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HS Code |
316608 |
| Cas Number | 88-73-3 |
| Molecular Formula | C6H4ClNO2 |
| Molar Mass | 157.56 g/mol |
| Appearance | Pale yellow crystalline solid |
| Melting Point | 53-54 °C |
| Boiling Point | 242 °C |
| Density | 1.36 g/cm³ |
| Solubility In Water | Insoluble |
| Flash Point | 113 °C |
| Odor | Aromatic |
| Pubchem Cid | 7127 |
As an accredited 2-Chloronitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 2-Chloronitrobenzene is packaged in a 500g amber glass bottle, sealed with a screw cap and labeled with hazard warnings. |
| Shipping | 2-Chloronitrobenzene is shipped as a hazardous chemical. It should be packed in tightly sealed containers, clearly labeled, and transported according to regulations for toxic and environmentally hazardous substances. Appropriate protective measures against spills, fire, and exposure are required during shipping. Consult local, national, and international guidelines for specific handling and documentation. |
| Storage | 2-Chloronitrobenzene should be stored in a cool, dry, well-ventilated area away from heat, ignition sources, and direct sunlight. Keep the container tightly closed and labeled. Store separately from incompatible materials such as strong acids, bases, and reducing agents. Use chemical-resistant shelving and secondary containment to prevent spills. Follow all relevant safety and regulatory guidelines for storage. |
Applications of 2-Chloronitrobenzene in Industrial Manufacturing2-Chloronitrobenzene serves as a critical intermediate in various chemical manufacturing industries. Its role spans downstream in dyed chemistry, pharmaceutical synthesis, agricultural compounds, and specialty polymers, where strict quality and compliance standards govern its usage and integration. Below, we detail the primary industrial application scenarios, compliance expectations, application processes, typical concentrations, and finished goods that rely on this raw material. 1. Synthesis of Dye Intermediates for Azo and Anthraquinone DyesLarge-scale dye manufacturers use 2-chloronitrobenzene as a starting material to produce key intermediates like 2-chloroaniline or 4-nitro-2-chloroaniline. This process involves nitration and subsequent reduction, requiring controlled reaction parameters to ensure high purity. End uses include commercial textile dyes and inks meeting stringent color fastness requirements. Each batch undergoes analysis for impurity profiles according to international textile chemical standards. Waste management during reduction—especially dealing with by-product anilines—requires documented compliance with chemical emissions regulations. Industry compliance standards
Typical usage ratio
Downstream process integration
Final product types
2. Agrochemical Manufacturing for Soil Fumigants and Herbicide IntermediatesAgrochemical producers deploy 2-chloronitrobenzene in synthesis chains for herbicide and soil fumigant precursors. It enters key condensation reactions to yield compounds like o-chloroaniline, later transformed into triazine and anilide herbicides. Careful handling under contained systems is mandated to prevent operator exposure. Traceability reports for each batch document compliance with global pesticide ingredient guidelines. Residual content checks at plant gate follow agrochemical regulation on maximum allowable impurity levels. Industry compliance standards
Typical usage ratio
Downstream process integration
Final product types
3. Pharmaceutical API Intermediate for Antimicrobial AgentsAPI producers integrate 2-chloronitrobenzene in the multi-step synthesis of certain antimicrobial molecules. During the route toward drugs such as chloramphenicol or nitroaromatic antibacterials, the raw material’s purity directly affects downstream GMP validation and impurity control. Quality parameters such as residual solvents, heavy metals, and isomers are tightly monitored, as minute fluctuations lead to out-of-specification batches. Pharmaceutical-grade handling takes place in controlled environments with comprehensive analytical documentation per cGMP and pharmacopeial standards. Industry compliance standards
Typical usage ratio
Downstream process integration
Final product types
4. Production of Rubber Chemicals and Vulcanization AcceleratorsThe synthetic rubber industry incorporates 2-chloronitrobenzene for the production of accelerators including CMB (N-cyclohexyl-2-benzothiazole sulfenamide) and others. Manufacturers introduce this compound in controlled reactors to produce intermediates that influence vulcanization speed, cure profile, and physical properties of rubbers. Process integration focuses on precise dosing and impurity filtration to meet tire and technical rubber performance criteria. Downstream users demand documentation for batch traceability and conformance with auto industry QA protocols. Industry compliance standards
Typical usage ratio
Downstream process integration
Final product types
5. Specialty Polymer Synthesis for Engineering PlasticsPolymers producers invoke 2-chloronitrobenzene as a monomer modifier in the creation of high-performance engineering plastics, providing halogenated aromatic units for polymer chains. Application includes polymerizing with other substituted aromatics to tailor glass transition temperature, flame resistance, and mechanical strength. Raw material consistency impacts batch reproducibility, especially important in electronics or appliance housings. Analytical QC tracks residual monomers to prevent undesired yellowing in finished polymer goods. Industry compliance standards
Typical usage ratio
Downstream process integration
Final product types
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In our production lines, 2-Chloronitrobenzene stands out for both its reactivity and functional group positioning, shaped for use in mid- to large-scale chemical synthesis. For over fifteen years, our plant teams have worked with this compound, refining every stage from chlorination of nitroaromatics to the purification process which ultimately brings our customers a product with reliable purity and yield. Taking end-user feedback from downstream processors, agricultural intermediates handlers, and dyestuff formulators, we continually return to our batch analytics to ensure every run meets the level demanded by practical chemical manufacturing.
This compound carries a chlorine atom and a nitro group each attached to a benzene ring at the ortho position. Such a configuration gives it a reactive edge for further chemical transformations used in industrial applications. We consistently hit assay ranges upwards of 99% purity using proprietary methods developed by our in-house R&D teams, matching the evolving benchmarks in the agrochemical and pharmaceutical industries.
Plants like ours pay attention to what makes 2-Chloronitrobenzene work for people scaling up processes. Minute traces of impurities throw off subsequent hydrogenations or aminations, so we optimize temperature, pH, and solvent types for better separation. Years back, inconsistent batches would cause downstream polymer yellowing during dye manufacture, wasting both materials and time. After collaborating with partners at dye facilities, our team developed a multi-step crystallization to cut colored byproducts. This allowed our long-term clients to tighten color consistency in everything from synthetic fibers to treated leather goods, which tells us our investment translates right into end-user profits.
Our 2-Chloronitrobenzene leaves the gate as pale yellow crystalline flakes, melting around 53°C, a touchpoint which chemists trust for incoming quality checks. Standard moisture readings stay below 0.3% (Karl Fischer determination), and we work to compress the isomer profile so no more than a fraction of a percent of para- or meta- forms float through. Maintaining low combined halogen residues matters to our European partners facing tighter REACH standards—these are practical considerations feeding directly into the way we operate, not just arbitrary numbers on a document.
Day-to-day, we watch 2-Chloronitrobenzene roll out on trucks bound for companies making 2-chloroaniline or 2-aminophenol. The transformation of this nitroaromatic starts with our quality, as every impurity shows itself in hydrogenation reactors or amination kettles downstream. Years ago, inadequately purified lots led to filtration headaches at a partner plant. By working closely with their technical group, we stripped down our distillation profile; this gave them better throughput and cut their filtration downtime significantly.
Pesticide and herbicide manufacturers rely on us for consistent supply, as many phenoxyacetic acid herbicides call for a reliably pure ortho-chloronitro feedstock. In dye manufacturing, the importance is twofold: achieving vibrant shades in azo dye intermediates and avoiding streaking or fading in finished textiles. The leather and pigment sectors require the most stable, lightfast grades, for which our custom-flaked materials meet approval as we adjust process cooling rates to control particle morphology—something that took us years to nail down.
As a chemical facility handling chlorinated aromatics, we learned quickly that odor and vent management is not optional. Our team runs activated carbon beds and regenerative incineration units which treat process exhaust before current ever leaves the stack. Over the last decade, routine leak detection surveys, along with automated process controls, have helped us cut plant fugitive emissions by over 30%, and these proactive controls now give us both community trust and regulatory compliance. Waste streams undergo batch neutralization to drop chlorinated contaminants before any water enters the municipal system. We've seen cheaper, less diligent handling from some competitors, which may get product out the door, but never sustains reputation in the markets we serve.
Handling 2-Chloronitrobenzene means respecting its moderate toxicity and persistence—gloves, goggles, and closed charging systems became standard in all plant zones after several near-miss incidents. Our team commissioned a full process hazard analysis each quarter, not just for compliance, but after seeing how unreported leaks and surface contamination can accumulate over shift cycles. Reducing open transfer minimised chronic exposure to nitro vapors, keeping both operator health and product quality front of mind. These investments in safer charging and digital batch monitoring mean fewer off-spec runs and a healthier plant workforce.
Disruptions over the years—including sudden demand hikes or port closures—taught us the value of local raw material sourcing and redundant utility systems. Where other suppliers struggled or rationed product, our facility kept operations running by launching backup solvent storage and alternative rail loading stations. As a result, customers counting on time-sensitive intermediates rarely see delays, even as global shipping remains unpredictable. This commitment brings steady, on-spec shipments, which matters most when chain reactions downstream depend on each ton we deliver.
Chemists often ask what separates 2-Chloronitrobenzene from its meta- and para- isomers or from nitrobenzene itself. We see the impact right in our tanks: the ortho position of chlorine to nitro in the benzene ring changes reactivity dramatically. Ortho compounds serve as better substrates for ortho-directed nucleophilic substitution, especially when synthesizing certain pharmaceuticals and specialty dyes. Meanwhile, para- derivatives behave differently under reduction or coupling, leading to changes in the quality of down-the-line colorants and herbicides. Our focus remains on the ortho isomer, not just for higher value, but because our methods allow finer isomeric separation and fewer side product headaches for downstream chemists.
Compared to nitrobenzene, which lacks a halogen and serves mainly as a precursor to aniline, 2-Chloronitrobenzene offers more targeted synthetic possibilities. Our R&D team sees particular customer requests for ortho-chloro functionality when building custom active ingredients or advanced materials. Cutting cross-contamination with nitrobenzene or meta-chloronitro forms is more than just good practice—it prevents wasted reaction cycles for compounders attempting complex, multi-step transformation.
Our experience doesn’t stop at routine batch manufacture. Sometimes a client needs help with solubility during solvent switches, or encounters precipitation in their jacketed reactors. We step in with practical technical guidance, sometimes sending a chemist onsite or arranging remote troubleshooting. Case in point: one of our agricultural customers faced precipitation during formulation due to a winter temperature dip. By providing a tailored flake-size distribution and delivering on a heated trailer, we helped keep their process smooth through the coldest months.
True partnerships come from covering challenges like handling, inventory management, and storage advice. Our packaging coordinators work directly with users to meet needs for lined drums, bulk containers, and protective barriers which guard against seasonal moisture cycles. This keeps the product free-flowing and usable with minimal downtime.
Current market trends push for enhanced traceability and lower impurity limits. EU regulatory changes demand painstaking documentation for every kilogram. Years of targeted investment in process analytical technologies (PAT) and digitized quality management now show their value as customers audit our production lines or request full batch histories. We meet the demand for compliance-ready material without creating bottlenecks or losing production flexibility.
As demand for specialty chemicals grows—especially in crop protection and high-performance coatings—consistency across thousands of tons remains crucial. Spot buying and speculative traders often try to fill sudden gaps, yet downstream processors quickly notice lot-to-lot variability or unexplained side reactions. Through steady, direct manufacturing, we supply peace of mind along with bulk tanks, giving formulators and syntheses teams the confidence to scale their own innovations.
Sustainability pressures touch every manufacturer working in chlorinated aromatics. We see the push for lower carbon footprints and circular processes arriving with both regulatory force and genuine customer concern. Internally, we continue R&D into solvent recovery, greener oxidants, and alternative waste treatments. Already, heat exchangers on our reactors reclaim process energy, and waste solvent routing lowers total hazardous output. As environmental benchmarks keep shifting upward, our drive remains rooted in practical change: not just on paper, but in visible daily operations that improve the plant and the neighborhood.
Supply chain risk increased after global events in recent years. Our experience tells us steady, in-house production with robust safety and QA gives customers the lowest risk. We're open to collaboration, joint development, and custom specifications—as that’s been the backbone of a business standing for decades, not passing trends. Process insights, troubleshooting support, and reliable delivery: these values guide every ton we make and every partnership we form.
Handling and supplying 2-Chloronitrobenzene means understanding not just chemistry but the real-world processes our products enter. Plants that rely on us expect honesty, adaptability, and consistent results. Decades’ worth of lessons—from raw material storage adjustments to process line upgrades—feed into each kilogram that leaves our site. We remain committed to continuous improvement, transparent practices, and shared technical knowledge, so that our product does more than fill a spec sheet: it forms the foundation for reliable, innovative, and responsible industrial chemistry worldwide.
