Products

2-Chlorofluorobenzene

    • Product Name: 2-Chlorofluorobenzene
    • Alias: o-Chlorofluorobenzene
    • Einecs: 209-002-3
    • Mininmum Order: 1 g
    • Factroy Site: Yudu County, Ganzhou, Jiangxi, China
    • Price Inquiry: admin@ascent-chem.com
    • Manufacturer: Ascent Petrochem Holdings Co., Limited
    • CONTACT NOW
    Specifications

    HS Code

    999434

    Chemicalname 2-Chlorofluorobenzene
    Casnumber 367-11-3
    Molecularformula C6H4ClF
    Molecularweight 130.55 g/mol
    Appearance Colorless liquid
    Boilingpoint 128-130°C
    Meltingpoint -32°C
    Density 1.26 g/cm³
    Refractiveindex 1.528
    Flashpoint 38°C
    Solubilityinwater Insoluble
    Vaporpressure 8 mmHg (25°C)

    As an accredited 2-Chlorofluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 2-Chlorofluorobenzene is packaged in a 500 mL amber glass bottle with a secure screw cap, labeled with hazard symbols.
    Shipping 2-Chlorofluorobenzene is shipped as a hazardous material, classified under UN2380. It must be packed in tightly sealed containers, protected from moisture and incompatible substances. Transport requires compliance with local and international regulations, including clear labeling and accompanying safety documentation, to ensure safe handling and prevent environmental contamination or accidental exposure.
    Storage 2-Chlorofluorobenzene should be stored in a cool, dry, and well-ventilated area, away from sources of ignition and incompatible materials such as strong oxidizers. Keep the container tightly closed and correctly labeled. Store in a chemical-resistant container, protected from direct sunlight and moisture. Use appropriate secondary containment to prevent spills or leaks, and ensure emergency procedures are in place.
    Application of 2-Chlorofluorobenzene

    Applications of 2-Chlorofluorobenzene in Industrial Manufacturing

    2-Chlorofluorobenzene serves as a key intermediate in several high-value chemical synthesis chains, providing a stable halogenated aromatic structure essential for downstream transformations in agrochemicals, pharmaceuticals, dyes, and advanced materials production. Our direct manufacturing expertise enables reliable supply and consistent quality tailored to demanding industrial production standards.

    1. Agrochemical Active Ingredient Intermediate Synthesis

    Manufacturers utilize 2-chlorofluorobenzene as a building block for trenching specific active ingredients in crop protection chemistry, particularly in the synthesis of selective herbicides and insecticides. This raw material enables precision in halogen orientation during nucleophilic aromatic substitution, contributing crucially to efficacy and regulatory compliance of evolved pesticide molecules.

    Industry compliance standards

    • FAO/WHO International Code of Conduct on Pesticide Management
    • EPA 40 CFR Part 180 – Tolerances and exemptions for pesticide chemical residues
    • EU Regulation (EC) No 1107/2009 on Plant Protection Products
    • ISO 9001:2015 Quality Management Systems for industrial chemical production

    Typical usage ratio

    • 8–20% w/w as a limiting intermediate in multi-step synthesis; ratio depends on the molecule design and target halogenation pattern

    Downstream process integration

    • Charge to batch or continuous reactors at the halogenated aromatic formation step; undergoes nucleophilic substitution, Friedel-Crafts reactions, or direct coupling, typically under controlled temperature and catalyst conditions

    Final product types

    • Triazine and substituted aniline-based herbicides
    • Pyrazole and phenoxy insecticide actives
    • Formulated emulsifiable concentrates and wettable powders
    • Microencapsulated crop protection formulations

    2. Pharmaceutical Intermediate for Active Substance Synthesis

    In pharmaceutical synthesis, this halogenated benzene ring offers a foundation for selective fluorination and chlorination patterns in the structure-activity relationship optimization of APIs. Process chemists depend on its predictable reactivity profile to access intermediates for antihypertensive and central nervous system drug ingredient synthesis, while keeping within regulated impurity limits and GMP frameworks.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice for Active Pharmaceutical Ingredients
    • United States Pharmacopeia (USP), European Pharmacopoeia (Ph. Eur.) synthesis guidelines
    • FDA 21 CFR Part 211 – Current Good Manufacturing Practice for Finished Pharmaceuticals
    • REACH (EC 1907/2006) chemical registration and documentation

    Typical usage ratio

    • 3–12% w/w in stepwise synthesis of API intermediates; the loading varies according to desired step yield and side reaction suppression

    Downstream process integration

    • Introduction during early-to-mid stage aromatic ring substitution or as a precursor for Suzuki, Buchwald-Hartwig, or SNAr couplings, with precise dosing controlled by process analytics

    Final product types

    • Antihypertensive agent intermediates (e.g., sartans)
    • Central nervous system drug precursors
    • Final API bulk crystals post-purification
    • Regulatory standard reference compounds

    3. Dye and Pigment Precursor Manufacturing

    Producers in the dyes and pigments industry choose 2-chlorofluorobenzene for manufacturing specialty colorants, where controlled halogen introduction improves both colorfastness and binding to textile fibers and polymers. Its unique reactivity provides tailored chromophore substitutions demanded by high-specification printing inks and plastic coloration processes.

    Industry compliance standards

    • Oeko-Tex Standard 100 for textile dye safety
    • EU REACH (EC 1907/2006) substance evaluation
    • ISO 9001:2015 Quality Management for batch traceability
    • ZDH (Zero Discharge of Hazardous Chemicals) Manufacturing Restricted Substances List for colorant raw materials

    Typical usage ratio

    • 5–15% w/w depending on the chromophore target, matrix reactivity, and final dye-color intensity requirements

    Downstream process integration

    • Used in the intermediate arylation or diazotization step, where orthogonal halogen placement determines hue and migration resistance in the resulting dye molecule

    Final product types

    • Reactive and disperse textile dyes
    • Printing ink pigments
    • High-performance masterbatch colorants for PET and polyamide
    • Industrial coatings pigment dispersions

    4. Electronic and Specialty Polymer Production

    Electronic chemical producers and advanced materials manufacturers employ 2-chlorofluorobenzene as a functional monomer precursor in the synthesis of liquid crystal intermediates and high-thermal-stability engineering polymers. Selective halogen positioning enables precise control of crosslinking and dielectric properties, critical for high-reliability device encapsulants and optical display components.

    Industry compliance standards

    • RoHS Directive 2011/65/EU and its amendments on hazardous substances
    • UL 94 for flammability of plastic materials
    • IEC 61249-2-21: Specification for base materials for printed boards
    • ISO 14001:2015 Environmental Management System for specialty chemical production

    Typical usage ratio

    • 2–8% w/w in prepolymer formulation; precise ratio customized based on targeted degree of halogen substitution and process conditions

    Downstream process integration

    • Introduced at specialty polymerization or crosslinking step; frequently used in Friedel-Crafts or direct fluorination to achieve required performance profile in downstream compounding

    Final product types

    • Liquid crystal monomers for thin-film displays
    • Polyimide resin components for flexible substrates
    • Flame-retardant polyaryletherketones
    • Photolithography chemicals for IC fabrication

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    Certification & Compliance
    More Introduction

    Understanding 2-Chlorofluorobenzene: A Look Behind the Label

    Our Perspective on 2-Chlorofluorobenzene

    Every day in production, exacting methods and strict oversight shape the purity of 2-Chlorofluorobenzene, also known as 1-chloro-2-fluorobenzene. Our chemists observe not just colorless clarity and volatility in the final product, but also the way impurities behave at trace levels. Over years of actual manufacture, this compound’s distinct properties have influenced multiple chemical routes. Many years ago, purification of halogenated aromatics often hit the wall with residual metal or uncontrolled side reactions. The process now filters through rigorous quality controls from raw material intake to post-recruitment inspection.

    Specifications That Matter

    With 2-Chlorofluorobenzene, trace chlorine and fluorine both shape the chemical’s nature. Our typical batch emerges as a clear liquid with a mild aromatic odor, handled in drums or bulk tankers. Assay levels often push above 99%, with moisture and acid content tracing down to ppm or lower. This isn’t about brochures or broad claims: every batch pulls a gas chromatography printout, driven by sharp lab teams and constant calibration. For many years, even single-digit ppm contamination forced entire runs to be stripped or recycled. We insist on tight storage parameters. Tanks need to stay shielded from heat, and every container seal gets triple-inspected to keep out dampness. No shortcuts here.

    What Critical Users Expect

    Pharmaceutical and agrochemical syntheses set the real bar for 2-Chlorofluorobenzene. Researchers come looking for a building block that won’t pull in background reactivity or destabilize further on the line. Many intermediates—especially those aiming at nitro-substitution, Grignard reactions, or nucleophilic aromatic substitution—lean on this molecule’s stability. It’s a careful balance. The ortho-orientation of chlorine and fluorine gives just enough directionality, helping downstream chemical engineers swap groups or tack on complexity in controlled steps. Every customer call focuses on reproducibility, solvent compatibility, and residue levels. We’ve seen projects tumble at the scale-up stage when suppliers couldn’t stay consistent. Reliability beats flash every time.

    In the Field: Daily Realities of Application

    Large-volume synthesis, especially in specialty polymers or crop-protection, doesn’t tolerate variation. Staff at our site know the tide of demand—sometimes spiking, sometimes grinding through long months. The sensitivity of 2-Chlorofluorobenzene’s handling mirrors the need for tight process safety. The boiling point—hovering just under 180°C—means storage tanks need robust pressure management. Over the years, we invested in sealed transfer lines and vent controls to keep emissions low. Batch documentation gets reviewed and stamped off on the floor, not from behind a remote desk.

    Customers with fine chemical projects sometimes request solid proof of trace metal residue. We run detailed ICP-OES to back up purity claims. Every rejected load costs us downtime and replacement shipment, so in-house standards usually exceed external demands. Many times, we’ve talked directly with downstream chemists, walking through spectra, handling, and even tape residue on containers. For some, our NMR and GC-MS reports settle nerves before a project moves forward.

    Why Source from a Direct Manufacturer

    Several of our customers learned the hard way with bulk traders rebranding lower-purity cuts or losing chain-of-custody. Sourcing 2-Chlorofluorobenzene directly from our line closes the gap. They see finished batch records, shipping logs, and a live view of scheduling—not just a PDF data sheet shuttled between offices. Inside our plant, we know where every drum originated, which distillation run it came from, and what test results followed. Some ask about our supply chain rigor. Before signing contract supply, auditors tour our lines, check batch logs, and ask operators about cleaning cycles. Nothing gets hidden behind email chains or faceless intermediaries.

    Differences Compared to Other Halogenated Benzenes

    Plenty of chemistries use simple chlorinated or fluorinated benzenes as starting points. 2-Chlorofluorobenzene stands apart due to its specific halogen arrangement. The ortho-positioning produces reactivity not matched by simple monochlorobenzene or fluorobenzene. We’ve watched process chemists chase regioselective substitutions, only to run into pitfalls using the wrong halogen pattern. As a manufacturer, swapping from 2-chloro or 4-chloro is not a trivial switch. Reaction rates, yields, and impurity profiles all shift noticeably. More than once, a research partner’s project timeline stretched by months, all for lack of the correct base molecule.

    Handling procedures also differ. 2-Chlorofluorobenzene tends to behave more aggressively with certain elastomers and gaskets, meaning equipment design gets an extra layer of scrutiny. Storage with standard rubber stoppers or loose seals risks leaks and off-odors, harming safety and reliability down the line. Every time a drum leaves our warehouse, our QA checks both chemical purity and container integrity.

    Pitfalls of General Sourcing and Out-of-Spec Material

    So much in chemical production comes back to consistency. In the past, we’ve received calls from teams stymied by uneven color, persistent off-smells, or batch-to-batch assay drift. Many times, they assumed any “chlorofluorobenzene” would slot into downstream synthesis. The truth: even minor impurities—those that wouldn’t register on basic tests—wreak havoc in precision work. Our plant takes each deviation seriously since one contaminated tankload cascades through the supply chain. The work never ends; staff rotate through equipment checks and retrain on manual shutdowns in case of abnormal pressure or odd readings. Over the past year, raised vigilance over trace contamination changed our raw material intake protocol, too. Our team screens every new supplier’s own chain for unknown additive residues or transport history.

    Cost-cutting and backfilled supply may shave pennies on the invoice, but cleanup and process delays multiply the total outlay. We get called to troubleshoot stuck reactions, investigate polymer discoloration, or explain low yields—all because material drifted away from controlled manufacturing standards. Real losses stack up in a day, not over quarters. We keep close tabs so partners down the line can trust incoming lots match every line item on the spec sheet.

    Evolution of Quality Control: From Bench to Bulk

    Two decades ago, plant staff used basic distillation columns with little feedback other than boiling range and refractive index. Now, on-line monitoring and digital controls let us tweak cuts with fine detail. Batch data and every shift’s sign-offs get logged electronically. If discrepancies arise, the records trace back to minute-by-minute conditions, not just an old logbook. In-house labs run multiple cross-method checks—GC for purity, Karl Fischer for water, sometimes even elemental analysis for full closure. We’ve had operators catch anomalous readings outside normal working hours; one call and the response team swarms to track the irregularity. Every flaw left unaddressed threatens the next ten batches.

    Certain customers want to know about historical deviations, and we share outcomes directly. Over the years, we’ve learned that full transparency cements trust faster than polished pitches. When introducing new purification hardware, we invite third-party verifiers to test output and compare historical consistency. It’s not about glossy certificates or slogans. Each improvement grows from that day’s breakdown, operator feedback, and updated technical resources.

    Product Applications: Experience from the Frontline

    Over time, 2-Chlorofluorobenzene developed deep roots in the synthesis of other fine chemicals. It’s not a high-visibility product itself, but it triggers key steps in making advanced herbicides, pharmaceuticals, and performance polymers. Each application presses a unique list of purity and impurity demands.

    Pharmaceutical intermediates rise and fall on reliability; dosing irregular substances into pilot reactors risks a month’s production. We hear from project managers working tight timelines, who prefer a maker willing to answer direct process questions instead of shipping cryptic purity ranges. In crop-protection, formulation teams investigate compatibility and shelf-life stability, tracing the root cause of every variance. Every drum we fill carries an implicit guarantee—a consistent, vetted, and documented chain from intake to output.

    Other uses pop up, such as custom syntheses, specialty surfactants, and controlled solvents in electronics. Novel research pushes for higher assay and lower unknown impurities. Feedback from university labs sometimes prompts us to review and refine microreactor protocols. Every reformulation passes down new requirements, from solvent-wash sequences to supply chain verification. Our flexibility grows with every challenge, but never at quality’s expense.

    Challenges We Work Through

    In recent years, the regulatory landscape circling chlorinated and fluorinated solvents grew more complex. Environmental scrutiny escalates; emissions from storage, transfer, and off-gassing enter audits and compliance reviews. In practice, that shifts how operations stack up—requiring everything from vapor recovery systems to tighter room controls. We keep training frontline teams to spot subtle leaks and escalation points, especially in summer months or high-load periods. Everyone in manufacturing knows: a single unplanned release triggers a day of cleanup and process interruption.

    Waste stream management is never an afterthought. Byproducts containing chloride or fluorine draw tighter rules each year. We custom-fit scrubbing and incineration to every run where possible, minimizing load on central treatment. Each disposal manifests a chance to review—did process control catch the anomaly early or late? Communication ties every aspect together, from desk-side managers to on-floor technicians.

    Perspective on Safe Handling

    Experience with 2-Chlorofluorobenzene teaches that safe handling isn’t just about printed rules. Operators pick up on the tactile details of drum movement, vapor whiff, or early morning temperature shifts. Tanks get shadowed for condensation and odd pressure swings. In the lab, small mishaps—a spilled drop or uncapped container—draw quick correction. Every team member cycles through chemical safety drills and incident reviews. Over dozens of audits, internal and external, one fact never varies—real risk recognition grows from regular contact, not just orientation materials.

    Shift supervisors know the hard lessons from inadequate PPE or missed vent controls. Minor exposure, even unreported, carries through to morale and trust. We invest in updated protective kit and real-world scenario training, so everyone from the loading dock to the formulation suite reads cues and flags new risks.

    Responding to Customers in Real Time

    Managing 2-Chlorofluorobenzene production isn’t static. Customer requirements change, specs tighten, lead times contract. Our team meets partners face-to-face and on video calls, discussing unique project hurdles. Sometimes a late-day lab test resolves a looming shipment issue. Other times, overnight express samples blaze a trail for an urgent new synthesis. We don’t wait for problems to pile up. Each request triggers a feedback cycle—with direct lines to production, QA, and technical teams.

    Sometimes a project pivots sharply—call-offs, spec changes, batch rescheduling—and we flex response across plant and logistics. Our focus stays not just on fulfilling current demand but strengthening methods for the next twist or upturn. Customers get more than a transaction; they tap into cycles of hard-won process understanding.

    The Bigger Picture: Commitment Over Time

    Every drum of 2-Chlorofluorobenzene carries a trace of shared effort. Quality evolves from hundreds of daily decisions. People running the distillation column, scheduling new runs, or cross-checking analytical results each carry responsibility. Improvements don’t appear all at once. They come from root-cause analysis, direct experience with bad batches, and listening to what went wrong along the way.

    From initial intake of raw aromatics, through multiple controlled reactions, to purification and packing, the stakes stay high. Any slip travels down the line—into another company’s project, another lab’s breakthrough, or a new class of advanced materials. Every day, the same priorities echo: keep product integrity strong, learn from every mishap, and answer every question with full detail. Customers know they can reach directly for in-depth clarification; lines of communication stay open from batch to batch.

    Conclusion: Speaking Plainly about What We Do

    Producing 2-Chlorofluorobenzene isn’t about buzzwords or glossy pitch decks. It’s the culmination of sweat, inspection, technical discussion, and hands-on know-how. End users don’t settle for less than trackable provenance, detailed specs, and responsive help when something goes sideways. Those of us with years in the plant feel pride not just in the material delivered, but in the routines that add up to reliable supply. Each ton that leaves our site reflects lived experience, lessons learned, and an ongoing promise to every chemist counting downstream.

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