorides or acids for ester synthesis
    • Used as a process solvent in fractionation of aroma chemicals
    • Applied during final dilution for concentrate production

    Final product types

    • Fine fragrances (eau de toilette, perfume bases)
    • Flavor concentrates for bakery and confectionery
    • Functional food and beverage aroma additives
    • Personal care scented products

    5. Plasticizer Manufacturing for Flexible Polymers

    Chemical manufacturers employ 2-Methyl-1-Propanol in plasticizer synthesis, where it participates in esterification with phthalic or adipic acid derivatives. Its presence adjusts the volatility and flexibility profile of the resultant plasticizer, used in compliance-heavy applications such as food packaging films and medical tubing. Quality assurance focuses on migration limits, mechanical performance, and low odor transfer.

    Industry compliance standards

    • EU Regulation (EC) No 10/2011 for plastic food contact materials
    • US FDA 21 CFR 177.2600 (elastomers) and 178.3740 (plasticizers)
    • ISO 9001 manufacturing traceability requirements
    • EN 1186: Migration testing for food contact plastics

    Typical usage ratio

    • 10–25% in reaction blend during esterification, ratio controlled to balance flexibility and migration resistance

    Downstream process integration

    • Combined with dibasic acids and catalyzed under reflux
    • Purified post-reaction via distillation
    • Blended into polymer compounding lines for flexible products

    Final product types

    • Flexible PVC food wrap films
    • Medical-grade tubing and bags
    • Plasticized adhesives and elastomeric coatings
    • Children’s toys and molded consumer items

    6. Extraction and Separation in Analytical Chemistry

    2-Methyl-1-Propanol acts as a selective organic phase in sample preparation and extraction protocols for industrial analytical laboratories. It enables separation of polar and non-polar analytes for environmental, food, and pharmaceutical testing. Use must reflect validated method requirements and international laboratory accreditation standards.

    Industry compliance standards

    • ISO/IEC 17025:2017 for laboratory competence
    • EPA SW-846 Test Methods for Evaluating Solid Waste
    • AOAC Official Methods of Analysis
    • USP General Chapter <467> on residual solvents testing

    Typical usage ratio

    • 1–10% of extraction solvent mixture; precise ratio adjusted according to sample matrix and analyte polarity

    Downstream process integration

    • Mixed with water or other alcohols in liquid-liquid extraction
    • Applied in preparation of calibration standards
    • Utilized in automated sample handling systems

    Final product types

    • Certified analytical reference samples
    • Environmental sample extracts
    • Food contaminant analysis reports
    • Pharmaceutical impurity and residual solvent data packages

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    Certification & Compliance
    More Introduction

    2-Methyl-1-Propanol: Experience Earned on the Factory Floor

    Understanding 2-Methyl-1-Propanol Beyond the Textbook

    Working in chemical manufacturing means gaining an appreciation for the unique personality each product brings to the operation. 2-Methyl-1-Propanol, or isobutanol as many call it, stands out in its own right. In the hands of our seasoned teams, it transitions from a simple clear liquid to a reliable backbone in countless applications, thanks to its manageable reactivity and straightforward purification. We’ve watched its performance over years of batch testing and product integration, learning which characteristics make a difference for our customers and what sets it apart from similar alcohols.

    Technical Clarity: How We Prepare Our 2-Methyl-1-Propanol

    Producing 2-Methyl-1-Propanol at scale means balancing purity and consistency with practical considerations like yield, packaging, and logistics. Our standard approach involves rigorous quality controls, ensuring water and other volatile impurities stay well beneath accepted thresholds. Each batch exits the distillation columns with a clear, colorless appearance, a mild, distinct odor, and a low water content, in line with the expectations of demanding industries. The most widely used packaging remains steel drums and IBCs, chosen for their compatibility and ease of storage. Bulk road tankers serve larger volume clients who require steady, uninterrupted supply runs to their plants. We do not rely on third-party blending, ensuring direct accountability from reactor to warehouse.

    The Chemistry in Action: Real Industry Uses and Lessons Learned

    Chemistry is a world full of nuances, especially for families of solvents. Isobutanol features a high flash point among lower alcohols, holding its own in terms of safety during storage and handling compared to its lower-weight cousins. Clients in coatings and inks share their results with us: they value the moderate evaporation rate, which prevents their paints from drying too fast or leaving brush marks during application. Resins and plasticizers rely on 2-Methyl-1-Propanol for its solvency power and compatibility with urea-formaldehyde and melamine resins, which can be hard to process smoothly without a tailored solvent. We see downstream users blending isobutanol into antifreeze products, where it disrupts ice crystal formation without thickening the mixture, and in the pharmaceutical sector, it works as a trusty reaction medium for synthesis requiring a stable, mid-polarity solvent.

    Each application reinforces the simple fact: a solvent’s real-world value comes from the everyday challenges it solves, not just its chemical formula. Teams from adhesives, coatings, and agricultural chemical makers tell us about improvements in batch reproducibility and ease of blending, which saves both time and raw materials.

    Not All Alcohols Are Created Equal: The Differences in Practice

    Across the solvent category, the differences between isobutanol and other four-carbon alcohols matter in day-to-day production. Regular n-butanol, for instance, offers a higher boiling point but can be slower to dry and linger more in end-use products. Isobutanol brings a lower boiling point (just over 100°C) and a distinct, less pungent odor profile, making it easier on operators handling open vessels. By contrast, methanol and ethanol, the lighter, more volatile types, dry too fast for certain uses and carry much greater regulatory scrutiny, especially due to toxicity concerns.

    The balance of evaporation speed and solvency often drives the decision. We’ve heard from printing ink formulators that n-butanol makes their presses run sticky under humid conditions; swapping to 2-Methyl-1-Propanol resolves the issue by improving flow and reducing excess wetting, with little need for formula rework. In our plastics customers’ notebooks, isobutanol scores higher for safety due to its lower skin absorption and vapor toxicity than lighter alcohols. Anecdotes from our drums at shipping docks confirm what technical data can only hint at: isobutanol’s performance, especially in processes with tight time windows, delivers remarkable reliability.

    A Manufacturer’s View: Quality, Safety, and Compliance

    Daily operations drill into us the importance of documentation and traceability. We operate under strict process supervision—every shift, every sample, every emergency drill. Tracking each lot involves more than checking a box: it’s a routine built from decades of lessons learned. Isobutanol’s flammability and vapor pressure get a lot of industry attention, particularly in warm climates or packed warehouses. Our facility’s real-world experience led to installing continuous vapor detectors near bottling lines, which alerts the team if concentrations rise. Together we conduct regular fire safety and spill response drills using our own finished product, so there is no surprise during real incidents.

    Isobutanol’s regulatory climate continues to shift. International shipping laws and domestic transport rules place limits on route options, storage volumes, and packaging types, different from lighter alcohols under comparable regulations. Our compliance team dedicates hours to tracking, not only chemical bans but evolving workplace exposure limits. Safety data is not a one-time exercise. Close communication with authorities and customers means we spot issues ahead of legal deadlines. These steps are not empty rituals—they help keep operations moving without interruption.

    Challenges and Adaptations Over the Years

    Every process run brings a fresh set of challenges. Batch inconsistencies sometimes show up as minor color hazes or faint odorous traces. Our production team doesn’t wait for complaints before investigating—routine sampling and off-line testing under varying storage and distribution conditions drive many of our workflow improvements. For instance, we fine-tuned our drying tower temperature profile several years ago after repeated feedback about drum residues in hot climates. By focusing on evidence from real shipments, we saw the difference in end-use quality quickly.

    Solvent price volatility has also forced careful planning. Isobutanol follows the propylene market; supply squeeze or refinery disruption quickly translates to cost spikes. Rather than cut corners, we doubled down on plant-wide energy efficiency upgrades and supply chain transparency. These investments have smoothed out scheduling, even during raw material scarcity, and protected long-term relationships with key customers who rely on predictable shipments.

    Scientific Roots, Practical Reality: The Making of 2-Methyl-1-Propanol

    Producing 2-Methyl-1-Propanol demands respect for chemistry and machinery alike. Dehydration of fermentation-derived feedstocks, followed by fine-tuned catalysis, sets the foundation. Even small shifts in feedstock purity or reaction temperature throw off selectivity, leading to undesirable by-products. The separation stage uses fractional distillation, where precise control over column reflux ratios cuts down on contamination risk. Maintenance technicians learn quickly that even a small leak in the distillation head leads to losses and operational headaches.

    Process engineers rarely work in isolation. Operator feedback shapes how raw material flows are calibrated; mechanics monitor heat exchanger fouling; analysts check the output for both expected yield and trace contaminants. The human element—skilled hands operating control panels, alert eyes walking platforms—makes the difference between textbook yield and commercial, repeatable production. Our culture of open communication and error prevention helps minimize downtime and avoid emergency shutdowns, which can waste entire day’s work and thousands of liters of product.

    Long-Term Relationships: Working With Customers Beyond a Sale

    Strong customer relationships do not grow out of sales scripts or promotional offers, but from technical support and clear answers when problems arise. Specialty coatings producers request insight into shelf-life performance under challenging warehouse climates. We work closely with their technical staff, sometimes joining on-site tests, to see how our product integrates into their unique processes. Ink manufacturers send us samples of dried films for feedback on gloss and adhesion; our technical team reviews returns for off-odors or color drift, helping adjust future batches as required. Sometimes customers ask us to analyze fouling in their pipes or residue in mixers, sending us photographs and samples that inform our own R&D.

    A reliable supplier-customer bond often depends on more than product quality. Transparent communication about planned shutdowns or unplanned outages—such as during force majeure events—can determine whether our clients can keep their lines running. We keep a running log of customer questions and feedback, taking the time to share what works and what hasn't. No two factories run the same way; our long-standing experience has shown that sometimes, changing delivery timing or packaging method solves more issues than tweaking product specifications.

    Storing and Handling With the End User in Mind

    Isobutanol storage is more than a matter of fire codes and drum labels. Field visits to customer sites have taught us that heat and humidity swing drum pressure, sometimes leading to minor venting or spillage. Revising batch sizes for certain users, offering smaller lots or split shipments when warehouse space tightens, makes a real difference in keeping overall operations safe and efficient. Guidance on decanting, drum rotation, and residue minimization flows directly from production team experience to customer SOPs. Our technical guides come from practical experience, not just compliance checklists.

    Transitioning to bulk delivery, some larger clients invested in stainless steel tank farms for long-term storage. Their teams raised questions about vapor losses, cross-contamination, and purification for process-critical uses. Joint troubleshooting on-site led both sides to adopt new vent condenser setups and lined transfer hoses, preventing evaporation loss and costly rework. Our company’s skills and resources become a shared asset for clients, not just a selling point.

    Innovation Grounded in Operations, Not Hype

    Much gets made of trendy process upgrades or sustainability projects in chemical production. For us, practical efficiency always wins. Switching to higher-recovery distillation trays and improved catalytic membranes took patient trial, but paid off in reduced waste and incrementally better purity—outcomes measurable by each drum’s QC data. A project in reusing recovered process steam led to consistent heat energy savings, shrinking both emissions and operating costs, and making cost stability easier to deliver downstream.

    Client priorities also change. Several years ago, a key customer from the electronics sector asked for ultra-low water content isobutanol for high-purity applications. We reconfigured part of the purification loop, adding molecular sieve beds and online water analytics, to hit these tougher specs. The work was not glamorous, but the end result brought new demand from a wider segment, fueling future investment and building new expertise in our crew.

    Continuous Learning: Training the Next Generation

    A company’s longevity in chemical manufacturing rests on real skill transfer, not just equipment upgrades. Older operators routinely pair with new hires, sharing hands-on know-how about handling isobutanol spills, dealing with process upsets, or diagnosing incomplete reactions. We invest in training sessions covering safe transfer, exposure prevention, and emergency troubleshooting. Lessons learned from near-misses—logs full of small incidents and fixes—are taught as much as textbook chemistry. The manufacturing plant becomes a living classroom; best practices are recorded, and worst-case errors are both dissected and addressed head-on.

    Investment in skills, from process chemistry to logistics coordination, keeps problem-solving abilities sharp. Regulatory standards shift, new end-use industries emerge, and client questions grow more sophisticated. Adaptation comes from ongoing education, not just rule following. This philosophy, shaped over decades, keeps our company and our industry moving forward.

    Looking Ahead: The Future of 2-Methyl-1-Propanol in Manufacturing

    Market demand never stands still. Today, pull comes not just from traditional coatings or antifreeze, but also bio-fuels, specialty polymers, and new lightweight composite materials. Our technical teams keep their ears to the ground for changes in environmental regulations, new process technologies, or customer requirements. Experience tells us that reliability and flexibility matter most—being able to maintain steady supply, troubleshoot for unique process headaches, and deliver consistent quality. As industries raise the bar on emissions and workplace safety, manufacturing and tracking high-quality solvents only gets more important.

    Operational wisdom, built through handling, testing, and adapting each batch, keeps quality and reliability at the center. We draw on long-term industry insight, not just today’s headlines, to support customers as the chemistry landscape evolves. Every drum and tanker load we ship carries the weight of our team’s experience, pride, and willingness to learn. 2-Methyl-1-Propanol, in all its roles, remains more than just a chemical—it’s a product shaped by years of real production and grounded trust.

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