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HS Code |
685255 |
| Productname | 2-Chlorobenzoyl Chloride |
| Casnumber | 1988-8 |
| Molecularformula | C7H4Cl2O |
| Molecularweight | 175.02 g/mol |
| Appearance | Colorless to pale yellow liquid |
| Density | 1.38 g/cm³ |
| Meltingpoint | -8 °C |
| Boilingpoint | 228 °C |
| Purity | Typically ≥ 98% |
| Solubility | Decomposes in water; soluble in organic solvents |
| Refractiveindex | 1.571 |
| Flashpoint | 92 °C |
| Synonyms | 2-Chlorobenzenecarbonyl chloride |
| Unnumber | UN 2507 |
As an accredited 2-Chlorobenzoyl Chloride factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | Amber glass bottle, 500 mL, tightly sealed with a PTFE-lined cap, labeled with hazard warnings and chemical identification details. |
| Shipping | 2-Chlorobenzoyl Chloride is shipped as a hazardous chemical under UN 2506, Class 8 (corrosive), Packing Group II. It must be packed in tightly sealed containers, protected from moisture, and clearly labeled. Transportation should comply with international regulations, avoiding contact with incompatible substances and ensuring proper ventilation during transit. |
| Storage | 2-Chlorobenzoyl chloride should be stored in a tightly closed container, in a cool, dry, and well-ventilated area, away from moisture and incompatible materials such as strong bases, alcohols, and amines. It must be kept away from sources of ignition and direct sunlight. Proper labeling and secondary containment are recommended to prevent accidental contact or leaks. |
Applications of 2-Chlorobenzoyl Chloride in Industrial ManufacturingAs a specialized manufacturer of 2-Chlorobenzoyl Chloride, we provide this high-purity raw material to support demanding downstream synthesis in select industrial sectors. Our production quality and regulatory alignment ensure consistent integration into advanced chemical manufacturing, with applications driven by rigorous industry requirements, precise dosage control, and critical process fit. 1. Active Pharmaceutical Ingredient (API) Synthesis for Oncology DrugsLeading pharmaceutical producers rely on our material as a vital acylating agent in the construction of complex heterocyclic intermediates, particularly for the synthesis of selective kinase inhibitors and anti-cancer drug substances. Reactivity and purity requirements are stringent, as the compound often introduces a chlorophenyl moiety to core scaffolds in multi-step synthetic sequences. Process chemists value predictable reactivity for large-scale batch, semi-batch, or continuous flow operations, directly linking material traceability to API registration files. Industry compliance standards
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2. Agrochemical Intermediate Production (Herbicide and Fungicide Synthesis)Many crop protection compound manufacturers employ this chemical for efficient benzoylation steps when forming key intermediates used in the synthesis of aromatic amides and esters prevalent in modern herbicide and fungicide formulations. Its role centers on enabling selective substitution reactions, necessary for building active moieties while conforming to process safety and environmental protocols, particularly when manufacturing in sealed reactor systems with active off-gas treatments. Industry compliance standards
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3. Photographic & Imaging Chemical ManufacturingProducers of specialty chemicals for photographic films, X-ray imaging, and high-resolution printing utilize this molecular building block as a chlorinated acyl source when designing photosensitive resins and polyester intermediates. Its chlorinated aromatic structure imparts fine-tuned reactivity required for the synthesis of compounds that govern the optical properties and shelf stability of photosensitive emulsions. Process integration is tightly linked with in-line quality monitoring for color stability and controlled light response. Industry compliance standards
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4. Fine Chemical Synthesis for Specialty Aromatic CompoundsManufacturers developing niche aromatic chemicals for high-performance materials, dyes, and advanced coatings rely on this reagent to facilitate controlled chlorobenzoylation reactions. Here, product purity and selective reactivity play a central role in overall process efficiency, particularly when manufacturing custom intermediates where impurity profiles directly impact the optical, colorfastness, or conductivity attributes of the end-user formulation. Batch-to-batch consistency and trace-level impurity control remain primary process goals. Industry compliance standards
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We have been developing and manufacturing 2-Chlorobenzoyl Chloride for years to support the dynamic needs of the chemical industry. This isn’t just another line item on our catalog—it’s a specialty intermediate that shapes many high-demand downstream products. Our team in the plant has refined the process to make sure quality and consistency stay tight with every ton. Inconsistent material can throw an entire synthesis chain off course. For us, chemical manufacturing isn’t just batch and ship. Batch records tell the story, but hands-on time with the reactors and distillation units really reveal how small changes in raw material and processing can affect purity or stability.
2-Chlorobenzoyl Chloride carries the molecular formula C7H4Cl2O. The structure includes a benzene ring substituted at the 2-position with chlorine, and a benzoyl chloride group attached. This arrangement creates a highly reactive acid chloride, making it well-suited for acylation reactions. From a manufacturer’s standpoint, it’s not just the chemical reactions on paper that matter, but also how the material performs during large-scale synthesis—batch-to-batch stability, reactivity, and handling all take on real-world significance.
In our manufacturing experience, impurities like residual benzoic acid or incomplete chlorination can impact reactivity or downstream purity. Just a couple of tenths of a percent off-spec can mean extra work in purification for a downstream user. That is why we invested in continuous inline monitoring over the years and adapted our chlorination step to minimize over-chlorination or unwanted side products.
The way 2-Chlorobenzoyl Chloride moves through the industry starts with its foundational role as an acylating agent. You see its fingerprints in the pharmaceutical space, where it acts as a building block to assemble more complex molecules. This structure lends itself to synthesis of various benzamide and ester derivatives. We work with pharmaceutical ingredient producers who use it in creating core intermediates for active pharmaceutical ingredients, leveraging the electron-withdrawing effect of the 2-chloro group to steer reactions where they need them.
In agrochemicals, it’s often utilized to build up the backbones for new fungicides and herbicides. A producer of crop protection chemicals may react it with various amines or alcohols to tailor molecular activity, and that demands reliable consistency in the starting raw material. This product enables the precise construction of target molecules—without stable input, the cost of screening and process troubleshooting can jump dramatically.
Dye and pigment manufacturers comprise another strong user base. Here, 2-Chlorobenzoyl Chloride serves as a coupling agent—its reactivity with aromatic amines or alcohols lets chemists attach specific groups to benzenoid frameworks, giving new color and stability properties needed for high-performance pigments.
Day-to-day life in the plant is all about recognizing variability and swiftly correcting it. For those actually synthesizing or transforming 2-Chlorobenzoyl Chloride, the difference between a material designed for laboratory scale and one proven at industrial scale becomes clear quickly.
In our own operation, control over chlorination and purification steps directly influences purity, color, and stability. Even trace water in the final product creates issues in certain reactions, not to mention storage. Handling on a fast-moving drum filling line demands focus so that the corrosive nature of the product doesn’t become a hazard—our plant engineers retooled the loading stations several times to keep employees safe and minimize downtime. The formula may look simple, but execution matters.
Our batches range from several hundred kilograms up to several tons. Each run starts with high-purity ortho-chlorobenzoic acid and phosgene-free chlorination, managed with constant feedback. The resulting 2-Chlorobenzoyl Chloride gets distilled under reduced pressure to cut down on decomposition risks. We ship it in lined steel drums or intermediate bulk containers designed for corrosive liquids, and full chain-of-custody tracking follows each shipment from our tank farm to the client’s site.
Plenty of acyl chlorides fill similar roles, from benzoyl chloride to 4-chlorobenzoyl chloride and beyond. Lab books typically outline reactivity trends, but industry experience highlights subtler points. 2-Chlorobenzoyl Chloride stands apart due to its ortho-chloro substitution, which shifts reactivity and steers regioselectivity for follow-up reactions. The ortho-chloro group introduces steric hindrance and enhances electron withdrawal, leading to unique reaction pathways compared to the para-substituted or unsubstituted versions.
From an operational view, another key point is handling and storage. We have seen 4-chlorobenzoyl chloride and plain benzoyl chloride sometimes develop impairment in color or purity due to differing rates of hydrolysis or reaction with steel drum linings. 2-Chlorobenzoyl Chloride, in comparison, displays slightly more stability in closed systems, assuming moisture exclusion is tight. We always recommend nitrogen blanketing and dedicated corrosion-resistant transfer lines.
During scale-up projects with customers, distinctions appear in required reaction times, selectivity, and yields. Certain pharmaceuticals rely specifically on the ortho substitution for their pharmacological effects. Attempts to substitute with meta or para isomers frequently force re-optimization of syntheses and purification steps, losing both product and production hours.
We manufacture 2-Chlorobenzoyl Chloride to tight specifications determined through years of real-life feedback from polymer, pharmaceutical, and crop science clients. Typical product batches offer assay levels above 99 percent, with acid content and moisture controlled well below what would create side reactions in typical uses. Consistent, pale-yellow appearance assists with process monitoring, though we caution users not to rely solely on visual inspection—analytical confirmation remains critical for formulation and scale-up work.
A lot of the learning comes from discussions with our clients’ process chemists and plant engineers. New downstream applications push us to reduce trace metal content or chlorine residual even further. By working jointly with end users during pilot trials and sampling campaigns, we tighten up the process and pass that improved material along for the next campaign.
Each production campaign follows a traceable, audited supply chain that begins with raw material verification and finishes with container sealing and digital documentation. Quality assurance teams sample each lot for GC analysis, HPLC impurity profiling, and Karl Fischer moisture testing right after distillation. Extra controls, such as headspace analysis for residual volatility, help support stricter downstream requirements. When new impurities pop up, analysis gets updated and communicated directly with the client, keeping everything transparent and avoiding surprises in the client’s reactor.
Safe handling and shipping demand real discipline with acyl chlorides like this. Training programs cover proper PPE, emergency neutralization, and transfer procedures. Our containers use special liners to avoid corrosion, and packages are clearly labeled for regulatory and user clarity. By running a closed-loop system at the production line, we minimize exposure risk for the workforce, while also improving efficiency by reclaiming unreacted feedstock.
Our direct involvement in global shipments gives us a clear picture of regulatory protocols both at home and overseas. Chemical control laws, transport codes, and client-specific requirements can vary quite a bit between countries. For 2-Chlorobenzoyl Chloride, we work within REACH, TSCA, and equivalent local certification frameworks, ensuring that our documentation lines up from manufacturing through final delivery.
Exporting acyl chlorides raises its own headaches. Some destinations need purity certification down to the tenth percentile, while others impose real-time updates on chain-of-custody and security protocols. Satisfying these requirements means maintaining open communication with our freight partners and keeping compliance teams ready to adjust to shifting global rules.
Environmental controls are a core part of chlorinated intermediate production. Over the years, we watched the industry raise the bar higher—now, every discharge must be managed with precision. Unlike simple distillation by-products, chlorinated wastes can require neutralization with specialized bases, or in some cases, careful incineration. The modern plant’s waste control system must run alongside, not after, mainline production, to prevent process bottlenecks.
We manage closed-loop solvent recovery whenever possible. Spent process liquids get separated, neutralized, and sent for offsite disposal or reclaimed in our own units. Scrubbing towers on our vent lines pull residual HCl vapors before off-gas leaves the site. By investing here, we have improved both compliance and efficiency over the long term. Experience reveals where small leaks or procedural slip-ups might trigger releases, so we run live monitoring where personnel and product streams intersect.
Manufacturers know the basics, but the fine details around 2-Chlorobenzoyl Chloride storage and use carry big weight on safety, yield, and quality. We share storage protocols with end users, highlighting the importance of dry, cool areas and tightly sealed containers. Nitrogen blanketing remains standard, and dedicated transfer equipment eliminates cross-contamination. Every level of the supply chain—from plant operator to warehouse staff—gets trained on what to watch for in case of leaks, spills, or decomposition.
We provide technical guidance on integrating our product into continuous processes or standard batch production, with on-call support during customer scale-up. A lot of troubleshooting happens right before launch, often around impurity carryover, material compatibility, or reaction exotherms. Knowledge shared across industries has practical benefits: dye and pigment producers facing decomposition issues in older equipment, for example, discover unexpected improvements by switching to updated handling protocols we helped develop together.
Only by working hands-on, side-by-side with customers do we find the flexible, on-the-ground solutions needed for successful integration of 2-Chlorobenzoyl Chloride in production pipelines. Where one company’s process needs a little extra stabilization, another might need detailed impurity tracking or assistance requalifying equipment. That real dialog between manufacturer and user closes the loop, shaping not just what comes out of the reactor, but also how it’s applied in new and innovative products.
Change remains constant in the specialty chemicals business. New regulations emerge, market dynamics shift, and customer requirements become more challenging every year. In our experience, adapting the 2-Chlorobenzoyl Chloride production pipeline doesn’t end after the initial plant scale-up. Ongoing investments in control automation, analytics, and workforce training push us to improve quality and response times. We also track the steps competitors and our own suppliers take, since disruptions upstream can ripple through the supply chain.
As more customers move towards green chemistry and safer alternatives, keeping open lines of communication about product lifecycle and best practices drives continual improvement. Environmental pressures encourage us to minimize solvent loss, improve recycling rates, and work hard to reduce any waste generation at source. Our field engineers and product managers gather data directly from the marketplace and translate that back into operational improvements—be that a new purification column, a batch tracking system, or an adapted cleaning procedure between product runs.
In this business, focus lies not just in making a molecule, but in supporting every step from raw materials to final application. 2-Chlorobenzoyl Chloride’s importance stretches from crop science to pharma to dyes, locked in by the unique chemistry of the ortho-chloro substitution and real-world reliability under pressure. Years of hands-on manufacturing, troubleshooting, and partnership have shown us that success comes from consistency, transparency, and a sharp eye for emerging challenges. Whether a client’s concerns revolve around purity, safety, throughput, or compliance, our approach remains grounded in practical know-how and a commitment to responsible progress.
By listening to clients and building on direct plant experience, we keep improving the role 2-Chlorobenzoyl Chloride can play across multiple industries. Continuous feedback, technical rigor, and steady investment in people and process distinguish what we offer from off-the-shelf alternatives. The journey from initial synthesis to integration in cutting-edge molecules never follows a straight line, but with the right expertise and attention to detail, the pathway proves navigable and rewarding for all involved.
