Products

2-Chlorobenzotrifluoride

    • Product Name: 2-Chlorobenzotrifluoride
    • Alias: o-Chlorobenzotrifluoride
    • Einecs: 202-396-2
    • Mininmum Order: 1 g
    • Factroy Site: Yudu County, Ganzhou, Jiangxi, China
    • Price Inquiry: admin@ascent-chem.com
    • Manufacturer: Ascent Petrochem Holdings Co., Limited
    • CONTACT NOW
    Specifications

    HS Code

    464381

    Chemicalname 2-Chlorobenzotrifluoride
    Casnumber 88-16-4
    Molecularformula C7H4ClF3
    Molecularweight 180.56 g/mol
    Appearance Colorless liquid
    Boilingpoint 145-147 °C
    Meltingpoint -30 °C
    Density 1.36 g/cm3 at 20 °C
    Refractiveindex 1.491 at 20 °C
    Flashpoint 45 °C (closed cup)
    Solubilityinwater Insoluble
    Vaporpressure 5 mmHg at 25 °C

    As an accredited 2-Chlorobenzotrifluoride factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing The 2-Chlorobenzotrifluoride is packaged in a 500 mL amber glass bottle with a secure screw cap and hazard labeling.
    Shipping 2-Chlorobenzotrifluoride is typically shipped as a liquid in secure, labeled containers compliant with international chemical transport regulations. It should be protected from heat, ignition sources, and physical damage during transit. The shipping documentation must include appropriate hazard classification—flammable liquid, UN 2234—and emergency contact details per applicable standards such as DOT and ADR.
    Storage 2-Chlorobenzotrifluoride should be stored in a tightly closed container, in a cool, dry, well-ventilated area away from incompatible substances such as oxidizing agents. Protect from sources of ignition and direct sunlight. Store at room temperature and avoid excessive heat. Proper labeling and secondary containment are recommended to prevent leaks or spills. Keep out of reach of unauthorized personnel.
    Application of 2-Chlorobenzotrifluoride

    Applications of 2-Chlorobenzotrifluoride in Industrial Manufacturing

    As a direct manufacturer, we supply 2-Chlorobenzotrifluoride for use in a range of established industrial synthesis chains. Our product is specified by global formulators looking for chlorinated aromatic intermediates featuring strong electron-withdrawing attributes, which enable reliable performance in several advanced manufacturing routes. Each industry segment below outlines concrete application practices, standards, and production parameters as used by commercial operators.

    1. Agrochemical Synthesis: Intermediate for Herbicide and Insecticide Production

    Major crop protection product lines rely on this compound as a key halogenated aromatic intermediate during the multi-step synthesis of selected active ingredients. It imparts high chemical stability during nitration, amination, and subsequent derivatization stages. Global suppliers incorporate this raw material in both classical and modern synthesis for fluorinated phenoxy herbicides and selected non-systemic insecticides, providing a dependable aromatic backbone for further transformation.

    Industry compliance standards

    • OECD Principles of Good Laboratory Practice
    • ISO 9001:2015 for Manufacturing Quality Management Systems
    • EU Regulation (EC) No. 1107/2009 for pesticide active substance approval
    • China GB 20810-2006 (Pesticide Manufacturing)

    Typical usage ratio

    • Employed at 0.6–1.5 molar equivalents as aromatic substrate per downstream active ingredient batch; adjustment based on target molecule and reaction yield

    Downstream process integration

    • Introduced during initial halogenation or acylation step in multistep synthesis of phenoxyfluorinated herbicides and select insecticides, preceding condensation or rearrangement operations

    Final product types

    • Selective herbicide actives (e.g., fluorinated phenoxy derivatives)
    • Insecticidal intermediates for final API crystallization

    2. Pharmaceutical Intermediate for Active Ingredient Development

    Several fluorinated or chlorinated pharmaceutical compounds utilize this molecule as a controlled intermediate. Its trifluoromethyl-substituted ring enables robust transformation via nucleophilic aromatic substitution or metal-catalyzed coupling, supporting downstream preparation of advanced APIs in anti-inflammatory and anti-allergy drug classes. Pharmaceutical manufacturers require traceable, consistent purity levels for reaction reproducibility and compliance during GMP synthesis campaigns.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice for Active Pharmaceutical Ingredients
    • Chinese Pharmacopoeia (2020 Edition, Part II) for intermediate control
    • US FDA 21 CFR Part 211 (Current Good Manufacturing Practice for Finished Pharmaceuticals)
    • EMEA Guideline on the Specification Limits for Residues of Metal Catalysts or Metal Reagents (EMEA/CHMP/SWP/4446/2000)

    Typical usage ratio

    • Used at 1.0–1.2 equivalents relative to organometallic or nucleophilic agent per multi-kilogram API process batch; varies by final API yield optimization

    Downstream process integration

    • Charged during intermediate synthesis—metal-catalyzed coupling or nucleophilic aromatic substitution stages, prior to core structure assembly and further derivatization steps

    Final product types

    • Non-steroidal anti-inflammatory API intermediates
    • Second-generation antihistamine intermediates
    • Key intermediates for fluorinated pharmaceutical compounds

    3. Specialty Coatings: Synthesis of Performance Resins and Monomers

    This aromatic halide plays a strategic role in the production of fluorinated resin precursors, especially in wire enamel and industrial coating systems requiring enhanced weathering and chemical resistance. Resins derived from its structure exhibit improved durability under UV and solvent exposure, especially after copolymerization or polycondensation. Manufacturers depend on its chemical stability for formulations targeting electronics, aerospace, and high-speed rail applications.

    Industry compliance standards

    • REACH Registration, Evaluation, Authorisation and Restriction of Chemicals (EC No. 1907/2006)
    • RoHS Directive 2011/65/EU for electronics coatings
    • ASTM D3029-13 for Polymeric Coating Performance
    • GB/T 25251-2010 (China coating industry standard)

    Typical usage ratio

    • Introduced at 0.5–1.5% by resin mass depending on resin type (polyester, epoxy) and crosslink density targeted

    Downstream process integration

    • Fed into monomer synthesis prior to polycondensation for specialty resin formation or as building block for trifluorinated monomer functionalization in topcoat resin lines

    Final product types

    • High-durability wire enamel coatings
    • Weather-resistant architectural topcoats
    • Electronics insulating resins

    4. Fine Chemical Synthesis: Precursor in Dye and Pigment Manufacturing

    Producers employ this material to introduce specific chlorine and trifluoromethyl substitution patterns into high-stability dye and pigment molecules. Its electron-withdrawing effects facilitate targeted coupling reactions during azo dye and functional pigment core formation. The result supports the performance of finished molecules in automotive, printing, and plastics coloration applications, particularly where UV durability is required.

    Industry compliance standards

    • ISO 9001:2015 certified quality management for colorant production
    • EN 71-3:2019 for pigments in toys and children’s products
    • REACH Annex XVII compliance for pigment raw materials
    • China HG/T 4344-2012 standard for dyes and pigments

    Typical usage ratio

    • Applied at 0.8–1.3 molar equivalents relative to diazonium or coupling agent in pigment batch syntheses; ratio adjusted for required hue and yield

    Downstream process integration

    • Participates as nucleophilic substrate during electrophilic aromatic substitution, forming key intermediates for azo and anthraquinone dyes before further purification and dispersion

    Final product types

    • Lightfast pigments for plastics and automotive coatings
    • Printing ink colorants
    • Functional dyes for high-temperature textile processing

    5. Electronics and Semiconductor Chemicals: Sourcing for Halogenated Building Blocks

    In advanced electronics production, this compound acts as a raw material for synthesizing high-performance intermediates used in liquid crystal display (LCD) monomers and semiconductor etching agents. Its high purity and well-defined substitution pattern enable controlled introduction into reaction stages requiring precise halogenated aromatic structures. Leading manufacturers value these attributes when formulating low-impurity, high-reliability electronic chemicals for integrated circuit fabrication and flat panel displays.

    Industry compliance standards

    • IEC 61249-2-21:2017 for halogen-free and low-halogen electronic materials
    • JEITA ET-7400 (Japan Electronics and Information Technology Industries Association for chemical control)
    • ISO 14001:2015 for environmental management in electronics chemical plants
    • REACH (EC) No 1907/2006 for manufacturing and use in Europe

    Typical usage ratio

    • Integrated at 0.7–1.2 molar equivalents per downstream monomer or etchant precursor; manufacturers can adjust this based on targeted substrate purity and downstream impurity concerns

    Downstream process integration

    • Feeds directly into multi-step synthesis chains for fluorinated monomer units in display films or as functional raw material for custom etching molecule preparation

    Final product types

    • LCD monomers and oligomers
    • Halogenated etching agents for semiconductor fabrication
    • Specialty electronic chemicals for flat panel manufacturing

    Free Quote

    Competitive 2-Chlorobenzotrifluoride prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please contact us at +8615365186327 or mail to admin@ascent-chem.com.

    We will respond to you as soon as possible.

    Tel: +8615365186327

    Email: admin@ascent-chem.com

    Get Free Quote of Ascent Petrochem Holdings Co., Limited

    Flexible payment, competitive price, premium service - Inquire now!

    Certification & Compliance
    More Introduction

    2-Chlorobenzotrifluoride: A Practical Look from the Manufacturer’s Floor

    Everyday Chemistry in Action

    Walking through our plant, the sight of 2-Chlorobenzotrifluoride flowing through clean stainless lines is a small reminder of how solid chemical engineering shapes daily manufacturing. We know 2-Chlorobenzotrifluoride by its CAS number (98-56-6) and keep it ready under the model name CBT-2. Our technical staff recognize it immediately: a clear, colorless liquid, aromatic in scent, with a formula of C7H4ClF3.

    Purity and Handling, Not Just Numbers

    We control the purity to a minimum of 99.5%. That’s not a marketing phrase—we keep GC instrumentation running daily, calibrate our reference standards, and clean glassware because trace moisture or other halides risk fouling entire downstream reactions for clients. The 2-Chlorobenzotrifluoride leaves our warehouse mostly in 200 kg drums but we fill smaller containers for labs and scale-up work. Typical physical constants: boiling point around 139°C, density close to 1.36 g/cm³ at ambient, refractive index for those calibrating analytical equipment. A purity report is just the start. Each batch runs through a hands-on visual check for color, cloudiness, and any hint of contamination. Plant operators—some with years of experience—know what a good lot should look and smell like, not just what appears in data rows.

    What Sets 2-Chlorobenzotrifluoride Apart

    Makers in the fine chemical, agricultural, and pharmaceutical sectors look for scalable, consistent intermediates. The trifluoromethyl group—CF3—presents a powerful electron-withdrawing handle, changing reactivity in a useful way. We’ve run comparisons with plain chlorotoluenes, difluorinated analogs, or various halogenated benzenes. None deliver the same combination: relatively high chemical stability, solvent value for specialty formulations, and a key selectivity as a precursor.

    What we witness in the plant: the CF3 group changes the electron density on the phenyl ring. This makes nucleophilic substitution more predictable compared to compounds like monochlorobenzene or chlorotoluene. Clients needing to build out more complex heterocycles get a smoother ride. While some competing intermediates can struggle under the harshness of certain couplings, 2-Chlorobenzotrifluoride handles Grignard and organolithium steps better—a practical detail only evident once you’ve been inside a real synthetic campaign.

    We have watched our partners scale up crop protection ingredients and run pilot solvent blends—all leaning on the stability and reactivity balance of this compound. That’s why more than just a structure, its real benefit comes from both reactivity and reliable performance under bulk processing pressures.

    Applications That Drive Real-World Output

    Much of the world’s pesticide and herbicide R&D draws on intermediates like this. We’ve supported multiple agrochemical launches, building specialty substituted anilines and benzamides. The fluorinated ring protects certain molecular sites in the ultimate active ingredients, boosting their field lifetimes. In dye manufacturing, our product opens up access to high-performance specialty pigments. The aromatic nature of 2-Chlorobenzotrifluoride allows robust diazotization, which then leads to brighter azo dyes.

    For pharma work, 2-Chlorobenzotrifluoride acts as a stepping stone, fitting into arylation and cross-coupling reactions with modern catalytic systems. Medicinal chemists, aiming for fluorinated or chlorinated motifs, need materials that hold up under pressure. Many rely on our compound for its low tendency to form stubborn byproducts. Our technical service team has visited customer sites to troubleshoot and verify: less waste, less column loading, and higher purity isolations versus simpler aryl chlorides.

    Beyond synthesis, solvent formulators opt for this compound where others fall short. Its relative volatility and solvent power make it a handy replacement for traditional aromatic solvents that have more environmental or regulatory issues. Clean burning, high purity, and controlled physical properties mean cross-industry workers can use it with minimal process adjustment.

    Practical Differences from Similar Compounds

    Comparing 2-Chlorobenzotrifluoride with similar substances like 4-Chlorobenzotrifluoride or o-chlorotoluene, experience from both the bench and the plant shows clear distinctions. Polarity and boiling point give different evaporation profiles and isolation tricks. Our engineers have run side-by-side trials. They report less fouling of equipment and easier phase separation during work-ups versus closely related solvents. Some industry partners previously relied on dichlorinated or difluorinated benzenes, hoping for budget savings. Many returned, noting that yields drop and waste increases—offsetting any up-front price difference. The unique combination of trifluoromethyl and chlorine in the ortho position keeps reactivity at a sweet spot for many modern synthetic methods.

    We’ve heard frequently that using less-refined grades from non-specialist vendors often means more time spent filtering, post-purification, and dealing with residue in reactors. This costs more, not less, in the long run. The cost of off-spec batches—something seldom mentioned in catalog copy—can swamp a budget when intermediates coke up or interfere with catalysts. Years of field reports show that skipping quality always backfires, even if initial testing looks passable.

    Solving Supply and Reliability Issues

    Many clients come to us after a run-in with product delays, batch-to-batch inconsistency, or mysterious trace impurities. Our factory’s integrated approach—down to the halogen and fluorination stages—means we control variables many don’t want to admit exist at all. If a flourish of pink or a sulfur odor hits at delivery, it’s not just an inconvenience. Some actives can be ruined, scaling plans derailed for weeks.

    Supplying bulk intermediates involves more than just filling barrels and printing COAs. We’ve rebuilt supply lines, put backup purification in place, and worked through critical shortages. Most outages are preventable with hands-on process management and batches traced to the minute they leave the reactor. Often, customers who once tried alternate sources return because our batch records, technical feedback, and on-the-ground expertise tighten up their own manufacturing. A high success rate starts with upstream discipline.

    Safety Isn’t Just an MSDS

    Daily work with 2-Chlorobenzotrifluoride means respecting its flammability and handling standards. Our teams bring practical experience with leaks and spills, wearing PPE, training on vapor containment, and using continuous monitoring in the filling area. Years on the shop floor focus attention: the aromatic vapors require good ventilation, and the compound’s liquid phase can challenge seals and hoses. We have overhauled procedures based on real events—something less visible outside a manufacturing facility. Local fire brigades have even visited for joint drills. Where lesser materials or hasty transfers have led to fires elsewhere, we push consistency to avoid serious incidents.

    Waste management is no less hands-on. We’ve retrofitted sections to manage trace solvent in wash streams, reducing VOC emissions and capturing most of the spent solvent for responsible destruction. Chemical workers—not just safety officers—discuss practical results daily. Plant feedback cycles catch small issues early, whether it’s about drum strength or valve wear.

    Environmental Responsibility Built-In

    Our experience with regulatory inspections, emission audits, and real sustainability pressure confirms that trifluoromethyl aromatics need close attention to air and water releases. Modern demand for greener chemistry means we track production impact at every stage: choice of raw fluorinating agents, careful containment, even spent drum recycling. Years in the business have taught us that even “acceptable” legacy practices will fall short under today’s scrutiny.

    We’ve reduced process side-products by adjusting the fluorination temperature profile, installed solvent recovery, and re-circulate process rinse water wherever possible. Full life-cycle thinking comes from understanding how aromatic fluorinated compounds can persist in the environment if mishandled. This isn’t marketing—it’s a direct response to lived regulatory pressure and periodic customer audits.

    Our team leads workshops where customers and suppliers discuss regulation trends. Sometimes new local or international limits for aromatic content or persistent organics demand a quick pivot. As actual producers, we control formula adjustments at the root—something impossible for trading-only firms. If cleaner, more renewable or lower-toxicity alternatives emerge, we pilot them in-house, reporting both the upsides and challenges back to partners.

    Quality Through Direct Producer Commitment

    Supplying 2-Chlorobenzotrifluoride since the early days, our view is different than traders or outside copywriters. Our quality policy changes based on failure analysis, not just product bullet points. In one year, a spike in trace iron due to a feedstock pump issue caused a spate of off-colored product. No other source identified it, but by running regular panel reviews and investing in inline metal analysis, we caught and addressed it before it left our gates.

    Clients regularly ask for special documentation—full impurity profiles, customized delivery packaging, or production change tracking. Our QA lab responds within a day, not a week. Many team members have come from lab roles, so communication cuts straight to technical details.

    Each time we see a new downstream use—specialty monomers, niche silicone blends, or targeted pharmaceuticals—we engage directly with the end users about their challenges. If a new process step introduces strange by-products, our technical service engineers visit and help adjust either formulation or process, based on real plant experience and shared R&D.

    Growing with Partners, Not Just Buyers

    Some presume that 2-Chlorobenzotrifluoride is simply a commodity. Yet process optimization and long-term supply hinge on a close relationship between true manufacturers and their partners. Analysts and engineers who have watched early batches with us know how unexpected details play out: an air leak on a transfer line, a minor tweak to reflux conditions, or the way containers are stacked and labeled in transit.

    Across years and economic cycles, we have steadied supply, even when raw material prices spiked or new global regulations required a quick documentation overhaul. Nearly every loyal customer has a story of a background detail—unexpected high-pressure behavior in a reactor, or a subtle batch color change—solved through direct communication and shared troubleshooting.

    The feedback loop between our production team and industrial chemists outside the gates saves both time and cost. We invest in this, keeping process notes, running extra split samples, and organizing regular plant visits for customer reps. These choices come straight from a manufacturing mindset, not a trading office.

    Reliability and Perspective: Why the Manufacturing Source Matters

    From trial lots in small glassware to tank trucks spanning continents, 2-Chlorobenzotrifluoride passes through many hands. The key differences between true manufacturing and trading sources aren’t just price or logistics—deep understanding of process history, upstream control, and willingness to adapt in real time matter most. Each plant run, every load filled, brings lessons that add up.

    Refining the process and focusing on the actual needs of real users continually pushes standards higher. We treat each ton as the next step in long partnership, not just another anonymous shipment. From troubleshooting small-lot pilot runs to supporting large-scale ongoing programs, our experience as a direct producer sets expectations higher and maintains quality, safety, and reliability at the level clients expect and demand.

    Top